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Frailty is characterised by a loss of function across several domains but is not an inevitable aspect of ageing and can be reversed with intervention. Determining those who are more likely to become frail before physical deficits become manifest will allow earlier intervention. One promising indicator of the potential for frailty is allostatic load, a physiological status associated with prolonged stress that is, characterised by multisystem dysfunction. Previous research has sought to understand the links between allostatic load and frailty, but has not yet explored whether allostatic load may be a predictive factor at younger ages and-if so-at what age it may be predictive. The present study sets out establish whether allostatic load can be used as a predictive indicator of frailty. Using the English Longitudinal Survey on Ageing (ELSA) data with an anticipated sample of 1500 people between 50 and 89 years old, time series analysis will determine if, and at what age, allostatic load may be predictive of pre-frailty and frailty. The findings of these analyses may be supportive of early identification of frailty by establishing an age at which a diagnostic test for allostatic load may prove a critical indicator for future frailty., (© 2024 The Author(s). Stress and Health published by John Wiley & Sons Ltd.)

The phrase 'in it together' has been used liberally since the outbreak of COVID-19, but the extent that frontline workers felt 'in it together' is not well understood. Here, we consider the factors that built (or eroded) solidarity while working through the pandemic, and how frontline workers navigated their lives through periods of disconnection. Semi-structured interviews with 21 frontline workers, across all sectors, were conducted in the United Kingdom and Ireland. The qualitative data were analysed systematically using reflexive thematic analysis. The three themes identified in the data were: (1) Solidarity as central to frontline experiences; (2) Leadership as absent, shallow and divisive: highlighting 'us-them' distinctions and (3) The rise of 'us' and 'we' among colleagues. Our research offers insights into how frontline workers make sense of their experiences of solidarity and discordance during the first year of the COVID-19 pandemic, with relevance for government and organizational policy-makers shaping future conditions for frontline workers., (© 2022 The Authors. British Journal of Social Psychology published by John Wiley & Sons Ltd on behalf of British Psychological Society.)

Throughout the Covid-19 pandemic, frontline workers have carried out essential roles to keep society going, while the public have been called to minimise the infection rate to limit the burden on frontline workers. In this sense, navigating Covid-19 has necessitated interdependence between frontline workers and key stakeholder groups (such as their colleagues, organisations, their government, and the public). Reports suggest that frontline workers have perceived varying degrees of solidarity with others throughout the pandemic, yet the influence of perceived solidarity on psychological welfare has received limited empirical or theoretical attention. The aim of the present study was to test the importance of perceived solidarity (or solidarity appraisal ) by assessing the relationship between perceptions of solidarity and psychological welfare in frontline workers - across all sectors - during Covid-19, and explore the role of a potential mechanism (i.e., meaning in life) for explaining this relationship. To assess this proposed model, we used cross-sectional and longitudinal data from a project tracking a cohort of frontline workers in the UK and Ireland since March 2020. Participants were surveyed at baseline (T1), at six months (T2), and 12 months (T3). At T3, participants ( N  ​= ​414) reported their perceived solidarity (with colleagues, organisations, government, and public) along with a range of psychological welfare measures. Overall, frontline workers' levels of meaning in life dropped significantly over time. Lower levels of perceived solidarity were predictive of poorer wellbeing, and higher anxiety, burnout, post-traumatic stress symptoms, and somatic stress symptoms, and these relationships were mediated by the presence of meaning in life. These findings suggest that perceived solidarity with interdependent social groups may imbue life with meaning, which can in turn have a positive influence on psychological welfare in chronic and cumulatively stressful occupational settings., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2022 The Author(s).)

The purpose of this article is to offer an alternative, more nuanced analysis of the labelling of frontline workers as heroes than originally proposed. Here, we argue that the hero narrative in itself need not be problematic, but highlight a number of wider factors that have led to the initial rise (and subsequent fall) in support for labelling frontline workers as heroes. Through our related work, we have gathered similar stories from frontline workers where they feel betrayed, let down or otherwise short-changed by the hero label, and we have sought to make sense of this through understanding more about how the hero label is used rather than what it means. In this article, we propose a way forward where there is greater discussion around the hero label in this context where individuals can be heroes but still struggle, still fail and still feel vulnerable, and where heroism is viewed as a state of interdependence between heroic actor and the wider group. It is true that heroes can inspire, lead, guide and build morale and camaraderie, but collective responsibility is held with us all. We can draw hope and energy from our heroes, but we must dig deep and be proactive, particularly in the face of adversity. In doing so, we support the heroes to lead from the front and ensure that even though we cannot physically help; we are not making their situation worse., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.)

