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1. 2021 Asia Pacific Heart Rhythm Society (APHRS) practice guidance on atrial fibrillation screening

Author

Chan, N-Y, Orchard, J, Agbayani, M-J, Boddington, D, Chao, T-F, Johar, S, John, B, Joung, B, Krishinan, S, Krittayaphong, R, Kurokawa, S, Lau, C-P, Lim, TW, Pham, TL, Vien, HL, Naik, A, Okumura, Y, Sasano, T, Yan, B, Raharjo, SB, Hanafy, DA, Yuniadi, Y, Nwe, N, Awan, ZA, Huang, H, Freedman, B, Chan, N-Y, Orchard, J, Agbayani, M-J, Boddington, D, Chao, T-F, Johar, S, John, B, Joung, B, Krishinan, S, Krittayaphong, R, Kurokawa, S, Lau, C-P, Lim, TW, Pham, TL, Vien, HL, Naik, A, Okumura, Y, Sasano, T, Yan, B, Raharjo, SB, Hanafy, DA, Yuniadi, Y, Nwe, N, Awan, ZA, Huang, H, and Freedman, B

Abstract

In this paper, the Asia Pacific Heart Rhythm Society (APHRS) sought to provide practice guidance on AF screening based on recent evidence, with specific considerations relevant to the Asia-Pacific region. A key recommendation is opportunistic screening for people aged ≥65 years (all countries), with systematic screening to be considered for people aged ≥75 years or who have additional risk factors (all countries).

Published
2022

2. Management and 1-year outcomes of patients with newly diagnosed atrial fibrillation and chronic kidney disease: Results from the prospective garfield-af registry

Author

Goto, S, Angchaisuksiri, P, Bassand, JP, John Camm, A, Dominguez, H, Illingworth, L, Gibbs, H, Goldhaber, SZ, Jing, ZC, Haas, S, Kayani, G, Koretsune, Y, Lim, TW, Oh, S, Sawhney, JPS, Turpie, AGG, van Eickels, M, Verheugt, FWA, Kakkar, AK, Fitzmaurice, DA, Hacke, W, Mantovani, LG, Misselwitz, F, Pieper, KS, Fox, KAA, Gersh, BJ, Luciardi, HL, Brodmann, M, Cools, F, Barretto, ACP, Connolly, SJ, Spyropoulos, A, Eikelboom, J, Corbalan, R, Hu, D, Jansky, P, Nielsen, JD, Ragy, H, Raatikainen, P, Le Heuzey, JY, Darius, H, Keltai, M, Kakkar, S, Agnelli, G, Ambrosio, G, Díaz, CJS, Ten Cate, H, Atar, D, Stepinska, J, Panchenko, E, Jacobson, B, Viñolas, X, Rosenqvist, M, Steffel, J, Oto, A, Parkhomenko, A, Al Mahmeed, W, Hu, DY, Chen, KN, Zhao, YS, Zhang, HQ, Chen, JZ, Cao, SP, Wang, DW, Yang, YJ, Li, WH, Yin, YH, Tao, GZ, Yang, P, Chen, YM, He, SH, Wang, Y, Fu, GS, Li, X, Wu, TG, Cheng, XS, Yan, XW, Zhao, RP, Chen, MS, Xiong, LG, Chen, P, Jiao, Y, Guo, Y, Xue, L, Wang, FZ, Li, H, Yang, ZM, Bai, CL, Chen, J, Chen, JY, Chen, X, Feng, S, Fu, QH, Gao, XJ, Guo, WN, He, RH, He, XA, Hu, XS, Juergens, Craig ; https://orcid.org/0000-0002-5935-8619, Goto, S, Angchaisuksiri, P, Bassand, JP, John Camm, A, Dominguez, H, Illingworth, L, Gibbs, H, Goldhaber, SZ, Jing, ZC, Haas, S, Kayani, G, Koretsune, Y, Lim, TW, Oh, S, Sawhney, JPS, Turpie, AGG, van Eickels, M, Verheugt, FWA, Kakkar, AK, Fitzmaurice, DA, Hacke, W, Mantovani, LG, Misselwitz, F, Pieper, KS, Fox, KAA, Gersh, BJ, Luciardi, HL, Brodmann, M, Cools, F, Barretto, ACP, Connolly, SJ, Spyropoulos, A, Eikelboom, J, Corbalan, R, Hu, D, Jansky, P, Nielsen, JD, Ragy, H, Raatikainen, P, Le Heuzey, JY, Darius, H, Keltai, M, Kakkar, S, Agnelli, G, Ambrosio, G, Díaz, CJS, Ten Cate, H, Atar, D, Stepinska, J, Panchenko, E, Jacobson, B, Viñolas, X, Rosenqvist, M, Steffel, J, Oto, A, Parkhomenko, A, Al Mahmeed, W, Hu, DY, Chen, KN, Zhao, YS, Zhang, HQ, Chen, JZ, Cao, SP, Wang, DW, Yang, YJ, Li, WH, Yin, YH, Tao, GZ, Yang, P, Chen, YM, He, SH, Wang, Y, Fu, GS, Li, X, Wu, TG, Cheng, XS, Yan, XW, Zhao, RP, Chen, MS, Xiong, LG, Chen, P, Jiao, Y, Guo, Y, Xue, L, Wang, FZ, Li, H, Yang, ZM, Bai, CL, Chen, J, Chen, JY, Chen, X, Feng, S, Fu, QH, Gao, XJ, Guo, WN, He, RH, He, XA, Hu, XS, and Juergens, Craig ; https://orcid.org/0000-0002-5935-8619

