1. Dual-channel discrimination of two lethal chemical warfare agents using an ESIPT-ICT-based fluorescent probe.
- Author
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Sun M, Pei Z, Chen J, Zhang S, Cen J, Gao F, and Meng WQ
- Subjects
- Humans, Pyridines chemistry, Thiazoles chemistry, Fluorescent Dyes chemistry, Fluorescent Dyes chemical synthesis, Chemical Warfare Agents analysis, Spectrometry, Fluorescence, Cyanides analysis
- Abstract
Among all kinds of chemical warfare agents, only cyanide and nerve agents can cause massive mortality at low concentrations. In this work, a dual-channel fluorescent probe CWAs-Thia capable of detecting cyanide and nerve agents is presented. The two reactive recognition units, pyridine and the thiazole-2-carbonyl group, of the probe for cyanide and nerve agents, respectively, produced red and blue fluorescent responses, respectively, which were attributed to excited-state intramolecular proton transfer and intramolecular charge transfer. CWAs-Thia is the first probe that can selectively recognize cyanide and nerve agent. And it has proven to be effective in visualizing cyanide and nerve agents in living cells., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier B.V. All rights reserved.) more...
- Published
- 2025
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