1. New triarylmethyl derivatives: 'blocking groups' for rotaxanes and polyrotaxanes
- Author
-
Gibson, Harry W., Sang-Hun Lee, Engen, Paul T., Lecavalier, Pierre, Sze, Jean, Ya Xi Shen, and Bheda, Mukesh
- Subjects
Organic compounds -- Synthesis ,Methanol -- Research ,Biological sciences ,Chemistry - Abstract
Five triarylcarbinols were synthesized in good yields through Grignard reactions. Two methods were used to link functionalized spacers to the triarylmethyl moiety. Triarylcarbinols were reduced to triarylmethanes, which were converted to omega,omega,omega-triarylalkanols and then to chloro and iodo derivatives. p-(triarylmethyl)phenols and aniline were synthesized using carbocation chemistry. Alkylation of the former produced alcohol, benzylic bromide and carboxy functionalized derivatives. The resulting functionalized triarylmethyl chlorides could be used as end blocking groups in rotaxanes and polyrotaxanes whose macrocycle contained as much as 42 ring atoms.
- Published
- 1993