Abstract

Background-—Using data from the GARFIELD-AF (Global Anticoagulant Registry in the FIELD–Atrial Fibrillation), we evaluated the impact of chronic kidney disease (CKD) stage on clinical outcomes in patients with newly diagnosed atrial fibrillation (AF). Methods and Results-—GARFIELD-AF is a prospective registry of patients from 35 countries, including patients from Asia (China, India, Japan, Singapore, South Korea, and Thailand). Consecutive patients enrolled (2013–2016) were classified with no, mild, or moderate-to-severe CKD, based on the National Kidney Foundation’s Kidney Disease Outcomes Quality Initiative guidelines. Data on CKD status and outcomes were available for 33 024 of 34 854 patients (including 9491 patients from Asia); 10.9% (n=3613) had moderate-to-severe CKD, 16.9% (n=5595) mild CKD, and 72.1% (n=23 816) no CKD. The use of oral anticoagulants was influenced by stroke risk (ie, post hoc assessment of CHA2DS2-VASc score), but not by CKD stage. The quality of anticoagulant control with vitamin K antagonists did not differ with CKD stage. After adjusting for baseline characteristics and antithrombotic use, both mild and moderate-to-severe CKD were independent risk factors for all-cause mortality. Moderate-to-severe CKD was independently associated with a higher risk of stroke/systemic embolism, major bleeding, new-onset acute coronary syndrome, and new or worsening heart failure. The impact of moderate-to-severe CKD on mortality was significantly greater in patients from Asia than the rest of the world (P=0.001). Conclusions-—In GARFIELD-AF, moderate-to-severe CKD was independently associated with stroke/systemic embolism, major bleeding, and mortality. The effect of moderate-to-severe CKD on mortality was even greater in patients from Asia than the rest of the world.

