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1. Health based animal and meat safety cooperative communities

Author: Vågsholm, I., Belluco, S., Bonardi, S., Hansen, Fredrik, Elias, T., Roasto, M., Gomes-Neves, E., Antunovic, B., Kautto, A. H., Alban, L., Blagojevic, B., Vågsholm, I., Belluco, S., Bonardi, S., Hansen, Fredrik, Elias, T., Roasto, M., Gomes-Neves, E., Antunovic, B., Kautto, A. H., Alban, L., and Blagojevic, B.
Abstract: The purposes of meat inspection have been formulated for more than 100 years as (a) protecting health of consumers, (b) maintain the reputation of the meats in home and export markets, and (c) detecting communicable diseases of animals before they have spread beyond easy control. Today, one would add to protect animal welfare, clarify that protecting consumer health includes both chemical and biological hazards, and add food fraud to the issues of reputation. To transform the scientific knowledge into modern meat safety assurance systems (MSAS), the risk managers need to understand the social capital in the meat value chain to align the behaviors of farmers, food business operators and competent authorities with technical knowledge. The meat value chain could be perceived as a commons – a material or immaterial property held jointly by the members of a community, whom may govern access to and use of the property through social structures, traditions, and/or formal rules i.e. social capital. The social capital and food safety culture amongst farmers and food business operators is a key driver for successful meat safety while information asymmetry increases risks for a tragedy of commons scenario. Ostrom's core design principles for stable commons could inform the design of MSASs. Tools for reducing the information asymmetry and building trust and social capital between all stakeholders within the meat value chain include the food safety culture, food chain information, use of health epidemiological indicators, sensors and block chains, industry/private standards, and the applying system approach from farm to fork.
Published: 2023
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2. Mapping ways of detecting and handling antimicrobial residues in pigs and pig meat in- and outside Europe

Author: Alban, L., Antunović, B., Belous, M., Bonardi, S., García-Gimeno, R. M., Jenson, I., Kautto, A. H., Majewski, M., Oorburg, D., Sakaridis, I., Sirbu, A., Vieira-Pinto, M., Vågsholm, I., Bērziņš, A., Petersen, J. V., Alban, L., Antunović, B., Belous, M., Bonardi, S., García-Gimeno, R. M., Jenson, I., Kautto, A. H., Majewski, M., Oorburg, D., Sakaridis, I., Sirbu, A., Vieira-Pinto, M., Vågsholm, I., Bērziņš, A., and Petersen, J. V.
Abstract: Withdrawal periods after antimicrobial treatment have been defined as preventing in meat the presence of residues above the maximum residue limits (MRLs). However, errors can lead to residues above MRLs. The RIBMINS COST Action network investigated the question of how detection and handling are applied in different countries, and what the best practices may be, when balancing consumer safety with EU policy on minimising food waste. Two questionnaires were developed focusing on pigs, targeting the competent authority and the food business operator. The survey was undertaken in spring 2022 and resulted in 78 answers representing 27 countries. The results showed that most countries operate their system as a kind of monitoring, where the tested carcass is not detained. We suggest two best practice models where Model A (monitoring) could reflect small abattoirs placing meat on the national market, whereas Model B (surveillance) could reflect abattoirs also trading and exporting. In Model A, detection of a residue above the MRL is interpreted in the same way as a process hygiene criterion, requires on-farm inspection to correct mistakes only, and therefore no retention of tested carcases. In Model B, detection of a residue above the MRL is interpreted as a food safety criterion, requires on-farm inspection and the tested carcass is retained to avoid expensive recalls in case residues are found.
Published: 2023

3. Mapping ways of detecting and handling antimicrobial residues in pigs and pig meat in- and outside Europe

Author: Alban, L., Antunović, B., Belous, M., Bonardi, S., García-Gimeno, R. M., Jenson, I., Kautto, A. H., Majewski, M., Oorburg, D., Sakaridis, I., Sirbu, A., Vieira-Pinto, M., Vågsholm, I., Bērziņš, A., Petersen, J. V., Alban, L., Antunović, B., Belous, M., Bonardi, S., García-Gimeno, R. M., Jenson, I., Kautto, A. H., Majewski, M., Oorburg, D., Sakaridis, I., Sirbu, A., Vieira-Pinto, M., Vågsholm, I., Bērziņš, A., and Petersen, J. V.
Abstract: Withdrawal periods after antimicrobial treatment have been defined as preventing in meat the presence of residues above the maximum residue limits (MRLs). However, errors can lead to residues above MRLs. The RIBMINS COST Action network investigated the question of how detection and handling are applied in different countries, and what the best practices may be, when balancing consumer safety with EU policy on minimising food waste. Two questionnaires were developed focusing on pigs, targeting the competent authority and the food business operator. The survey was undertaken in spring 2022 and resulted in 78 answers representing 27 countries. The results showed that most countries operate their system as a kind of monitoring, where the tested carcass is not detained. We suggest two best practice models where Model A (monitoring) could reflect small abattoirs placing meat on the national market, whereas Model B (surveillance) could reflect abattoirs also trading and exporting. In Model A, detection of a residue above the MRL is interpreted in the same way as a process hygiene criterion, requires on-farm inspection to correct mistakes only, and therefore no retention of tested carcases. In Model B, detection of a residue above the MRL is interpreted as a food safety criterion, requires on-farm inspection and the tested carcass is retained to avoid expensive recalls in case residues are found.
Published: 2023

4. Review of transmission routes of 24 infectious diseases preventable by biosecurity measures and comparison of the implementation of these measures in pig herds in six European countries

Author: Filippitzi, M. E., Kruse, Amanda Brinch, Postma, M., Sarrazin, S., Maes, D., Alban, L., Nielsen, Liza Rosenbaum, Dewulf, J., Filippitzi, M. E., Kruse, Amanda Brinch, Postma, M., Sarrazin, S., Maes, D., Alban, L., Nielsen, Liza Rosenbaum, and Dewulf, J.
Abstract: This study aimed to review the transmission routes of important infectious pig diseases and to translate these into biosecurity measures preventing or reducing the transmission between and within pig herds. Furthermore, it aimed to identify the level of implementation of these measures in different European countries and discuss the observed variations to identify potentials for improvement. First, a literature review was performed to show which direct and indirect transmission routes of 24 infectious pig diseases can be prevented through different biosecurity measures. Second, a quantitative analysis was performed using the Biocheck.UGent™, a risk-based scoring system to evaluate biosecurity in pig herds, to obtain an insight into the implementation of these biosecurity measures. The database contained farm-specific biosecurity data from 574 pig farms in Belgium, Denmark, France, Germany, the Netherlands and Sweden, entered between January 2014 and January 2016. Third, a qualitative analysis based on a review of literature and other relevant information resources was performed for every subcategory of internal and external biosecurity in the Biocheck.UGent™ questionnaire. The quantitative analysis indicated that at the level of internal, external and overall biosecurity, Denmark had a significantly distinct profile with higher external biosecurity scores and less variation than the rest of the countries. This is likely due to a widely used specific pathogen-free (SPF) system with extensive focus on biosecurity since 1971 in Denmark. However, the observed pattern may also be attributed to differences in data collection methods. The qualitative analysis identified differences in applied policies, legislation, disease status, pig farm density, farming culture and habits between countries that can be used for shaping country-specific biosecurity advice to attain improved prevention and control of important pig diseases in European pig farms., This study aimed to review the transmission routes of important infectious pig diseases and to translate these into biosecurity measures preventing or reducing the transmission between and within pig herds. Furthermore, it aimed to identify the level of implementation of these measures in different European countries and discuss the observed variations to identify potentials for improvement. First, a literature review was performed to show which direct and indirect transmission routes of 24 infectious pig diseases can be prevented through different biosecurity measures. Second, a quantitative analysis was performed using the Biocheck.UGent™, a risk‐based scoring system to evaluate biosecurity in pig herds, to obtain an insight into the implementation of these biosecurity measures. The database contained farm‐specific biosecurity data from 574 pig farms in Belgium, Denmark, France, Germany, the Netherlands and Sweden, entered between January 2014 and January 2016. Third, a qualitative analysis based on a review of literature and other relevant information resources was performed for every subcategory of internal and external biosecurity in the Biocheck.UGent™ questionnaire. The quantitative analysis indicated that at the level of internal, external and overall biosecurity, Denmark had a significantly distinct profile with higher external biosecurity scores and less variation than the rest of the countries. This is likely due to a widely used specific pathogen‐free (SPF) system with extensive focus on biosecurity since 1971 in Denmark. However, the observed pattern may also be attributed to differences in data collection methods. The qualitative analysis identified differences in applied policies, legislation, disease status, pig farm density, farming culture and habits between countries that can be used for shaping country‐specific biosecurity advice to attain improved prevention and control of important pig diseases in European pig farms.
Published: 2018

5. A prospective international observational prevalence study on prone positioning of ARDS patients: the APRONET (ARDS Prone Position Network) study

