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In this retrospective comparative case series at a teaching hospital, we reviewed adult patients with rhegmatogenous retinal detachment who underwent scleral buckling surgery with external drainage of subretinal fluid performed before versus after placement of the scleral buckle. Eight eyes in each group were roughly matched for age, sex, baseline visual acuity (VA), and detachment characteristics. The complication rate was 0% for the "before" group and 37% for the "after" group (p = 0.100). In the "after" group, two eyes (25%) developed iatrogenic retinal holes and one eye (12%) developed self-limited subretinal hemorrhage during external needle drainage. The duration of surgery was significantly shorter for the "before" group (mean 89 ± 16 min) compared to the "after" group (118 ± 20 min) (p = 0.008). The primary anatomic success rate was 100% for the "before" group and 75% for the "after" group (p = 0.233). Final VA was not significantly different between the groups or from baseline. In conclusion, while limited by our small sample size, this pilot study suggests that drainage of subretinal fluid before scleral buckle placement may be safer and more efficient compared to draining after buckle placement. Initial drainage may facilitate retinochoroid apposition to allow targeted cryopexy and precise buckle placement.

BackgroundNephroureterectomy remains the gold standard treatment for upper tract urothelial carcinoma (UTUC). Considering the high risk of developing renal function impairment after surgery, the rationale for nephron sparing approaches in treatment of UTUC has been raised. In this case, renal cryoablation was able to achieve successful oncologic control while preserving renal function during 5 years of follow up without intraoperative or post operative complications.Case presentationA 79 year old male presents after three months of macroscopic hematuria. Imaging revealed a 3.6 × 3.1 × 2.7 cm endophytic mass in the interpolar region of the left kidney and an atrophic right kidney. After weighing the lesion's location with the patient's of complex medical history, he was counselled to undergo a minimally invasive percutaneous cryoablation as treatment for his solitary renal mass. A diagnostic dilemma was encountered as imaging suggested a diagnosis of renal cell carcinoma. However, the pre-ablation biopsy established an alternative diagnosis, revealing UTUC. Percutaneous cryoablation became an unorthodox treatment modality for the endophytic component of his UTUC followed by retrograde ureteroscopic laser fulguration. The patient was followed in 3 months, 6 months, then annually with cross sectional imaging by MRI, cystoscopy, urine cytology and renal function testing. After five years of follow-up, the patient did not encountered recurrence of UTUC or deterioration in renal function, thereby maintaining a stable eGFR.ConclusionAlthough evidence for nephron-sparing modalities for UTUC is mounting in recent literature, limited data still exists on cryotherapy as a line of treatment for urothelial carcinoma. We report successful management of a low-grade UTUC using cryoablation with the crucial aid of an initial renal biopsy and long-term follow-up. Our results provide insight into the role of cryoablation as a nephron-sparing approach for UTUC.

This study aims to analyze the influence of the application of cryotherapy on shoulder proprioception in badminton athletes. Thirty federated badminton athletes were included in this study, all of whom belonged to three of the teams currently competing in national competitions (Portugal). Their mean ages were 21.00 ± 5.60 years, and their experience in the modality was 8.40 ± 6.93 years. They practiced in an average of 2.93 ± 1.26 training sessions per week. All of them used their right hand to hold the racket. Each participant’s dominant shoulder joint position and force senses were evaluated for four consecutive time points through the isokinetic dynamometer Biodex System 3. The experimental procedure consisted of applying ice for 15 min and the control procedure consisted of no therapeutic intervention. The proprioception outcomes were expressed using the absolute error, relative error, and variable error. All statistical analysis was performed using PASW Statistics 18 software (IBM-SPSS Statistics). There were no statistically significant changes in the joint position and force senses after the intervention, as well as during the subsequent 30 min. We conclude that, after this cryotherapy technique, there is no increased risk of injury associated with a proprioception deficit that prevents athletes from immediately returning to badminton practice.

