1. [Rectal diffuse large B cell lymphoma appearing after immunosuppression for ulcerative colitis. Report of one case].
- Author
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Quera R, Flores L, Simian D, Kronberg U, Vial MT, de Guevara DL, and García-Rodríguez MJ
- Subjects
- Antineoplastic Combined Chemotherapy Protocols therapeutic use, Azathioprine adverse effects, Biopsy, Cyclophosphamide administration & dosage, Doxorubicin administration & dosage, Gastrointestinal Agents adverse effects, Humans, Infliximab adverse effects, Lymphoma, Large B-Cell, Diffuse diagnostic imaging, Male, Middle Aged, Positron Emission Tomography Computed Tomography, Prednisone administration & dosage, Rectal Neoplasms diagnostic imaging, Rituximab administration & dosage, Vincristine administration & dosage, Colitis, Ulcerative drug therapy, Immunosuppressive Agents adverse effects, Lymphoma, Large B-Cell, Diffuse etiology, Lymphoma, Large B-Cell, Diffuse pathology, Rectal Neoplasms etiology, Rectal Neoplasms pathology
- Abstract
Primary colorectal lymphoma is a rare form of presentation of gastrointestinal tract lymphomas. Inflammatory bowel disease and its treatment are risk factors for its development. We report a 47-year-old male patient with Ulcerative Colitis of two years of evolution, treated initially with azathioprine and later on with infliximab. Due to a relapse in symptoms after the second dose of infliximab, a new coloncoscopy was performed showing a rectal ulcerative lesion, corresponding to a large cell Non-Hodgkin's Lymphoma. The patient was successfully treated with RCHOP chemotherapy (Rituximab cyclophosphamide doxorubicin vincristine prednisone). He is currently in disease remission.
- Published
- 2017
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