Author: Guã©rin, C, Beuret, P, Constantin, J, Bellani, G, Garcia-Olivares, P, Roca, O, Meertens, J, Maia, P, Becher, T, Peterson, J, Larsson, A, Gurjar, M, Hajjej, Z, Kovari, F, Assiri, A, Mainas, E, Hasan, M, Morocho-Tutillo, D, Baboi, L, Chrã©tien, J, Franã§ois, G, Ayzac, L, Chen, L, Brochard, L, Mercat, A, Sellami, W, Ferjani, M, Al Bshabshe, A, Almekhlafi, G, Mandourah, Y, Rai, V, Marzida, M, Corcoles Gonzalez, V, Sanchez Iniesta, R, Garcia, P, Garcia-Montesinos de la PeÃ±a, M, Garcia Herrera, A, Garcia-de-Acilu, M, Masclans Enviz, J, Mancebo, J, Heili, S, Artigas Raventos, A, Blanch Torra, L, Roche-Campo, F, Rialp, G, Forteza, C, Berrazueta, A, Martinez, E, Penuelas, O, Jara-Rubio, R, Mallat, J, Thevenin, D, Zogheib, E, Levrat, A, Porot, V, Bedock, B, Grech, L, Plantefeve, G, Badie, J, Besch, G, Pili-Floury, S, Guisset, O, Robine, A, Prat, G, Doise, J, Badet, M, Thouret, J, Just, B, Perbet, S, Lautrette, A, Souweine, B, Chabanne, R, Danguy des DÃ©serts, M, Rigaud, J, Marchalot, A, Bele, N, Beague, S, Hours, S, Marque, S, Durand, M, Payen, J, Stoclin, A, Gaffinel, A, Winer, A, Chudeau, N, Tirot, P, Thyrault, M, Paulet, R, Aubrun, F, Guerin, C, Floccard, B, Rimmele, T, Argaud, L, Hernu, R, Crozon Clauzel, J, Wey, P, Bourdin, G, Pommier, C, Cueuille, N, de Varax, N, Marchi, E, Papazian, L, Jochmans, S, Monchi, M, Jaber, S, de Jong, A, Moulaire, V, Capron, M, Jarrige, L, Barberet, G, Lakhal, K, Rozec, B, Dellamonica, J, Robert, A, Bernardin, G, Danin, P, Raucoules, M, Runge, I, Foucrier, A, Hamada, S, Tesniere, A, Fromentin, M, Samama, C, Mira, J, Diehl, J, Mekontso Dessap, A, Arbelot, C, Demoule, A, Roche, A, Similowski, T, Ricard, J, Gaudry, S, Dreyfuss, D, de Montmolin, E, da Silva, D, Verdiere, B, Ardisson, F, Lemiale, V, Azoulay, E, Bruel, C, Tiercelet, K, Fartoukh, M, Voiriot, G, Hoffmann, C, Leclerc, T, Thille, A, Robert, R, Beduneau, G, Beuzelin, M, Tamion, F, Morel, J, Tremblay, A, Molliex, S, Amal, J, Meaudre, E, Goutorbe, P, Laffon, M, Gros, A, Nica, A, Barjon, G, Dahyot-Fizelier, C, Imzi, N, Gally, J, Real, N, Sauneuf, B, Souloy, X, Girbes, A, Tuinman, P, Schultz, M, Winters, T, Mijzen, L, Roekaerts, P, Vermeijden, W, Beishuizen, A, Trof, R, Corsten, S, Kesecioglu, J, Dieperink, W, Pickers, P, Roovers, N, Duque, M, Rua, F, Pereira de Figueired, A, Ramos, A, Fragoso, E, Azevedo, P, Gouveia, J, Costa E. Silva, Z, Silva, G, Chaves, S, Nobrega, J, Lopes, L, Valerio, B, Araujo, A, de Freitas, P, Bouw, M, Melao, M, Granja, C, Marcal, P, Fernandes, A, Joao, G, Maia, D, Spadaro, S, Volta, C, Citerio, G, Mauri, T, Alban, L, Pesenti, A, Mistraletti, G, Formenti, P, Tommasino, C, Tardini, F, Fumagalli, R, Colombo, R, Fossali, T, Catena, E, Todeschini, M, Gnesin, P, Cracchiolo, A, Palma, D, Tetamo, R, Albiero, D, Costantini, E, Raimondi, F, Coppadoro, A, Vascotto, E, Lusenti, F, Schã¤dler, D, Weiler, N, Karagiannidis, C, Petersson, J, Konrad, D, Kawati, R, Wessbergh, J, Valtysson, J, Rockstroh, M, Borgstrom, S, Larsson, N, Thunberg, J, Camsooksai, J, Briggs, N, Cuesta, J, Anwar, S, Oâ€TMBrien, B, Barberis, L, Sturman, J, Karatzas, S, Piza, P, Sottiaux, T, Adam, J, Gawda, R, Gawor, M, Alqdah, M, Cohen, D, Baker, A, Ã‘amendys-Silva, S, Garcia-Guillen, F, Morocho Tutillo, D, Jibaja Vega, M, Zakalik, G, Pagella, G, Marengo, J, GuÃ©rin, C., Beuret, P., Constantin, J. M., Bellani, G., Garcia-Olivares, P., Roca, O., Meertens, J. H., Maia, P. Azevedo, Becher, T., Peterson, J., Larsson, A., Gurjar, M., Hajjej, Z., Kovari, F., Assiri, A. H., Mainas, E., Hasan, M. S., Morocho-Tutillo, D. R., Baboi, L., ChrÃ©tien, J. M., FranÃ§ois, G., Ayzac, L., Chen, L., Brochard, L., Mercat, A., Hajjej, Zied, Sellami, Walid, Ferjani, M., Gurjar, Mohan, Assiri, Amer, Al Bshabshe, Ali, Almekhlafi, Ghaleb, Mandourah, Yasser, Hasan, Mohd Shahnaz, Rai, Vineya, Marzida, M., Corcoles Gonzalez, Virgilio, Sanchez Iniesta, Rafael, Garcia, Pablo, Garcia-Montesinos de la PeÃ±a, Manuel, Garcia Herrera, Adriana, Roca, Oriol, Garcia-de-Acilu, Marina, Masclans Enviz, Joan Ramon, Mancebo, Jordi, Heili, Sarah, Artigas Raventos, Antonio, Blanch Torra, LluÃs, Roche-Campo, Ferran, Rialp, Gemma, Forteza, Catalina, Berrazueta, Ana, Martinez, Esther, Penuelas, Oscar, Jara-Rubio, Ruben, Mallat, Jihad, Thevenin, D., Zogheib, Elie, Mercat, Alain, Levrat, Albrice, Porot, Veronique, Bedock, B., Grech, Ludovic, Plantefeve, Gaetan, Badie, Julio, Besch, Guillaume, Pili-Floury, SÃ©bastien, Guisset, Olivier, Robine, Adrien, Prat, Gwenael, Doise, Jean-Marc, Badet, Michel, Thouret, J. M., Just, Bernard, Perbet, SÃ©bastien, Lautrette, Alexandre, Souweine, B., Chabanne, Russell, Danguy des DÃ©serts, Marc, Rigaud, Jean-Philippe, Marchalot, Antoine, Rigaud, J. P., Bele, Nicolas, Beague, SÃ©bastien, Hours, Sandrine, Marque, Sophie, Durand, Michel, Payen, J. F., Stoclin, Annabelle, Gaffinel, Alain, Winer, Arnaud, Chudeau, Nicolas, Tirot, Patrice, Thyrault, Martial, Paulet, RÃ©mi, Thyrault, M., Aubrun, Frederic, Guerin, Claude, Floccard, Bernard, Rimmele, T., Argaud, Laurent, Hernu, Romain, Crozon Clauzel, Jullien, Wey, Pierre-FranÃ§ois, Bourdin, Gael, Pommier, C., Cueuille, NadÃge, de Varax, null, Marchi, Elisa, Papazian, L., Jochmans, Sebastien, Monchi, M., Jaber, Samir, de Jong, Audrey, Moulaire, Valerie, Capron, Matthieu, Jarrige, L., Barberet, Guillaume, Lakhal, Karim, Rozec, B., Dellamonica, Jean, Robert, Alexandre, Bernardin, G., Danin, Pierre-Eric, Raucoules, M., Runge, Isabelle, Foucrier, Arnaud, Hamada, Sophie, Tesniere, Antoine, Fromentin, MÃ©lanie, Samama, C. M., Mira, Jean-Paul, Diehl, Jean-Luc, Mekontso Dessap, Armand, Arbelot, Charlotte, Demoule, Alexandre, Roche, Anne, Similowski, T., Ricard, Jean-Damien, Gaudry, StÃ©phane, Dreyfuss, D., de Montmolin, Etienne, da Silva, Daniel, Verdiere, B., Ardisson, Fanny, Lemiale, Virginie, Azoulay, Elie, Bruel, CÃ©dric, Tiercelet, Kelly, Fartoukh, Muriel, Voiriot, Guillaume, Hoffmann, Clement, Leclerc, T., Thille, Arnaud, Robert, RÃ©nÃ©, Beuret, Pascal, Beduneau, GaÃ«tan, Beuzelin, Marion, Tamion, F., Morel, JÃ©rÃ ́me, Tremblay, Aymeric, Molliex, S., Amal, Jean-Michel, Meaudre, Eric, Goutorbe, Philippe, Laffon, Marc, Gros, Antoine, Nica, Alexandru, Barjon, Genevieve, Dahyot-Fizelier, Claire, Imzi, Nadia, Gally, Josette, Real, null, Sauneuf, Bertrand, Souloy, Xavier, Girbes, Armand, Tuinman, Pieter Roel, Schultz, Marcus, Winters, Tineke, Mijzen, Lisa, Roekaerts, P. M. H. J., Vermeijden, Wytze, Beishuizen, Albertus, Trof, R., Corsten, Stijn, Kesecioglu, Jozef, Meertens, John, Dieperink, Wim, Pickers, Peter, Roovers, Noortje, Maia, Paulo, Duque, Melanie, Rua, Fernando, Pereira de Figueired, AntÃ3nio Manuel, Ramos, Armindo, Fragoso, Elsa, Azevedo, Pilar, Gouveia, Joao, Costa E. Silva, ZÃ©lia, Silva, Goncalo, Chaves, Susana, Nobrega, J. J., Lopes, LuÃs, Valerio, Bernardino, Araujo, Ana Carolina, de Freitas, Paulo Telles, Bouw, Maria Jose, Melao, Maria, Granja, C., Marcal, Paulo, Fernandes, Antero, Joao, GonÃ§alves Pereira, Maia, DionÃsio Faria, Spadaro, Savino, Volta, Carlo Alberto, Bellani, Giacomo, Citerio, G., Mauri, Tommaso, Alban, Laura, Pesenti, A., Mistraletti, Giovanni, Formenti, Paolo, Tommasino, C., Tardini, Francesca, Fumagalli, R., Colombo, Riccardo, Fossali, Tommaso, Catena, E., Todeschini, Manuel, Gnesin, Paolo, Cracchiolo, Andrea Neville, Palma, Daniela, Tetamo, R., Albiero, Daniela, Costantini, Elena, Raimondi, F., Coppadoro, Andrea, Vascotto, Ettore, Lusenti, F., Becher, Tobias, SchÃ¤dler, Dirk, Weiler, N., Karagiannidis, Christian, Petersson, Johan, Konrad, D., Kawati, Rafael, Wessbergh, Joanna, Valtysson, J., Rockstroh, Matthias, Borgstrom, Sten, Larsson, Niklas, Thunberg, J., Camsooksai, Julie, Briggs, null, Kovari, Ferenc, Cuesta, J., Anwar, Sibs, Oâ€TMBrien, B., Barberis, Luigi, Sturman, J., Mainas, Efstratios, Karatzas, S., Piza, Petr, Sottiaux, Thierry, Adam, J. F., Gawda, Ryszard, Gawor, Maen, Alqdah, M., Cohen, D., Brochard, Laurent, Baker, A., Ã‘amendys-Silva, Silvio Antonio, Garcia-Guillen, Francisco Javier, Morocho Tutillo, Diego Rolando, Jibaja Vega, Manuel, Zakalik, Graciela, Pagella, Gonzalo, Marengo, J., Guã©rin, C, Beuret, P, Constantin, J, Bellani, G, Garcia-Olivares, P, Roca, O, Meertens, J, Maia, P, Becher, T, Peterson, J, Larsson, A, Gurjar, M, Hajjej, Z, Kovari, F, Assiri, A, Mainas, E, Hasan, M, Morocho-Tutillo, D, Baboi, L, Chrã©tien, J, Franã§ois, G, Ayzac, L, Chen, L, Brochard, L, Mercat, A, Sellami, W, Ferjani, M, Al Bshabshe, A, Almekhlafi, G, Mandourah, Y, Rai, V, Marzida, M, Corcoles Gonzalez, V, Sanchez Iniesta, R, Garcia, P, Garcia-Montesinos de la PeÃ±a, M, Garcia Herrera, A, Garcia-de-Acilu, M, Masclans Enviz, J, Mancebo, J, Heili, S, Artigas Raventos, A, Blanch Torra, L, Roche-Campo, F, Rialp, G, Forteza, C, Berrazueta, A, Martinez, E, Penuelas, O, Jara-Rubio, R, Mallat, J, Thevenin, D, Zogheib, E, Levrat, A, Porot, V, Bedock, B, Grech, L, Plantefeve, G, Badie, J, Besch, G, Pili-Floury, S, Guisset, O, Robine, A, Prat, G, Doise, J, Badet, M, Thouret, J, Just, B, Perbet, S, Lautrette, A, Souweine, B, Chabanne, R, Danguy des DÃ©serts, M, Rigaud, J, Marchalot, A, Bele, N, Beague, S, Hours, S, Marque, S, Durand, M, Payen, J, Stoclin, A, Gaffinel, A, Winer, A, Chudeau, N, Tirot, P, Thyrault, M, Paulet, R, Aubrun, F, Guerin, C, Floccard, B, Rimmele, T, Argaud, L, Hernu, R, Crozon Clauzel, J, Wey, P, Bourdin, G, Pommier, C, Cueuille, N, de Varax, N, Marchi, E, Papazian, L, Jochmans, S, Monchi, M, Jaber, S, de Jong, A, Moulaire, V, Capron, M, Jarrige, L, Barberet, G, Lakhal, K, Rozec, B, Dellamonica, J, Robert, A, Bernardin, G, Danin, P, Raucoules, M, Runge, I, Foucrier, A, Hamada, S, Tesniere, A, Fromentin, M, Samama, C, Mira, J, Diehl, J, Mekontso Dessap, A, Arbelot, C, Demoule, A, Roche, A, Similowski, T, Ricard, J, Gaudry, S, Dreyfuss, D, de Montmolin, E, da Silva, D, Verdiere, B, Ardisson, F, Lemiale, V, Azoulay, E, Bruel, C, Tiercelet, K, Fartoukh, M, Voiriot, G, Hoffmann, C, Leclerc, T, Thille, A, Robert, R, Beduneau, G, Beuzelin, M, Tamion, F, Morel, J, Tremblay, A, Molliex, S, Amal, J, Meaudre, E, Goutorbe, P, Laffon, M, Gros, A, Nica, A, Barjon, G, Dahyot-Fizelier, C, Imzi, N, Gally, J, Real, N, Sauneuf, B, Souloy, X, Girbes, A, Tuinman, P, Schultz, M, Winters, T, Mijzen, L, Roekaerts, P, Vermeijden, W, Beishuizen, A, Trof, R, Corsten, S, Kesecioglu, J, Dieperink, W, Pickers, P, Roovers, N, Duque, M, Rua, F, Pereira de Figueired, A, Ramos, A, Fragoso, E, Azevedo, P, Gouveia, J, Costa E. Silva, Z, Silva, G, Chaves, S, Nobrega, J, Lopes, L, Valerio, B, Araujo, A, de Freitas, P, Bouw, M, Melao, M, Granja, C, Marcal, P, Fernandes, A, Joao, G, Maia, D, Spadaro, S, Volta, C, Citerio, G, Mauri, T, Alban, L, Pesenti, A, Mistraletti, G, Formenti, P, Tommasino, C, Tardini, F, Fumagalli, R, Colombo, R, Fossali, T, Catena, E, Todeschini, M, Gnesin, P, Cracchiolo, A, Palma, D, Tetamo, R, Albiero, D, Costantini, E, Raimondi, F, Coppadoro, A, Vascotto, E, Lusenti, F, Schã¤dler, D, Weiler, N, Karagiannidis, C, Petersson, J, Konrad, D, Kawati, R, Wessbergh, J, Valtysson, J, Rockstroh, M, Borgstrom, S, Larsson, N, Thunberg, J, Camsooksai, J, Briggs, N, Cuesta, J, Anwar, S, Oâ€TMBrien, B, Barberis, L, Sturman, J, Karatzas, S, Piza, P, Sottiaux, T, Adam, J, Gawda, R, Gawor, M, Alqdah, M, Cohen, D, Baker, A, Ã‘amendys-Silva, S, Garcia-Guillen, F, Morocho Tutillo, D, Jibaja Vega, M, Zakalik, G, Pagella, G, Marengo, J, GuÃ©rin, C., Beuret, P., Constantin, J. M., Bellani, G., Garcia-Olivares, P., Roca, O., Meertens, J. H., Maia, P. Azevedo, Becher, T., Peterson, J., Larsson, A., Gurjar, M., Hajjej, Z., Kovari, F., Assiri, A. H., Mainas, E., Hasan, M. S., Morocho-Tutillo, D. R., Baboi, L., ChrÃ©tien, J. M., FranÃ§ois, G., Ayzac, L., Chen, L., Brochard, L., Mercat, A., Hajjej, Zied, Sellami, Walid, Ferjani, M., Gurjar, Mohan, Assiri, Amer, Al Bshabshe, Ali, Almekhlafi, Ghaleb, Mandourah, Yasser, Hasan, Mohd Shahnaz, Rai, Vineya, Marzida, M., Corcoles Gonzalez, Virgilio, Sanchez Iniesta, Rafael, Garcia, Pablo, Garcia-Montesinos de la PeÃ±a, Manuel, Garcia Herrera, Adriana, Roca, Oriol, Garcia-de-Acilu, Marina, Masclans Enviz, Joan Ramon, Mancebo, Jordi, Heili, Sarah, Artigas Raventos, Antonio, Blanch Torra, LluÃs, Roche-Campo, Ferran, Rialp, Gemma, Forteza, Catalina, Berrazueta, Ana, Martinez, Esther, Penuelas, Oscar, Jara-Rubio, Ruben, Mallat, Jihad, Thevenin, D., Zogheib, Elie, Mercat, Alain, Levrat, Albrice, Porot, Veronique, Bedock, B., Grech, Ludovic, Plantefeve, Gaetan, Badie, Julio, Besch, Guillaume, Pili-Floury, SÃ©bastien, Guisset, Olivier, Robine, Adrien, Prat, Gwenael, Doise, Jean-Marc, Badet, Michel, Thouret, J. M., Just, Bernard, Perbet, SÃ©bastien, Lautrette, Alexandre, Souweine, B., Chabanne, Russell, Danguy des DÃ©serts, Marc, Rigaud, Jean-Philippe, Marchalot, Antoine, Rigaud, J. P., Bele, Nicolas, Beague, SÃ©bastien, Hours, Sandrine, Marque, Sophie, Durand, Michel, Payen, J. F., Stoclin, Annabelle, Gaffinel, Alain, Winer, Arnaud, Chudeau, Nicolas, Tirot, Patrice, Thyrault, Martial, Paulet, RÃ©mi, Thyrault, M., Aubrun, Frederic, Guerin, Claude, Floccard, Bernard, Rimmele, T., Argaud, Laurent, Hernu, Romain, Crozon Clauzel, Jullien, Wey, Pierre-FranÃ§ois, Bourdin, Gael, Pommier, C., Cueuille, NadÃge, de Varax, null, Marchi, Elisa, Papazian, L., Jochmans, Sebastien, Monchi, M., Jaber, Samir, de Jong, Audrey, Moulaire, Valerie, Capron, Matthieu, Jarrige, L., Barberet, Guillaume, Lakhal, Karim, Rozec, B., Dellamonica, Jean, Robert, Alexandre, Bernardin, G., Danin, Pierre-Eric, Raucoules, M., Runge, Isabelle, Foucrier, Arnaud, Hamada, Sophie, Tesniere, Antoine, Fromentin, MÃ©lanie, Samama, C. M., Mira, Jean-Paul, Diehl, Jean-Luc, Mekontso Dessap, Armand, Arbelot, Charlotte, Demoule, Alexandre, Roche, Anne, Similowski, T., Ricard, Jean-Damien, Gaudry, StÃ©phane, Dreyfuss, D., de Montmolin, Etienne, da Silva, Daniel, Verdiere, B., Ardisson, Fanny, Lemiale, Virginie, Azoulay, Elie, Bruel, CÃ©dric, Tiercelet, Kelly, Fartoukh, Muriel, Voiriot, Guillaume, Hoffmann, Clement, Leclerc, T., Thille, Arnaud, Robert, RÃ©nÃ©, Beuret, Pascal, Beduneau, GaÃ«tan, Beuzelin, Marion, Tamion, F., Morel, JÃ©rÃ ́me, Tremblay, Aymeric, Molliex, S., Amal, Jean-Michel, Meaudre, Eric, Goutorbe, Philippe, Laffon, Marc, Gros, Antoine, Nica, Alexandru, Barjon, Genevieve, Dahyot-Fizelier, Claire, Imzi, Nadia, Gally, Josette, Real, null, Sauneuf, Bertrand, Souloy, Xavier, Girbes, Armand, Tuinman, Pieter Roel, Schultz, Marcus, Winters, Tineke, Mijzen, Lisa, Roekaerts, P. M. H. J., Vermeijden, Wytze, Beishuizen, Albertus, Trof, R., Corsten, Stijn, Kesecioglu, Jozef, Meertens, John, Dieperink, Wim, Pickers, Peter, Roovers, Noortje, Maia, Paulo, Duque, Melanie, Rua, Fernando, Pereira de Figueired, AntÃ3nio Manuel, Ramos, Armindo, Fragoso, Elsa, Azevedo, Pilar, Gouveia, Joao, Costa E. Silva, ZÃ©lia, Silva, Goncalo, Chaves, Susana, Nobrega, J. J., Lopes, LuÃs, Valerio, Bernardino, Araujo, Ana Carolina, de Freitas, Paulo Telles, Bouw, Maria Jose, Melao, Maria, Granja, C., Marcal, Paulo, Fernandes, Antero, Joao, GonÃ§alves Pereira, Maia, DionÃsio Faria, Spadaro, Savino, Volta, Carlo Alberto, Bellani, Giacomo, Citerio, G., Mauri, Tommaso, Alban, Laura, Pesenti, A., Mistraletti, Giovanni, Formenti, Paolo, Tommasino, C., Tardini, Francesca, Fumagalli, R., Colombo, Riccardo, Fossali, Tommaso, Catena, E., Todeschini, Manuel, Gnesin, Paolo, Cracchiolo, Andrea Neville, Palma, Daniela, Tetamo, R., Albiero, Daniela, Costantini, Elena, Raimondi, F., Coppadoro, Andrea, Vascotto, Ettore, Lusenti, F., Becher, Tobias, SchÃ¤dler, Dirk, Weiler, N., Karagiannidis, Christian, Petersson, Johan, Konrad, D., Kawati, Rafael, Wessbergh, Joanna, Valtysson, J., Rockstroh, Matthias, Borgstrom, Sten, Larsson, Niklas, Thunberg, J., Camsooksai, Julie, Briggs, null, Kovari, Ferenc, Cuesta, J., Anwar, Sibs, Oâ€TMBrien, B., Barberis, Luigi, Sturman, J., Mainas, Efstratios, Karatzas, S., Piza, Petr, Sottiaux, Thierry, Adam, J. F., Gawda, Ryszard, Gawor, Maen, Alqdah, M., Cohen, D., Brochard, Laurent, Baker, A., Ã‘amendys-Silva, Silvio Antonio, Garcia-Guillen, Francisco Javier, Morocho Tutillo, Diego Rolando, Jibaja Vega, Manuel, Zakalik, Graciela, Pagella, Gonzalo, and Marengo, J.
Abstract: Introduction: While prone positioning (PP) has been shown to improve patient survival in moderate to severe acute respiratory distress syndrome (ARDS) patients, the rate of application of PP in clinical practice still appears low. Aim: This study aimed to determine the prevalence of use of PP in ARDS patients (primary endpoint), the physiological effects of PP, and the reasons for not using it (secondary endpoints). Methods: The APRONET study was a prospective international 1-day prevalence study performed four times in April, July, and October 2016 and January 2017. On each study day, investigators in each ICU had to screen every patient. For patients with ARDS, use of PP, gas exchange, ventilator settings and plateau pressure (Pplat) were recorded before and at the end of the PP session. Complications of PP and reasons for not using PP were also documented. Values are presented as median (1st–3rd quartiles). Results: Over the study period, 6723 patients were screened in 141 ICUs from 20 countries (77% of the ICUs were European), of whom 735 had ARDS and were analyzed. Overall 101 ARDS patients had at least one session of PP (13.7%), with no differences among the 4 study days. The rate of PP use was 5.9% (11/187), 10.3% (41/399) and 32.9% (49/149) in mild, moderate and severe ARDS, respectively (P = 0.0001). The duration of the first PP session was 18 (16–23) hours. Measured with the patient in the supine position before and at the end of the first PP session, PaO 2 /F I O 2 increased from 101 (76–136) to 171 (118–220) mmHg (P = 0.0001) driving pressure decreased from 14 [11–17] to 13 [10–16] cmH 2 O (P = 0.001), and Pplat decreased from 26 [23–29] to 25 [23–28] cmH 2 O (P = 0.04). The most prevalent reason for not using PP (64.3%) was that hypoxemia was not considered sufficiently severe. Complications were reported in 12 patients (11.9%) in whom PP was used (pressure sores in five, hypoxemia in two, endotracheal tube-related in two ocular in two, and a transient
Published: 2018

