1. In vitro inhibitory activities of sugarcane extract on avian Eimeria sporozoites.
- Author
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Daneshmand A, Young P, Campbell B, Kheravii SK, Sharma NK, Afshari R, Dias DA, Flavel M, Kitchen B, and Wu SB
- Subjects
- Animals, Chickens, Plant Extracts pharmacology, Sporozoites, Coccidiosis drug therapy, Coccidiosis veterinary, Eimeria, Poultry Diseases drug therapy, Saccharum
- Abstract
The current in vitro study aimed to investigate the effects of a processed sugarcane extract on the viability of avian Eimeria sporozoites. Treatments were applied to hatched sporozoites: 1) without additives (no-treatment control); 2) with ethanol; 3) with salinomycin; 4) with Polygain™. All treatments were incubated in RPMI media containing live sporozoites at 37 °C for 14 h and then the number of viable sporozoites were counted. Compared to the no-treatment control, Polygain™ decreased (P < 0.001) the counts of E. maxima, E. acervulina, E. bruneti, and E. mitis sporozoites to a level similar to salinomycin (P > 0.05). In conclusion, Polygain™ could be a potential candidate as an anticoccidial agent., (Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.)
- Published
- 2021
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