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1. Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae

Author

Weinl, Christine, Riehle, Heidemarie, Park, Dongjeong, Stritt, Christine, Beck, Susanne, Huber, Gesine, Wolburg, Hartwig, Olson, Eric N., Seeliger, Mathias W., Adams, Ralf H., and Nordheim, Alfred

Subjects
Neovascularization -- Research -- Physiological aspects, Retinal diseases -- Care and treatment -- Genetic aspects, Phenotype -- Research -- Physiological aspects, Health care industry
Abstract

Retinal vessel homeostasis ensures normal ocular functions. Consequently, retinal hypovascularization and neovascularization, causing a lack and an excess of vessels, respectively, are hallmarks of human retinal pathology. We provide evidence [...]

Published
2013
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