Introduction. Cervical cancer is a relevant public health problem for low- and middleincome countries. Follow-up of positive-screened women and compliance with treatment of precancerous lesions are major challenges for these settings.Objective. To evaluate the efficacy of cryotherapy delivered by nurses for cervical intraepithelial neoplasia (CIN).Materials and methods. Direct visual inspection with acetic acid and lugol iodine (VIAVILI), and colposcopy/biopsy were performed on women 25 to 59 years old, residents of low-income areas in Bogotá, Colombia. Trained nurses offered immediate cryotherapy to every woman with positive visual inspection. Colposcopy/biopsy was performed before treatment and at a 12-month follow-up. The effectiveness was measured as cure (outcome: no-lesion) and regression (outcome: CIN1) rates of CIN2/3 using colposcopic and histological verification.Results. A group of 4.957 women with VIA/VILI was valuated. In total, 499 were screen positive and 472 accepted immediate treatment. A total of 365 women (11 CIN2/3) received cryotherapy by nurses. Cure rate was 72% (95%CI: 39%-94%) and 40% (95%CI: 22%-85%) by colposcopic and histological verification, respectively. Regression rates were 100% and 60%. There were two related non-serious adverse events.Conclusions. Cure and regression rates by colposcopic verification are like those reported for cryotherapy delivered by doctors. The sample size (CIN2/3) hinders comparisons by type of verification. Our findings support the implementation of screen-and-treat algorithms by nurses among populations with limited access to health services., Introducción. El cáncer de cuello uterino es un problema de salud pública relevante en países de ingresos medios y bajos. El seguimiento de mujeres con tamización positiva y el acceso a tratamiento para neoplasia intraepitelial cervical (NIC) son retos mayores en estos países.Objetivo. Evaluar la efectividad de la crioterapia suministrada por enfermeras en casos de neoplasia intraepitelial de cérvix.Materiales y métodos. Se hizo la inspección visual directa con ácido acético y solución yodada (VIA-VILI), y se practicó colposcopia con biopsia, a mujeres entre los 25 y los 59 años, residentes en zonas de bajos ingresos de Bogotá. Profesionales de enfermería entrenados ofrecieron tratamiento inmediato con crioterapia a mujeres positivas en la inspección visual. Se les practicó colposcopia con biopsia antes del tratamiento y en un control a los 12 meses. Se evaluó la efectividad mediante tasas de curación (resultado: sin lesión) y regresión de NIC2/3 (resultado: ≤NIC1), por verificación colposcópica e histológica.Resultados. Se tamizaron 4.957 mujeres. En total, 499 fueron positivas y 472 aceptaron el tratamiento inmediato. Recibieron crioterapia por enfermería 365 mujeres (11 NIC2/3). La tasa de curación fue del 72 % (IC95%: 39-94 %) por verificación colposcópica, y del 40 % (IC95%: 22-85 %) por histología. Las tasas de regresión fueron del 100 y el 60 %, respectivamente. Se reportaron dos eventos adversos no graves relacionados.Conclusiones. Las tasas de curación y regresión por verificación colposcópica son similares a las reportadas con crioterapia administrada por médicos. El tamaño de la muestra con NIC2/3 dificulta la comparación por tipo de verificación. Los hallazgos apoyan la implementación de estrategias de “ver y tratar” por parte de enfermería en poblaciones con acceso limitado a servicios de salud.

74 p. -- Bibliogr.: p. 27-30, Introducción: La Mucositis Oral (MO) representa una reacción inflamatoria de la mucosa de la cavidad oral, que constituye uno de los efectos adversos más frecuentes y debilitantes causado por la toxicidad de los tratamientos antineoplásicos. Sus consecuencias físicas, psicológicas, sociales y económicas suponen un impacto potencial en la calidad de vida y supervivencia de los pacientes oncológicos, pudiendo llegar a precisar una reducción de la dosis o interrupción del tratamiento. Ante esta emergente situación, surge la necesidad de emplear estrategias preventivas y/o terapéuticas que sean eficaces. Objetivo: Identificar la efectividad de distintas intervenciones no farmacológicas (Crioterapia Oral, Miel y Aloe Vera) para prevenir y/o reducir la severidad de la MO en pacientes oncológicos, sometidos a Radioterapia y/o Quimioterapia. Metodología: Para efectuar la investigación, se llevó a cabo una Revisión Crítica de la Literatura, siguiendo un método exhaustivo y riguroso de búsqueda en diversas Bases de Datos y otras fuentes de información, a partir de la elaboración de ecuaciones con las palabras clave obtenidas. Tras un proceso de selección sistemático, se incluyeron 18 artículos en la revisión, cuyos resultados se categorizaron en las dimensiones de Crioterapia Oral y Productos Naturales. Resultados: Se objetivó una disminución de la incidencia y severidad de la MO en aquellas personas que recibieron Crioterapia Oral, con diferencias significativas entre los grupos experimental y control en la mayoría de los artículos revisados. La Miel y Aloe Vera demostraron su efectividad en la reducción de la intensidad de este efecto adverso, aunque no lograron prevenir su aparición. Conclusiones: Basándose en la evidencia disponible, las medidas no farmacológicas analizadas pueden tener un beneficio clínico contra la MO inducida por la Radioterapia y/o Quimioterapia. No obstante, la existencia de limitaciones en algunos estudios justifica la necesidad de continuar con la

Post-exercise cooling is a popular recovery strategy utilized by athletes, and of interest to many research groups. Significant body of research have examined the effects of post-exercise cooling on outcomes such as physical performance, regulation of inflammatory biomarkers, and psychophysical indices related to perceived fatigue, recovery and wellbeing. ...