6. Bedside selection of positive end-expiratory pressure by electrical impedance tomography in hypoxemic patients: a feasibility study

Author: Eronia, N, Mauri, T, Maffezzini, E, Gatti, S, Bronco, A, Alban, L, Binda, F, Sasso, T, Marenghi, C, Grasselli, G, Foti, G, Pesenti, A, Bellani, G, ERONIA, NILDE, MAURI, TOMMASO, BRONCO, ALFIO, GRASSELLI, GIACOMO, FOTI, GIUSEPPE, PESENTI, ANTONIO MARIA, BELLANI, GIACOMO, Eronia, N, Mauri, T, Maffezzini, E, Gatti, S, Bronco, A, Alban, L, Binda, F, Sasso, T, Marenghi, C, Grasselli, G, Foti, G, Pesenti, A, Bellani, G, ERONIA, NILDE, MAURI, TOMMASO, BRONCO, ALFIO, GRASSELLI, GIACOMO, FOTI, GIUSEPPE, PESENTI, ANTONIO MARIA, and BELLANI, GIACOMO
Abstract: Background: Positive end-expiratory pressure (PEEP) is a key element of mechanical ventilation. It should optimize recruitment, without causing excessive overdistension, but controversy exists on the best method to set it. The purpose of the study was to test the feasibility of setting PEEP with electrical impedance tomography in order to prevent lung de-recruitment following a recruitment maneuver. We enrolled 16 patients undergoing mechanical ventilation with PaO2/FiO2 <300 mmHg. In all patients, under constant tidal volume (6–8 ml/kg) PEEP was set based on the PEEP/FiO2 table proposed by the ARDS network (PEEPARDSnet). We performed a recruitment maneuver and monitored the end-expiratory lung impedance (EELI) over 10 min. If the EELI signal decreased during this period, the recruitment maneuver was repeated and PEEP increased by 2 cmH2O. This procedure was repeated until the EELI maintained a stability over time (PEEPEIT). Results: The procedure was feasible in 87% patients. PEEPEIT was higher than PEEPARDSnet (13 ± 3 vs. 9 ± 2 cmH2O, p < 0.001). PaO2/FiO2 improved during PEEPEIT and driving pressure decreased. Recruited volume correlated with the decrease in driving pressure but not with oxygenation improvement. Finally, regional alveolar hyperdistention and collapse was reduced in dependent lung layers and increased in non-dependent lung layers. Conclusions: In hypoxemic patients, a PEEP selection strategy aimed at stabilizing alveolar recruitment guided by EIT at the bedside was feasible and safe. This strategy led, in comparison with the ARDSnet table, to higher PEEP, improved oxygenation and reduced driving pressure, allowing to estimate the relative weight of overdistension and recruitment.
Published: 2017

