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Objective: To study the nutrition habits among Chinese-Korean children and adolescents in Yanbian Autonomous Prefecture, Jilin, China., Methods: Data were obtained from the Chinese National Survey on Students' Constitution and Health in 1995, 2000, 2005, and 2010 for Chinese-Korean children and adolescents aged 7-18 years. The number of the subjects included was 4789, 4704, 5875, and 5315, respectively., Results: The rate of the occurrence of stunting showed a declining trend from 1995 to 2010 (for boys: urban, 6.3%; rural, 12.7% in 1995 and 3.5% for both in 2010. For girls: urban, 7.8%; rural, 13.4% in 1995 and 4.2% and 5.5%, respectively, in 2010). Although the ratio of wasting did not show significant differences between the urban and rural children and adolescents in 1995, 2000, 2005, and 2010 respectively, the ratio of occurrence of overweight or obesity increased (for boys: urban, 7.3% and 1.3% in 1995, 17.6% and 12.9% in 2010; rural, 7.0% and 1.3% in 1995, 14.6% and 12.8% in 2010, respectively. For girls: urban, 8.1% and 1.0% in 1995, 17.3% and 8.6% in 2010; rural 5.7% and 0.7% in 1995, 16.4% and 7.4% in 2010, respectively)., Conclusion: The ratio of malnutrition in children and adolescents in Chinese-Korean areas declined from 1995 to 2010, and the distinction in malnutrition between the urban and rural areas was negligible in 2010. Further, the ratio of overweight and obesity increased over this period., (Copyright © 2016 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved.)

Background: Obesity in adolescents and children has become a global public health problem and lots of factors influence the status of obesity and overweight. The present study aims to compare the health-related factors which could influence the obesity in Chinese children and adolescents in three different groups which including the local developed city group, rural-to-urban migrants group and immigrants origin areas group., Methods: We conducted a cross-sectional study consisted of 2457 children and adolescents aged 7-10 years old including 914 rural-to-urban migrants subjects, 795 local Shanghai subjects and 748 from immigrant origin areas. Physique measurements and self-reported information on health-related factors, such as physical activities, dietary habits, socio-economic factors such as family income, sleep habits, etc. were collected by questionnaire. SPSS16.0 was used in the analysis., Results: Mean level of body height, body weight and sitting height were different among the three groups, local youth group was higher in all the indexes than the other two groups. Grip for both hands were higher in local group also, while the heart rate was lowest in rural-to-ruban migrants group. The mean BMI in three groups showed significant difference, highest for local group. Higher SBP level was found in city and rural-to-urban migrants group also. However, no difference of DBP between groups was detected. The distribution of pre-hypertension and hypertension in three groups were significantly different and the distribution of overweight and obesity between genders in all three groups were different. The prevalence of overweight was 19.04% in rural-to-urban migrants group (19.92% for male and 17.64% for female), 28.21% for city group (35.64% for male and 20.72% for female); while no overweight or obesity subjects were found in immigrant origin areas group in this study. When compared the overweight and obesity prevalence between city group and rural-to-urban migrants, we found the overweight was more common in the local youth group. Univariable Logistic regression analysis and multivariable analysis results suggested that the more rice intake, higher family income and SBP higher than 140 mmHg were risk factors to obesity for rural-to-ruban migrants, while good dietary habits (no TV watching during meals) was preventive factor to obesity and SBP higher than 120 mmHg and unsocial factor were associated with obesity for rural-to-urban migrants., Conclusions: Our study revealed the prevalence of overweight and obesity in developed city children and adolescents and rural-to-urban migrants were relatively high, especially more common in local population and male gender. Lifestyle, dietary and psychological factors offered important contribution in increasing or decreasing the risk of obesity.

Objective: To assess the prevalence of malnutrition among children and adolescents in Xizang (Tibet)., Methods: We analyzed data from the Chinese National Survey on Students' Constitution and Health for the years 1995, 2000, 2005, and 2010 pertaining to Tibetan children and adolescents in lase (Lhasa), aged 7-18 years old. Numbers of survey subjects for these years were: 2393, 2754, 2397, and 2643, respectively., Results: Our results indicated that the rate of occurrence of stunting in Tibet has evidenced a gradual decline: for boys, from 26.8% in 2000 to 9.3% in 2010; and for girls, from 25.8% in 2000 to 10.8% in 2010. In general, the wasting rate for both boys and girls in Tibet has gradually decreased over time: for boys, from 17.7% in 1995 to 4.6% in 2005; and for girls from 12.5% in 1995 to 2.3% in 2005. The stunting rates of boys aged 7-13 years old and of girls aged 7-11 years old were 67.5% and 53.1%, respectively, while these rates for boys aged 14-18 years old and girls aged 12-18 years old were 32.5% and 46.9%, respectively., Conclusion: Stunting and wasting rates of Tibetan children and adolescents indicate a gradual declining trend over time. The stunting rates of both boys and girls during early puberty were significantly higher than those during late puberty., (Copyright © 2014 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved.)

Aim: Dysregulation of the activity of the disintegrin/metalloproteinase ADAM10 could contribute to the development of atherosclerosis. Although a number of genetic studies have focused on the association of ADAM10 gene polymorphisms with susceptibility to diseases, no genetic association studies of ADAM10 gene variability with atherosclerotic cerebral infarction (ACI) have been conducted. The aim of this study was to analyze the potential association between ADAM10 promoter polymorphisms and ACI., Methods: The associations between rs653765 and rs514049 polymorphisms of the ADAM10 promoter and the possible risk of ACI were assessed among 347 patients with ACI and 299 matched healthy individuals in a case-control study., Results: Overall, there was a significant difference in the genotypes frequencies of rs653765 (P = 0.04) between the ACI and control subjects. In addition, the rs653765 mutated allele of ADAM10 was significantly associated with increased ADAM10 expression in patients with ACI (P = 0.032). In contrast, the allele frequency of rs514049 was not statistically associated with ACI, and the rs514049 variant A > C did not affect the expression of ADAM10 either., Conclusion: Our findings indicate a positive association between the rs653765 polymorphism of ADAM10 and ACI, as well as a negative result for rs514049. In addition, a significant increase in ADAM10 expression was observed in patients with ACI carrying the rs653765 C > T mutation. This new knowledge about ADAM10 might be clinically important and confirm a role for ADAM10 in the pathophysiology of ACI, with potentially important therapeutic implications., (© 2013 The Authors. CNS Neuroscience & Therapeutics published by John Wiley & Sons Ltd.)

Objectives: The purpose of this study is to define and clarify the causes of differences in physique between urban students and rural students in China., Methods: Subjects are 2,524 students (male, 838; female, 1686) who entered K University in Shanghai in September, 2001. The data used in this study is based upon K university's Yearly Health Check Record and Students' Family Condition Record. Correlation analysis, analysis of variance (ANOVA) and analysis of covariance (ANCOVA) were applied to analyze the relationships between physique and gross family income, family income per capita, latitude, air temperature, precipitation or altitude., Results: Urban students' height and weight are significantly greater than rural students' in both males and females. Both male students and female students are significantly taller and heavier in accordance with per capita increases in students' family income. The height and weight of male and female students whose parents are peasant farmers are least. With regard to the relationship between physique and urban-rural factors, the F value decreases clearly when family income per capita is taken as a covariate, while the F values slightly decrease also when factors of latitude etc. are taken as covariates. The main cause of differing family income is occupational difference between urban areas and rural ones., Conclusion: Students born in urban areas are taller and heavier than those born in rural areas. The main cause of these differences is family income per capita. The main cause of variations in family income is the income difference in occupations.