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This study aimed to quantify U.S. jurisdiction-level costs related to the COVID-19 Vaccination Program by estimating the per-dose-administered cost during December 20, 2020-May 31, 2021, from a combined federal and local government perspective. Costs were limited to vaccine purchase, administration (including operations and wastage), and local redistribution by jurisdictions. Data were collected through publicly available sources, published literature, and a survey of 62 jurisdictions (38 responded). A total of 284.6 million doses of COVID-19 vaccine were distributed to jurisdictions during the study period, of which 284.2 million doses were administered, and 0.4 million doses were wasted. The estimated cost per-dose-administered among the 38 jurisdictions that responded to study survey was $57.45 and imputed cost across all jurisdictions was $63.11. The findings on jurisdiction-level cost per-dose-administered and vaccination cost during the initial period of U.S. COVID-19 Vaccination Program, when demand exceeded supply, may be considered in future pandemic preparedness planning., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024. Published by Elsevier Ltd.)

Background: Aloe vera is a plant traditionally used for medicinal purposes. It is also used as a cosmetic. Aloe vera gel/extract/juice is used in hair care, moisturizing, cleansing, and thickening agent in formulations. Aloe vera gel is rarely used for burns, wounds, infections, and gastric diseases., Objectives: To study the patents filed recently and understand the trend in the application of Aloe vera for therapeutic purposes., Methods: This patent review focuses on granted patents during the year 2013 to 2020. The patents were analyzed, and their therapeutic use was studied to assess the recent trends in Aloe vera formulations., Results: Most of the patents studied in this article are based on skincare products. Out of those, the maximum patents are on moisturizing compositions. Most of the patents are found in US jurisdiction and a few in Europe and China. As there are certain restrictions on patenting inventions related to composition and natural products in various jurisdictions, patents are only found in a few jurisdictions., Conclusion: The trend of the use of Aloe vera is still towards cosmetic products. Also, Aloe vera is used in oral care composition, deodorant compositions, anti-inflammatory composition, vitamin compositions, antibiotic compositions, etc., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)

Feeding wild birds is a common and popular human-wildlife interaction throughout the world. However, controversy exists over the benefits and costs to the birds and humans involved. This bibliometric study documents wild bird feeding policies around the globe and examines environmental and socio-cultural factors which may influence the position adopted by these policies. We located 412 policies from 237 different countries, territories or dependencies (jurisdictions); 58.7% of jurisdictions had no information available online regarding wild bird feeding policy. Generalized Linear Modelling revealed that colder minimum ambient temperatures were associated with more pro-feeding policy settings. An index of controversy was calculated for each jurisdiction; most (77.6%) had no controversy. This study highlights the significant variation in policy settings for wild bird feeding across jurisdictions and controversy in almost a quarter of jurisdictions. Recommendations are made for the development of clear, consistent and readily available policy advice on this globally popular human-wildlife interaction., (Copyright © 2018 Elsevier B.V. All rights reserved.)

This study aims to provide a quantitative basis for the precision emission reduction of land-based total nitrogen (TN) pollutants in Qingdao, China. The total maximum allocated load (TMAL) of TN pollutants within jurisdictions in Qingdao was calculated by using a 3D hydrodynamic-water quality model and a linear programming model. The TMAL includes emission TMAL, point-source and nonpoint source TMAL, TMAL removed by municipal sewage treatment system (MSTS), and soil-retained and water-retained TMAL, which were calculated after the division of source units, establishment of the land-based TN load matrix, simulation of the concentration response matrix, setting of a dissolved inorganic nitrogen (DIN) concentration control standard in the Qingdao coastal area, and calculation of TMAL. In the reliability analysis, a concentration under TMAL was considered to indicate satisfactory water quality criteria (relative standard deviation = 17%, Kappa = 0.55). The results showed that the emission TMAL density of nitrogen pollutants in source units was 1.8 ton/km 2 /a. Nonpoint and point source-produced TMAL densities were 17.0 ton/km 2 /a and 5.2 ton/km 2 /a, respectively. MSTS-removed TMAL density was 12.2 ton/km 2 /a. Soil- and water-retained TMAL were 4.0 ton/km 2 /a and 0.7 ton/km 2 /a, respectively. The summed F (D) ∗ proportions of 10 districts were, in descending order, Huangdao (22%), Laoshan (21%), Jimo (18%), Shibei (13%), Licang (7%), Pingdu (7%), Jiaozhou (4%), Shinan (3%), Laixi (3%) and Chengyan (2%)., (Copyright © 2018 Elsevier B.V. All rights reserved.)

This paper investigates how the concepts of clinical specialisation and evidence influence the jurisdictional power of doctors, nurses and therapists involved in stroke care in Sweden, England and Poland. How stroke care has become a distinct specialism across Europe and the role that evidence has played in this development are critically analysed. Five qualitative case studies were undertaken across the three countries, consisting of 119 semi-structured interviews with a range of healthcare workers. The informants were purposively selected and their perspectives of evidence-based practice (EBP) within stroke care were explored. The data were analysed through thematic content analysis. The two key themes that emerged from the data were the health professionals' degrees of EBP and specialisation. The results illustrate how the two concepts of clinical specialisation and evidence are interrelated and work together to influence the different professions' degree of professional jurisdiction. It is concluded that doctors' professional dominance gives them full jurisdiction in stroke care and that nurses' and therapists' degrees of jurisdiction is dependent on their ability to specialise., (Copyright © 2016 Elsevier Ltd. All rights reserved.)

Background: The Emergency Department (ED) is the portal of entry to the health care system for a large percentage of patients. This is especially true for victims and perpetrators of interpersonal violence. Frequently, law enforcement personnel (LEP) accompany patients to the ED or seek access to patients during their ED stay or subsequent hospitalization. The time-sensitive nature of both emergency care and criminal investigation motivates both health care personnel and LEP, and can lead to potential conflicts of interest regarding access to patients in the ED., Objectives: We hope to examine the relationship among patients, providers, and LEP in the ED, and the potential impact these interactions have on patient care. This article presents a review of the relevant literature and policy consideration as well as provides guidance on the development of such policies for EDs., Discussion: Hospitals, EDs, and trauma resuscitation rooms are highly regulated environments, but LEP largely fall outside the ethical and institutional guidelines of health care institutions. Many potential areas of conflict exist when LEP are present in the ED that can have detrimental effects on patient care, provider liability, and LEP efficacy. Patients' perceptions of collaboration between ED personnel and LEP can compromise emergency patient care., Conclusion: There is a need for hospital policies to govern interactions among patients, emergency health care providers, and LEP in the ED., (Copyright © 2015 Elsevier Inc. All rights reserved.)

The imposition of the insanity defense is a complicated psycho-legal scenario. Globally, definitions of insanity differ from country to country. In a multitude of cases, a determination of insanity at the time of a criminal act means the offender will not be considered responsible for his or her action(s). In many jurisdictions, concerns have been raised that the insanity defense has been used to mitigate punishment, usually after a particularly heinous crime. In this review, the authors use three cases - Frendak, Phenis, and Breivik to demonstrate how the imposition of the insanity defense has been used for legal purposes in the past and present. In an effort to give more background to each of the above-mentioned cases, the writers have provided some details to aid comprehension. The authors offer recommendations for the ethical forensic evaluator unburdened by partisan allegiance and invested in the search for truth. This review article relies on peer-reviewed articles available from PubMed, Meharry Online Library, and legal dictionaries. We also cross-referenced reputable news sources to ensure the validity of the facts we present.