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12 results on '"El-Gokha, Ahmed"'

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1. Synthesis, biological evaluation and molecular modelling of 3-Formyl-6-isopropylchromone derived thiosemicarbazones as α-glucosidase inhibitors.

2. Cytotoxic Potential of Novel Quinoline Derivative: 11-(1,4-Bisaminopropylpiperazinyl)5-methyl-5H-indolo[2,3-b]quinoline against Different Cancer Cell Lines via Activation and Deactivation of the Expression of Some Proteins.

3. Design and cytotoxic evaluation via apoptotic and antiproliferative activity for novel 11(4-aminophenylamino)neocryptolepine on hepatocellular and colorectal cancer cells.

4. Synthesis and evaluation of novel xanthene-based thiazoles as potential antidiabetic agents.

5. Synthesis, Biological Evaluation, and In Silico Studies of Novel Coumarin-Based 4 H ,5 H -pyrano[3,2- c ]chromenes as Potent β-Glucuronidase and Carbonic Anhydrase Inhibitors.

6. Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors.

7. Discovery and Evaluation of Enantiopure 9 H -pyrimido[4,5- b ]indoles as Nanomolar GSK-3β Inhibitors with Improved Metabolic Stability.

8. Structural Optimization of a Pyridinylimidazole Scaffold: Shifting the Selectivity from p38α Mitogen-Activated Protein Kinase to c-Jun N-Terminal Kinase 3.

9. Tri- and Tetrasubstituted Pyridinylimidazoles as Covalent Inhibitors of c-Jun N-Terminal Kinase 3.

10. Fluorescence polarization-based assays for detecting compounds binding to inactive c-Jun N-terminal kinase 3 and p38α mitogen-activated protein kinase.

11. An optimized and versatile synthesis to pyridinylimidazole-type p38α mitogen activated protein kinase inhibitors.

12. Synthesis and in vitro testing of antimalarial activity of non-natural-type neocryptolepines: structure–activity relationship study of 2,11- and 9,11-disubstituted 6-methylindolo[2,3-b]quinolines.

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