BackgroundChemotherapy-induced peripheral neuropathy (CIPN) is a serious side effect that is highly prevalent among cancer patients undergoing chemotherapy. There is a growing use of cryotherapy (CryTx) and compression therapy (ComTx) to prevent CIPN at cancer centers worldwide. In this study, we examined the awareness and recommendation of these modalities and evaluated factors associated with awareness. In addition, we investigated the type of technology utilized, barriers to implementation, and perceived adverse events of CryTx and ComTx.MethodsActive members of the Multinational Association of Supportive Care of Cancer (MASCC) were invited to complete an electronic survey that was sent via SurveyMonkey between September and October 2021. The survey assessed participants' awareness, recommendation, usage, barriers to utilization, and perceived adverse events of CryTx and ComTx. Descriptive statistics and multiple logistic regression were utilized to analyze findings.ResultsOut of 184 participants, 70.1% were physicians, 73.4% had over 10 years of practice, and 49.5% were practicing in an outpatient setting. While more than half (63.3%) of participants indicated awareness of CryTx for taxane-induced peripheral neuropathy, less than a quarter (22.8%) indicated recommendation in their practice setting. Factors associated with higher awareness of CryTx for patients receiving taxanes include living in Europe (OR = 2.69, 95% CI [1.28-5.64], p = 0.009), not practicing in an inpatient setting (OR = 3.15, 95% CI [1.45-6.85], p = 0.004), and self-identifying as non-physician (OR = 2.40, 95% CI [1.03-4.37], p = 0.041). Commercial cooling (31.5%) and compression (16.8%) gloves and socks were the most used modalities for CryTx and ComTx, respectively. The most identified barriers to CryTx and ComTx utilization include insufficient evidence (53.5%), logistics (34.8%), and patient discomfort (23.4%). Redness/irritation of skin (27.7%) and numbness/tingling (24.5%) accounte

Post-exercise cooling is a popular recovery strategy utilized by athletes, and of interest to many research groups. Significant body of research have examined the effects of post-exercise cooling on outcomes such as physical performance, regulation of inflammatory biomarkers, and psychophysical indices related to perceived fatigue, recovery and wellbeing. ...

We report a case of a nine-year-old boy with clinical evidence of foreign body (FB) aspiration with 3 months of delay in diagnosis. The bronchoscopy found soft tissue FB with surrounding inflamed granulation tissue at the entrance to the lateral segmental bronchus. Repeated attempts to remove the FB with flexible forceps were unsuccessful due to friable FB and granulation tissue. Ablation of the granulation tissue using nitrous oxide cryotherapy was then successfully performed and the distal and organic FB was extracted. Early diagnosis is important for minimizing granulation tissue development which complicates FB removal. Cryotherapy with a flexible bronchoscope is an option if organic FB cannot be removed using conventional bronchoscopic instrumentation.

Introduction: Pain control is an essential component of musculoskeletal injury treatment in the emergency department (ED). We evaluated the most effective type of cryotherapy for analgesia of acute musculoskeletal injury and the impact on opioid utilization.Methods: This was a prospective, randomized, single-blind controlled trial of adult ED patients who presented with acute musculoskeletal pain. Patients were randomized to either intensive targeted cryotherapy (crushed wetted ice in a plastic bag) or agitated chemical cold pack applied to the injury site for 20 minutes. All other diagnostic and therapeutic orders were at the discretion of the treating physician. Visual analog pain scores were measured at the time of cryotherapy application, at 20 minutes (time of cryotherapy removal), and at 60 minutes (40 minutes after removal).Results: We enrolled 38 patients, 17 randomized to intensive targeted cryotherapy and 21 to chemical cold packs, with well-matched demographics. The intensive targeted cryotherapy group achieved significantly greater pain relief at 20 minutes (2.1 [95% confidence interval (CI), 1.3 – 2.9] vs 0.9 [95% CI, 0.3 – 1.5], P < 0.05) and at 60 minutes (2.7 [95% CI, 1.6 – 3.7] vs 1.2 [95% CI, 0.6 – 1.7], P < 0.05), number need to trial (NNT) = 3.2. Opioid administration in the ED was significantly lower in the intensive targeted cryotherapy group (1 [6%] vs 7 [33%], P < 0.05), NNT = 3.6. Those who received a discharge opiate prescription had significantly higher 60-minute pain scores (7.3 ± 2.2 vs 4.1 ± 2.7, P < 0.05).Conclusion: Intensive targeted cryotherapy provided more effective analgesia than chemical cold packs for acute musculoskeletal injuries in the ED and may contribute to lower opioid usage.

