1. Systemic vasculitis: one year in review 2023
- Author
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Moretti, M, Treppo, E, Monti, S, La Rocca, G, Del Frate, G, Delvino, P, Italiano, N, Di Cianni, F, D'Alessandro, F, Talarico, R, Ferro, F, Quartuccio, L, Baldini, C, Michele Moretti, Elena Treppo, Sara Monti, Gaetano La Rocca, Giulia Del Frate, Paolo Delvino, Nazzareno Italiano, Federica Di Cianni, Francesco D'Alessandro, Rosaria Talarico, Francesco Ferro, Luca Quartuccio, Chiara Baldini, Moretti, M, Treppo, E, Monti, S, La Rocca, G, Del Frate, G, Delvino, P, Italiano, N, Di Cianni, F, D'Alessandro, F, Talarico, R, Ferro, F, Quartuccio, L, Baldini, C, Michele Moretti, Elena Treppo, Sara Monti, Gaetano La Rocca, Giulia Del Frate, Paolo Delvino, Nazzareno Italiano, Federica Di Cianni, Francesco D'Alessandro, Rosaria Talarico, Francesco Ferro, Luca Quartuccio, and Chiara Baldini
- Abstract
Systemic vasculitides are heterogeneous disabling diseases characterised by chronic inflammation of the blood vessels potentially leading to tissue destruction and organ failure. The recent COVID-19 pandemic has had a significant impact on the epidemiology and management of patients with systemic vasculitis. In parallel, new insights have been provided on systemic vasculitis pathogenetic mechanisms, possible new therapeutic targets, and newer glucocorticoid-sparing treatments with better safety profiles. As in the previous annual reviews of this series, in this review we will provide a critical digest of the most recent literature regarding pathophysiology, clinical manifestations, diagnostic tools and treatment options in small- and large-vessel vasculitis focusing on precision medicine in vasculitis.
- Published
- 2023