1. Clinical case: multiple endocrine neoplasia type 1 (MEN 1)
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wermer syndrome ,men 1 ,prolactinoma ,prolactin ,hyperparathyroidism ,insulinoma ,proinsulin ,Physiology ,QP1-981 ,Biochemistry ,QD415-436 - Abstract
Multiple endocrine neoplasia syndrome type 1 (MEN1, Wermer syndrome) – group o а heterogeneous inherited deseases, caused by hyperlasia or neoplasia of several endocrine glands. The phenotype of MEN1 is broad, and over 20 different combinations of endocrine and non-endocrine metabolic manifestations have been described. This case demonstrates multiple formations of endocrine organs, starting non-classical with macroprolactonoma resistant to dopamine agonists therapy, other endocrine disorders developed gradually eventually: hyperparathyreoidism and hypoglycemia caused by pancreas lesions, produced proinsulin in high levels.
- Published
- 2012
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