[Resumen] Objetivo El principal objetivo es recopilar la actualidad científica de los principales tratamientos para la verruga plantar que más se utilizan en la práctica diaria en la clínica o ámbito clínico podológico. Es por eso, que se tiene en cuenta tratamientos como el ácido salicílico, crioterapia, ácido nítrico, cantaridina y el láser. Metodología Se ha realizado una búsqueda en las diferentes bases de datos científicas como Scopus y Cinahl, y a mayores en el caso del ácido nítrico en Pubmed y Web of Science. Se han incluido artículos entre 2011 y 2021 que cumplen los criterios de inclusión. Conclusión El tratamiento que ofrece una mejor solución es el ácido salicílico como tratamiento de 1ª línea para el aclaramiento de las verrugas plantares. Cuando este no resulte efectivo, se escoge la cantaridina, como 2ª línea de tratamiento por ser la que mejores porcentajes de curación tiene en verrugas plantares., [Abstract] Objective The main objective is to collect the scientific news of the main plantar wart treatments that are most used in daily practice in the podiatric clinic or clinical setting. That is why treatments such as salicylic acid, cryotherapy, nitric acid, cantharidin and laser are taken into account. Methodology A search has been carried out in the different scientific databases such as Scopus and Cinahl, and in the case of nitric acid in Pubmed and Web of Science. Articles between 2011 and 2021 that meet the inclusion criteria have been included. Conclution The treatment that offers a better solution is salicylic acid as a 1st line treatment for the clearance of plantar warts. When this is not effective, cantharidin is chosen as the 2nd line of treatment because it is the one with the best healing percentages in plantar warts.

This is a comment on a network meta-analysis that evaluated the ranking of treatments for actinic keratosis outside the head and neck. The results of a limited number of heterogeneous studies contrast with the results of studies in the head and neck area. The extent to which these results can be generalized to larger treatment fields or areas with extensive field cancerization is uncertain.

This survey sought to establish current use, knowledge and perceptions of cold-water immersion (CWI) when used for recovery. 111 athletes, coaches and support practitioners completed the anonymous online survey, answering questions about their current CWI protocols, perceptions of benefits associated with CWI and knowledge of controlling mechanisms. Respondents were largely involved in elite sport at international, national and club level, with many having used CWI previously (86%) and finding its use beneficial for recovery (78%). Protocols differed, with the duration of immersion one aspect that failed to align with recommendations in the scientific literature. Whilst many respondents were aware of benefits associated with CWI, there remains some confusion. There also seems to be a gap in mechanistic knowledge, where respondents are aware of benefits associated with CWI, but failed to identify the underlying mechanisms. This identifies the need for an improved method of knowledge transfer between scientific and applied practice communities. Moreover, data herein emphasises the important role of the ‘support practitioner’ as respondents in this role tended to favour CWI protocols more aligned to recommendations within the literature. With a significant number of respondents claiming they were made aware of CWI for recovery through a colleague (43%), the importance of knowledge transfer and context being appropriately applied to data is as important as ever. With the firm belief that CWI is useful for recovery in sport, the focus should now be on investigating the psychophysiological interaction and correct use of this methodology.

Bakgrund Vården rör sig mot en mer patientcentrerad syn. Detta reflekteras i den fysioterapeutiska behandlingen där man kan se holistiska modaliteter göra ett inträde. En metod utanför skolmedicinens ramar som samlat uppmärksamhet det senaste decenniet är Wim Hof-Metoden. Den bygger på köldterapi, andningsövning och meditation. För var av dessa delar finns stöd, och lovande forskning har utförts på metoden i sig. Dock så är stödet fortfarande begränsat. Syfte Undersöka om utövandet av Wim Hof-metoden under tre veckor ger effekter på livskvalitet och självskattad hälsa. Metod Deltagare rekryterades via mail och annonser på social media. 8 individer utav 14 intresserade (57%) avlade medgivande och påbörjade intervention. Under tre veckor utförde de dagligen Wim Hof-Metoden. En mätning av livskvalitet med formuläret RAND-36 gjordes vid baseline och efter intervention. Så även med en generell hälsoskattning ur formuläret EQ-5L. Resultat Av 8 deltagare genomförde 5 (62,5%) studien. Således skedde ett bortfall på 3 individer (37,5 %). Efter intervention kunde man se parametriska tendenser till en ökad livskvalitet enligt RAND-36, där sammanlagt medelvärde för domänerna vitalitet, psykiskt välbefinnande och allmän hälsa ökade från 61,6 till 71,0 poäng. För generell hälsa enligt barometern från EQ-5L ökade medelvärdet från 75,4 till 85,6 enheter. Diskussion Resultatet indikerar tendenser till ökad livskvalitet och generell hälsa. Dock var antalet deltagare för lågt för statistisk analys, och gruppens förväntningar höga - vilket sänker datans tillförlitlighet. Forskning av större omfattning och med högre kvalitet behövs för att dra slutsatser kring metodens verkan.