7. Intracerebral hemorrhage in ICU: is it worth treating?

Author: Sivakumar, S, Taccone, F, Desai, K, Lazaridis, C, Skarzynski, M, Sekhon, M, Henderson, W, Griesdale, D, Chapple, L, Deane, A, Williams, L, Strickland, R, Lange, K, Heyland, D, Chapman, M, Rowland, M, Garry, P, Westbrook, J, Corkill, R, Antoniades, C, Pattinson, K, Fatania, G, Strong, A, Myers, R, Jermaine, C, Robertson, C, Rusin, C, Hofmeijer, J, Sondag, L, Tjepkema Cloostermans, M, Beishuizen, A, Bosch, F, van Putten, M, Carteron, L, Patet, C, Solari, D, Oddo, M, Ali, M, Dias, C, Almeida, R, Vaz Ferreira, A, Silva, J, Monteiro, E, Cerejo, A, Rocha, A, Elsayed, A, Abougabal, A, Beshey, B, Alzahaby, K, Pozzebon, S, Ortiz, A, Cristallini, S, Lheureux, O, Brasseur, A, Vincent, J, Creteur, J, Hravnak, M, Yousef, K, Chang, Y, Crago, E, Friedlander, R, Abdelmonem, S, Tahon, S, Helmy, T, Meligy, H, Puig, F, Dunn Siegrist, I, Pugin, J, Gupta, S, Govil, D, Srinivasan, S, Patel, S, N, J, Gupta, A, Tomar, D, Shafi, M, Harne, R, Arora, D, Talwar, N, Mazumdar, S, Papakrivou, E, Makris, D, Manoulakas, E, Tsolaki, B, Karadodas, B, Zakynthinos, E, Garcia, I, Martin, A, Encinares, V, Ibañez, M, Montero, J, Labrador, G, Cangueiro, T, Poulose, V, Koh, J, Kam, J, Yeter, H, Kara, A, Aktepe, O, Topeli, A, Tsolakoglou, I, Intas, G, Stergiannis, P, Kolaros, A, Chalari, E, Athanasiadou, E, Martika, A, Fildisis, G, Faivre, V, Mengelle, C, Favier, B, Payen, D, Poppe, A, Winkler, M, Mudersbach, E, Schreiber, J, Wruck, M, Schwedhelm, E, Kluge, S, Zöllner, C, Tavladaki, T, Spanaki, A, Dimitriou, H, Kondili, E, Choulaki, C, Meleti, E, Kafetzopoulos, D, Georgopoulos, D, Briassoulis, G, la Torre, A, de la Torre Prados, M, Tsvetanova Spasova, T, Nuevo Ortega, P, Rueda Molina, C, Fernández Porcel, A, Camara Sola, E, Salido Díaz, L, García Alcántara, A, Meleti, D, Suberviola, B, Riera, J, Rellan, L, Sanchez, M, Robles, J, Lopez, E, Vicente, R, Miñambres, E, Santibañez, M, Le Guen, M, Moore, J, Mason, N, Windpassinger, M, Plattner, O, Mascha, E, Sessler, D, Research, O, Melia, U, Fontanet, J, van den Berg, J, Struys, M, Vereecke, H, Jensen, E, Rood, P, van de Schoor, F, van Tertholen, K, Pickkers, P, van den Boogaard, M, Beardow, Z, Redhead, H, Paramasivam, K, Numan, T, Kamper, A, Peelen, L, Zeman, P, Slooter, A, van Ewijk, C, Jacobs, G, Girbes, A, Myatra, S, Harish, M, Prabu, N, Siddiqui, S, Kulkarni, A, Divatia, J, Murbach, L, Leite, M, Osaku, E, Costa, C, Pelenz, M, Neitzke, N, Moraes, M, Jaskowiak, J, Silva, M, Zaponi, R, Abentroth, L, Ogasawara, S, Jorge, A, Duarte, P, Hernández Sánchez, N, Sánchez Hurtado, L, García Guillen, F, Ñamendys Silva, S, Maghsoudi, B, Emami, M, Khosravi, M, Zand, F, Tabatabaie, H, Masjedi, M, Sabetiyan, G, Mokri, A, Troubleyn, J, Diltoer, M, Jacobs, R, Nguyen, D, De Waele, E, De Regt, J, Honoré, P, Van Gorp, V, Spapen, H, Contreras, R, Toapanta, N, Moreno, G, Sabater, J, Torrado, H, Gonzalez, M, Marin, M, Farigola, E, Gonzalez, A, Fernandez, J, Vera, A, Gisbert, X, Juliá, C, Uya, J, Corral, L, Elias Jones, I, Gemmell, L, Mackay, A, Randall, D, Adwaney, A, Blunden, M, Prowle, J, Kirwan, C, Thomas, N, Owen, H, Darwin, L, Conway, D, Atkinson, D, Sharman, M, Barbanti, C, Amour, J, Gaudard, P, Rozec, B, Mauriat, P, M'Rini, M, Leger, P, Cambonie, G, Liet, J, Girard, C, Laroche, S, Damas, P, Assaf, Z, Loron, G, Lecourt, L, Pouard, P, Kim, S, Na, S, Kim, J, Oh, S, Jung, C, Yoo, S, Min, S, Chung, E, Lee, H, Lee, N, Lee, K, Suh, K, Ryu, H, Marshall, D, Goodson, R, Salciccioli, J, Shalhoub, J, Potter, E, Kirk Bayley, J, Karanjia, N, Forni, L, Creagh Brown, B, Bossy, M, Nyman, M, Tailor, A, D'Antini, D, Spadaro, S, Valentino, F, Sollitto, F, Cinnella, G, Mirabella, L, Calvo, F, Bejarano, N, Padilla, D, Baladron, V, Villajero, P, Villazala, R, Redondo, J, Yuste, A, Liu, J, Shen, F, Teboul, J, Anguel, N, Beurton, A, Bezaz, N, Richard, C, Monnet, X, Fossali, T, Colombo, R, Ottolina, D, Rossetti, M, Mazzucco, C, Marchi, A, Porta, A, Catena, E, Tollisen, K, Andersen, G, Heyerdahl, F, Jacobsen, D, de Waard, M, van 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Domenech, J, Montalvo, A, Chornet, T, Martinez, P, Ribas, M, Costa, R, Ortega, A, Forbes, C, Prescott, H, Lal, A, Khan, F, Dela Pena, E, Dizon, J, Wong, C, Garach, M, Romero, O, Puerta, R, Diaz, F, Bailon, A, Pinel, A, Maldonado, L, Kalaiselvan, M, Kumar, R, Renuka, M, De Rosa, S, Ferrari, F, Checcacci, S, Rigobello, A, Joannidis, M, Politi, F, Pellizzari, A, Bonato, R, Fernandez Carmona, A, Macias Guarasa, I, Gutierrez Rodriguez, R, Martinez Lopez, P, Diaz Castellanos, M, Arias Diaz, M, Aguilar Alonso, E, Nikandish, R, Artemenko, V, Budnyuk, A, Bassi, G, Senussi, T, Idone, F, Xiol, E, Travierso, C, Chiurazzi, C, Motos, A, Amaro, R, Hua, Y, Fernández Barat, L, Ranzani, O, Bobi, Q, Rigol, M, Youn, A, Hwang, J, Ossorio, M, Figueira, H, Oliveira, R, Mota, A, Kamp, O, Cruciger, O, Aach, M, Kaczmarek, C, Waydhas, C, Schildhauer, T, Hamsen, U, Camprubí Rimblas, M, Chimenti, L, Guillamat Prats, R, Lebouvier, T, Bringué, J, Tijero, J, Gómez, M, Blanch, L, Tagliabue, G, Ji, M, Jagers, J, Easton, P, Hong, J, Shin, M, Park, M, Pomprapa, A, Hofferberth, M, Russ, M, Braun, W, Walter, M, Francis, R, Lachmann, B, Leonhardt, S, Landaverde López, A, Canedo Castillo, N, Esquivel Chávez, A, Arvizu Tachiquín, P, Baltazar Torres, J, Cardoso, V, Krystopchuk, A, Castro, S, Melão, L, Firmino, S, Marreiros, A, Almaziad, S, Kubbara, A, Barnett, W, Nakity, R, Alamoudi, W, Altook, R, Tarazi, T, Fida, M, Safi, F, Assaly, R, Santini, A, Milesi, M, Maraffi, T, Pugni, P, Cavenago, M, Gattinoni, L, Protti, A, Perchiazzi, G, Borges, J, Bayat, S, Porra, L, Broche, L, Hedenstierna, G, Larsson, A, Roneus, A, Segelsjö, M, Vestito, M, Gremo, E, Nyberg, A, Castegren, M, Pikwer, A, Yoshida, T, Engelberts, D, Otulakowski, G, Katira, B, Post, M, Amato, M, Koch, N, Hoellthaler, J, Mair, S, Phillip, V, Beitz, A, Baladrón, V, Villarejo, P, Steenstra, R, Banierink, H, Hof, J, Hoekstra, M, Sterz, F, Horvatits, K, Herkner, H, Kott, M, Zitta, K, Brandt, B, Schildhauer, C, Elke, G, Hummitzsch, L, Albrecht, M, González, L, Alonso, D, Sánchez, R, Lucas, J, Ferlitsch, A, Fauler, G, Trauner, M, Pischke, S, Fischer, L, Thaiss, F, Koch, M, Bangert, K, Lohse, A, Nashan, B, Sterneck, M, Faenza, S, Siniscalchi, A, Pierucci, E, Mancini, E, Ricci, D, Gemelli, C, Cuoghi, A, Magnani, S, Atti, M, Sotos, F, Cánovas, J, López, A, Burruezo, A, Torres, D, Herrera Gutierrez, M, Barrueco Francioni, J, Arias Verdú, D, Lozano Saez, R, Quesada Garcia, G, Seller Pérez, G, Figueiredo, A, Anzola, Y, Pereira, R, Bento, L, Lai, M, Deiana, M, Seller Perez, G, Vardas, K, Ilia, S, Sertedaki, A, Charmadari, E, Stratakis, C, Briassouli, E, Goukos, D, Psarra, K, Botoula, E, Tsagarakis, S, Mageira, E, Routsi, C, Nanas, S, Campello, E, Radu, C, Su, H, Lam, Y, Willis, K, Pullar, V, Hubner, R, Tsang, J, de Guadiana Romualdo, L, Rebollo Acebes, S, Esteban Torrella, P, Jiménez Sánchez, R, Jiménez Santos, E, Ortín Freire, A, Hernando Holgado, A, Albaladejo Otón, M, Coelho, L, Rabello, L, Póvoa, P, Varis, E, Poukkanen, M, Jacob, S, Takala, J, Wilkman, E, Lundberg, O, Bergenzaun, L, Rydén, J, Rosenqvist, M, Melander, O, Chew, M, Kishihara, Y, Yasuda, H, Jimenez, R, Torrella, P, Fernandez, A, Sanchez, S, Ortin, A, Prats, R, Aguilera, E, Marti, D, Fernandez, L, Ferrer, M, Lanziotti, V, Pulcheri, L, Ribeiro, M, Barbosa, A, E. Silva, J, Soares, M, Marqués, M, Moreno, A, Pizarraya, A, Smani, Y, Connell, M, Zhang, L, Parker, R, Banerjee, I, Clermont, G, Norberg, E, Oras, J, Cuisinier, A, Maufrais, C, Payen, J, Nottin, S, Walther, G, Arib, S, Bilotta, F, Badenes, R, Rubulotta, F, Mirek, S, Monfort, B, Stazi, E, Roig, A, Magnoni, S, Marando, M, Pifferi, S, Conte, V, Ortolano, F, Carbonara, M, Bertani, G, Scola, E, Cadioli, M, Triulzi, F, Colombo, A, Stocchetti, N, Rotzel, H, Lázaro, A, Prada, D, Guimillo, M, Piqueras, C, Guia, J, Simon, M, Arizmendi, A, Carratalá, A, El Maraghi, S, Yehia, A, Bakry, M, Shoman, A, Backes, F, Bianchin, M, Vieira, S, de Souza, A, Backes, A, Klein, C, Arunkumar, A, Lozano, A, Gallaher, C, Cattlin, S, Gordon, S, Picard, J, Fontana, V, Bond, O, Nobile, L, Mrozek, S, Delamarre, L, Capilla, F, Al Saati, T, Fourcade, O, Dominguez Berrot, A, Gonzalez Vaquero, M, Vallejo Pascual, M, Gupta, D, Ivory, B, Chopra, M, Mccarthy, J, Felderhof, C, Macneil, C, Maggiorini, M, Duska, F, Fumis, R, Junior, J, Amarante, G, Skorko, A, Sanders, S, Aron, J, Kroll, R, Redfearn, C, Krishnan, P, Khalil, J, Kongpolprom, N, Gulia, V, Lourenço, E, Duro, C, Baptista, G, Alves, A, Arminda, B, Rodrigues, M, Hayward, J, Baldwin, F, Gray, R, Katinakis, P, Stijf, M, Ten Kleij, M, Jansen Frederiks, M, Broek, R, de Bruijne, M, Spronk, P, Sinha, K, Luney, M, Palmer, K, Keating, L, Abu Habsa, M, Bahl, R, Baskaralingam, N, Ahmad, A, Kanapeckaite, L, Bhatti, P, Glace, S, Jeyabraba, S, Lewis, H, Kostopoulos, A, Raja, M, West, A, Ely, A, Turkoglu, L, Zolfaghari, P, Baptista, J, Marques, M, Martins, P, Pimentel, J, Su, Y, Villacres, S, Stone, M, Parsikia, A, Medar, S, O'Dea, K, Porter, J, Tirlapur, N, Jonathan, J, Singh, S, Takata, M, Mcwhirter, E, Lyon, R, Hariz, M, Azmi, E, Alkhan, J, Movsisyan, V, Petrikov, S, Marutyan, Z, Aliev, I, Evdokimov, A, Antonucci, E, Merz, T, Hartmann, C, Calzia, E, Radermacher, P, Nußbaum, B, Huber Lang, M, Gröger, M, Svoren Jabalera, E, Davenport, E, Humburg, P, Knight, J, Hinds, C, Jun, I, Kim, W, Besch, G, Perrotti, A, Puyraveau, M, Baltres, M, Samain, E, Chocron, S, Pili Floury, S, Plata Menchaca, E, Sabater Riera, J, Estruch, M, Boza, E, Toscana Fernández, J, Bruguera Pellicer, E, Ordoñez Llanos, J, Pérez Fernández, X, Cavaleiro, P, Tralhão, A, Arrigo, M, Lopes, J, Lebrun, M, Cholley, B, Perezvela, J, Marinmateos, H, Rivera, J, Llorente, M, De Marcos, B, Fernandez, F, Laborda, C, Zamora, D, Delgado, J, Imperiali, C, Dastis, M, Górka, J, Górka, K, Iwaniec, T, Frołow, M, Polok, K, Fronczek, J, Kózka, M, Musiał, J, Szczeklik, W, Sileli, M, Moursia, C, Maleoglou, H, Leleki, K, Uz, Z, Ince, Y, Papatella, R, Bulent, E, De Mol, B, Vicka, V, Gineityte, D, Ringaitiene, D, Norkiene, I, Sipylaite, J, Möller, C, Thomas Rueddel, D, Vlasakov, V, Rochwerg, B, Theurer, P, Al Sibai, J, Camblor, P, Fernandez, P, Gala, J, Guisasola, J, Tamura, T, Miyajima, I, Yamashita, K, Yokoyama, M, Dalampini, E, Nastou, M, Baddour, A, Ignatiadis, A, Asteri, T, Hathorn, K, Purtle, S, Viana, M, Tonietto, T, Gross, L, Costa, V, Tavares, A, Lisboa, B, Moraes, R, Viana, L, Azevedo, M, Ceniccola, G, Pequeno, R, Holanda, T, Mendonça, V, Araújo, W, Carvalho, L, Segaran, E, Vickers, L, Brinchmann, K, Wignall, I, De Brito Ashurst, I, Del Olmo, R, Vaquerizo, C, Carreño, R, Gálvez, V, Kaminsky, G, Nieto, B, Fuentes, M, De la Torre, M, Torres, E, Alonso, A, Velayos, C, Saldaña, T, Escribá, A, Grip, J, Kölegård, R, Sundblad, P, Rooyackers, O, Naser, B, Jaziri, F, Jazia, A, Barghouth, M, Hentati, O, Skouri, W, El Euch, M, Mahfoudhi, M, Turki, S, Abdelghni, K, Abdallah, B, Maha, B, Lorente, M, Włudarczyk, A, Hałek, A, Bargouth, M, Bennasr, M, Abdelghani, K, Abdallah, T, Geenen, I, Parienti, J, Shum, H, King, H, Yan, W, Londoño, J, Cardenas, C, Pedrosa, M, Gubianas, C, Bertolin, C, Batllori, N, Sirvent, J, Mukhopadhyay, A, Chan, H, Kowitlawakul, Y, Remani, D, Leong, C, Henry, C, Puthucheary, Z, Mendsaikhan, N, Begzjav, T, Lundeg, G, Dünser, M, Welsh, S, Guerra, E, Zerpa, M, Zechner, F, Berdaguer, F, Risso Vazquez, A, Masevicius, F, Greaney, D, Magee, A, Fitzpatrick, G, Lugo Cob, R, Tejeda Huezo, B, Cano Oviedo, A, Aydogan, M, Togal, T, Taha, A, Chai, H, Kam, C, Razali, S, Sivasamy, V, Kuan, L, Morales, M, Pires, T, Azevedo, L, Azevedo, L., GIUSSANI, CARLO GIORGIO, SGANZERLA, ERIK PIETRO, and CITERIO, GIUSEPPE
Published: 2016

