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The aim of this study was clinical testing of the reliability and usability of three-dimensional (3D) and two-dimensional (2D) ultrasound (US) technology. The ultimate aim and purpose of this study was to establish ultrasound methods, standards and protocols for determining the volume of any gynecologic organ or tumor. The study included 31 women in reproductive age and postmenopause. All patients were examined with a RIC 5-9 3D-endovaginal probe (4.3-7.5 MHz) on a Voluson 730 Pro ultrasound device. The volume of myomas was measured by using the existing 2D and 3D ultrasound methods on the above mentioned device. All patients underwent myomectomy or hysterectomy due to clinically and ultrasonographically diagnosed uterine myomas indicating operative intervention. After the operation, the pathologist determined the volume of removed myomas by measuring them in a gauge bowl containing water, i.e. using Archimedes' principle (lift), serving as the control group with histopathologic diagnosis. A total of 155 myoma volumes were processed on 2D display, 31 myoma volumes were preoperatively measured on 3D display and 31 myoma volumes were measured by the pathologist. The values of US measurements for each US method were expressed as mean value of all measurements of myoma volumes. Statistical processing of the results and Student's t-test for independent samples revealed that the 2nd examined US method (measuring of myoma by using an ellipse and the longer tumor diameter) and 4th examined US method (measuring of myoma by using the longer and shorter tumor diameters together with establishing their mean values) in 2D US technique, as well as the 6th examined US method in 3D US technique showed no significant measurement differences in comparison with control measurement in a gauge bowl containing water (p < 0.05), indicating acceptability of the US methods for verifying tumor volumes. The standard error in determining the volume of myomas by the above US methods varied between 15% and 25%, so it is concluded that these three methods can be used in clinical practice to determine tumor volumes, in this case uterine myomas. The 3D MultiPlane method proved to be the most reliable method of determining the volume of uterine myomas.

Ugovor o funkcioniranju Europske unije predviđa da svatko tko je pretrpio štetu, bilo da je ona rezultat nametanja nepoštenih kupovnih ili prodajnih cijena što najčešće omogućuje monopolska pozicija te zbog drugih nepoštenih trgovinskih uvjeta, ima pravo na naknadu za stvarno pretrpjeli gubitak, izgubljenu dobit i kamate. Praktičnim vodičem za kvantificiranje štete u postupcima za naknadu štete Europska komisija preporučuje korištenje poredbene metode, simulacijskih modela, troškovne i financijske analize i druge metode. U okviru poredbene metode predlaže sofisticirano usklađivanje poredbenih podataka koje se može dobiti na temelju ekonometrijskih tehnika, konkretno primjenom analize regresije. U skladu s navedenim preporukama u radu je korišten regresijski model koji je omogućio na temelju raspoloživih podataka utvrditi kolika je izgubljena dobit u poduzeću kojem je dobavljač neosnovano povisio cijenu sirovine. Analiza je obuhvatila financijske podatke iz prethodnih godina radi utvrđivanja utječe li povećanje cijena na ostvareni prihod, na ostvarenu dobit i koliko ulazni trošak utječe na ostvareni financijski rezultat.