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

Introduction: Pain control is an essential component of musculoskeletal injury treatment in the emergency department (ED). We evaluated the most effective type of cryotherapy for analgesia of acute musculoskeletal injury and the impact on opioid utilization.Methods: This was a prospective, randomized, single-blind controlled trial of adult ED patients who presented with acute musculoskeletal pain. Patients were randomized to either intensive targeted cryotherapy (crushed wetted ice in a plastic bag) or agitated chemical cold pack applied to the injury site for 20 minutes. All other diagnostic and therapeutic orders were at the discretion of the treating physician. Visual analog pain scores were measured at the time of cryotherapy application, at 20 minutes (time of cryotherapy removal), and at 60 minutes (40 minutes after removal).Results: We enrolled 38 patients, 17 randomized to intensive targeted cryotherapy and 21 to chemical cold packs, with well-matched demographics. The intensive targeted cryotherapy group achieved significantly greater pain relief at 20 minutes (2.1 [95% confidence interval (CI), 1.3 – 2.9] vs 0.9 [95% CI, 0.3 – 1.5], P < 0.05) and at 60 minutes (2.7 [95% CI, 1.6 – 3.7] vs 1.2 [95% CI, 0.6 – 1.7], P < 0.05), number need to trial (NNT) = 3.2. Opioid administration in the ED was significantly lower in the intensive targeted cryotherapy group (1 [6%] vs 7 [33%], P < 0.05), NNT = 3.6. Those who received a discharge opiate prescription had significantly higher 60-minute pain scores (7.3 ± 2.2 vs 4.1 ± 2.7, P < 0.05).Conclusion: Intensive targeted cryotherapy provided more effective analgesia than chemical cold packs for acute musculoskeletal injuries in the ED and may contribute to lower opioid usage.

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

Purpose: To update the 2015 clinical practice guideline for the prevention of oral mucositis in pediatric cancer or hematopoietic stem cell transplant (HSCT) patients. Methods: We performed seven systematic reviews of mucositis prevention. Three reviews included randomized controlled trials (RCTs) conducted in pediatric and adult patients evaluating cryotherapy, keratinocyte growth factor (KGF) or photobiomodulation therapy with a focus on efficacy. Three reviews included studies of any design conducted in pediatric patients evaluating these same interventions with a focus on adverse events and feasibility. One review included all RCTs of any intervention for mucositis prevention in pediatric patients. Primary outcome was severe oral mucositis.

Purpose: To update the 2015 clinical practice guideline for the prevention of oral mucositis in pediatric cancer or hematopoietic stem cell transplant (HSCT) patients. Methods: We performed seven systematic reviews of mucositis prevention. Three reviews included randomized controlled trials (RCTs) conducted in pediatric and adult patients evaluating cryotherapy, keratinocyte growth factor (KGF) or photobiomodulation therapy with a focus on efficacy. Three reviews included studies of any design conducted in pediatric patients evaluating these same interventions with a focus on adverse events and feasibility. One review included all RCTs of any intervention for mucositis prevention in pediatric patients. Primary outcome was severe oral mucositis.

ContextManagement of locally recurrent prostate cancer after definitive radiotherapy remains controversial due to the perceived high rates of severe genitourinary (GU) and gastrointestinal (GI) toxicity associated with any local salvage modality.ObjectiveTo quantitatively compare the efficacy and toxicity of salvage radical prostatectomy (RP), high-intensity focused ultrasound (HIFU), cryotherapy, stereotactic body radiotherapy (SBRT), low-dose-rate (LDR) brachytherapy, and high-dose-rate (HDR) brachytherapy.Evidence acquisitionWe performed a systematic review of PubMed, EMBASE, and MEDLINE. Two- and 5-yr recurrence-free survival (RFS) rates and crude incidences of severe GU and GI toxicity were extracted as endpoints of interest. Random-effect meta-analyses were conducted to characterize summary effect sizes and quantify heterogeneity. Estimates for each modality were then compared with RP after adjusting for individual study-level covariates using mixed-effect regression models, while allowing for differences in between-study variance across treatment modalities.Evidence synthesisA total of 150 studies were included for analysis. There was significant heterogeneity between studies within each modality, and covariates differed between modalities, necessitating adjustment. Adjusted 5-yr RFS ranged from 50% after cryotherapy to 60% after HDR brachytherapy and SBRT, with no significant differences between any modality and RP. Severe GU toxicity was significantly lower with all three forms of radiotherapeutic salvage than with RP (adjusted rates of 20% after RP vs 5.6%, 9.6%, and 9.1% after SBRT, HDR brachytherapy, and LDR brachytherapy, respectively; p ≤ 0.001 for all). Severe GI toxicity was significantly lower with HDR salvage than with RP (adjusted rates 1.8% vs 0.0%, p < 0.01), with no other differences identified.ConclusionsLarge differences in 5-yr outcomes were not uncovered when comparing all salvage treatment modalities against RP. Reirradiation with SBRT

