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2 results on '"Cai LM"'

1. Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase

Author

Ronen, Sabrina, Ronen, Sabrina, Pieper, Russell, Phillips, Joanna, Izquierdo-Garcia, JL, Cai, LM, Chaumeil, MM, Eriksson, P, Robinson, AE, Pieper, RO, Phillips, JJ, Ronen, SM, Ronen, Sabrina, Ronen, Sabrina, Pieper, Russell, Phillips, Joanna, Izquierdo-Garcia, JL, Cai, LM, Chaumeil, MM, Eriksson, P, Robinson, AE, Pieper, RO, Phillips, JJ, and Ronen, SM

Abstract

Background: Over 70% of low-grade gliomas carry a heterozygous R132H mutation in the gene coding for isocitrate dehydrogenase 1 (IDH1). This confers the enzyme with the novel ability to convert a-ketoglutarate to 2-hydroxyglutarate, ultimately leading to t

Published
2014

2. Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase

Author

Ronen, Sabrina, Ronen, Sabrina, Pieper, Russell, Phillips, Joanna, Izquierdo-Garcia, JL, Cai, LM, Chaumeil, MM, Eriksson, P, Robinson, AE, Pieper, RO, Phillips, JJ, Ronen, SM, Ronen, Sabrina, Ronen, Sabrina, Pieper, Russell, Phillips, Joanna, Izquierdo-Garcia, JL, Cai, LM, Chaumeil, MM, Eriksson, P, Robinson, AE, Pieper, RO, Phillips, JJ, and Ronen, SM

Abstract

Background: Over 70% of low-grade gliomas carry a heterozygous R132H mutation in the gene coding for isocitrate dehydrogenase 1 (IDH1). This confers the enzyme with the novel ability to convert a-ketoglutarate to 2-hydroxyglutarate, ultimately leading to t

Published
2014

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