Published
2019

3. Denial of long-term issues with agriculture on tropical peatlands will have devastating consequences

Author

Wijedasa, LS, Jauhiainen, J, Kononen, M, Lampela, M, Vasander, H, Leblanc, MC, Evers, S, Smith, TEL, Yule, CM, Varkkey, H, Lupascu, M, Parish, F, Singleton, I, Clements, GR, Aziz, SA, Harrison, ME, Cheyne, S, Anshari, GZ, Meijaard, E, Goldstein, JE, Waldron, S, Hergoualc'h, K, Dommain, R, Frolking, S, Evans, CD, Posa, MRC, Glaser, PH, Suryadiputra, N, Lubis, R, Santika, T, Padfield, R, Kurnianto, S, Hadisiswoyo, P, Lim, TW, Page, SE, Gauci, V, Van der Meer, PJ, Buckland, H, Garnier, F, Samuel, MK, Choo, LNLK, O'Reilly, P, Warren, M, Suksuwan, S, Sumarga, E, Jain, A, Laurance, WF, Couwenberg, J, Joosten, H, Vernimmen, R, Hooijer, A, Malins, C, Cochrane, MA, Perumal, B, Siegert, F, Peh, KSH, Corneau, LP, Verchot, L, Harvey, CF, Cobb, A, Jaafar, Z, Wosten, H, Manuri, S, Muller, M, Giesen, W, Phelps, J, Yong, DL, Silvius, M, Wedeux, BMM, Hoyt, A, Osaki, M, Hirano, T, Takahashi, H, Kohyama, TS, Haraguchi, A, Nugroho, NP, Coomes, DA, Quoi, LP, Dohong, A, Gunawan, H, Gaveau, DLA, Langner, A, Lim, FKS, Edwards, DP, Giam, X, Van der Werf, G, Carmenta, R, Verwer, CC, Gibson, L, Grandois, L, Graham, LLB, Regalino, J, Wich, SA, Rieley, J, Kettridge, N, Brown, C, Pirard, R, Moore, S, Capilla, BR, Ballhorn, U, Ho, HC, Hoscilo, A, Lohberger, S, Evans, TA, Yulianti, N, Blackham, G, Onrizal, Husson, S, Murdiyarso, D, Pangala, S, Cole, LES, Tacconi, L, Segah, H, Tonoto, P, Lee, JSH, Schmilewski, G, Wulffraat, S, Putra, EI, Cattau, ME, Clymo, RS, Morrison, R, Mujahid, A, Miettinen, J, Liew, SC, Valpola, S, Wilson, D, D'Arcy, L, Gerding, M, Sundari, S, Thornton, SA, Kalisz, B, Chapman, SJ, Su, ASM, Basuki, I, Itoh, M, Traeholt, C, Sloan, S, Sayok, AK, Andersen, R, Wijedasa, LS, Jauhiainen, J, Kononen, M, Lampela, M, Vasander, H, Leblanc, MC, Evers, S, Smith, TEL, Yule, CM, Varkkey, H, Lupascu, M, Parish, F, Singleton, I, Clements, GR, Aziz, SA, Harrison, ME, Cheyne, S, Anshari, GZ, Meijaard, E, Goldstein, JE, Waldron, S, Hergoualc'h, K, Dommain, R, Frolking, S, Evans, CD, Posa, MRC, Glaser, PH, Suryadiputra, N, Lubis, R, Santika, T, Padfield, R, Kurnianto, S, Hadisiswoyo, P, Lim, TW, Page, SE, Gauci, V, Van der Meer, PJ, Buckland, H, Garnier, F, Samuel, MK, Choo, LNLK, O'Reilly, P, Warren, M, Suksuwan, S, Sumarga, E, Jain, A, Laurance, WF, Couwenberg, J, Joosten, H, Vernimmen, R, Hooijer, A, Malins, C, Cochrane, MA, Perumal, B, Siegert, F, Peh, KSH, Corneau, LP, Verchot, L, Harvey, CF, Cobb, A, Jaafar, Z, Wosten, H, Manuri, S, Muller, M, Giesen, W, Phelps, J, Yong, DL, Silvius, M, Wedeux, BMM, Hoyt, A, Osaki, M, Hirano, T, Takahashi, H, Kohyama, TS, Haraguchi, A, Nugroho, NP, Coomes, DA, Quoi, LP, Dohong, A, Gunawan, H, Gaveau, DLA, Langner, A, Lim, FKS, Edwards, DP, Giam, X, Van der Werf, G, Carmenta, R, Verwer, CC, Gibson, L, Grandois, L, Graham, LLB, Regalino, J, Wich, SA, Rieley, J, Kettridge, N, Brown, C, Pirard, R, Moore, S, Capilla, BR, Ballhorn, U, Ho, HC, Hoscilo, A, Lohberger, S, Evans, TA, Yulianti, N, Blackham, G, Onrizal, Husson, S, Murdiyarso, D, Pangala, S, Cole, LES, Tacconi, L, Segah, H, Tonoto, P, Lee, JSH, Schmilewski, G, Wulffraat, S, Putra, EI, Cattau, ME, Clymo, RS, Morrison, R, Mujahid, A, Miettinen, J, Liew, SC, Valpola, S, Wilson, D, D'Arcy, L, Gerding, M, Sundari, S, Thornton, SA, Kalisz, B, Chapman, SJ, Su, ASM, Basuki, I, Itoh, M, Traeholt, C, Sloan, S, Sayok, AK, and Andersen, R