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

Objective: To analyze the efficacy of treatments for the prevention of oral mucositis in cancer patients. Methodology: A systematic review was carried out from various databases (Medline, Web of Science, EBSCOHost), including articles ran ging from 2015 to 2020. Results: within the 26 articles included in the present review, those published in 2016 and 2019 predominated and were mostly obtained through Medline. A level of evidence 1b stands out corresponding to a grade of recommendation A. Conclusions: Oral cryotherapy and low-level laser therapy achieve a lower incidence of oral mucositis and a decrease in the degree of severity. Both therapies promote pain relief in oncology patients with oral mucositis., Objetivo: Analizar la eficacia de los tratamientos para la prevención de la mucositis oral en pacientes oncológicos. Metodología: Se llevó a cabo un a revisión sistemática a partir de diversas bases de datos (Medline, Web of Science, EBSCOHost), incluyendo artículos compren didos desde 2015 hasta 2020. Resultados: Dentro de los 26 artículos incluidos en el presente trabajo predominaron aquellos public ados en 2016 y 2019 , en su mayoría a través de Medline. Destaca un nivel de evidencia 1b, correspondiendo con un grado de recomendación A. Conclusiones: La crioterapia oral y la terapia con láser de baja intensidad logran menor incidencia de mucositis ora l y disminución en el grado de gravedad. Ambas terapias promueven alivio del dolor en los pacientes oncológicos que presentan mucositis oral.

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

Purpose: To update the 2015 clinical practice guideline for the prevention of oral mucositis in pediatric cancer or hematopoietic stem cell transplant (HSCT) patients. Methods: We performed seven systematic reviews of mucositis prevention. Three reviews included randomized controlled trials (RCTs) conducted in pediatric and adult patients evaluating cryotherapy, keratinocyte growth factor (KGF) or photobiomodulation therapy with a focus on efficacy. Three reviews included studies of any design conducted in pediatric patients evaluating these same interventions with a focus on adverse events and feasibility. One review included all RCTs of any intervention for mucositis prevention in pediatric patients. Primary outcome was severe oral mucositis.

Bakgrund Vården rör sig mot en mer patientcentrerad syn. Detta reflekteras i den fysioterapeutiska behandlingen där man kan se holistiska modaliteter göra ett inträde. En metod utanför skolmedicinens ramar som samlat uppmärksamhet det senaste decenniet är Wim Hof-Metoden. Den bygger på köldterapi, andningsövning och meditation. För var av dessa delar finns stöd, och lovande forskning har utförts på metoden i sig. Dock så är stödet fortfarande begränsat. Syfte Undersöka om utövandet av Wim Hof-metoden under tre veckor ger effekter på livskvalitet och självskattad hälsa. Metod Deltagare rekryterades via mail och annonser på social media. 8 individer utav 14 intresserade (57%) avlade medgivande och påbörjade intervention. Under tre veckor utförde de dagligen Wim Hof-Metoden. En mätning av livskvalitet med formuläret RAND-36 gjordes vid baseline och efter intervention. Så även med en generell hälsoskattning ur formuläret EQ-5L. Resultat Av 8 deltagare genomförde 5 (62,5%) studien. Således skedde ett bortfall på 3 individer (37,5 %). Efter intervention kunde man se parametriska tendenser till en ökad livskvalitet enligt RAND-36, där sammanlagt medelvärde för domänerna vitalitet, psykiskt välbefinnande och allmän hälsa ökade från 61,6 till 71,0 poäng. För generell hälsa enligt barometern från EQ-5L ökade medelvärdet från 75,4 till 85,6 enheter. Diskussion Resultatet indikerar tendenser till ökad livskvalitet och generell hälsa. Dock var antalet deltagare för lågt för statistisk analys, och gruppens förväntningar höga - vilket sänker datans tillförlitlighet. Forskning av större omfattning och med högre kvalitet behövs för att dra slutsatser kring metodens verkan.

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

Rheumatoid arthritis is a very degenerative disease, which if not treated in time can cause a very serious disability to those who suffer from it, since this disease causes pain and inflammation in the diarthrodial joints that affects approximately 1% of the population. Among the many treatments that can be used, cryotherapy is a technique that can be used, since it is used in other muscle diseases with good results. The research methodology is a bibliographic review, supported by electronic media as the primary source for obtaining information, the works found gave fundamental contributions to the achievement of this work. The fundamental conclusion is that cryotherapy or chrysotherapy shows that it mitigates pain and inflammation in its different therapeutic modalities (cryomassage, immersion in ice water, ice pack), since it produces a delay of the sodium channels, which retard the currents of sodium responsible for the depolarization of nerve and muscle fibers, which would explain the increase in pain threshold and the potential hypoalgesic effect attributed to cryotherapy, La artritis reumatoide es una enfermedad muy degenerativa, que si no es tratada a tiempo puede producir una discapacidad muy grave a quien la padece, ya que esta enfermedad, produce dolor e inflamación en las articulaciones diartrodiales que afecta aproximadamente al 1% de la población. Entre los múltiples tratamientos que se pueden utilizar, la crioterapia es una técnica que puede ser empleada, ya que es utilizada en otras enfermedades musculares con buenos resultados. La metodología de la investigación es una revisión bibliográfica, apoyada en medios electrónicos como fuente primaria de obtención de la información, los trabajos encontrados dieron aportes fundamentales para la consecución de este trabajo. La conclusión fundamental es que la crioterapia o crisoterapia demuestra que mitiga el dolor y las inflamaciones en sus diferentes modalidades terapéuticas (criomasaje, inmersión en agua helada, paquete de hielo), ya que produce un retraso de los canales de sodio, que retardan las corrientes de sodio responsables de la despolarización de las fibras nerviosas, musculares, que explicarían el aumento del umbral del dolor y el potencial efecto hipoalgésico atribuido a la crioterapia.

