1. Implications of early respiratory support strategies on disease progression in critical COVID-19
- Author
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RISC-19-ICU Investigators, Pedro D. Wendel Garcia, Hernán Aguirre-Bermeo, Philipp K. Buehler, Mario Alfaro-Farias, Bernd Yuen, Sascha David, Thomas Tschoellitsch, Tobias Wengenmayer, Anita Korsos, Alberto Fogagnolo, Gian Reto Kleger, Maddalena A. Wu, Riccardo Colombo, Fabrizio Turrini, Antonella Potalivo, Emanuele Rezoagli, Raquel Rodríguez-García, Pedro Castro, Arantxa Lander-Azcona, Maria C. Martín-Delgado, Herminia Lozano-Gómez, Rolf Ensner, Marc P. Michot, Nadine Gehring, Peter Schott, Martin Siegemund, Lukas Merki, Jan Wiegand, Marie M. Jeitziner, Marcus Laube, Petra Salomon, Frank Hillgaertner, Alexander Dullenkopf, Hatem Ksouri, Sara Cereghetti, Serge Grazioli, Christian Bürkle, Julien Marrel, Isabelle Fleisch, Marie Helene Perez, Anja Baltussen Weber, Samuele Ceruti, Katharina Marquardt, Tobias Hübner, Hermann Redecker, Michael Studhalter, Michael Stephan, D.A.M.P.J. (Diederik) Gommers, C (Can) Ince, G (Giovanni) Vitale, RISC-19-ICU Investigators, Pedro D. Wendel Garcia, Hernán Aguirre-Bermeo, Philipp K. Buehler, Mario Alfaro-Farias, Bernd Yuen, Sascha David, Thomas Tschoellitsch, Tobias Wengenmayer, Anita Korsos, Alberto Fogagnolo, Gian Reto Kleger, Maddalena A. Wu, Riccardo Colombo, Fabrizio Turrini, Antonella Potalivo, Emanuele Rezoagli, Raquel Rodríguez-García, Pedro Castro, Arantxa Lander-Azcona, Maria C. Martín-Delgado, Herminia Lozano-Gómez, Rolf Ensner, Marc P. Michot, Nadine Gehring, Peter Schott, Martin Siegemund, Lukas Merki, Jan Wiegand, Marie M. Jeitziner, Marcus Laube, Petra Salomon, Frank Hillgaertner, Alexander Dullenkopf, Hatem Ksouri, Sara Cereghetti, Serge Grazioli, Christian Bürkle, Julien Marrel, Isabelle Fleisch, Marie Helene Perez, Anja Baltussen Weber, Samuele Ceruti, Katharina Marquardt, Tobias Hübner, Hermann Redecker, Michael Studhalter, Michael Stephan, D.A.M.P.J. (Diederik) Gommers, C (Can) Ince, and G (Giovanni) Vitale
- Abstract
Background: Uncertainty about the optimal respiratory support strategies in critically ill COVID-19 patients is widespread. While the risks and benefits of noninvasive techniques versus early invasive mechanical ventilation (IMV) are intensely debated, actual evidence is lacking. We sought to assess the risks and benefits of different respiratory support strategies, employed in intensive care units during the first months of the COVID-19 pandemic on intubation and intensive care unit (ICU) mortality rates. Methods: Subanalysis of a prospective, multinational registry of critically ill
- Published
- 2021
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