8. Intracerebral hemorrhage in ICU: is it worth treating?

Author: Sivakumar, S, Taccone, F, Desai, K, Lazaridis, C, Skarzynski, M, Sekhon, M, Henderson, W, Griesdale, D, Chapple, L, Deane, A, Williams, L, Strickland, R, Lange, K, Heyland, D, Chapman, M, Rowland, M, Garry, P, Westbrook, J, Corkill, R, Antoniades, C, Pattinson, K, Fatania, G, Strong, A, Myers, R, Jermaine, C, Robertson, C, Rusin, C, Hofmeijer, J, Sondag, L, Tjepkema Cloostermans, M, Beishuizen, A, Bosch, F, van Putten, M, Carteron, L, Patet, C, Solari, D, Oddo, M, Ali, M, Dias, C, Almeida, R, Vaz Ferreira, A, Silva, J, Monteiro, E, Cerejo, A, Rocha, A, Elsayed, A, Abougabal, A, Beshey, B, Alzahaby, K, Pozzebon, S, Ortiz, A, Cristallini, S, Lheureux, O, Brasseur, A, Vincent, J, Creteur, J, Hravnak, M, Yousef, K, Chang, Y, Crago, E, Friedlander, R, Abdelmonem, S, Tahon, S, Helmy, T, Meligy, H, Puig, F, Dunn Siegrist, I, Pugin, J, Gupta, S, Govil, D, Srinivasan, S, Patel, S, N, J, Gupta, A, Tomar, D, Shafi, M, Harne, R, Arora, D, Talwar, N, Mazumdar, S, Papakrivou, E, Makris, D, Manoulakas, E, Tsolaki, B, Karadodas, B, Zakynthinos, E, Garcia, I, Martin, A, Encinares, V, Ibañez, M, Montero, J, Labrador, G, Cangueiro, T, Poulose, V, Koh, J, Kam, J, Yeter, H, Kara, A, Aktepe, O, Topeli, A, Tsolakoglou, I, Intas, G, Stergiannis, P, Kolaros, A, Chalari, E, Athanasiadou, E, Martika, A, Fildisis, G, Faivre, V, Mengelle, C, Favier, B, Payen, D, Poppe, A, Winkler, M, Mudersbach, E, Schreiber, J, Wruck, M, Schwedhelm, E, Kluge, S, Zöllner, C, Tavladaki, T, Spanaki, A, Dimitriou, H, Kondili, E, Choulaki, C, Meleti, E, Kafetzopoulos, D, Georgopoulos, D, Briassoulis, G, la Torre, A, de la Torre Prados, M, Tsvetanova Spasova, T, Nuevo Ortega, P, Rueda Molina, C, Fernández Porcel, A, Camara Sola, E, Salido Díaz, L, García Alcántara, A, Meleti, D, Suberviola, B, Riera, J, Rellan, L, Sanchez, M, Robles, J, Lopez, E, Vicente, R, Miñambres, E, Santibañez, M, Le Guen, M, Moore, J, Mason, N, Windpassinger, M, Plattner, O, Mascha, E, Sessler, D, Research, O, Melia, U, Fontanet, J, van den Berg, J, Struys, M, Vereecke, H, Jensen, E, Rood, P, van de Schoor, F, van Tertholen, K, Pickkers, P, van den Boogaard, M, Beardow, Z, Redhead, H, Paramasivam, K, Numan, T, Kamper, A, Peelen, L, Zeman, P, Slooter, A, van Ewijk, C, Jacobs, G, Girbes, A, Myatra, S, Harish, M, Prabu, N, Siddiqui, S, Kulkarni, A, Divatia, J, Murbach, L, Leite, M, Osaku, E, Costa, C, Pelenz, M, Neitzke, N, Moraes, M, Jaskowiak, J, Silva, M, Zaponi, R, Abentroth, L, Ogasawara, S, Jorge, A, Duarte, P, Hernández Sánchez, N, Sánchez Hurtado, L, García Guillen, F, Ñamendys Silva, S, Maghsoudi, B, Emami, M, Khosravi, M, Zand, F, Tabatabaie, H, Masjedi, M, Sabetiyan, G, Mokri, A, Troubleyn, J, Diltoer, M, Jacobs, R, Nguyen, D, De Waele, E, De Regt, J, Honoré, P, Van Gorp, V, Spapen, H, Contreras, R, Toapanta, N, Moreno, G, Sabater, J, Torrado, H, Gonzalez, M, Marin, M, Farigola, E, Gonzalez, A, Fernandez, J, Vera, A, Gisbert, X, Juliá, C, Uya, J, Corral, L, Elias Jones, I, Gemmell, L, 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Albrecht, M, González, L, Alonso, D, Sánchez, R, Lucas, J, Ferlitsch, A, Fauler, G, Trauner, M, Pischke, S, Fischer, L, Thaiss, F, Koch, M, Bangert, K, Lohse, A, Nashan, B, Sterneck, M, Faenza, S, Siniscalchi, A, Pierucci, E, Mancini, E, Ricci, D, Gemelli, C, Cuoghi, A, Magnani, S, Atti, M, Sotos, F, Cánovas, J, López, A, Burruezo, A, Torres, D, Herrera Gutierrez, M, Barrueco Francioni, J, Arias Verdú, D, Lozano Saez, R, Quesada Garcia, G, Seller Pérez, G, Figueiredo, A, Anzola, Y, Pereira, R, Bento, L, Lai, M, Deiana, M, Seller Perez, G, Vardas, K, Ilia, S, Sertedaki, A, Charmadari, E, Stratakis, C, Briassouli, E, Goukos, D, Psarra, K, Botoula, E, Tsagarakis, S, Mageira, E, Routsi, C, Nanas, S, Campello, E, Radu, C, Su, H, Lam, Y, Willis, K, Pullar, V, Hubner, R, Tsang, J, de Guadiana Romualdo, L, Rebollo Acebes, S, Esteban Torrella, P, Jiménez Sánchez, R, Jiménez Santos, E, Ortín Freire, A, Hernando Holgado, A, Albaladejo Otón, M, Coelho, L, Rabello, L, Póvoa, P, Varis, E, Poukkanen, M, Jacob, S, Takala, J, Wilkman, E, Lundberg, O, Bergenzaun, L, Rydén, J, Rosenqvist, M, Melander, O, Chew, M, Kishihara, Y, Yasuda, H, Jimenez, R, Torrella, P, Fernandez, A, Sanchez, S, Ortin, A, Prats, R, Aguilera, E, Marti, D, Fernandez, L, Ferrer, M, Lanziotti, V, Pulcheri, L, Ribeiro, M, Barbosa, A, E. Silva, J, Soares, M, Marqués, M, Moreno, A, Pizarraya, A, Smani, Y, Connell, M, Zhang, L, Parker, R, Banerjee, I, Clermont, G, Norberg, E, Oras, J, Cuisinier, A, Maufrais, C, Payen, J, Nottin, S, Walther, G, Arib, S, Bilotta, F, Badenes, R, Rubulotta, F, Mirek, S, Monfort, B, Stazi, E, Roig, A, Magnoni, S, Marando, M, Pifferi, S, Conte, V, Ortolano, F, Carbonara, M, Bertani, G, Scola, E, Cadioli, M, Triulzi, F, Colombo, A, Stocchetti, N, Rotzel, H, Lázaro, A, Prada, D, Guimillo, M, Piqueras, C, Guia, J, Simon, M, Arizmendi, A, Carratalá, A, El Maraghi, S, Yehia, A, Bakry, M, Shoman, A, Backes, F, Bianchin, M, Vieira, S, de Souza, A, Backes, A, Klein, C, Arunkumar, A, Lozano, A, Gallaher, C, Cattlin, S, Gordon, S, Picard, J, Fontana, V, Bond, O, Nobile, L, Mrozek, S, Delamarre, L, Capilla, F, Al Saati, T, Fourcade, O, Dominguez Berrot, A, Gonzalez Vaquero, M, Vallejo Pascual, M, Gupta, D, Ivory, B, Chopra, M, Mccarthy, J, Felderhof, C, Macneil, C, Maggiorini, M, Duska, F, Fumis, R, Junior, J, Amarante, G, Skorko, A, Sanders, S, Aron, J, Kroll, R, Redfearn, C, Krishnan, P, Khalil, J, Kongpolprom, N, Gulia, V, Lourenço, E, Duro, C, Baptista, G, Alves, A, Arminda, B, Rodrigues, M, Hayward, J, Baldwin, F, Gray, R, Katinakis, P, Stijf, M, Ten Kleij, M, Jansen Frederiks, M, Broek, R, de Bruijne, M, Spronk, P, Sinha, K, Luney, M, Palmer, K, Keating, L, Abu Habsa, M, Bahl, R, Baskaralingam, N, Ahmad, A, Kanapeckaite, L, Bhatti, P, Glace, S, Jeyabraba, S, Lewis, H, Kostopoulos, A, Raja, M, West, A, Ely, A, Turkoglu, L, Zolfaghari, P, Baptista, J, Marques, M, Martins, P, Pimentel, J, Su, Y, Villacres, S, Stone, M, Parsikia, A, Medar, S, O'Dea, K, Porter, J, Tirlapur, N, Jonathan, J, Singh, S, Takata, M, Mcwhirter, E, Lyon, R, Hariz, M, Azmi, E, Alkhan, J, Movsisyan, V, Petrikov, S, Marutyan, Z, Aliev, I, Evdokimov, A, Antonucci, E, Merz, T, Hartmann, C, Calzia, E, Radermacher, P, Nußbaum, B, Huber Lang, M, Gröger, M, Svoren Jabalera, E, Davenport, E, Humburg, P, Knight, J, Hinds, C, Jun, I, Kim, W, Besch, G, Perrotti, A, Puyraveau, M, Baltres, M, Samain, E, Chocron, S, Pili Floury, S, Plata Menchaca, E, Sabater Riera, J, Estruch, M, Boza, E, Toscana Fernández, J, Bruguera Pellicer, E, Ordoñez Llanos, J, Pérez Fernández, X, Cavaleiro, P, Tralhão, A, Arrigo, M, Lopes, J, Lebrun, M, Cholley, B, Perezvela, J, Marinmateos, H, Rivera, J, Llorente, M, De Marcos, B, Fernandez, F, Laborda, C, Zamora, D, Delgado, J, Imperiali, C, Dastis, M, Górka, J, Górka, K, Iwaniec, T, Frołow, M, Polok, K, Fronczek, J, Kózka, M, Musiał, J, Szczeklik, W, Sileli, M, Moursia, C, Maleoglou, H, Leleki, K, Uz, Z, Ince, Y, Papatella, R, Bulent, E, De Mol, B, Vicka, V, Gineityte, D, Ringaitiene, D, Norkiene, I, Sipylaite, J, Möller, C, Thomas Rueddel, D, Vlasakov, V, Rochwerg, B, Theurer, P, Al Sibai, J, Camblor, P, Fernandez, P, Gala, J, Guisasola, J, Tamura, T, Miyajima, I, Yamashita, K, Yokoyama, M, Dalampini, E, Nastou, M, Baddour, A, Ignatiadis, A, Asteri, T, Hathorn, K, Purtle, S, Viana, M, Tonietto, T, Gross, L, Costa, V, Tavares, A, Lisboa, B, Moraes, R, Viana, L, Azevedo, M, Ceniccola, G, Pequeno, R, Holanda, T, Mendonça, V, Araújo, W, Carvalho, L, Segaran, E, Vickers, L, Brinchmann, K, Wignall, I, De Brito Ashurst, I, Del Olmo, R, Vaquerizo, C, Carreño, R, Gálvez, V, Kaminsky, G, Nieto, B, Fuentes, M, De la Torre, M, Torres, E, Alonso, A, Velayos, C, Saldaña, T, Escribá, A, Grip, J, Kölegård, R, Sundblad, P, Rooyackers, O, Naser, B, Jaziri, F, Jazia, A, Barghouth, M, Hentati, O, Skouri, W, El Euch, M, Mahfoudhi, M, Turki, S, Abdelghni, K, Abdallah, B, Maha, B, Lorente, M, Włudarczyk, A, Hałek, A, Bargouth, M, Bennasr, M, Abdelghani, K, Abdallah, T, Geenen, I, Parienti, J, Shum, H, King, H, Yan, W, Londoño, J, Cardenas, C, Pedrosa, M, Gubianas, C, Bertolin, C, Batllori, N, Sirvent, J, Mukhopadhyay, A, Chan, H, Kowitlawakul, Y, Remani, D, Leong, C, Henry, C, Puthucheary, Z, Mendsaikhan, N, Begzjav, T, Lundeg, G, Dünser, M, Welsh, S, Guerra, E, Zerpa, M, Zechner, F, Berdaguer, F, Risso Vazquez, A, Masevicius, F, Greaney, D, Magee, A, Fitzpatrick, G, Lugo Cob, R, Tejeda Huezo, B, Cano Oviedo, A, Aydogan, M, Togal, T, Taha, A, Chai, H, Kam, C, Razali, S, Sivasamy, V, Kuan, L, Morales, M, Pires, T, Azevedo, L, Azevedo, L., GIUSSANI, CARLO GIORGIO, SGANZERLA, ERIK PIETRO, and CITERIO, GIUSEPPE
Published: 2016

9. Spatio-temporal modeling of the invasive potential of wild boar—a conflict-prone species—using multi-source citizen science data

Author: Moltke Jordt, A., Lange, Martin, Kramer-Schadt, S., Harm Nielsen, L., Nielsen, S.S., Thulke, Hans-Hermann, Vejre, H., Alban, L., Moltke Jordt, A., Lange, Martin, Kramer-Schadt, S., Harm Nielsen, L., Nielsen, S.S., Thulke, Hans-Hermann, Vejre, H., and Alban, L.
Abstract: Denmark was considered not to have an established population of free-ranging wild boar. Today, sporadic observations of wild boar challenge that view. Due to its reservoir role for economic devastating swine diseases, wild boar represents a potential threat for Denmark’s position as a large pig- and pork-exporting country. This study assessed the prospects of wild boar invasion in Denmark.Multi-source citizen science data of wild boar observations were integrated into a multi-modelling approach linking habitat suitability models with agent-based, spatially-explicit simulations. We tested whether the currently observed presence of wild boar is due to natural immigration across the Danish–German border, or whether it is more likely that wild boar escaped fenced premises. Five observational data sources served as evaluation data: (1) questionnaires sent to all 1625 registered owners of Danish farm land, located in the 60 parishes closest to the border, (2) an online questionnaire, (3) a mobile web-based GPS application, (4) reports in the media or by governmental agencies, and (5) geo-referenced locations of fenced wild boar populations.Data covering 2008–2013 included 195 observations of wild boar, including 16 observations of breeding sows. The data from the Danish Nature Agency and the mailed questionnaires were consistent regarding the location of wild boar observations, while data from the Danish Veterinary and Food Administration, the media and the electronic questionnaires documented individual scattered observations in the rest of Jutland. Most observations were made in the region bordering Germany.It is uncertain whether the relatively few observations represent an established population. Model outcomes suggested that the origin of wild boar in about half of the area with sporadic observations of wild boar could be attributed to spatial expansions from a local Danish population near the border and consisting of wild boar originally of German origin. However, t
Published: 2015