Objective: Frontline workers have shown extraordinary resilience and sustained efforts since the outbreak of COVID-19. The present study used semi-structured interviews with 38 frontline workers in the UK and Ireland to explore the psychological impact of working through COVID-19., Design: The qualitative data were analysed systematically using thematic analysis., Results: Four themes were interpreted: 1) ) " I've stopped turning the telly on. I've had to because the news was making me ill": An ecosystem of influence; 2) "Dead, dead, dead": The emotional and psychological toll: 3) " It's shone a light on what we're failing on as well" : Injustices, hierarchies and heroes: and 4) " I definitely think COVID happened for a reason to stop us in our tracks and to slow us down": Unexpected positives., Conclusion: This research offers insights into how frontline workers make sense of their experiences during periods of enormous societal and occupational stress. The learnings generated have relevance for government and organisational policy-makers who have opportunities to shape future conditions for frontline workers.

The context of Covid-19 has offered an unusual cultural landscape for examining how workers view their own position relative to others, and how individuals respond to prolonged exposure to workplace stress across different sectors and cultures. Through our recent work tracking the well-being of frontline workers in the UK and Ireland (the CV19 Heroes project), we have uncovered additional psychological factors that have not been accounted for in previous models of occupational stress or burnout. In recent months, frontline workers have worked to protect the community from the threat of SARS-CoV-2 and, simultaneously, have evaluated their perceptions of collective efforts of others as either congruent or incongruent with collective goals (e.g., lowered mortality and morbidity): we call this novel aspect solidarity appraisal . These frontline workers have been hailed as heroes, which we argue has led to the creation of an implicit psychological contract ( the hero contract ) between frontline workers and the public. Here, the heroes are willing to "go above and beyond" for the greater good, with the expectation that we (the public) do our part by adhering to public health guidelines. Where frontline workers perceive incongruence between the words and actions of others in working toward collective goals this drives negative affect and subsequent burnout. In this perspective article, we evaluate the cultural context of the pandemic in the UK and Ireland and suggest important socio-cultural factors that contribute to perceptions of solidarity, and how this may relate to burnout and worker welfare during and beyond the pandemic context., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Sumner and Kinsella.)

The coronavirus pandemic has necessitated extraordinary human resilience in order to preserve and prolong life and social order. Risks to health and even life are being confronted by workers in health and social care, as well as those in roles previously never defined as "frontline," such as individuals working in community supply chain sectors. The strategy adopted by the United Kingdom (UK) government in facing the challenges of the pandemic was markedly different from other countries. The present study set out to examine what variables were associated with resilience, burnout, and wellbeing in all sectors of frontline workers, and whether or not these differed between the UK and Republic of Ireland (RoI). Individuals were eligible if they were a frontline worker (in health and social care, community supply chain, or other emergency services) in the UK or RoI during the pandemic. Part of a larger, longitudinal study, the participants completed an online survey to assess various aspects of their daily and working lives, along with their attitudes toward their government's handling of the crisis, and measurement of psychological variables associated with heroism (altruism, meaning in life, and resilient coping). A total of 1,305 participants ( N = 869, 66.6% from the UK) provided sufficient data for analysis. UK-based workers reported lower wellbeing than the RoI-based participants. In multivariate models, both psychological and pandemic-related variables were associated with levels of resilience, burnout, and wellbeing in these workers, but which pandemic-related variables were associated with outcomes differed depending on the country. The judgment of lower timeliness in their government's response to the pandemic appeared to be a key driver of each outcome for the UK-based frontline workers. These findings provide initial evidence that the different strategies adopted by each country may be associated with the overall wellbeing of frontline workers, with higher detriment observed in the UK. The judgment of the relatively slow response of the UK government to instigate their pandemic measures appears to be associated with lower resilience, higher burnout, and lower wellbeing in frontline workers in the UK., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Sumner and Kinsella.)

