Search

Background Somatosensory and motor dysfunctions are common after stroke, both lead to limitations in activities of daily living and social participation, there is still a lack of research evidence to analyze the relationship between the two from multiple perspectives. Objective To investigate the relationship between somatosensory and motor function among overall, upper and lower extremities in different-age-group patients within one year after stroke. Methods This prospective study enrolled the poststroke patients within one year from several hospitals in Fujian Province from October 2022 to April 2023. The sensory subscale of the Fugl-Meyer assessment (FMA-S) and the sensory subitem of National Institute of Health Stroke Scale (NIHSS) were used to evaluate the patient's somatosensory function. The motor subscale of the Fugl-Meyer assessment (FMA-M), Brunnstrom assessment, Berg Balance Scale (BBS) and the motor subitem of NIHSS were used to evaluate the patient's motor function. Modified Barthel Index (MBI) was used to evaluate the patient's activities of daily living (ADL). Hospital Anxiety and Depression Scale (HADS) was used to evaluate the patient's psychosomatic function. They were divided into two groups (the elderly group/the young and middle-aged group) according to their age, we compared the differences in general information and rehabilitation assessments between the two groups. And we analyzed the correlation between somatosensory function and motor function/ADL/psycho-psychological function. Results A total of 254 patients were included, with an average age of (61.0±12.3) years and an average disease course of 30.0 (17.0, 65.5) days. There were 112 cases (44.1%) in the elderly group and 142 cases (55.9%) in the young and middle-aged group. FMA-S and FMA-M scores were positively correlated in both groups (rs values were 0.313 and 0.171, both P

We propose a simple model of colloidal suspension, whereby individual particles change their diffusivity from high (hot) to low (cold), as the local concentration of their closest peers grows larger than a certain threshold. Such a non-reciprocal interactive mechanism is known in biology as quorum sensing. Upon tuning the parameters of the adopted quorum sensing protocol, the suspension is numerically shown to go through a variety of two-phase (hot and cold) configurations. This is an archetypal model with potential applications in robotics and social studies.

ObjectiveTo analyze the pathogenic characteristics of Salmonella senftenberg isolate causing food poisoning in Xinxiang in 2021.MethodsEpidemiological investigation of food poisoning event was performed. Pathogenic bacteria were separated and identified from 11 samples. Ten Salmonella isolates were subjected to serotyping， drug susceptibility testing， detection of characteristic gene fragments （mogA， sseL， mgtC， bcfA， araB） of 5 virulence island （SPIs） and pulsed field gel electrophoresis （PFGE） typing analysis.ResultsSerum antigenic formulas of all Salmonella isolates were 1，3，19；g，s，t Salmonella senftenberg. All Salmonella isolates were resistant to cefazolin， kanamycin， gentamicin and amikacin. Among them， two isolates from the patient feces were also resistant to ampicillin， tetracycline，doxycycline，chloramphenicol，trimethoprim/sulfamethoxazole. PFGE clustering analysis showed that there was no difference in the bands among the 10 strains （2 cases strains， 5 food strains， and 3 environmental strains）， suggesting that they were highly homologous. Five Salmonella pathogenicity island characteristic gene fragments were detected among 10 isolates.ConclusionSalmonella senftenberg caused the food poisoning event. The isolates carried 5 Salmonella pathogenicity island characteristic gene fragments and 2 isolates exhibited multi-drug resistance. Relevant departments should pay more attention to this issue.

This study aims to use attapulgite (ATT) and cement to modify loess as the lining material of landfills in loess areas and to exert the adsorption property of modified loess to ensure seepage prevention. It provides a safe, efficient, low-cost anti-seepage material for constructing a landfill in a loess area. For ATT-modified loess, when the content of ATT is less than 10%, the decrease rate of permeability coefficient is obvious, and when the content is more than 10%, the decrease rate becomes slow. After adding 5% cement on this basis, the permeability coefficient of ATT cement-modified loess is 8 × 10−8 cm/s, which meets the standard requirements (≤10−7 cm/s). The results show that the adsorption of Cu and Pb ions on ATT cement-modified loess is higher than that on pure loess. Cu and Pb ions’ adsorption rates are 99.2 and 98.5% in a single solution. In the mixed solution, the adsorption rates of copper and lead ions were 97.5 and 98.2%, respectively. Therefore, the study obtained the ratio of modified loess (85% loess + 10% ATT + 5% cement) that can not only meet the seepage prevention requirements of the landfill but also can adsorb heavy metal ions in the leachate, providing security for the landfill.

A compact electro-opto-thermal model of 2-D vertical cavity surface emitting laser (VCSEL) arrays considering the current crowding effect in each array cell is established to study the impact of oxidation aperture on the device performance. Simulated results shows that increasing oxidation aperture of array cell is helpful to improve the uniformity of current density distribution. With careful design of non-uniform oxidation aperture layout, both the uniformity of the temperature distribution and the current distribution is improved by 36.52% and 42.08%, respectively. Furthermore, 3×3 VCSEL arrays with uniform oxidation aperture (array-1) and non-uniform oxidation aperture (array-2) are fabricated and the L-I-V curves of two types of VCSEL arrays at different biases are also measured. The peak output optical power of array-2 is enhanced to 1.83mW with an improvement of 8.91% when compared with that of array-1. Moreover, the total optical output power of array-2 is always superior to that of array-1 over a wide bias current range.

Non-uniform series resistance design of VCSEL arrays is studied to improve thermally induced current bifurcation based on an electro-opto-thermal model of VCSEL arrays. Taking an 850nm VCSEL array with 4×4 cells for example, the impact of series resistance on current bifurcation is investigated. Increasmg series resistance is helpful to enhance the critical current values of current bifurcation point (Irc) and hence delay the current bifurcation phenomenon. For VCSEL array with non-uniform series resistance, Irc is increased by 28.6% and the total output optical power is enhanced by 14.3% when compared with that of VCSEL array with uniform series resistance. Therefore, non-uniform series resistance design is a better method for delaying the current bifurcation phenomenon and enhancuig the output optical power of VCSEL arrays.

Emerging multidrug resistance (MDR) in Clarireedia spp. is a huge challenge to the management of dollar spot (DS) disease on turfgrass. Insight into the molecular basis of resistance mechanisms may help identify key molecular targets for developing novel effective chemicals. Previously, a MDR isolate (LT586) of C. jacksonii with significantly reduced sensitivities to propiconazole, boscalid, and iprodione, and a fungicide-sensitive isolate (LT15) of the same species were isolated from creeping bentgrass (Agrostis stolonifera L.). The present study aimed to further explore the molecular mechanisms of resistance by using genome-wide transcriptional analyses of the two isolates. A total of 619 and 475 differentially expressed genes (DEGs) were significantly down and upregulated in the MDR isolate LT586, compared with the sensitive isolate LT15 without fungicide treatment. Three hundreds and six and 153 DEGs showed significantly lower and higher expression in the MDR isolate LT586 than those in the sensitive isolate LT15, which were commonly induced by the three fungicides. Most of the 153 upregulated DEGs were xenobiotic detoxification-related genes and genes with transcriptional functions. Fifty and 17 upregulated DEGs were also commonly observed in HRI11 (a MDR isolate of the C. jacksonii) compared with the HRS10 (a fungicide-sensitive isolate of same species) from a previous study without and with the treatment of propiconazole, respectively. The reliability of RNA-seq data was further verified by qRT-PCR method using a few select potentially MDR-related genes. Results of this study indicated that there were multiple uncharacterized genes, possibly responsible for MDR phenotypes in Clarireedia spp., which may have important implications in understanding the molecular mechanisms underlying MDR resistance.