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Introduction: The National Administration of Traditional Chinese Medicine of the People's Republic of China (NATCM) and the State Administration of Traditional Chinese medicine (TCM) advocated a combination therapy of TCM and anti-viral drugs for novel coronavirus pneumonia (NCP) to improve the efficacy of clinical treatment., Methods: Forty-six patients diagnosed with NCP were sequentially divided into intent-to-treat population: the experimental group (combination of FuXi-Tiandi-Wuxing Decoction and anti-viral drugs; n = 23) and the control group (anti-viral drugs only) (n = 23). The two groups were compared in terms of duration of fever, cough symptom score, fatigue, appetite, dyspnea, out-of-bed activities, chest computer tomography (CT) recovery, virological clearance, average length of hospital stay, and clinical effective rate of drug. After 6 days of observation, patients from the control group were divided into as-treated population: experimental subgroup (n = 14) to obtain clinical benefit and control subgroup (n = 9)., Results: There was a significant improvement in the duration of fever (1.087 ± 0.288 vs 4.304 ± 2.490), cough (0.437 ± 0.589 vs 2.435 ± 0.662; P < 0.05), chest CT evaluation (82.6% vs 43.4%; P < 0.05), and virological clearance (60.8% vs 8.7%; P < 0.05) in patients of the experimental group compared with patients in the control group. Further observation in as-treated population reported that cough (0.742 ± 0.463 vs 1.862 ± 0.347; P < 0.05) and fatigue (78.5% vs 33.3%; P < 0.05) were significantly relieved after adding FuXi-Tiandi-Wuxing Decoction to the existing treatment., Conclusion: An early treatment with combination therapy of FuXi-Tiandi-Wuxing Decoction and anti-viral drugs significantly relieves the clinical symptoms of NCP, shows improvement in chest CT scan, improves virological clearance, shortens average length of hospital stay, and reduces the risk of severe illness. The effect of FuXi-Tiandi-Wuxing Decoction in NCP may be clinically important and require further consideration., Competing Interests: The authors do not have any conflicts of interest., (© 2023 Published by Elsevier GmbH.)

The past decade has witnessed tremendous research efforts devoted to two-dimensional (2D) materials and great progress made in both their fundamental studies and technique development. 2D light-emitting materials such as transition-metal dichalcogenides (TMDs) and phosphorene are receiving particular attention as a result of their intriguing electronic, optical and optoelectronic properties. The ability to tune their layer numbers, engineer their dielectric environment, form alloys, create van der Waals heterostructures, etc. provides further means to modulate their properties which have led to a number of interesting luminescence features and potential applications in lighting, imaging and sensing. As the map of 2D materials has expanded over the past few years, 2D organic and organic-inorganic hybrid materials, such as 2D polymers, metal-organic frameworks (MOFs), and organic-inorganic hybrid perovskites, have also emerged with merits of low cost, chemical versatility and solution processibility. Importantly, the wide tunability of their functional properties is enabled by the rational design and controlled modification of their compositions and structures at the molecular level. Herein, we present a critical review of 2D light-emitting materials by categorizing them into three main groups, namely 2D inorganic light-emitting materials, 2D organic light-emitting materials, and 2D organic-inorganic hybrid light-emitting materials. Within each group, we will describe their preparation methods and discuss their structural and chemical properties. Significant emphasis will be placed on strategies that can tune their luminescence properties, and their potential applications in various fields. Finally, we will summarize by stating the current challenges and future opportunities in the development of 2D light-emitting materials.