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Mahmoud Farghaly,1 Abdallah Kamal,1,2 Maged El-Setouhy,3,4 Jon Mark Hirshon,5,6 Mohamed El-Shinawi1,7 1Department of General Surgery, Ain Shams University, Cairo, Egypt; 2Department of Radiology, Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA; 3Department of Community, Environmental and Occupational Medicine, Ain Shams University, Cairo, Egypt; 4Department of Family and Community Medicine, Jazan University, Jazan, Saudi Arabia; 5Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD, USA; 6Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA; 7Department of Medical Education, Galala University, Cairo, EgyptCorrespondence: Mahmoud FarghalyDepartment of General Surgery, Ain Shams University, Cairo, EgyptTel +20 1001775378Email Mahmoudfarghali@med.asu.edu.egStudy Design: Retrograde cross-sectional study.Objective: To assess patient satisfaction and outcomes in polytraumatized patients in EL-Demerdash hospital.Background: This is the first study that assessed patient satisfaction with a tertiary hospital in Egypt. Ain Shams University Surgery Hospital, which is one of the largest hospitals in Egypt and serves millions of patients each year, was the site of the study.Methods: A version of the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey was used to query 361 patients from November 2015 until July 2018 Survey questions were divided into the following categories: communication with doctors, responsiveness of hospital staff, cleanliness of the hospital environment, quietness of the hospital environment, pain management, communication about medicines, discharge information, overall rating of the hospital, and willingness to recommend the hospital.Results: A total of 361 patients were interviewed. The results showed both positive and negative levels of satisfaction. The positive results included no delay in admission, friendly st

This thesis describes the development of several analytical methods, based on electrochemical techniques, for the determination of various drug substances in formulations, biological fluids and environmental samples. The work included a study of the voltammetric behaviour of both sumatriptan succinate and salbutamol sulphate at a glassy carbon electrode. Based on these studies, simple, rapid and sensitive voltammetric methods were developed for the determination of these drugs in tablet dosage forms without any interferences from the excipients. Using differential pulse voltammetry, the dissolution profile of salbutamol tablets was also investigated. The principal criteria for designing electrochemical flow detectors, and the great advantages of carbon fibre electrodes, have been utilized in the development of a versatile electrochemical detector for HPLC that is based on a carbon fibre (14 pm diameter) placed in a polyethylene tube connected directly to the end of the chromatographic column. The analysis of salbutamol in human plasma was then developed based on extracting the drug from the plasma into an organic solvent and separation of the drug on a reversed-phase Cjg column, followed by detection using the carbon fibre flow electrode. Several advantages of the carbon-fiber flow electrodes over conventional electrodes have also been demonstrated. The cell was then used for monitoring of terbutaline concentrations in human plasma in the range of 1-35 ngml'l using columnswitching LC. The method involved direct injection of the plasma sample into a Ci 8 extraction column for sample clean-up. This method was also applied for the simultaneous determination of both salbutamol and terbutaline at overdose levels in human plasma. A method was then developed to determine the suspected carcinogen gentian violet in human urine and in poultry feed. Liquid chromatography with electrochemical detection was also applied in environmental studies for the analysis of malachite gree

This thesis describes the development of several analytical methods, based on electrochemical techniques, for the determination of various drug substances in formulations, biological fluids and environmental samples. The work included a study of the voltammetric behaviour of both sumatriptan succinate and salbutamol sulphate at a glassy carbon electrode. Based on these studies, simple, rapid and sensitive voltammetric methods were developed for the determination of these drugs in tablet dosage forms without any interferences from the excipients. Using differential pulse voltammetry, the dissolution profile of salbutamol tablets was also investigated. The principal criteria for designing electrochemical flow detectors, and the great advantages of carbon fibre electrodes, have been utilized in the development of a versatile electrochemical detector for HPLC that is based on a carbon fibre (14 pm diameter) placed in a polyethylene tube connected directly to the end of the chromatographic column. The analysis of salbutamol in human plasma was then developed based on extracting the drug from the plasma into an organic solvent and separation of the drug on a reversed-phase Cjg column, followed by detection using the carbon fibre flow electrode. Several advantages of the carbon-fiber flow electrodes over conventional electrodes have also been demonstrated. The cell was then used for monitoring of terbutaline concentrations in human plasma in the range of 1-35 ngml'l using columnswitching LC. The method involved direct injection of the plasma sample into a Ci 8 extraction column for sample clean-up. This method was also applied for the simultaneous determination of both salbutamol and terbutaline at overdose levels in human plasma. A method was then developed to determine the suspected carcinogen gentian violet in human urine and in poultry feed. Liquid chromatography with electrochemical detection was also applied in environmental studies for the analysis of malachite gree

This thesis describes the development of several analytical methods, based on electrochemical techniques, for the determination of various drug substances in formulations, biological fluids and environmental samples. The work included a study of the voltammetric behaviour of both sumatriptan succinate and salbutamol sulphate at a glassy carbon electrode. Based on these studies, simple, rapid and sensitive voltammetric methods were developed for the determination of these drugs in tablet dosage forms without any interferences from the excipients. Using differential pulse voltammetry, the dissolution profile of salbutamol tablets was also investigated. The principal criteria for designing electrochemical flow detectors, and the great advantages of carbon fibre electrodes, have been utilized in the development of a versatile electrochemical detector for HPLC that is based on a carbon fibre (14 pm diameter) placed in a polyethylene tube connected directly to the end of the chromatographic column. The analysis of salbutamol in human plasma was then developed based on extracting the drug from the plasma into an organic solvent and separation of the drug on a reversed-phase Cjg column, followed by detection using the carbon fibre flow electrode. Several advantages of the carbon-fiber flow electrodes over conventional electrodes have also been demonstrated. The cell was then used for monitoring of terbutaline concentrations in human plasma in the range of 1-35 ngml'l using columnswitching LC. The method involved direct injection of the plasma sample into a Ci 8 extraction column for sample clean-up. This method was also applied for the simultaneous determination of both salbutamol and terbutaline at overdose levels in human plasma. A method was then developed to determine the suspected carcinogen gentian violet in human urine and in poultry feed. Liquid chromatography with electrochemical detection was also applied in environmental studies for the analysis of malachite gree