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Fungal infections have been increasing in recent years due to a growing number of high-risk patients, particularly immunocompromised hosts. Currently, medicinal plants are known for their properties due to their essential oils and phenolic compounds. They have been empirically used as antimicrobial agents. So the composition of the phenolic extracts and essential oils of Myrtus communis and Zygophyllum album and their antifungal activity on Candida albicans, Aspergillus fumigatus fungal strains were studied. In this fact, essential oils from the aerial parts of the plant were obtained by hydrodistillation and analyzed by GC and GC-MS, for the phenolic extracts, several extraction methods with a preliminary phytochemical study were applied. The oils showed high contents of α-pinene and cineol for M. communis and verbenone and caryophyllene for the Z. album. The MIC and minimal lethal concentration were used to evaluate the antifungal activity against Candida and Aspergillus strains. Results showed that M. communis and Z. album essential oil and phenolic extracts exhibited a significant activity against clinically relevant fungi, a significant antifungal activity of the two extracts studied (MCA and ZAM) was observed on C. albicans of these, two extracts, MCA was found to be most active with an MFC value of 25 mg/ml versus 100 mg/ml for ZAM. Nevertheless, the essential oils exhibited stronger antifungal activity than the phenolic extracts. The present study indicates that the two medicinal plants have considerable antifungal activity, deserving further investigation for clinical applications. DOI: http://dx.doi.org/10.5281/zenodo.3751202

Micro-organisms do not always exist in planctonic forms (single cells or small groups). To survive, especially in limiting media, they may adhere to inert or living surfaces. This enables them to multiply within a community protected by an extracellular matrix, thus forming a biofilm which protects them from antimicrobials especially antibiotics. In this paper, the aim of this study was to investigate autoaggregation, co-aggragation, surface hydrophobicity and exopolysaccharides production of different pathogenic bacteria treated with methanolic, hydro-methanolic and aqueous extract of Mentha viridis collected in El Bayadh (South West of Algeria). The qualitative analysis revealed the presence of polyphenols and flavonoids, which were confirmed-by-quantitative-analysis. All extracts showed an antibacterial activity (antiadhesiveness).The percentage of autoaggregation, coaggregation decreased in presence of extract comparing to control. E.coli was hydrophobic while the others hydrophilic. The amount of exopolysaccharides (EPS) produces by bacteria decreased considerably with all extracts comparatively to control (without extracts).

Micro-organisms do not always exist in planctonic forms (single cells or small groups). To survive, especially in limiting media, they may adhere to inert or living surfaces. This enables them to multiply within a community protected by an extracellular matrix, thus forming a biofilm which protects them from antimicrobials especially antibiotics. In this paper, the aim of this study was to investigate autoaggregation, co-aggragation, surface hydrophobicity and exopolysaccharides production of different pathogenic bacteria treated with methanolic, hydro-methanolic and aqueous extract of Mentha viridis collected in El Bayadh (South West of Algeria). The qualitative analysis revealed the presence of polyphenols and flavonoids, which were confirmed-by-quantitative-analysis. All extracts showed an antibacterial activity (antiadhesiveness).The percentage of autoaggregation, coaggregation decreased in presence of extract comparing to control. E.coli was hydrophobic while the others hydrophilic. The amount of exopolysaccharides (EPS) produces by bacteria decreased considerably with all extracts comparatively to control (without extracts).