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252 results on '"Eskitis Institute for Drug Discovery"'

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2. Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders.

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3. Factors related to sleep disturbances for individuals with Parkinson's disease: a regional perspective.

4. 8-Aminoquinolines with an Aminoxyalkyl Side Chain Exert in vitro Dual-Stage Antiplasmodial Activity.

6. Cell Swelling Induced by the Antimalarial KAE609 (Cipargamin) and Other PfATP4-Associated Antimalarials.

7. Comparison of serum levels of IL-6, IL-8, TGF-β and TNF-α in coronary artery diseases, stable angina and participants with normal coronary artery.

8. Sulfotransferase 1A3/4 copy number variation is associated with neurodegenerative disease.

9. Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway.

10. N400 and emotional word processing in Parkinson's disease.

12. Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors.

13. Reply: Heterozygous PINK1 p.G411S in rapid eye movement sleep behaviour disorder.

14. Actinomycete Metabolome Induction/Suppression with N-Acetylglucosamine.

15. USP9X deubiquitylating enzyme maintains RAPTOR protein levels, mTORC1 signalling and proliferation in neural progenitors.

16. An integrative systematic framework helps to reconstruct skeletal evolution of glass sponges (Porifera, Hexactinellida).

17. Role of the VPS35 D620N mutation in Parkinson's disease.

18. Probing function and structure of trehalose-6-phosphate phosphatases from pathogenic organisms suggests distinct molecular groupings.

19. Multidrug-resistant cancer cells and cancer stem cells hijack cellular systems to circumvent systemic therapies, can natural products reverse this?

20. Chronoinflammaging in Alzheimer; A systematic review on the roles of toll like receptor 2.

21. Synthesis, biological characterisation and structure activity relationships of aromatic bisamidines active against Plasmodium falciparum.

22. Discovery of new nanomolar inhibitors of GPa: Extension of 2-oxo-1,2-dihydropyridinyl-3-yl amide-based GPa inhibitors.

23. Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity.

24. Potential of marine natural products against drug-resistant fungal, viral, and parasitic infections.

25. SC83288 is a clinical development candidate for the treatment of severe malaria.

26. Synthesis and biological evaluation of a new class of benzothiazines as neuroprotective agents.

27. Polyoxygenated Cyclohexenes and Other Constituents of Cleistochlamys kirkii Leaves.

28. Peroxisomal protein PEX13 functions in selective autophagy.

29. A Patient-Specific Stem Cell Model to Investigate the Neurological Phenotype Observed in Ataxia-Telangiectasia.

30. Heterozygous PINK1 p.G411S increases risk of Parkinson's disease via a dominant-negative mechanism.

31. 6α-Acetoxyanopterine: A Novel Structure Class of Mitotic Inhibitor Disrupting Microtubule Dynamics in Prostate Cancer Cells.

32. Merosesquiterpene Congeners from the Australian Sponge Hyrtios digitatus as Potential Drug Leads for Atherosclerosis Disease.

33. P-glycoprotein-mediated chemoresistance is reversed by carbonic anhydrase XII inhibitors.

34. Meeting the Challenge: Using Cytological Profiling to Discover Chemical Probes from Traditional Chinese Medicines against Parkinson's Disease.

35. In vitro and ex vivo activity of an Azadirachta indica A.Juss. seed kernel extract on early sporogonic development of Plasmodium in comparison with azadirachtin A, its most abundant constituent.

37. Library of diversely substituted 2-(quinolin-4-yl)imidazolines delivers novel non-cytotoxic antitubercular leads.

38. Olfactory ensheathing cells but not fibroblasts reduce the duration of autonomic dysreflexia in spinal cord injured rats.

39. Targeted knockdown of DJ-1 induces multiple myeloma cell death via KLF6 upregulation.

40. Biological characterization of chemically diverse compounds targeting the Plasmodium falciparum coenzyme A synthesis pathway.

41. Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides.

42. Increased Serum Levels of IL-17A and IL-23 Are Associated with Decreased Vitamin D3 and Increased Pain in Osteoarthritis.

43. Semi-synthesis and NMR spectral assignments of flavonoid and chalcone derivatives.

44. Evaluation of NLRC4, NLRP1, and NLRP3, as Components of Inflammasomes, in Chronic Hepatitis B Virus-Infected Patients.

45. Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles.

46. Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.

47. Mitochondrial changes and oxidative stress in a mouse model of Zellweger syndrome neuropathogenesis.

48. Evaluation of fermentation conditions triggering increased antibacterial activity from a near-shore marine intertidal environment-associated Streptomyces species.

49. Expression of the thioredoxin system in an in vivo-like cancer cell environment upon auranofin treatment.

50. Transmission blocking effects of neem (Azadirachta indica) seed kernel limonoids on Plasmodium berghei early sporogonic development.