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15 results on '"Abacar, K."'

2. A cross‐sectional study on activity impairment in primary Sjogren's syndrome

Author

Yıldız Yenissoy, Elif Naz Altıngöz, Aysun Kapusuz, Kerem Abacar, Imren Tatlı, Filiz Türe‐Özdemir, Umit Karacaylı, Meral Yay, Haner Direskeneli, Farida Fortune, Nevsun Inanc, Gonca Mumcu, and Yenissoy Y., Altıngöz E. N., Kapusuz A., Abacar K., Tatlı I., Türe-Özdemir F., Karacaylı U., Yay M., Direskeneli H., Fortune F., et al.

Subjects
Otorhinolaryngology, General Dentistry
Published
2023

3. Re: Risk of hbv reactivation in hbsag negative and antihbc igg positive patients receiving biologic therapy

Author

KANİ, HALUK TARIK, KARABACAK, MURAT, CÖMERT ÖZER, ELİF, ABACAR, KEREM YİĞİT, KUTLUĞ AĞAÇKIRAN, SEDA, SEVİK, GİZEM, ALİBAZ ÖNER, FATMA, İNANÇ, GÜZİDE NEVSUN, ATAGÜNDÜZ, MEHMET PAMİR, ÖZEN ALAHDAB, YEŞİM, DİRESKENELİ, RAFİ HANER, ATUĞ, ÖZLEN, and Ergenç İ., KANİ H. T., KARABACAK M., CÖMERT ÖZER E., Mehdiyev S., Jafarov F., ABACAR K. Y., KUTLUĞ AĞAÇKIRAN S., SEVİK G., Aslan R., et al.

Subjects
Internal Diseases, Internal Medicine Sciences, Klinik Tıp, GASTROENTEROLOGY & HEPATOLOGY, Gastroenterology, Dahili Tıp Bilimleri, Gastroenterology and Hepatology, CLINICAL MEDICINE, Sağlık Bilimleri, İç Hastalıkları, GASTROENTEROLOJİ VE HEPATOLOJİ, Clinical Medicine (MED), Tıp, Gastroenteroloji, Gastroenteroloji-(Hepatoloji), Health Sciences, Medicine, Klinik Tıp (MED)
Published
2023

4. Exosomes' profile in ankylosing spondylitis: A preliminary study

Author

ABACAR, KEREM YİĞİT, ATAGÜNDÜZ, MEHMET PAMİR, ERZİK, CAN, and Karakaya E., Deniz R., ABACAR K. Y., ATAGÜNDÜZ M. P., ERZİK C.

Subjects
Temel Tıp Bilimleri, Medicine (miscellaneous), Assessment and Diagnosis, Sağlık Bilimleri, Temel Bilgi ve Beceriler, Genel Tıp, Fundamental Medical Sciences, Pathophysiology, Clinical Medicine (MED), TIP, GENEL & DAHİLİ, Health Sciences, ankylosing spondylitis, Internal Medicine, Klinik Tıp (MED), Aile Sağlığı, MEDICINE, GENERAL & INTERNAL, Dahiliye, Patofizyoloji, Klinik Tıp, Fundamentals and Skills, General Medicine, CLINICAL MEDICINE, Değerlendirme ve Teşhis, Tıp, Exosome, cell surface markers, General Health Professions, Medicine, Tıp (çeşitli), extracellular vesicle, Family Practice, Genel Sağlık Meslekleri
Abstract

Objective: Ankylosing spondylitis (AS) is a chronic systemic inflammatory disease that leads to structural and functional im-pairments and reduced quality of life, with heterogeneous manifestations. The origin and possible role of extracellular vesicles represented by exosomes (EVexo) in the pathogenesis of AS were examined in this study. Materials and Methods: Extracellular vesicles (EVs) were isolated from serum from ten AS patients and ten healthy controls through Izon qEV2/35 nm columns. After assessing the isolate purity by bicinchoninic acid assay (BCA) and Enzyme-Linked ImmunoSorbent Assay (ELISA), the relationship between EVexo concentration and AS was tested by the BCA method. The EVexo surface markers were analyzed by flow cytometry (FC) to verify EVexo presence and reveal its origin. Results: In FC analysis, CD86+TSG101+ and CD3+TSG101+ exosome percentages of AS group were significantly higher than the control group (p

