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Introduction: Intradetrusor onabotulinumtoxinA (Botox) injections, to treat idiopathic overactive bladder (OAB), can be performed in the office setting under local analgesia alone or in the operating room (OR) under local and/or sedation. The objective of this study was to compare the symptomatic improvement in patients with OAB who underwent treatment with intradetrusor onabotulinumtoxinA injections in an in-office versus the OR setting. Methods: We performed a multicenter retrospective cohort study of women with the diagnosis of refractory non-neurogenic OAB who elected to undergo treatment with intradetrusor onabotulinumtoxinA injections between January 2015 and December 2020. The electronic medical records were queried for all the demographic and peri-procedural data, including the report of subjective improvement post procedure. Patients were categorized as either 'in-office' versus 'OR' based on the setting in which they underwent their procedure. Results: Five hundred and thirty-nine patients met the inclusion criteria: 297 (55) in the in-office group and 242 (45) in the OR group. A total of 30 (5.6) patients reported retention after their procedure and it was more common in the in-office group (8.1) versus the OR group (2.5), (P = 0.003). The rate of urinary tract infection within 6 months of the procedure was higher in the OR group (26.0 vs. 16.8, P = 0.009). The overall subjective improvement rate was 77 (95 confidence interval: 73-80). Patients in the OR group had a higher reported improvement as compared to the in-office group (81.4 vs. 73.3, P = 0.03). Conclusions: In this cohort study of patients with OAB undergoing intradetrusor onabotulinumtoxinA injections, post procedural subjective improvement was high regardless of the setting in which the procedure was performed., Author(s): James H. Ross (corresponding author) [1]; Megan Abrams [2]; Sandip P. Vasavada [3]; Jeffrey M. Mangel [2]; Cecile A. Ferrando [1] INTRODUCTION Overactive bladder (OAB) is a common and [...]

TABLE OF CONTENTS ABSTRACT 399 TABLE OF CONTENTS 400 I. INTRODUCTION 401 II. THE OBJECTIVES OF THE LEGAL-LINGUISTIC STUDY 403 III. THE SUPREME COURT'S JURISPRUDENCE ON THE CONSTITUTIONALITY OF ABORTION [...], The amicus briefs filed in landmark abortion cases before the U.S. Supreme Court serve as a barometer revealing how various constituencies talk about abortion, women, fetuses, physicians, rights, and harms over time. This article conducts an interdisciplinary legal-linguistic study of the amicus briefs that were filed in the milestone abortion cases of Roe v. Wade, Doe v. Bolton, Planned Parenthood v. Casey, and Dobbs v. Jackson Women's Health. As the first large-scale study of all amicus briefs submitted in these key cases, this article identifies the roles of amicus briefs, analyzes their rhetorical strategies, and describes how their authors engage with the Court. Using quantitative and qualitative methods, the study reveals how the discursive construction of the pregnant person, fetus, physician, and abortion as a right have evolved over fifty years and shows why these shifts matter. In so doing, this study offers historical perspectives into evolving arguments in abortion litigation, contemporaneous insights into the status of polarized abortion politics, and future implications for amicus activity and abortion advocacy.

Olivier Blanchard: fiscal policy under low interest rates The MIT Press, 2022 As is clear from the title, Professor Blanchard reevaluates fiscal policy and deficit spending under low real interest [...]

Contention is everywhere nowadays, permeating the fabric of society and constituting an important element of many different social relationships. It is also a central topic across a wide range of social scientific disciplines. Following the most contentious decade in over a century, scholarship on the topic of 'contention' is booming. Nonetheless, we still lack a conceptual approach to 'contention' as a general academic term beyond the bounds of the study of 'contentious politics.' What is the meaning of contention? Drawing on a decade of editorial and research work on contention, this article surveys the profound breadth and variety of academic research on the topic, ranging from politics, psychology, and sociology to material culture, criminology, and beyond. We outline the common conceptual thread across these various areas, where 'contention' generally indicates conflictual collective contests concerning competing claims. Keywords: collective action, collective contention, contentious politics, definition of contention, social movements, Contention is everywhere nowadays. The period between 2010 and 2020 has been dubbed 'the most contentious decade' in 120 years, and the current decade may well be set to beat [...]