Background: Arts on prescription interventions have grown in number in recent years with a corresponding evidence base in support. Despite the growth and presence of these interventions, there have been no evaluations to date as to what factors predict patient success within these referral schemes., Methods: Using the largest cohort of patient data to date in the field (N = 1297), we set out to understand those factors that are associated with attendance, programme engagement and wellbeing change of patients. Factors associated with these outcomes were assessed using three binary logistic regression models., Results: Baseline wellbeing was associated with each outcome, with higher baseline wellbeing being associated with attendance and engagement, and lower baseline wellbeing associated with positive wellbeing change. Additionally, deprivation was associated with attendance, with those from the median deprivation quintile being more likely to attend., Conclusions: The role of baseline wellbeing in each outcome of these analyses is the most critical associative factor. Whilst those that are lower in wellbeing have more to gain from these interventions, they are also less likely to attend or engage, meaning they may need additional support in commencing these types of social prescribing interventions., (© The Author(s) 2019. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)

Unemployment has been associated with poorer health, but few studies have examined the biological mechanisms that confer these health decrements. Further, no studies to date have examined differences across employment groups to consider whether employment (in whatever means) is preferential in terms of health. The present study utilised secondary data from Understanding Society: The Household Longitudinal Survey during the aftermath of the recent global recession. Two markers of peripheral inflammation: C-reactive protein (CRP) and fibrinogen were assessed across employment groups (unemployed; permanent, temporary, and self-employed), controlling for individual, socio-demographic and health variables to give greater context to our understanding of how employment status influences health. After controlling for relevant confounds, unemployment was associated with higher levels of fibrinogen but not CRP. Subsequent analyses of employment subgroup revealed the temporary employed have similar levels of fibrinogen to the unemployed, and may therefore be at a similar health disadvantage. The findings confirm that unemployment is associated with increases in one marker of peripheral inflammation, but that this health protection is not conferred to those in precarious employment., (Copyright © 2019 Elsevier Inc. All rights reserved.)

Background : This paper draws on a longitudinal study exploring the outcomes of an arts referral programme in General Practice in the South West of England since 2009. It focuses on the qualitative responses of the patient cohort Methods : Using qualitative methods and thematic analysis, this paper explores and considers the responses from n  = 1297 participants who provided feedback from an open-ended questionnaire on self-reported benefits of the arts referral programme. Results : Participant reactions demonstrate that the programme provided a range of personal and social benefits rarely considered or explored in comparative studies. The analysis suggests participants were able to self-manage aspects of their health-related conditions, and were able to make progress towards a better physical and/or mental health. Conclusions : The evidence suggests that arts-based referral programmes, have a range of benefits for participants that may not have been fully appreciated. The consequences on self-management requires further investigation.

In recent decades there has been a dramatic increase in the amount of research focused on purpose in life, demonstrating a host of benefits that emerge for individuals committed to a purpose. As with other constructs in the positive youth development framework, there is a paucity of work investigating how experiences of marginalization impact the development of this psychological asset among adolescents. To catalyze research on this front, we draw attention to potential opportunities and obstacles associated with experiences of marginalization and how they might affect an adolescent developing a purpose in life. Like García Coll and colleagues' (1996) integrative model, our perspective includes sociocultural factors (e.g., social position, adaptive culture), an emphasis on intragroup variability, and discussion of potentially promoting and inhibiting aspects of marginalization. Following a description of existing research on purpose development during adolescence, we discuss how experiences of marginalization could contour the development of self-integrative, strong, and articulated purpose among adolescents. To conclude, specific considerations for future research are outlined, including how existing definitions of and tools for measuring purpose can be adapted to produce a scientific literature that values and includes the normative purpose development of adolescents who experience marginalization. (PsycINFO Database Record, ((c) 2018 APA, all rights reserved).)

