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1. Enantiospecific synthesis of annulated nicotine analogues from D- and L-glutamic acid. Pyridotropanes

Author

Turner, Sean C., Zhai, Hongbin, and Rapoport, Henry

Subjects
Chemistry, Organic -- Research, Acids -- Analysis, Nicotine -- Research, Biological sciences, Chemistry
Abstract

Research has been conducted on the preparation of the conformationally restricted nicotinoid from D- and L-glutamic acid. The pyroglutamic acid derivative coupling with ortho-lithiated 4-chloropyridine is described.

Published
2000

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