Research suggests that breastfeeding may reduce child maltreatment risk. Alaska has high rates of both breastfeeding initiation and maltreatment reports to Child Protective Services (CPS). The present study assessed any and exclusive breastfeeding duration and child maltreatment reports to CPS among Alaskan mother-infant dyads, controlling for demographics and shared risk factors. We used a prospective, population-representative dataset linking 2009-2011 Alaska Pregnancy Risk Assessment Monitoring System (PRAMS) data with 2009-2016 Alaska CPS and administrative state data (n = 3,459). Breastfeeding duration was derived from PRAMS breastfeeding questions and categorized as never, < 1 weeks, 1-9 weeks, and [greater than or equal to] 10 weeks. Age at first report of maltreatment to Alaska CPS included physical or sexual abuse, neglect, or mental injury. Hazard ratios and 95% confidence intervals (CI) were calculated using Cox proportional hazard models, adjusting for confounders. There was no increase in risk of maltreatment report among children never breastfed compared to those breastfed for [greater than or equal to] 10 weeks. Risk of maltreatment report during the observation period was 1.7 times as high among children breastfed for < 1 week (CI: 1.06, 2.73), and 1.5 times as high among those breastfed for 1-9 weeks (CI: 1.17, 1.80), compared to those breastfed for [greater than or equal to] 10 weeks. Estimates were attenuated for exclusive breastfeeding. Feeding method did not predict maltreatment reports in this population. Among mothers who initiated breastfeeding, shorter duration was associated with elevated risk of maltreatment reports. Addressing factors that facilitate or prohibit sustained breastfeeding may reduce risk of child maltreatment reports., Author(s): Helena J. Hutchins [sup.1] , Kim G. Harley [sup.1] , Jordyn T. Wallenborn [sup.1] , Barbara Abrams [sup.1] [sup.2] , Rebecca Reno [sup.1] , Jared W. Parrish [sup.3] Author [...]

The MIT Press, 2022 https://doi.org/10.1057/s11369-024-00348-4 In the title of the review appearing in the April 2024 issue the author of the book is referred to as 'Oliver' Blanchard, rather than [...]

: Introduction: Several HIV‐related syndemics have been described among adults. We investigated syndemic vulnerability to hazardous drinking (HD), intimate partner violence (IPV) and household food insecurity (HFIS) in breastfed children born without HIV in urban South Africa. We compared those who were perinatally HIV exposed (CHEU) to those who were not (CHU), under conditions of universal maternal antiretroviral therapy (ART) and breastfeeding. Methods: A prospective cohort of pregnant women living with HIV (WLHIV), and without HIV, were enrolled and followed with their infants for 12 months postpartum (2013–2017). All WLHIV initiated antenatal efavirenz‐based ART. Measurements of growth (∼3 monthly), infectious cause hospitalisation, ambulatory childhood illness (2‐week recall) and neurodevelopment (BSID‐III, measured at ∼12 months’ age) were compared across bio‐social strata using generalised linear regression models, with interaction terms; maternal data included interview‐based measures for HD (AUDIT‐C), IPV (WHO VAW) and HFIS. Results: Among 872 breastfeeding mother‐infant pairs (n = 461 CHEU, n = 411 CHU), WLHIV (vs. HIV negative) reported more unemployment (279/461, 60% vs. 217/411, 53%; p = 0.02), incomplete secondary education (347/461, 75% vs. 227/411, 55%; p < 0.0001), HD (25%, 117/459 vs. 7%, 30/411; p < 0.0001) and IPV (22%, 101/457 vs. 8%, 32/411; p < 0.0001) at enrolment; and HFIS at 12 months (45%, 172/386 vs. 30%, 105/352; p > 0.0001). There were positive interactions between maternal HIV and other characteristics. Compared to food secure CHU, the mean difference (95% CI) in weight‐for‐age Z‐score (WAZ) was 0.06 (−0.14; 0.25) for food insecure CHU; −0.26 (−0.42; −0.10) for food secure CHEU; and −0.43 (−0.61; −0.25), for food insecure CHEU. Results were similar for underweight (WAZ < −2), infectious‐cause hospitalisation, cognitive and motor delay. HIV‐IPV interactions were evident for ambulatory diarrhoea and motor delay. There were HIV‐HD interactions for odds of underweight, stunting, cognitive and motor delay. Compared to HD‐unexposed CHU, the odds ratios (95% CI) of underweight were 2.31 (1.11; 4.82) for HD‐exposed CHU; 3.57 (0.84; 15.13) for HD‐unexposed CHEU and 6.01 (2.22; 16.22) for HD‐exposed CHEU. Conclusions: These data suggest that maternal HIV‐related syndemics may partly drive excess CHEU health risks, highlighting an urgent need for holistic maternal and family care and support alongside ART to optimise the health of CHEU., INTRODUCTION In 2021, the global population of children who are perinatally HIV exposed but HIV negative (CHEU) was almost 16 million, with another one million CHEU born annually [1, 2]. [...]

Restrictive U.S. immigration policies have resulted in increased deportations of unauthorized individuals. This qualitative study examines social service utilization among Latinx immigrant families following the deportation or one or more [...]