This is a comment on a network meta-analysis that evaluated the ranking of treatments for actinic keratosis outside the head and neck. The results of a limited number of heterogeneous studies contrast with the results of studies in the head and neck area. The extent to which these results can be generalized to larger treatment fields or areas with extensive field cancerization is uncertain.

This survey sought to establish current use, knowledge and perceptions of cold-water immersion (CWI) when used for recovery. 111 athletes, coaches and support practitioners completed the anonymous online survey, answering questions about their current CWI protocols, perceptions of benefits associated with CWI and knowledge of controlling mechanisms. Respondents were largely involved in elite sport at international, national and club level, with many having used CWI previously (86%) and finding its use beneficial for recovery (78%). Protocols differed, with the duration of immersion one aspect that failed to align with recommendations in the scientific literature. Whilst many respondents were aware of benefits associated with CWI, there remains some confusion. There also seems to be a gap in mechanistic knowledge, where respondents are aware of benefits associated with CWI, but failed to identify the underlying mechanisms. This identifies the need for an improved method of knowledge transfer between scientific and applied practice communities. Moreover, data herein emphasises the important role of the ‘support practitioner’ as respondents in this role tended to favour CWI protocols more aligned to recommendations within the literature. With a significant number of respondents claiming they were made aware of CWI for recovery through a colleague (43%), the importance of knowledge transfer and context being appropriately applied to data is as important as ever. With the firm belief that CWI is useful for recovery in sport, the focus should now be on investigating the psychophysiological interaction and correct use of this methodology.

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Background: Separately, cryotherapy and brachytherapy have shown promising results when adjuvating the excision of squamous cell carcinoma of the conjunctiva (SCCC). The aim of this paper is to assess the combined effect in terms of complications and recurrence rate. Summary: We describe 2 patients suffering from SCCC, and we review the current literature on adjuvant cryotherapy and brachytherapy. Both patients, one of whom suffered from recurrent SCCC, underwent surgical excision followed by combined cryotherapy and brachytherapy. Cryotherapy was performed using a retinal cryoprobe, and 2 rounds each of 5 s with N2O as a cryogen were applied. Brachytherapy was performed using a ruthenium-106 plaque, delivering a dosage of 100 Gy at 2-mm depth. Key Messages: By reviewing the current literature and describing 2 case reports, this paper illustrates the use of combined cryotherapy and brachytherapy after surgical excision of SCCC. The current literature presents promising results of each treatment, and the 2 cases showed promising results by combining the 2 adjuvant therapies showing no signs of recurrence or complications during a follow-up period of 26 and 38 months.

[Resumen] Objetivo El principal objetivo es recopilar la actualidad científica de los principales tratamientos para la verruga plantar que más se utilizan en la práctica diaria en la clínica o ámbito clínico podológico. Es por eso, que se tiene en cuenta tratamientos como el ácido salicílico, crioterapia, ácido nítrico, cantaridina y el láser. Metodología Se ha realizado una búsqueda en las diferentes bases de datos científicas como Scopus y Cinahl, y a mayores en el caso del ácido nítrico en Pubmed y Web of Science. Se han incluido artículos entre 2011 y 2021 que cumplen los criterios de inclusión. Conclusión El tratamiento que ofrece una mejor solución es el ácido salicílico como tratamiento de 1ª línea para el aclaramiento de las verrugas plantares. Cuando este no resulte efectivo, se escoge la cantaridina, como 2ª línea de tratamiento por ser la que mejores porcentajes de curación tiene en verrugas plantares., [Abstract] Objective The main objective is to collect the scientific news of the main plantar wart treatments that are most used in daily practice in the podiatric clinic or clinical setting. That is why treatments such as salicylic acid, cryotherapy, nitric acid, cantharidin and laser are taken into account. Methodology A search has been carried out in the different scientific databases such as Scopus and Cinahl, and in the case of nitric acid in Pubmed and Web of Science. Articles between 2011 and 2021 that meet the inclusion criteria have been included. Conclution The treatment that offers a better solution is salicylic acid as a 1st line treatment for the clearance of plantar warts. When this is not effective, cantharidin is chosen as the 2nd line of treatment because it is the one with the best healing percentages in plantar warts.