10. A case-control study of risk factors for bovine cysticercosis in Danish cattle herds

Author: Calvo Artavia, Francisco Fernando, Nielsen, Liza Rosenbaum, Dahl, J., Clausen, Dorte Murmann, Graumann, A. M., Alban, L., Calvo Artavia, Francisco Fernando, Nielsen, Liza Rosenbaum, Dahl, J., Clausen, Dorte Murmann, Graumann, A. M., and Alban, L.
Abstract: Bovine cysticercosis (BC) is a zoonotic, parasitic infection in cattle. Under the current EU meat inspection regulation, every single carcass from all bovines above 6 weeks of age is examined for BC. This method is costly and makes more sense in countries with higher number of BC-infected animals than in countries with few lightly infected cases per year. The aim of the present case–control study was to quantify associations between potential herd-level risk factors and BC in Danish cattle herds. Risk factors can be used in the design of a risk-based meat inspection system targeted towards the animals with the highest risk of BC. Cases (n = 77) included herds that hosted at least one animal diagnosed with BC at meat inspection, from 2006 to 2010. Control herds (n = 231) consisted of randomly selected herds that had not hosted any animals diagnosed with BC between 2004 and 2010. The answers from a questionnaire and register data from the Danish Cattle Database were grouped into meaningful variables and used to investigate the risk factors for BC using a multivariable logistic regression model. Case herds were almost three times more likely than control herds to let all or most animals out grazing. Case herds were more than five times more likely than control herds to allow their animals access to risky water sources with sewage treatment plant effluent in proximity. Case herds were also more likely to share machinery or hire contractors than control herds. The risk decreased with increasing herd size probably because the larger herds generally tend to keep cattle indoors in Denmark. The results are useful to guide future data recording that can be supplied by the farmer as food chain information and then be used for differentiated meat inspection in low- and high-risk groups, enabling development of risk-based meat inspection systems., Bovine cysticercosis (BC) is a zoonotic, parasitic infection in cattle. Under the current EU meat inspection regulation, every single carcass from all bovines above 6 weeks of age is examined for BC. This method is costly and makes more sense in countries with higher number of BC-infected animals than in countries with few lightly infected cases per year. The aim of the present case-control study was to quantify associations between potential herd-level risk factors and BC in Danish cattle herds. Risk factors can be used in the design of a risk-based meat inspection system targeted towards the animals with the highest risk of BC. Cases (n = 77) included herds that hosted at least one animal diagnosed with BC at meat inspection, from 2006 to 2010. Control herds (n = 231) consisted of randomly selected herds that had not hosted any animals diagnosed with BC between 2004 and 2010. The answers from a questionnaire and register data from the Danish Cattle Database were grouped into meaningful variables and used to investigate the risk factors for BC using a multivariable logistic regression model. Case herds were almost three times more likely than control herds to let all or most animals out grazing. Case herds were more than five times more likely than control herds to allow their animals access to risky water sources with sewage treatment plant effluent in proximity. Case herds were also more likely to share machinery or hire contractors than control herds. The risk decreased with increasing herd size probably because the larger herds generally tend to keep cattle indoors in Denmark. The results are useful to guide future data recording that can be supplied by the farmer as food chain information and then be used for differentiated meat inspection in low- and high-risk groups, enabling development of risk-based meat inspection systems.
Published: 2013

11. A case-control study of risk factors for bovine cysticercosis in Danish cattle herds

Author: Calvo Artavia, Francisco Fernando, Nielsen, Liza Rosenbaum, Dahl, J., Clausen, Dorte Murmann, Graumann, A. M., Alban, L., Calvo Artavia, Francisco Fernando, Nielsen, Liza Rosenbaum, Dahl, J., Clausen, Dorte Murmann, Graumann, A. M., and Alban, L.
Abstract: Bovine cysticercosis (BC) is a zoonotic, parasitic infection in cattle. Under the current EU meat inspection regulation, every single carcass from all bovines above 6 weeks of age is examined for BC. This method is costly and makes more sense in countries with higher number of BC-infected animals than in countries with few lightly infected cases per year. The aim of the present case–control study was to quantify associations between potential herd-level risk factors and BC in Danish cattle herds. Risk factors can be used in the design of a risk-based meat inspection system targeted towards the animals with the highest risk of BC. Cases (n = 77) included herds that hosted at least one animal diagnosed with BC at meat inspection, from 2006 to 2010. Control herds (n = 231) consisted of randomly selected herds that had not hosted any animals diagnosed with BC between 2004 and 2010. The answers from a questionnaire and register data from the Danish Cattle Database were grouped into meaningful variables and used to investigate the risk factors for BC using a multivariable logistic regression model. Case herds were almost three times more likely than control herds to let all or most animals out grazing. Case herds were more than five times more likely than control herds to allow their animals access to risky water sources with sewage treatment plant effluent in proximity. Case herds were also more likely to share machinery or hire contractors than control herds. The risk decreased with increasing herd size probably because the larger herds generally tend to keep cattle indoors in Denmark. The results are useful to guide future data recording that can be supplied by the farmer as food chain information and then be used for differentiated meat inspection in low- and high-risk groups, enabling development of risk-based meat inspection systems., Bovine cysticercosis (BC) is a zoonotic, parasitic infection in cattle. Under the current EU meat inspection regulation, every single carcass from all bovines above 6 weeks of age is examined for BC. This method is costly and makes more sense in countries with higher number of BC-infected animals than in countries with few lightly infected cases per year. The aim of the present case-control study was to quantify associations between potential herd-level risk factors and BC in Danish cattle herds. Risk factors can be used in the design of a risk-based meat inspection system targeted towards the animals with the highest risk of BC. Cases (n = 77) included herds that hosted at least one animal diagnosed with BC at meat inspection, from 2006 to 2010. Control herds (n = 231) consisted of randomly selected herds that had not hosted any animals diagnosed with BC between 2004 and 2010. The answers from a questionnaire and register data from the Danish Cattle Database were grouped into meaningful variables and used to investigate the risk factors for BC using a multivariable logistic regression model. Case herds were almost three times more likely than control herds to let all or most animals out grazing. Case herds were more than five times more likely than control herds to allow their animals access to risky water sources with sewage treatment plant effluent in proximity. Case herds were also more likely to share machinery or hire contractors than control herds. The risk decreased with increasing herd size probably because the larger herds generally tend to keep cattle indoors in Denmark. The results are useful to guide future data recording that can be supplied by the farmer as food chain information and then be used for differentiated meat inspection in low- and high-risk groups, enabling development of risk-based meat inspection systems.
Published: 2013

12. Epidemiologic and economic evaluation of risk-based meat inspection for bovine cysticercosis in Danish cattle

Author: Calvo Artavia, Francisco Fernando, Nielsen, Liza Rosenbaum, Alban, L., Calvo Artavia, Francisco Fernando, Nielsen, Liza Rosenbaum, and Alban, L.
Abstract: Under the current EU meat inspection regulation, every single carcase from all bovines above 6 weeks of age has to be examined for bovine cysticercosis (BC). This is time-consuming, costly, and is of limited value in countries with low prevalence. The aim of this study was to develop a stochastic simulation model for analysis of tentative risk-based meat inspection systems for BC in Danish cattle with regard to system sensitivity (SSSe), specificity and potential monetary benefits compared to the current system, which has an estimated SSSe of 15%. The relevant risk factors used to construct three alternative scenario trees were identified from previous Danish risk factor studies (1) gender, (2) grazing and (3) access to risky water sources. Thus, females, animals that had been grazing or animals with access to risky water sources were considered high-risk and would be subjected to invasive inspection at meat inspection. All animals in the low-risk groups (i.e. males, non-grazing or no access to risky water sources, respectively) would be subjected to visual inspection only. It was assumed that half of the cattle were slaughtered in abattoirs that would be able to reorganise the work at the slaughterline, allowing them to do with one meat inspector less. All abattoirs would gain on the price of sold uncut beef from the masseter muscles from visually inspected cattle. Under these assumptions, using gender and grazing were preferable due to them having SSSe only slightly lower than the current system, and highest effectiveness ratios, but they had a lower net economic effect (NEE) than the scenario using risky water sources. Using gender to differentiate high and low-risk groups was judged preferable over grazing due to feasibility, because the information is readily available at the slaughter line. The exact total NEE for the cattle sector depends on how many and which of the abattoirs that would be able to reorganise the work at the slaughter line to save money on in
Published: 2013

13. Epidemiologic and economic evaluation of risk-based meat inspection for bovine cysticercosis in Danish cattle

Author: Calvo Artavia, Francisco Fernando, Nielsen, Liza Rosenbaum, Alban, L., Calvo Artavia, Francisco Fernando, Nielsen, Liza Rosenbaum, and Alban, L.
Abstract: Under the current EU meat inspection regulation, every single carcase from all bovines above 6 weeks of age has to be examined for bovine cysticercosis (BC). This is time-consuming, costly, and is of limited value in countries with low prevalence. The aim of this study was to develop a stochastic simulation model for analysis of tentative risk-based meat inspection systems for BC in Danish cattle with regard to system sensitivity (SSSe), specificity and potential monetary benefits compared to the current system, which has an estimated SSSe of 15%. The relevant risk factors used to construct three alternative scenario trees were identified from previous Danish risk factor studies (1) gender, (2) grazing and (3) access to risky water sources. Thus, females, animals that had been grazing or animals with access to risky water sources were considered high-risk and would be subjected to invasive inspection at meat inspection. All animals in the low-risk groups (i.e. males, non-grazing or no access to risky water sources, respectively) would be subjected to visual inspection only. It was assumed that half of the cattle were slaughtered in abattoirs that would be able to reorganise the work at the slaughterline, allowing them to do with one meat inspector less. All abattoirs would gain on the price of sold uncut beef from the masseter muscles from visually inspected cattle. Under these assumptions, using gender and grazing were preferable due to them having SSSe only slightly lower than the current system, and highest effectiveness ratios, but they had a lower net economic effect (NEE) than the scenario using risky water sources. Using gender to differentiate high and low-risk groups was judged preferable over grazing due to feasibility, because the information is readily available at the slaughter line. The exact total NEE for the cattle sector depends on how many and which of the abattoirs that would be able to reorganise the work at the slaughter line to save money on in
Published: 2013

14. Evaluation of the antibacterial residue surveillance programme in Danish pigs using Bayesian methods

Author: Freitas de Matos Baptista, Filipa, Alban, L., Olsen, A. M., Petersen, J. V., Toft, Nils, Freitas de Matos Baptista, Filipa, Alban, L., Olsen, A. M., Petersen, J. V., and Toft, Nils
Abstract: Residues of pharmacological active substances or their metabolites might be found in food products from food-producing animals. Maximum Residue Limits for pharmacological active substances in foodstuffs of animal origin are established to assure high food safety standards. Each year, more than 20,000 samples are analysed for the presence of antibacterial residues in Danish pigs. This corresponds to 0.1% of the size of the slaughter pig population and more than 1% of the sows slaughtered. In this study, a Bayesian model was used to evaluate the Danish surveillance system accuracy and to investigate the impact of a potential risk-based sampling approach to the residue surveillance programme in Danish slaughter pigs. Danish surveillance data from 2005 to 2009 and limited knowledge about true prevalence and test sensitivity and specificity were included in the model. According to the model, the true antibacterial residue prevalence in Danish pigs is very low in both sows (~0.20%) and slaughter pigs (~0.01%). Despite data constraints, the results suggest that the current screening test used in Denmark presents high sensitivity (85-99%) and very high specificity (>99%) for the most relevant antibacterial classes used in Danish pigs. If high-risk slaughter pigs could be identified by taking into account antibacterial use or meat inspection risk factors, a potential risk-based sampling approach to antibacterial residue surveillance in slaughter pigs would allow reducing the sample size substantially, while increasing or maintaining the probability of detection. Hence, the antibacterial residue surveillance programme in Danish pigs would be more cost-effective than today.
Published: 2012

15. Evaluation of the antibacterial residue surveillance programme in Danish pigs using Bayesian methods

Author: Freitas de Matos Baptista, Filipa, Alban, L., Olsen, A. M., Petersen, J. V., Toft, Nils, Freitas de Matos Baptista, Filipa, Alban, L., Olsen, A. M., Petersen, J. V., and Toft, Nils
Abstract: Residues of pharmacological active substances or their metabolites might be found in food products from food-producing animals. Maximum Residue Limits for pharmacological active substances in foodstuffs of animal origin are established to assure high food safety standards. Each year, more than 20,000 samples are analysed for the presence of antibacterial residues in Danish pigs. This corresponds to 0.1% of the size of the slaughter pig population and more than 1% of the sows slaughtered. In this study, a Bayesian model was used to evaluate the Danish surveillance system accuracy and to investigate the impact of a potential risk-based sampling approach to the residue surveillance programme in Danish slaughter pigs. Danish surveillance data from 2005 to 2009 and limited knowledge about true prevalence and test sensitivity and specificity were included in the model. According to the model, the true antibacterial residue prevalence in Danish pigs is very low in both sows (~0.20%) and slaughter pigs (~0.01%). Despite data constraints, the results suggest that the current screening test used in Denmark presents high sensitivity (85-99%) and very high specificity (>99%) for the most relevant antibacterial classes used in Danish pigs. If high-risk slaughter pigs could be identified by taking into account antibacterial use or meat inspection risk factors, a potential risk-based sampling approach to antibacterial residue surveillance in slaughter pigs would allow reducing the sample size substantially, while increasing or maintaining the probability of detection. Hence, the antibacterial residue surveillance programme in Danish pigs would be more cost-effective than today.
Published: 2012

16. Towards a standardised surveillance for Trichinella in the European Union

Author: Alban, L., Pozio, E., Boes, J., Boireau, P., Boué, F., Claes, M., Cook, A.J.C., Dorny, P., Enemark, Heidi L., Giessen, J. van der, Hunt, K.R., Howell, M., Kirjusina, M., Nöckler, K., Rossi, P., Smith, G.C., Snow, L., Taylor, M., Theodoropoulos, G., Vallée, I., Viera-Pinto, M.M., Zimmer, I.A., Alban, L., Pozio, E., Boes, J., Boireau, P., Boué, F., Claes, M., Cook, A.J.C., Dorny, P., Enemark, Heidi L., Giessen, J. van der, Hunt, K.R., Howell, M., Kirjusina, M., Nöckler, K., Rossi, P., Smith, G.C., Snow, L., Taylor, M., Theodoropoulos, G., Vallée, I., Viera-Pinto, M.M., and Zimmer, I.A.
Abstract: Each year, more than 167 million pigs in the European Union (EU) are tested for Trichinella spp. under the current meat hygiene regulations. This imposes large economic costs on countries, yet the vast majority of these pigs test negative and the public health risk in many countries is therefore considered very low. This work reviewed the current Trichinella status across the EU as well as the national level of monitoring and reporting. It also reviewed which animal species were affected by Trichinella and in which species it should be surveyed. This information was used to design a cost-effective surveillance programme that enables a standardised monitoring approach within the EU. The proposed surveillance programme relies on identifying sub-populations of animals with a distinct risk. Low-risk pigs are finisher pigs that originate from so-called controlled housing. All other pigs are considered high-risk pigs. Controlled housing is identified by the application of a specific list of management and husbandry practices. We suggest that member states (MS) be categorised into three classes based on the confidence that Trichinella can be considered absent, in the specified sub-population of pigs above a specified design prevalence which we set to 1 per million pigs. A simple and transparent method is proposed to estimate this confidence, based on the sensitivity of the surveillance system, taking into account the sensitivity of testing and the design prevalence. The probability of detecting a positive case, if present, must be high (>95 or >99%) to ensure that there is a low or negligible risk of transmission to humans through the food chain. In MS where the probability of a positive pig is demonstrated to be negligible, testing of fattening pigs from a sub-population consisting of pigs from controlled housing can be considered unnecessary. Furthermore, reduced testing of finishers from the sub-population consisting of pigs from non-co
Published: 2011

