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2 results on '"Leavis, Helen L"'

1. Epidemic and nonepidemic multidrug-resistant Enterococcus faecium

Author

Leavis, Helen L., Willems, Rob J.L., Top, Janetta, Spalburg, Emile, Mascini, Ellen M., Fluit, Ad C., Hoepelman, Andy, de Neeling, Albert J., and Bonten, Mark J.M.

Subjects
Drug resistance -- Physiological aspects, Drug resistance -- Genetic aspects, Enterococcal infections -- Genetic aspects, Enterococcal infections -- Development and progression, Enterococcal infections -- Care and treatment
Abstract

The epidemiology of vancomycin-resistant Enterococcus faecium (VREF) in Europe is characterized by a large community reservoir. In contrast, nosocomial outbreaks and infections (without a community reservoir) characterize VREF in the [...]

Published
2003

2. Identification of a novel genomic island specific to hospital-acquired clonal complex 17 Enterococcus faecium isolates

Author

Heikens, Esther, van Schaik, Willem, Leavis, Helen L., Bonten, Marc J.M., and Willems, Rob J.L.

Subjects
Carbohydrate metabolism -- Analysis, Enterococcus -- Genetic aspects, Enterococcus -- Physiological aspects, Polymerase chain reaction -- Usage, Biological sciences
Abstract

The [delta][rho]-Web model, PCR, and dot blotting methods are used to identify anomalous GeCs in the genome of Enterococcus faecium DO, a clonal complex 17 (CC17) E. faecium strains that might contribute towards increased fitness and enhanced survival of CC17 E. faecium. A genomic island identified in CC17 E. faecium tentatively encoding a metabolic pathway involved in carbohydrate transport and metabolism might provide a competitive advantage over the E. faecium microbiota.

Published
2008

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