Abstract

Letter

Published
2017

4. Percutaneous microwave ablation with a long side-firing antenna array can successfully treat a nonsurgical chronic ovine atrial flutter model

Author

Lim, TW, Clout, R, Barry, MA, Lu, J, Huang, K, Thomas, SP, Lim, TW, Clout, R, Barry, MA, Lu, J, Huang, K, and Thomas, SP

Abstract

Microwave Ablation of an Ovine Atrial Flutter Model. Introduction: Long side-firing microwave (MW) arrays can deliver energy uniformly over its length without the need for intimate endocardial contact. We hypothesize that a novel 6 Fr 20 mm long percutaneous high-efficiency MW antenna array ablation catheter can rapidly create long, continuous, and transmural linear ablation lesions. Methods and Results: Cavotricuspid isthmus (CTI)-dependent atrial flutter (AFL) was created in 11 sheep by a line of radiofrequency ablation lesions in the posterior right atrium (RA) linking the venae cavae. After 4-6 weeks recovery, CTI-dependent AFL was still inducible in all 11 sheep (cycle length 178 ± 13 ms). MW ablation of the CTI at 100 W for 30 seconds was then performed with an endpoint of AFL noninducibility. AFL was not inducible in all 11 sheep after 4.3 ± 3.3 MW applications (129 ± 99 seconds). The last 6 animals needed fewer ablations (2.2 ± 1.5) and 3 of these sheep required only a single ablation. Although conduction times from proximal coronary sinus to lateral RA and vice versa increased postablation (51 ± 14 ms to 118 ± 31 ms [P = 0.0002] and 60 ± 13 ms to 119 ± 28 ms [P = 0.0001], respectively), AFL was still inducible in 2 sheep and further ablation was needed to reach the endpoint. Conclusions: High-efficiency side-firing MW array ablation can rapidly create long linear and electrically intact lesions in an ovine AFL model. AFL noninducibility may be a more reliable indicator than CTI conduction times of an intact line of ablation in this animal model. © 2009 Wiley Periodicals, Inc.

Published
2009

5. Percutaneous microwave ablation with a long side-firing antenna array can successfully treat a nonsurgical chronic ovine atrial flutter model

Author

Lim, TW, Clout, R, Barry, MA, Lu, J, Huang, K, Thomas, SP, Lim, TW, Clout, R, Barry, MA, Lu, J, Huang, K, and Thomas, SP

Abstract

Microwave Ablation of an Ovine Atrial Flutter Model. Introduction: Long side-firing microwave (MW) arrays can deliver energy uniformly over its length without the need for intimate endocardial contact. We hypothesize that a novel 6 Fr 20 mm long percutaneous high-efficiency MW antenna array ablation catheter can rapidly create long, continuous, and transmural linear ablation lesions. Methods and Results: Cavotricuspid isthmus (CTI)-dependent atrial flutter (AFL) was created in 11 sheep by a line of radiofrequency ablation lesions in the posterior right atrium (RA) linking the venae cavae. After 4-6 weeks recovery, CTI-dependent AFL was still inducible in all 11 sheep (cycle length 178 ± 13 ms). MW ablation of the CTI at 100 W for 30 seconds was then performed with an endpoint of AFL noninducibility. AFL was not inducible in all 11 sheep after 4.3 ± 3.3 MW applications (129 ± 99 seconds). The last 6 animals needed fewer ablations (2.2 ± 1.5) and 3 of these sheep required only a single ablation. Although conduction times from proximal coronary sinus to lateral RA and vice versa increased postablation (51 ± 14 ms to 118 ± 31 ms [P = 0.0002] and 60 ± 13 ms to 119 ± 28 ms [P = 0.0001], respectively), AFL was still inducible in 2 sheep and further ablation was needed to reach the endpoint. Conclusions: High-efficiency side-firing MW array ablation can rapidly create long linear and electrically intact lesions in an ovine AFL model. AFL noninducibility may be a more reliable indicator than CTI conduction times of an intact line of ablation in this animal model. © 2009 Wiley Periodicals, Inc.

Published
2009

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