17. Management practices reducing the test-prevalence of paratuberculosis in Danish dairy herds

Author: Alban, L., Kelly, L.A., Nielsen, Søren Saxmose, Toft, Nils, Alban, L., Kelly, L.A., Nielsen, Søren Saxmose, and Toft, Nils
Published: 2010

18. Spatial modelling of the between-herd infection dynamics of bovine virus diarrhoea virus (BVDV) in dairy herds in Denmark

Author: Ersbøll, Annette Kjær, Ersbøll, Bjarne Kjær, Houe, Hans, Alban, L., Kjeldsen, A.M., Ersbøll, Annette Kjær, Ersbøll, Bjarne Kjær, Houe, Hans, Alban, L., and Kjeldsen, A.M.
Published: 2010

19. Use of herd information for predicting Salmonella status in pig herds

Author: Freitas de Matos Baptista, Filipa, Alban, L., Nielsen, Liza Rosenbaum, Domingos, I., Pomba, C., Almeida, V., Freitas de Matos Baptista, Filipa, Alban, L., Nielsen, Liza Rosenbaum, Domingos, I., Pomba, C., and Almeida, V.
Published: 2010

20. Management practices reducing the test-prevalence of paratuberculosis in Danish dairy herds

Author: Alban, L., Kelly, L.A., Nielsen, Søren Saxmose, Toft, Nils, Alban, L., Kelly, L.A., Nielsen, Søren Saxmose, and Toft, Nils
Published: 2010

21. Spatial modelling of the between-herd infection dynamics of bovine virus diarrhoea virus (BVDV) in dairy herds in Denmark

Author: Ersbøll, Annette Kjær, Ersbøll, Bjarne Kjær, Houe, Hans, Alban, L., Kjeldsen, A.M., Ersbøll, Annette Kjær, Ersbøll, Bjarne Kjær, Houe, Hans, Alban, L., and Kjeldsen, A.M.
Published: 2010

22. Use of herd information for predicting Salmonella status in pig herds

Author: Freitas de Matos Baptista, Filipa, Alban, L., Nielsen, Liza Rosenbaum, Domingos, I., Pomba, C., Almeida, V., Freitas de Matos Baptista, Filipa, Alban, L., Nielsen, Liza Rosenbaum, Domingos, I., Pomba, C., and Almeida, V.
Published: 2010

23. Comparing the epidemiological and economic effects of control strategies against classical swine fever in Denmark

Author: Boklund, A., Toft, N., Alban, L., Uttenthal, Å., Boklund, A., Toft, N., Alban, L., and Uttenthal, Å.
Abstract: In 2006, total Danish pork exports were valued at €3.8 billion, corresponding to approximately 5% of the total Danish exports, and an outbreak of a notifiable disease would have dramatic consequences for the agricultural sector in Denmark. Several outbreaks of classical swine fever (CSF) have occurred in Europe within the last decade, and different control strategies have been suggested. The objective of this study was to simulate the epidemiological and economic consequences of such control strategies in a CSF epidemic under Danish conditions with respect to herd demographics and geography and to investigate the effect of extra biosecurity measures on farms. We used InterSpread Plus to model the effect of nine different control strategies: the minimum measures required by the EU plus depopulation of contact herds (EUplus), extra depopulation of neighbouring herds, extra surveillance within the protection and surveillance zones, extra biosecurity in SPF herds-or in all herds, vaccination of all pigs in the 1 or 2 km zones using live vaccine as a protective measure (vaccination-to-kill), vaccination of all weaners and finishers in the 1 or 2 km zones using an E2 marker vaccine as a suppressive measure (vaccination-to-live). Each epidemic was simulated to start in four different index herds: production herds located in low, medium and high pig density areas, respectively; and a nucleus herd in an area of high pig density. For each control strategy and index case, we calculated the size and duration of the epidemic, the number of depopulated and/or vaccinated herds and animals, the control costs borne by the public and the pig industry, respectively, as well as the loss of exports associated with the epidemic. The simulations showed that the EUplus strategy is the most effective of the evaluated strategies with respect to limiting the size, duration and cost of the epidemic, regardless of the index case. However, regarding the number of slaughtered animals, the vacc
Published: 2009

24. Factors affecting persistence of high Salmonella serology in Danish pig herds

Author: Freitas de Matos Baptista, Filipa, Alban, L., Ersbøll, Annette Kjær, Nielsen, Liza Rosenbaum, Freitas de Matos Baptista, Filipa, Alban, L., Ersbøll, Annette Kjær, and Nielsen, Liza Rosenbaum
Published: 2009

25. Comparing the epidemiological and economic effects of control strategies against classical swine fever in Denmark

Author: Boklund, A., Toft, N., Alban, L., Uttenthal, Å., Boklund, A., Toft, N., Alban, L., and Uttenthal, Å.
Abstract: In 2006, total Danish pork exports were valued at €3.8 billion, corresponding to approximately 5% of the total Danish exports, and an outbreak of a notifiable disease would have dramatic consequences for the agricultural sector in Denmark. Several outbreaks of classical swine fever (CSF) have occurred in Europe within the last decade, and different control strategies have been suggested. The objective of this study was to simulate the epidemiological and economic consequences of such control strategies in a CSF epidemic under Danish conditions with respect to herd demographics and geography and to investigate the effect of extra biosecurity measures on farms. We used InterSpread Plus to model the effect of nine different control strategies: the minimum measures required by the EU plus depopulation of contact herds (EUplus), extra depopulation of neighbouring herds, extra surveillance within the protection and surveillance zones, extra biosecurity in SPF herds-or in all herds, vaccination of all pigs in the 1 or 2 km zones using live vaccine as a protective measure (vaccination-to-kill), vaccination of all weaners and finishers in the 1 or 2 km zones using an E2 marker vaccine as a suppressive measure (vaccination-to-live). Each epidemic was simulated to start in four different index herds: production herds located in low, medium and high pig density areas, respectively; and a nucleus herd in an area of high pig density. For each control strategy and index case, we calculated the size and duration of the epidemic, the number of depopulated and/or vaccinated herds and animals, the control costs borne by the public and the pig industry, respectively, as well as the loss of exports associated with the epidemic. The simulations showed that the EUplus strategy is the most effective of the evaluated strategies with respect to limiting the size, duration and cost of the epidemic, regardless of the index case. However, regarding the number of slaughtered animals, the vacc
Published: 2009

26. Factors affecting persistence of high Salmonella serology in Danish pig herds

Author: Freitas de Matos Baptista, Filipa, Alban, L., Ersbøll, Annette Kjær, Nielsen, Liza Rosenbaum, Freitas de Matos Baptista, Filipa, Alban, L., Ersbøll, Annette Kjær, and Nielsen, Liza Rosenbaum
Published: 2009

27. The use of critical reviews and meta-analysis of diagnostic test evaluations - illustrated by diagnostic tests for paratuberculosis

Author: Peeler, E.J., Alban, L., Russell, A., Toft, Nils, Nielsen, Søren Saxmose, Peeler, E.J., Alban, L., Russell, A., Toft, Nils, and Nielsen, Søren Saxmose
Published: 2008

28. The use of critical reviews and meta-analysis of diagnostic test evaluations - illustrated by diagnostic tests for paratuberculosis

Author: Peeler, E.J., Alban, L., Russell, A., Toft, Nils, Nielsen, Søren Saxmose, Peeler, E.J., Alban, L., Russell, A., Toft, Nils, and Nielsen, Søren Saxmose
Published: 2008

29. Experimental and clinical radiofrequency ablation: Proposal for standardized description of coagulation size and geometry

Author: UCL - MD/RAIM - Département de radiologie et d'imagerie médicale, UCL - MD/CHIR - Département de chirurgie, UCL - (MGD) Service de chirurgie, UCL - (MGD) Service de radiologie - résonance magnétique, Mulier, Stefaan, Ni, Yicheng, Frich, Lars, Burdio, Fernando, Denys, Alban L., De Wispelaere, Jean-François, Dupas, Benoit, Habib, Nagy, Hoey, Michael, Jansen, Maarten C., Lacrosse, Marc, Leveillee, Raymond, Miao, Yi, Mulier, Peter, Mutter, Didier, Ng, Kelvin K., Santambrogio, Roberto, Stippel, Dirk, Tamaki, Katsuyoshi, van Gulik, Thomas M., Marchal, Guy, Michel, Luc, UCL - MD/RAIM - Département de radiologie et d'imagerie médicale, UCL - MD/CHIR - Département de chirurgie, UCL - (MGD) Service de chirurgie, UCL - (MGD) Service de radiologie - résonance magnétique, Mulier, Stefaan, Ni, Yicheng, Frich, Lars, Burdio, Fernando, Denys, Alban L., De Wispelaere, Jean-François, Dupas, Benoit, Habib, Nagy, Hoey, Michael, Jansen, Maarten C., Lacrosse, Marc, Leveillee, Raymond, Miao, Yi, Mulier, Peter, Mutter, Didier, Ng, Kelvin K., Santambrogio, Roberto, Stippel, Dirk, Tamaki, Katsuyoshi, van Gulik, Thomas M., Marchal, Guy, and Michel, Luc
Abstract: Background: Radiofrequency (RF) ablation is used to obtain local control of unresectable tumors in liver, kidney, prostate, and other organs. Accurate data on expected size and geometry of coagulation zones are essential for physicians to prevent collateral damage and local tumor recurrence. The aim of this study was to develop a standardized terminology to describe the size and geometry of these zones for experimental and clinical RF. Methods: In a first step, the essential geometric parameters to accurately describe the coagulation zones and the spatial relationship between the coagulation zones and the electrodes were defined. In a second step, standard terms were assigned to each parameter. Results: The proposed terms for single-electrode RF ablation include axial diameter, front margin, coagulation center, maximal and minimal radius, maximal and minimal transverse diameter, ellipticity index, and regularity index. In addition a subjective description of the general shape and regularity is recommended. Conclusions: Adoption of the proposed standardized description method may help to fill in the many gaps in our current knowledge of the size and geometry of RF coagulation zones.
Published: 2007

30. Classical swine fever and wild boar in Denmark: A risk analysis

Author: Alban, L., Andersen, M.M., Asferg, T., Boklund, A., Fernández, Néstor, Goldbach, S.G., Greiner, M., Hojgaard, A., Dramer-Schadt, S., Stockmarr, A., Thulke, H.H., Uttenthal, A., Ydesen, B., Alban, L., Andersen, M.M., Asferg, T., Boklund, A., Fernández, Néstor, Goldbach, S.G., Greiner, M., Hojgaard, A., Dramer-Schadt, S., Stockmarr, A., Thulke, H.H., Uttenthal, A., and Ydesen, B.
Abstract: Currently there is no established population of free-range wild boar in Denmark. In order to preserve nature and manage national biodiversity, Danish wildlife organisations have presented the idea that the wild boar should be reintroduced into Denmark. There is evidence that wild boar are involved in CSF outbreaks in pigs in Europe. For that reason Danish pig farmers are concerned about the risk associated with such an introduction. The economic consequences of an introduction of CSF would be devastating, not only for the individual farmer, but also for national economies. Denmark, which is the world’s largest net exporter of pork and exports around 84% of its pork production, would be particularly vulnerable. In 2002, Denmark exported pork in the order of 26 bDKK. Therefore, a temporary ban on export, which would follow an introduction of CSFV, would be detrimental for the pig industry.
Published: 2005

31. Survival of Escherichia coli and Salmonella typhimurium in slurry applied to clay soil on a Danish swine farm

Author: Boes, J., Alban, L., Bagger, J., Møgelmose, V., Baggesen, D.L., Olsen, John Elmerdahl, Boes, J., Alban, L., Bagger, J., Møgelmose, V., Baggesen, D.L., and Olsen, John Elmerdahl
Abstract: Udgivelsesdato: JUL 12
Published: 2005

32. Survival of Escherichia coli and Salmonella typhimurium in slurry applied to clay soil on a Danish swine farm

Author: Boes, J., Alban, L., Bagger, J., Møgelmose, V., Baggesen, D.L., Olsen, John Elmerdahl, Boes, J., Alban, L., Bagger, J., Møgelmose, V., Baggesen, D.L., and Olsen, John Elmerdahl
Abstract: Udgivelsesdato: JUL 12
Published: 2005

33. Spatial statistical methods for estimating regions with increased risk of BVDV infection in Denmark

Author: Durr, P.A., Martin, S.W., Ersbøll, Annette Kjær, Toft, Nils, Ersbøll, B.K., Houe, Hans, Alban, L., Stryhn, H., Kjeldsen, A.M., Durr, P.A., Martin, S.W., Ersbøll, Annette Kjær, Toft, Nils, Ersbøll, B.K., Houe, Hans, Alban, L., Stryhn, H., and Kjeldsen, A.M.
Published: 2004

34. Biosecurity in 116 Danish fattening swineherds:descriptive results and factor analysis

Author: Boklund, A., Alban, L., Mortensen, S., Houe, Hans, Boklund, A., Alban, L., Mortensen, S., and Houe, Hans
Published: 2004

35. Spatial statistical methods for estimating regions with increased risk of BVDV infection in Denmark

Author: Durr, P.A., Martin, S.W., Ersbøll, Annette Kjær, Toft, Nils, Ersbøll, B.K., Houe, Hans, Alban, L., Stryhn, H., Kjeldsen, A.M., Durr, P.A., Martin, S.W., Ersbøll, Annette Kjær, Toft, Nils, Ersbøll, B.K., Houe, Hans, Alban, L., Stryhn, H., and Kjeldsen, A.M.
Published: 2004

