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1. Purine enzymes in patients with rheumatoid arthritis treated with methotrexate. (Extended Report)

Author

van Ede, AE, Laan, RFJM, De Abreu, RA, Stegeman, ABJ, and van de Putte, LBA

Subjects
Drug therapy, Physiological aspects, Dosage and administration, Rheumatoid arthritis -- Drug therapy -- Physiological aspects, Methotrexate -- Dosage and administration -- Physiological aspects, Purines -- Physiological aspects
Abstract

Objectives: To study (a) purine metabolism during treatment with methotrexate (MTX) in patients with rheumatoid arthritis (RA) and (b) the relation of purine metabolism with efficacy and toxicity of MTX [...]

Published
2002

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