1. Tuberculosis Molecular Bacterial Load Assay Reveals Early Delayed Bacterial Killing in Patients With Relapse.
- Author
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Ntinginya, Nyanda Elias, Ntinginya, Nyanda Elias, Bakuli, Abhishek, Mapamba, Daniel, Sabiiti, Wilber, Kibiki, Gibson, Minja, Lilian Tina, Kuchaka, Davis, Reither, Klaus, Phillips, Patrick Peter John, Boeree, Martin Johan, Gillespie, Stephen H, Hoelscher, Michael, Heinrich, Norbert, Pan African Consortium for the Evaluation of Antituberculosis Antibiotics (PanACEA) Consortium, Ntinginya, Nyanda Elias, Ntinginya, Nyanda Elias, Bakuli, Abhishek, Mapamba, Daniel, Sabiiti, Wilber, Kibiki, Gibson, Minja, Lilian Tina, Kuchaka, Davis, Reither, Klaus, Phillips, Patrick Peter John, Boeree, Martin Johan, Gillespie, Stephen H, Hoelscher, Michael, Heinrich, Norbert, and Pan African Consortium for the Evaluation of Antituberculosis Antibiotics (PanACEA) Consortium
- Abstract
Bacterial killing in patients with tuberculosis (TB) relapse was compared to that in patients achieving cure, measured by TB molecular bacterial load assay (TB-MBLA) or mycobacteria growth indicator tube (MGIT) time to positivity (TTP). TB-MBLA in 4 relapsed patients was significantly different compared to 132 cured patients after 2 weeks of treatment; MGIT TTP showed a significant difference from week 8.
- Published
- 2023