36. Biosecurity in 116 Danish fattening swineherds:descriptive results and factor analysis

Author: Boklund, A., Alban, L., Mortensen, S., Houe, Hans, Boklund, A., Alban, L., Mortensen, S., and Houe, Hans
Published: 2004

37. Biosecurity in 116 Danish fattening swineherds: descriptive results and factor analysis

Author: Boklund, Anette, Alban, L., Mortensen, Sten, Houe, H., Boklund, Anette, Alban, L., Mortensen, Sten, and Houe, H.
Abstract: Biosecurity measures are important for the herd's protection against diseases and also to provide nationwide protection against the introduction of exotic diseases. In this paper, we describe the farmers’ choices and routines regarding biosecurity in Danish fattening herds.Overall, 116 Danish swine fattening herds in three areas of different pig density were interviewed.Of these herds, 78% purchased weaners from one sow herd only, whereas 10% purchased from >5 sow herds during 1 year. Large herds (>500 finishers) purchased weaners more often than smaller herds (≤500 finishers). Only two swine producers purchased weaners from a market. Almost all herds (95%) received weaners from one sow herd at one time, and only one herd received from >5 sow herds in one batch. Twenty-one percent did not use an effective barrier between the loading area and the stables when delivering pigs for slaughter. Entry rooms (in which clothing and boots are changed) were common at the farm, and the numbers of visitors were generally low ( 3.10). A site scoring high on factor 1 was a large SPF herd, which received weaners from a single source, had biosecurity requirements for the transport vehicles, and had a high level of biosecurity for visitors. A site scoring high on factor 2 was a multi-site farm, which had personnel working on more than one of the sites, only received weaners from one sow herd, had delivering herds placed close to the participating site, and transported animals themselves. A site scoring high on factor 3 was a site which hired commercial transport for slaughter, was situated far from the abattoir and had a high level of biosecurity when loading pigs. A production site scoring high on factor 4 was a large site, which used all-in/all-out management, washed and disinfected between each group, and purchased many weaners.
Published: 2004

38. Risk factors for metritis in Danish dairy cows

Author: Bruun, J., Ersbøll, A. K., Alban, L, Bruun, J., Ersbøll, A. K., and Alban, L
Published: 2002

39. Risk factors for metritis in Danish dairy cows

Author: Bruun, J., Ersbøll, A. K., Alban, L, Bruun, J., Ersbøll, A. K., and Alban, L
Published: 2002

40. Animal Health and Welfare during transition to organic dairy production: problems, priorities and perspectives

Author: Vaarst, M., Alban, L., Mogensen, L, Thamsborg, S.M., Kristensen, E.S., Vaarst, M., Alban, L., Mogensen, L, Thamsborg, S.M., and Kristensen, E.S.
Abstract: During the past few years, organic dairy farming has grown dramatically in Denmark. Consequently, an increasing number of people are encountering this method of production for the first time. Amongst these, many veterinarians have suddenly had to deal with organic herds in their home district, and, meeting examples of poor animal welfare, they have recently started to express some concerns. Against this background, a so-called “Synthesis of Knowledge” project was initiated to examine the health and welfare of dairy cattle and the use of medication in the transition to organic production. The aim of the project was to investigate associated problems from the point of view of the dairy herd. Based on qualitative research interviews with vets and agricultural advisors, as well as focus group interviews with farmers who had recently converted from conventional to organic farming, an expert panel attempted to identify problem areas and possible solutions. The problems related to (a) the adjustment to new and unknown practices, (b) poor management in general, and (c) inappropriate legislation for organic farming. One problem area was the rearing of dairy calves, particularly with regard to the establishment of post partum relationships between cow and calf, group housing, and the grazing of young animals. A “natural life” was identified as being fundamental to organic animal husbandry. In terms of animal welfare, this concept can be understood as a way of living in which the calf is allowed to express its natural behavior and satisfy its natural needs. Essentially, the conditions needed for good calf welfare require the compatibility and interplay of elements from “nature” (the natural life; including opportunities to satisfy natural needs) and “culture” (farmer management skills; exercise of care). These elements should be balanced to ensure animal welfare in organic herds.
Published: 2001

41. Animal Health and Welfare during transition to organic dairy production: problems, priorities and perspectives

Author: Vaarst, M., Alban, L., Mogensen, L, Thamsborg, S.M., Kristensen, E.S., Vaarst, M., Alban, L., Mogensen, L, Thamsborg, S.M., and Kristensen, E.S.
Abstract: During the past few years, organic dairy farming has grown dramatically in Denmark. Consequently, an increasing number of people are encountering this method of production for the first time. Amongst these, many veterinarians have suddenly had to deal with organic herds in their home district, and, meeting examples of poor animal welfare, they have recently started to express some concerns. Against this background, a so-called “Synthesis of Knowledge” project was initiated to examine the health and welfare of dairy cattle and the use of medication in the transition to organic production. The aim of the project was to investigate associated problems from the point of view of the dairy herd. Based on qualitative research interviews with vets and agricultural advisors, as well as focus group interviews with farmers who had recently converted from conventional to organic farming, an expert panel attempted to identify problem areas and possible solutions. The problems related to (a) the adjustment to new and unknown practices, (b) poor management in general, and (c) inappropriate legislation for organic farming. One problem area was the rearing of dairy calves, particularly with regard to the establishment of post partum relationships between cow and calf, group housing, and the grazing of young animals. A “natural life” was identified as being fundamental to organic animal husbandry. In terms of animal welfare, this concept can be understood as a way of living in which the calf is allowed to express its natural behavior and satisfy its natural needs. Essentially, the conditions needed for good calf welfare require the compatibility and interplay of elements from “nature” (the natural life; including opportunities to satisfy natural needs) and “culture” (farmer management skills; exercise of care). These elements should be balanced to ensure animal welfare in organic herds.
Published: 2001

42. Animal Health and Welfare during transition to organic dairy production: problems, priorities and perspectives

Author: Vaarst, M., Alban, L., Mogensen, L, Thamsborg, S.M., Kristensen, E.S., Vaarst, M., Alban, L., Mogensen, L, Thamsborg, S.M., and Kristensen, E.S.
Abstract: During the past few years, organic dairy farming has grown dramatically in Denmark. Consequently, an increasing number of people are encountering this method of production for the first time. Amongst these, many veterinarians have suddenly had to deal with organic herds in their home district, and, meeting examples of poor animal welfare, they have recently started to express some concerns. Against this background, a so-called “Synthesis of Knowledge” project was initiated to examine the health and welfare of dairy cattle and the use of medication in the transition to organic production. The aim of the project was to investigate associated problems from the point of view of the dairy herd. Based on qualitative research interviews with vets and agricultural advisors, as well as focus group interviews with farmers who had recently converted from conventional to organic farming, an expert panel attempted to identify problem areas and possible solutions. The problems related to (a) the adjustment to new and unknown practices, (b) poor management in general, and (c) inappropriate legislation for organic farming. One problem area was the rearing of dairy calves, particularly with regard to the establishment of post partum relationships between cow and calf, group housing, and the grazing of young animals. A “natural life” was identified as being fundamental to organic animal husbandry. In terms of animal welfare, this concept can be understood as a way of living in which the calf is allowed to express its natural behavior and satisfy its natural needs. Essentially, the conditions needed for good calf welfare require the compatibility and interplay of elements from “nature” (the natural life; including opportunities to satisfy natural needs) and “culture” (farmer management skills; exercise of care). These elements should be balanced to ensure animal welfare in organic herds.
Published: 2001

43. Animal Health and Welfare during transition to organic dairy production: problems, priorities and perspectives

Author: Vaarst, M., Alban, L., Mogensen, L, Thamsborg, S.M., Kristensen, E.S., Vaarst, M., Alban, L., Mogensen, L, Thamsborg, S.M., and Kristensen, E.S.
Abstract: During the past few years, organic dairy farming has grown dramatically in Denmark. Consequently, an increasing number of people are encountering this method of production for the first time. Amongst these, many veterinarians have suddenly had to deal with organic herds in their home district, and, meeting examples of poor animal welfare, they have recently started to express some concerns. Against this background, a so-called “Synthesis of Knowledge” project was initiated to examine the health and welfare of dairy cattle and the use of medication in the transition to organic production. The aim of the project was to investigate associated problems from the point of view of the dairy herd. Based on qualitative research interviews with vets and agricultural advisors, as well as focus group interviews with farmers who had recently converted from conventional to organic farming, an expert panel attempted to identify problem areas and possible solutions. The problems related to (a) the adjustment to new and unknown practices, (b) poor management in general, and (c) inappropriate legislation for organic farming. One problem area was the rearing of dairy calves, particularly with regard to the establishment of post partum relationships between cow and calf, group housing, and the grazing of young animals. A “natural life” was identified as being fundamental to organic animal husbandry. In terms of animal welfare, this concept can be understood as a way of living in which the calf is allowed to express its natural behavior and satisfy its natural needs. Essentially, the conditions needed for good calf welfare require the compatibility and interplay of elements from “nature” (the natural life; including opportunities to satisfy natural needs) and “culture” (farmer management skills; exercise of care). These elements should be balanced to ensure animal welfare in organic herds.
Published: 2001

44. Estimating transfer of bovine virus-diarrhoea virus in Danish cattle by use of register data

Author: Alban, L., Stryhn, H., Kjeldsen, A. M., Ersbøll, A. K., Skjøth, F., Christensen, J., Bitsch, V., Chriél, M., Strøger, U., Alban, L., Stryhn, H., Kjeldsen, A. M., Ersbøll, A. K., Skjøth, F., Christensen, J., Bitsch, V., Chriél, M., and Strøger, U.
Published: 2001

45. Health and welfare in danish dairy cattle in the transition to organic production: problems, priorities and perspectives

Author: Vaarst, M., Alban, L., Mogensen, L., Thamsborg, S.M., Kristensen, E.S., Vaarst, M., Alban, L., Mogensen, L., Thamsborg, S.M., and Kristensen, E.S.
Published: 2001

46. Animal health and welfare during conversion to organic dairy production:problems, priorities and perspectives

Author: Vaarst, M., Alban, L., Mogensen, L., Thamsborg, Stig Milan, Kristensen, E. S., Vaarst, M., Alban, L., Mogensen, L., Thamsborg, Stig Milan, and Kristensen, E. S.
Published: 2001

47. Validation of welfare assessment methods at herd level:an example

Author: Alban, L., Ersbøll, A. K., Bennedsgaard, T. W., Fraas Johnsen, P., Alban, L., Ersbøll, A. K., Bennedsgaard, T. W., and Fraas Johnsen, P.
Published: 2001

48. The welfare impact of increased gavaging doses in rats

Author: Alban, L., Dahl, P. J., Kornerup Hansen, A., Hejgaard, K. C., Lundorff Jensen, A., Kragh, M., Thomsen, P., Stensgaard, P., Alban, L., Dahl, P. J., Kornerup Hansen, A., Hejgaard, K. C., Lundorff Jensen, A., Kragh, M., Thomsen, P., and Stensgaard, P.
Published: 2001

49. Animal Health and Welfare during transition to organic dairy production: problems, priorities and perspectives

Author: Vaarst, M., Alban, L., Mogensen, L, Thamsborg, S.M., Kristensen, E.S., Vaarst, M., Alban, L., Mogensen, L, Thamsborg, S.M., and Kristensen, E.S.
Abstract: During the past few years, organic dairy farming has grown dramatically in Denmark. Consequently, an increasing number of people are encountering this method of production for the first time. Amongst these, many veterinarians have suddenly had to deal with organic herds in their home district, and, meeting examples of poor animal welfare, they have recently started to express some concerns. Against this background, a so-called “Synthesis of Knowledge” project was initiated to examine the health and welfare of dairy cattle and the use of medication in the transition to organic production. The aim of the project was to investigate associated problems from the point of view of the dairy herd. Based on qualitative research interviews with vets and agricultural advisors, as well as focus group interviews with farmers who had recently converted from conventional to organic farming, an expert panel attempted to identify problem areas and possible solutions. The problems related to (a) the adjustment to new and unknown practices, (b) poor management in general, and (c) inappropriate legislation for organic farming. One problem area was the rearing of dairy calves, particularly with regard to the establishment of post partum relationships between cow and calf, group housing, and the grazing of young animals. A “natural life” was identified as being fundamental to organic animal husbandry. In terms of animal welfare, this concept can be understood as a way of living in which the calf is allowed to express its natural behavior and satisfy its natural needs. Essentially, the conditions needed for good calf welfare require the compatibility and interplay of elements from “nature” (the natural life; including opportunities to satisfy natural needs) and “culture” (farmer management skills; exercise of care). These elements should be balanced to ensure animal welfare in organic herds.
Published: 2001

50. Animal Health and Welfare during transition to organic dairy production: problems, priorities and perspectives

Author: Vaarst, M., Alban, L., Mogensen, L, Thamsborg, S.M., Kristensen, E.S., Vaarst, M., Alban, L., Mogensen, L, Thamsborg, S.M., and Kristensen, E.S.
Abstract: During the past few years, organic dairy farming has grown dramatically in Denmark. Consequently, an increasing number of people are encountering this method of production for the first time. Amongst these, many veterinarians have suddenly had to deal with organic herds in their home district, and, meeting examples of poor animal welfare, they have recently started to express some concerns. Against this background, a so-called “Synthesis of Knowledge” project was initiated to examine the health and welfare of dairy cattle and the use of medication in the transition to organic production. The aim of the project was to investigate associated problems from the point of view of the dairy herd. Based on qualitative research interviews with vets and agricultural advisors, as well as focus group interviews with farmers who had recently converted from conventional to organic farming, an expert panel attempted to identify problem areas and possible solutions. The problems related to (a) the adjustment to new and unknown practices, (b) poor management in general, and (c) inappropriate legislation for organic farming. One problem area was the rearing of dairy calves, particularly with regard to the establishment of post partum relationships between cow and calf, group housing, and the grazing of young animals. A “natural life” was identified as being fundamental to organic animal husbandry. In terms of animal welfare, this concept can be understood as a way of living in which the calf is allowed to express its natural behavior and satisfy its natural needs. Essentially, the conditions needed for good calf welfare require the compatibility and interplay of elements from “nature” (the natural life; including opportunities to satisfy natural needs) and “culture” (farmer management skills; exercise of care). These elements should be balanced to ensure animal welfare in organic herds.
Published: 2001

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