83 results on '"Balzarini Jan"'
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2. Conservation of antiviral activity and improved selectivity in PMEO-DAPym upon pyrimidine to triazine scaffold hopping
3. NICTABA and UDA, two GlcNAc-binding lectins with unique antiviral activity profiles
4. An emerging understanding of the Janus face of the human microbiome: enhancement versus impairment of cancer therapy
5. Design and synthesis of a new series of cyclopropylamino-linking diarylpyrimidines as HIV non-nucleoside reverse transcriptase inhibitors
6. Synthesis and Anti-HIV Activity of 4-(Naphthalen-1-yl)-1,2,5-thiadiazol-3-hydroxyl Derivatives
7. Exposure of HIV-1 to a combination of two carbohydrate-binding agents markedly delays drug resistance development and selects for virus strains with compromised fitness
8. Carbohydrate-binding agents act as potent trypanocidals that elicit modifications in VSG glycosylation and reduced virulence in Trypanosoma brucei
9. Design, Synthesis, and Biological Evaluation of Novel 3,5-Disubstituted-1,2,6-Thiadiazine-1,1-Dione Derivatives as HIV-1 NNRTIs
10. Inhibition of infection and transmission of HIV-1 and lack of significant impact on the vaginal commensal lactobacilli by carbohydrate-binding agents
11. Dengue virus infection and induction of proinflammatory cytokines in dendritic cells is profoundly inhibited by selective carbohydrate-binding agents (CBAs): 229
12. Synthesis and Anti-HIV Evaluation of Novel 1,2,4-triazole Derivatives as Potential Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors
13. Crucial role of the N-glycans on the viral E-envelope glycoprotein in DC-SIGN-mediated dengue virus infection
14. Inhibition of pyrimidine and purine nucleoside phosphorylases by a 3,5-dichlorobenzoyl-substituted 2-deoxy-d-ribose-1-phosphate derivative
15. Synthesis and biological evaluation of pyrimidine nucleoside monophosphate prodrugs targeted against influenza virus
16. Combination of Antiretroviral Drugs as Microbicides
17. Microwave Assisted Synthesis, Characterization of Some New Isatin and Thiophene Derivatives as Cytotoxic and Chemopreventive Agents
18. Selective inhibition of Human Immunodeficiency Virus type 1 (HIV-1) by a novel family of tricyclic nucleosides
19. The cytostatic activity of NUC-3073, a phosphoramidate prodrug of 5-fluoro-2′-deoxyuridine, is independent of activation by thymidine kinase and insensitive to degradation by phosphorolytic enzymes
20. Expression analysis of the nucleocytoplasmic lectin ‘Orysata’ from rice in Pichia pastoris
21. Synergistic in vitro anti-HIV type 1 activity of tenofovir with carbohydrate-binding agents (CBAs)
22. Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models
23. Nicotinic Acid Benzylidene/Phenyl-Ethylidene Hydrazides: Synthesis, Antimicrobial Evaluation and QSAR Studies
24. The rare HIV-1 gp41 mutations 43T and 50V elevate enfuvirtide resistance levels of common enfuvirtide resistance mutations that did not impact susceptibility to sifuvirtide
25. Identification of a N-linked Glycan on HIV-1 gp120 that is Indispensable for Viral Entry: 20
26. In vitro synergistic activity against CCR5-tropic HIV-1 with combinations of potential candidate microbicide molecules HHA, KRV2110 and enfuvirtide (T20)
27. FV100 as a new approach for the possible treatment of varicella-zoster virus infection
28. Acute cytotoxicity of arabinofuranosyl nucleoside analogs is not dependent on mitochondrial DNA
29. Capture and transmission of HIV-1 by the C-type lectin L-SIGN (DC-SIGNR) is inhibited by carbohydrate-binding agents and polyanions
30. Novel 9-Arylpurines, as Selective Inhibitors of In Vitro Enterovirus Replication: 180
31. Cytostatic and Antiviral Activity Evaluations of Hydroxamic Derivatives of Some Non-steroidal Anti-inflammatory Drugs
32. Discovery of 8-methoxypyrazino[1,2-a]indole as a New Potent Antiproliferative Agent Against Human Leukemia K562 Cells. A Structure-Activity Relationship Study
33. The cytostatic activity of pyrimidine nucleosides is strongly modulated by Mycoplasma hyorhinis infection: Implications for cancer therapy
34. Novel Lipophilic Hydroxyurea Derivatives: Synthesis, Cytostatic and Antiviral Activity Evaluations
35. Design, Synthesis and Evaluation of Novel Anti-VZV BCNAs: 33
36. Enzyme-triggered CycloSal-Pronucleotides: 27
37. Increased mitochondrial DNA copy-number in CEM cells resistant to delayed toxicity of 2′,3′-dideoxycytidine
38. Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus
39. Targeting platelet-derived endothelial cell growth factor/thymidine phosphorylase for cancer therapy
40. Efficient conversion of tetrapeptide-based TSAO prodrugs to the parent drug by dipeptidyl-peptidase IV (DPPIV/CD26)
41. Plant lectins are potent inhibitors of coronaviruses by interfering with two targets in the viral replication cycle
42. Chemical Stability and Intracellular Metabolism of 1-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]-5-Azacytosine: 145
43. Properties of Aminoacid Esters Linked to Cyclo Sal-Pronucleotides: 110
44. Design, Synthesis, and Biological Evaluation of Novel Anti-VZV Agents: 108
45. Design and Synthesis of Novel Anti-HCMV Agents: Modifications to the Bicyclic Pyrimidine Base: 106
46. In Vivo Antiviral Activity of 1-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]-5-Azacytosine and its Cyclic Form: 17
47. Synthesis and Antiviral Activity of 1-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]-5-Azacytosine and its Ester Prodrugs: 16
48. Pronounced in vitro and in vivo antiretroviral activity of 5-substituted 2,4-diamino-6-[2-(phosphonomethoxy)ethoxy] pyrimidines
49. Inhibition of feline (FIPV) and human (SARS) coronavirus by semisynthetic derivatives of glycopeptide antibiotics
50. Therapeutic strategies towards HIV-1 infection in macrophages
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