Purpose: To update the 2015 clinical practice guideline for the prevention of oral mucositis in pediatric cancer or hematopoietic stem cell transplant (HSCT) patients. Methods: We performed seven systematic reviews of mucositis prevention. Three reviews included randomized controlled trials (RCTs) conducted in pediatric and adult patients evaluating cryotherapy, keratinocyte growth factor (KGF) or photobiomodulation therapy with a focus on efficacy. Three reviews included studies of any design conducted in pediatric patients evaluating these same interventions with a focus on adverse events and feasibility. One review included all RCTs of any intervention for mucositis prevention in pediatric patients. Primary outcome was severe oral mucositis.

Purpose: To update the 2015 clinical practice guideline for the prevention of oral mucositis in pediatric cancer or hematopoietic stem cell transplant (HSCT) patients. Methods: We performed seven systematic reviews of mucositis prevention. Three reviews included randomized controlled trials (RCTs) conducted in pediatric and adult patients evaluating cryotherapy, keratinocyte growth factor (KGF) or photobiomodulation therapy with a focus on efficacy. Three reviews included studies of any design conducted in pediatric patients evaluating these same interventions with a focus on adverse events and feasibility. One review included all RCTs of any intervention for mucositis prevention in pediatric patients. Primary outcome was severe oral mucositis.

[ES] En el presente proyecto se realiza el estudio y diseño de un gorro hipotérmico para prevenir la alopecia inducida por la quimioterapia. Se trata de un producto que incorporará materiales de cambio de fase (PCMs) en su estructura textil para enfriar el cuero cabelludo hasta los 18 °C. Este artículo textil facilitará al acceso a la crioterapia capilar a aquellos usuarios que no puedan costearse las costosas terapias de crioterapia existentes en el mercado. Al mismo tiempo se diseñará un pañuelo o turbante oncológico para cubrir el gorro hipotérmico y contribuir a una mejor imagen del paciente durante su uso. Este producto se ha diseñado para que pueda ser reversible con distintas características en cada cara del tejido. De esta forma podrá ser utilizado por los usuarios del gorro hipotérmico, sobreponiéndose sobre éste para dotar de un mejor aspecto al usuario. También podrá ser de gran utilidad para los pacientes que la crioterapia no les ha resultado efectiva o que han decidido no someterse a esta terapia, propiciando de esta forma la caída del cabello. El turbante podrá proteger el sensible cuero cabelludo y ofrecerle diversos beneficios., [EN] In the present project, the study and design of a hypothermic cap is carried out to prevent chemotherapy-induced alopecia. It is a product that will incorporate phase change materials (PCMs) in its textile structure to cool the scalp to 18 ° C. This textile article will facilitate access to hair cryotherapy for those users who cannot afford the expensive cryotherapy therapies available on the market. At the same time, an oncological scarf or turban will be designed to cover the hypothermic cap and contribute to a better image of the patient during its use. This product has been designed to be reversible with different characteristics in each face of the fabric. In this way, it can be used by users of the hypothermic cap, overlapping it to give the user a better appearance. It can also be very useful for patients who have not been effective cryotherapy or who have decided not to undergo this therapy, thus promoting hair loss. The turban will be able to protect the sensitive scalp and offer various benefits.

[ES] En el presente proyecto se realiza el estudio y diseño de un gorro hipotérmico para prevenir la alopecia inducida por la quimioterapia. Se trata de un producto que incorporará materiales de cambio de fase (PCMs) en su estructura textil para enfriar el cuero cabelludo hasta los 18 °C. Este artículo textil facilitará al acceso a la crioterapia capilar a aquellos usuarios que no puedan costearse las costosas terapias de crioterapia existentes en el mercado. Al mismo tiempo se diseñará un pañuelo o turbante oncológico para cubrir el gorro hipotérmico y contribuir a una mejor imagen del paciente durante su uso. Este producto se ha diseñado para que pueda ser reversible con distintas características en cada cara del tejido. De esta forma podrá ser utilizado por los usuarios del gorro hipotérmico, sobreponiéndose sobre éste para dotar de un mejor aspecto al usuario. También podrá ser de gran utilidad para los pacientes que la crioterapia no les ha resultado efectiva o que han decidido no someterse a esta terapia, propiciando de esta forma la caída del cabello. El turbante podrá proteger el sensible cuero cabelludo y ofrecerle diversos beneficios., [EN] In the present project, the study and design of a hypothermic cap is carried out to prevent chemotherapy-induced alopecia. It is a product that will incorporate phase change materials (PCMs) in its textile structure to cool the scalp to 18 ° C. This textile article will facilitate access to hair cryotherapy for those users who cannot afford the expensive cryotherapy therapies available on the market. At the same time, an oncological scarf or turban will be designed to cover the hypothermic cap and contribute to a better image of the patient during its use. This product has been designed to be reversible with different characteristics in each face of the fabric. In this way, it can be used by users of the hypothermic cap, overlapping it to give the user a better appearance. It can also be very useful for patients who have not been effective cryotherapy or who have decided not to undergo this therapy, thus promoting hair loss. The turban will be able to protect the sensitive scalp and offer various benefits.