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The removal of alveolar bone and periodontal ligament due to periodontal disease often requires a surgical approach to remodel the biological construction and functions of the periodontium. Hydrogel, a functional polymeric material, has become a promising technology for periodontal disease therapies. It has the plurality of mimicking the extracellular matrix and providing suitable attachment sites and growth environments for periodontal cells, with high biocompatibility, water retention and slow release. A review of the last 5 years of the literature has been made, where we have summarized the main components of the hydrogel in the regeneration of periodontal tissue., La eliminación del hueso alveolar y el ligamento periodontal gracias a la enfermedad periodontal a menudo requiere un abordaje quirúrgico para remodelar la construcción biológica y las funciones del periodonto. El hidrogel, un material polimérico funcional, se ha transformado en una tecnología prometedora para terapias de enfermedades periodontales. Tiene la pluralidad de imitar la matriz extracelular y proporcionar sitios de unión adecuados y entornos de crecimiento para las células periodontales, con alta biocompatibilidad, retención de agua y liberación lenta. Se ha hecho una revisión de los últimos 5 años en lo que va de la literatura, donde hemos resumido los principales componentes del hidrogel en la regeneración del tejido periodontal.

The advancement of bone tissue engineering offers a new approach for the repairing bone defects. Among those crucials in this field is the scaffold material. In this study, the transformed-hydroxyapatite is made from the cuttlebone through hydrothermal reactions and the feasibility of using it as the scaffold material in bone tissue engineering was observed.