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1. Establishing the validity of different susceptibility testing methods to evaluate the in vitro activity of amoxicillin-clavulanate against Escherichia coli.

Author

María DA, María-Isabel M, María-Carmen C, Álvaro P, Jorge C, Luis MM, Francesc M, Jordi V, Adriana O, Jesús O, and Rafael C

Subjects
Amoxicillin-Potassium Clavulanate Combination pharmacology, Anti-Bacterial Agents pharmacology, Escherichia coli drug effects, Microbial Sensitivity Tests methods
Abstract

Amoxicillin-clavulanate MICs of 160 Escherichia coli isolates with characterized resistance mechanisms were obtained by 2 MIC gradient strip brands, 3 automated systems, and reference ISO microdilution method using EUCAST (fixed 2μg/mL clavulanate) and CLSI (2:1 ratio) criteria. Discrepancies, mainly obtained with gradient strips, lead to an essential agreement range of 76.2-92.5., (Copyright © 2016 Elsevier Inc. All rights reserved.)

Published
2016
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