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BOOK abstract: This book brings together conceptual and empirical insights to explore the interconnections between social networks based on Information and Communication Technologies (ICT) and travel behaviour in urban environments. Over the past decade, rapid development of ICT has led to extensive social impacts and influence on travel and mobility patterns within urban spaces. A new field of research of digital social networks and travel behaviour is now emerging. This book presents state-of-the-art knowledge, cutting-edge research and integrated analysis methods from the fields of social networks, travel behaviour and urban analysis. It explores the challenges related to the question of how we can synchronize among social networks activities, transport means, intelligent communication/information technologies and the urban form. This innovative book encourages multidisciplinary insights and fusion among three disciplines of social networks, travel behaviour and urban analysis. It offers new horizons for research and will be of interest to students and scholars studying mobilities, transport studies, urban geography, urban planning, the built environment and urban policy. ABSTRACT Chapter : Our opinions and beliefs are increasingly affected by social media. Within a network, opinions possibly drive community/ies towards essential choices.We analyze how to model the dynamic process of updating opinions based on the opinions of neighbours and, indirectly, on other individual opinions. We will consider the case of attention to the neighbour behaviour that is invariant over time and the (methodologically) harder case in which attention towards others changes according to unexpected events that may occur. Also, opinion dynamics, investigating the fusion process of the opinion formation, is a powerful tool for supporting the management of public opinion. We will focus on opinion formation among individuals and the resulting dynamics it induces in a social network. Afte

BOOK abstract: This book brings together conceptual and empirical insights to explore the interconnections between social networks based on Information and Communication Technologies (ICT) and travel behaviour in urban environments. Over the past decade, rapid development of ICT has led to extensive social impacts and influence on travel and mobility patterns within urban spaces. A new field of research of digital social networks and travel behaviour is now emerging. This book presents state-of-the-art knowledge, cutting-edge research and integrated analysis methods from the fields of social networks, travel behaviour and urban analysis. It explores the challenges related to the question of how we can synchronize among social networks activities, transport means, intelligent communication/information technologies and the urban form. This innovative book encourages multidisciplinary insights and fusion among three disciplines of social networks, travel behaviour and urban analysis. It offers new horizons for research and will be of interest to students and scholars studying mobilities, transport studies, urban geography, urban planning, the built environment and urban policy. ABSTRACT Chapter : Our opinions and beliefs are increasingly affected by social media. Within a network, opinions possibly drive community/ies towards essential choices.We analyze how to model the dynamic process of updating opinions based on the opinions of neighbours and, indirectly, on other individual opinions. We will consider the case of attention to the neighbour behaviour that is invariant over time and the (methodologically) harder case in which attention towards others changes according to unexpected events that may occur. Also, opinion dynamics, investigating the fusion process of the opinion formation, is a powerful tool for supporting the management of public opinion. We will focus on opinion formation among individuals and the resulting dynamics it induces in a social network. Afte

5-Azacytidine is an effective therapy in high risk MDS and oligoblastic AML. This "real life" analysis was made on 185 patients treated with 5-azacytidine in 10 centers afferent to REL ("Rete Ematologica Lombarda"), a network in Lombardia region. The aim was to assess the influence of disease and comorbidity risk assessments on the survival. The results confirm the utility of 5-azacitidine in prolonging OS regardless of advanced age and the presence of comorbidities. They also encourage an early treatment since patients with IPSS-R High risk MDS have better outcome with respect to Very High risk ones. According to the IPSS cytogenetic risk, there was no difference in the outcome between Intermediate and High risk patients. Nevertheless, a poorer cytogenetic risk, according to the IPSS-R cytogenetic stratification, negatively influenced the outcome.

With the advent of an operational Space Transportation System, many opportunities for activities in space exist. Maintenance of on-orbit satellite systems is one such application. Planners need techniques to evaluate the appropriate maintenance category; i.e., whether a preventive maintenance program is feasible or should a corrective maintenance scheme be applied. This study demonstrates a simple yet technically accurate graphical estimating methodology, known as the Total-Time-on-Test plot. Specifically, using this technique in conjunction with on-orbit life data from Traveling Wave Tube Assemblies located aboard second generation Defense Satellite Communications System (DSCS-II) and North Atlantic Treaty Organization Phase III (NATO III) satellites, preventive maintenance on these items is shown not to be the method of choice. Further, techniques are demonstrated for determining estimated optimal maintenance intervals using failure and repair costs should preventive maintenance be demonstrated as a feasible maintenance category. (Author)

Des prospections subaquatiques menées dans la Charente, sur le site de Taillebourg – Port d’Envaux (17), ont révélé la présence de nombreux témoins d’activités liés au fleuve Charente, datés principalement des périodes mérovingienne et carolingienne. Parmi l’abondant mobilier découvert figure un lot d’objets en plomb.Ces plombs ont été trouvés dans un contexte de pratiques halieutiques. Les premières interprétations les définissent comme des lests d’engins de pêche. La découverte d’un tel corpus est déjà en soi un fait intéressant. En effet, la facilité de recyclage de ce matériau de plaide pas pour sa conservation. L’étude de ce matériel a porté à la fois sur la définition de leur typologie et une première interprétation de leur fonction. En plus des méthodes de classement habituellement utilisées, une approche expérimentale a été menée pour mieux appréhender les techniques de mise en forme utilisées. Des analyses de surface par fluorescence X ont pu être également réalisées. Enfin, le contexte chronologique plaçant cette collection au haut Moyen Âge et la découverte de ce matériel dans la zone d’influence de l’atelier monétaire de Melle nous ont conduit à poser la question de l’origine du plomb métal. Pour répondre à cette interrogation, une série d’analyses isotopique du plomb a été réalisée à partir de la série des plombs naviformes., Subaquaeous surveys carried out in the Charente, on the site Taillebourg – Port Envaux (dept. Charente-Maritime, France) revealed the presence of many evidences in activities related to river Charente, dating mainly from Merovingian and Carolingian periods. A lot of lead objects is found among the abundant furniture.These leads were found in a context of fishing practices. The first interpretations defined as fishing gear. The discovery of such a corpus is itself an interesting fact. Indeed, the tendency of recycling this material does not plead for its preservation. The study of these sinkers has focused both on the definition of their type and initial interpretation of their function. In addition to classified methods usually used, an experimental approach was undertaken to better understand the techniques of production. Surface analysis by X-ray fluorescence were also performed. Finally, the historical context, placing the collection in the High Middle Ages and the discovery of this material in the zone of influence of the mint of Melle led us to the question of the origin of lead metal. To answer this question, a series of lead isotope analysis was carried out from the series of boat-form leads.