1. Use of cardiovascular medicines in newly treated type 2 diabetes patients: A retrospective cohort study in general practice.
- Author
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Grimes RT, Ensor J, Bennett K, and Henman MC
- Subjects
- Administrative Claims, Healthcare, Adult, Age Factors, Aged, Aged, 80 and over, Antihypertensive Agents therapeutic use, Aspirin therapeutic use, Cardiovascular Diseases diagnosis, Cardiovascular Diseases etiology, Diabetes Mellitus, Type 2 complications, Diabetes Mellitus, Type 2 diagnosis, Drug Utilization Review, Female, Guideline Adherence, Humans, Ireland, Male, Middle Aged, Platelet Aggregation Inhibitors therapeutic use, Practice Guidelines as Topic, Retrospective Studies, Risk Factors, Time Factors, Treatment Outcome, Vasodilator Agents therapeutic use, Cardiovascular Agents therapeutic use, Cardiovascular Diseases prevention & control, Diabetes Mellitus, Type 2 drug therapy, General Practice, Hydroxymethylglutaryl-CoA Reductase Inhibitors therapeutic use, Hypoglycemic Agents therapeutic use, Practice Patterns, Physicians' standards
- Abstract
Aims: To describe the drug utilisation patterns of aspirin, antihypertensives, vasodilators, and statins in a cohort of newly treated type 2 diabetes subjects previously unexposed to CVD agents., Methods: A population-based retrospective cohort study was conducted using a national pharmacy claims database of newly treated type 2 diabetes subjects aged 40 years or older. Data on the use of aspirin, antihypertensives, vasodilators, and statins 1 year after antidiabetic agent initiation were analysed. Poisson regression with a robust error variance was used to estimate adjusted relative risk (RRadj) and 95% CIs between socio-demographic and treatment factors on CVD agent use., Results: Over a 2-year period (2008-2009), 6093 subjects were identified. One year after antidiabetic agent initiation, 82% of the study population received at least one CVD agent, with 54% receiving aspirin, 64% receiving antihypertensives, 6% vasodilators, and 62% receiving statins. Subjects aged 40-49 years were significantly less likely than those aged 60-69 years to receive CVD agents (RRadj 0.83, 95% CI 0.80-0.87). Over 40% of subjects received antihypertensives without aspirin and statins, while 30% of subjects on statins did not receive aspirin., Conclusions: Substantial CVD agent utilisation was noted 1 year after antidiabetic agent initiation. Being aged younger than 60-69 years was associated with decreased utilisation of CVD agents., (Copyright © 2015 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2016
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