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1. A de novo TLR7 gain-of-function mutation causing severe monogenic lupus in an infant

Author

Spegarova, Jarmila Stremenova, Sinnappurajar, Praisoody, Julandani, Dalila Al, Navickas, Rokas, Griffin, Helen, Ahuja, Manisha, Grainger, Angela, Livingstone, Katie, Rice, Gillian I., Sutherland, Fraser, Hayes, Corinne, Parke, Simon, Pang, Lewis, Roderick, Marion R., Slatter, Mary, Crow, Yanick, Ramanan, Athimalaipet V., and Hambleton, Sophie

Subjects
Health care industry
Abstract

To the Editor: Childhood-onset systemic lupus erythematosus (cSLE) presents with a more severe phenotype and worse outcomes than adult-onset SLE (1). Genetic factors are understood to have a significant role [...]

Published
2024
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