Background: Arts for health interventions are an accepted option for medical management of mental wellbeing in health care. Updated findings are presented from a prospective longitudinal follow-up (observational) design study of an arts on referral programme in UK general practice, over a 7-year period (2009-2016)., Methods: Primary care process and mental wellbeing outcomes were investigated, including progress through the intervention, changes in mental wellbeing, and factors associated with those outcomes. A total of n =1297 patients were referred to an eight or 10-week intervention over a period from 2009 to 2016. Patient sociodemographic information was recorded at baseline, and patient progress (e.g. attendance) assessed throughout the intervention., Results: Of all referrals, 51.7% completed their course of prescribed art (the intervention). Of those that attended, 74.7% engaged with the intervention as rated by the artists leading the courses. A significant increase in wellbeing was observed from pre- to post-intervention (t = -19.29, df =523, P < 0.001, two-tailed) for those that completed and/or engaged. A sub sample (N =103) of these referrals self-reported multi-morbidities. These multiple health care service users were majority completers (79.6%), and were rated as having engaged (81.0%). This group also had a significant increase in well-being, although this was smaller than for the group as a whole (t = -7.38, df =68, P < 0.001)., Conclusion: Findings confirm that art interventions can be effective in the promotion of well-being for those that complete, including those referred with multi-morbidity, with significant changes in wellbeing evident across the intervention periods.

Objective: Unemployment is a type of chronic stressor that impacts human health. The reasons for how the stress of unemployment affect health is still a matter of discussion. One of the pathways from chronic stress to ill health is mediated by cortisol, and so we set out to compile extant data on how its secretion is affected by unemployment., Design: A systematic literature search was conducted to establish the cortisol dysregulatory effects of this stressor., Main Outcome Measures: Only studies that specifically examined the effects of unemployment on cortisol excretion, and were written in English were included., Results: Ten reports were obtained and synthesised to determine the severity and complexity of the effect of unemployment on cortisol secretion. The resulting combined evidence is mixed in terms of degree or dynamic of relationship., Conclusions: The differences between the cumulate findings of the studies can be understood in the context of the lack of both standardised methodology and an absence of consensus on unemployment definition. We propose existing methodologies may be strengthened by acknowledging and accounting for the individual characteristics that may be relevant to the stress experience of unemployment.

Previous research has investigated the endocrinological consequences of unemployment as a likely pathway behind chronic stress and negative health outcomes. Despite these early attempts at delineating the neuroendocrine consequences of the chronic stress experienced by the unemployed, identifying a consistent and stable effect has remained elusive. Here we sought to strengthen existing knowledge into the effect of the stress of employment status on cortisol by improving on the methodological weaknesses of earlier studies and extend this line of enquiry by measuring the steroid hormone Dehydroepiandrosterone-Sulfate (DHEAS). Saliva samples were collected from unemployed and employed participants at four time points across two days. As expected, unemployed people reported higher stress, lower social support and lower self-esteem. Unexpectedly, the unemployed showed lower overall cortisol output, a likely consequence of a higher cortisol awakening response (CAR) in the employed. However, they also had a higher DHEA output across the day, albeit the diurnal pattern across the day was more dysregulated compared to that seen in those employed with a blunted response evident in the evening; the cortisol:DHEAS ratio was also lower in the unemployed group. Further, these hormone differences were correlated with self-esteem and stress. Taken together these results suggest that the relationship between employment status and endocrine responses is far more complicated than previously thought. We have shown for the first time that unemployed people have a lower CAR, but also show a blunted DHEA response relative to those employed and we suggest that this may be a feature of chronic stress exposure or perhaps dependent on the prevailing socio-economic context., (Copyright © 2016 Elsevier Ltd. All rights reserved.)

People tend to overestimate the steepness of slopes, especially when they appraise the effort necessary to ascend them as greater. Recent studies, however, suggest the way individuals perceive visual stimuli may rely heavily on their personal motivations. In four studies (N = 517), purpose in life was tested as a motivational framework influencing how appraised effort relates to slope perception. Studies 1 and 2 found the amount of effort participants appraised necessary to ascend several virtual slopes was related to greater overestimation of their steepness. Yet, this relationship was attenuated by purpose assessed both as a disposition and experimental manipulation. Studies 3 and 4 replicated these findings using actual hills, again showing links between the amount of effort thought required to ascend them and their perceived angle were diminished by greater purpose. The discussion addresses implications of purpose as a broad motivational framework that shapes how individuals see their environment., (© 2015 by the Society for Personality and Social Psychology, Inc.)

