1. Symptoms in patients with primary hyperparathyroidism: muscle weakness or sleepiness.
- Author
-
Walker RP, Paloyan E, and Gopalsami C
- Subjects
- Aged, Disorders of Excessive Somnolence etiology, Female, Humans, Hyperparathyroidism complications, Male, Middle Aged, Muscle Weakness etiology, Prospective Studies, Wakefulness, Disorders of Excessive Somnolence surgery, Hyperparathyroidism surgery, Muscle Weakness surgery, Parathyroidectomy
- Abstract
Objective: To evaluate the effects of parathyroidectomy on the nonspecific symptoms associated with primary hyperparathyroidism, with an emphasis on distinguishing sleepiness from muscle weakness., Methods: We conducted a prospective cohort study of consecutive patients presenting for parathyroidectomy for the treatment of primary hyperparathyroidism. Twenty-three patients underwent assessment preoperatively and postoperatively. The Functional Outcomes of Sleep Questionnaire (FOSQ), the Epworth Sleepiness Scale (ESS), and a questionnaire of disease-specific symptoms were administered preoperatively, 2 weeks postoperatively, and 4 to 6 months postoperatively. The FOSQ assesses how sleepiness alters daytime performance, and the ESS reflects the degree of daytime sleepiness., Results: All 23 patients achieved normocalcemia postoperatively. Although no significant changes were found in the overall scores for the FOSQ and ESS after parathyroidectomy, there was a significant decline in the overall mean incidence of disease-specific symptoms postoperatively (P
- Published
- 2004
- Full Text
- View/download PDF