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Brain tumors, often referred to as intracranial tumors, are abnormal tissue masses that arise from rapidly multiplying cells. During medical imaging, it is essential to separate brain tumors from healthy tissue. The goal of this paper is to improve the accuracy of separating tumorous regions from healthy tissues in medical imaging, specifically for brain tumors in MRI images which is difficult in the field of medical image analysis. In our research work, we propose IC-Net (Inverted-C), a novel semantic segmentation architecture that combines elements from various models to provide effective and precise results. The architecture includes Multi-Attention (MA) blocks, Feature Concatenation Networks (FCN), Attention-blocks which performs crucial tasks in improving brain tumor segmentation. MA-block aggregates multi-attention features to adapt to different tumor sizes and shapes. Attention-block is focusing on key regions, resulting in more effective segmentation in complex images. FCN-block captures diverse features, making the model more robust to various characteristics of brain tumor images. Our proposed architecture is used to accelerate the training process and also to address the challenges posed by the diverse nature of brain tumor images, ultimately leads to potentially improved segmentation performance. IC-Net significantly outperforms the typical U-Net architecture and other contemporary effective segmentation techniques. On the BraTS 2020 dataset, our IC-Net design obtained notable outcomes in Accuracy, Loss, Specificity, Sensitivity as 99.65, 0.0159, 99.44, 99.86 and DSC (core, whole, and enhancing tumors as 0.998717, 0.888930, 0.866183) respectively., (© 2024. The Author(s).)

COVID-19 is a life threatening disease which has a enormous global impact. As the cause of the disease is a novel coronavirus whose gene information is unknown, drugs and vaccines are yet to be found. For the present situation, disease spread analysis and prediction with the help of mathematical and data driven model will be of great help to initiate prevention and control action, namely lockdown and qurantine. There are various mathematical and machine-learning models proposed for analyzing the spread and prediction. Each model has its own limitations and advantages for a particluar scenario. This article reviews the state-of-the art mathematical models for COVID-19, including compartment models, statistical models and machine learning models to provide more insight, so that an appropriate model can be well adopted for the disease spread analysis. Furthermore, accurate diagnose of COVID-19 is another essential process to identify the infected person and control further spreading. As the spreading is fast, there is a need for quick auotomated diagnosis mechanism to handle large population. Deep-learning and machine-learning based diagnostic mechanism will be more appropriate for this purpose. In this aspect, a comprehensive review on the deep learning models for the diagnosis of the disease is also provided in this article.