Comments on the original article "Life is pretty meaningful," by S. J. Heintzelman and L. A. King (see record 2014-03265-001). Heintzelman and King condense descriptive data from numerous studies to conclude that individuals tend to see life as meaningful, because average scores on the meaning and purpose in life assessments fall above the midpoint. However, in so doing, they make two contentious assumptions. The first is the expectation that scale midpoints actually reflect an average score on that construct. However, one should not interpret this metric to suggest that people generally live meaningful lives without great caution and consideration of the second assumption: the conflation of purpose and meaning in life. In response, the current authors address this second assumption and the need to develop better questions and measures for both meaning and purpose., ((PsycINFO Database Record (c) 2015 APA, all rights reserved).)

Emerging demographic trends signal that White Americans will soon relinquish their majority status. As Whites' acclimation to an increasingly diverse society is poised to figure prominently in their adjustment, identifying sources of greater comfort with diversity is important. Three studies (N = 519) revealed evidence that purpose in life bolsters comfort with ethnic diversity among White adults. Specifically, dispositional purpose was positively related to diversity attitudes and attenuated feelings of threat resulting from viewing demographic projections of greater diversity. In addition, when primed experimentally, purpose attenuated participants' preferences for living in an ethnically homogeneous-White city, relative to a more diverse city when shown maps displaying ethno-demographic information. These effects persisted after controlling for positive affect and perceived connections to ethnic out-groups, suggesting the robust influence of purpose. Potential benefits of situating purpose as a unique resource for navigating an increasingly diverse society are discussed., (© 2014 by the Society for Personality and Social Psychology, Inc.)

Objectives: Neuromodulation of the immune system has been proposed to be influenced by hemispheric lateralisation (HL). The present study tested whether HL predicted CD4+ levels, statistically controlling for confounders., Methods: Employing two assessments of HL, 68 human immunodeficiency virus (HIV)-1+ patients were followed prospectively. Numerous exclusion criteria and confounder assessments were employed (e.g. age/medication)., Results: Left HL significantly positively predicted CD4+ levels at follow-up, and this was qualified by medication (HAART) status: only in HAART-naïve patients did HL predict CD4 levels. Furthermore, HL significantly predicted whether patients had clinically significantly high/low CD4+ counts., Conclusions: Using a more rigorous methodology than a previous study, the present work partly corroborated the theory of HL influences on immunity, extended it to HIV immunity and identified a possible moderator: HAART medication. Implications for future research and treatments are provided., (© 2013 S. Karger AG, Basel.)

Past studies examined relationships between hemispheric lateralisation (HL) and immune system functioning. However, there has been no up-dated systematic review of this research area. This article reviews relevant published studies, evaluates study quality and effect sizes. Eleven studies were selected: three revealing a relationship between weaker left hemisphere function and poorer immune function, three describing a relationship between weaker right hemisphere function and stronger immune functioning, and five describing both relationships. Mean effect-size of the studies was r=0.536 (range 0.280-0.866). Collectively, studies point at left-HL and stronger immunity relationships. Limitations, mechanisms and clinical implications are discussed., (Copyright © 2011 Elsevier B.V. All rights reserved.)

Nilanjana Dasgupta's (this issue) stereotype inoculation model (SIM) helps explain why what feels like a free choice to pursue one life path over another "is often constrained by subtle cues in achievement environments that signal who naturally belongs there and is most likely to succeed and who else is a dubious fit" (p. 231). She posits that seeing others like themselves in successful roles inoculates women against negative stereotypes that impede their success and persistence in specific achievement contexts.As is true of classic theoretical positions (see Nagel, 1961), Dasgupta presents postulates from which she deduces a specific set of hypotheses, and she reviews the relevant empirical/observational data in support of them. It is precisely what this area of research has long needed-moving beyond demonstrations of identity threats to a theory about their underlying causes, conditions, and interventions. This proposal leads her to four broad predictions, the first of which is the primary focus of our comment.