Published
2023

5. Biologic therapy carries a very low risk of reactivation in hepatitis b surface antigen-negative phase of hepatitis b

Author

ALİBAZ ÖNER, FATMA and Ergenç İ., Kani H. T. , Karabacak M., Cömert Özer E., Mehdiyev S., Jafarov F., Abacar K. Y. , Kutluğ Ağaçkıran S., Sevik G., Aslan R., et al.

Subjects
reactivation, Anti-HBc IgG, biologic agents, anti-TNF, hepatitis B
Abstract

Background: The risk of hepatitis B reactivation in hepatitis B surface antigen-negative phase of hepatitis B virus-infected patients exposed to biologic agents is not clear. We aimed to investigate the reactivation rate in hepatitis B surface antigen-negative phase of hepatitis B virus-infected patients after biologic therapy. Methods: Patients followed at gastroenterology, rheumatology, and dermatology clinics with a diagnosis of immune-mediated inflammatory diseases were screened. Immune-mediated inflammatory diseases patients exposed to biologic agents with a negative hepatitis B surface antigen and positive hepatitis B core immunoglobulin G antibody were included in the study. Results: We screened 8266 immune-mediated inflammatory disease patients, and 2484 patients were identified as exposed to biologic agents. Two hundred twenty-one patients were included in the study. The mean age was 54.08 ± 11.69 years, and 115 (52.0%) patients were female. The median number of different biologic subtype use was 1 (range: 1-6). The mean biologic agent exposure time was 55 (range: 2-179) months. One hundred and fifty-two (68.8%) patients used a concomitant immunomodulatory agent, and 84 (38.0%) patients were exposed to corticosteroids during biologic use. No hepatitis B reactivation with a reverse seroconversion of hepatitis B surface antigen positivity was seen. Antiviral prophylaxis for hepatitis B was applied to 48 (21.7%) patients. Hepatitis B virus-DNA was screened in 56 (25.3%) patients prior to the biologic exposure. Two patients without antiviral prophylaxis had hepatitis B virus-DNA reactivation with a negative hepatitis B surface antigen during exposure to the biologic agent. Conclusion: We found 2 reactivations and no hepatitis B surface antigen seroconversion in our cohort. Antiviral prophylaxis for patients exposed to biologic agents may need to be discussed in more detail.

Published
2022

6. Potential protective effects of chronic aerobic exercise on cardiopulmonary health and vascular function in takayasu arteritis

Author

ALİBAZ ÖNER, FATMA, DİRESKENELİ, RAFİ HANER, and Yerli N. H. , Abacar K., Alibaz-Oner F., DİRESKENELİ R. H. , Kasimay O.

Subjects
Fizyoloji, Fizyoloji (tıbbi), Physiology, Temel Bilimler, Biochemistry (medical), Temel Tıp Bilimleri, Life Sciences, Life Sciences (LIFE), Biyokimya (tıbbi), Sağlık Bilimleri, Fundamental Medical Sciences, Biochemistry, BIOLOGY & BIOCHEMISTRY, Tıp, Human Physiology, Yaşam Bilimleri (LIFE), Biyokimya, Physiology (medical), Yaşam Bilimleri, Health Sciences, Biyoloji ve Biyokimya, Medicine, FİZYOLOJİ, Natural Sciences
Published
2022

7. Predictor factors in empowerment of patients with primary sjogren syndrome in the frame of value based health care

Author

MUMCU, GONCA and Mumcu G., Abacar K., Tatli I., Ture-Ozdemir F., Kitapci O. C. , Kitapci N. S. , Yay M., Karacayli U., Fortune F., Inanc N.

Subjects
Internal Diseases, RHEUMATOLOGY, Internal Medicine Sciences, Klinik Tıp, Dahili Tıp Bilimleri, CLINICAL MEDICINE, Sağlık Bilimleri, İmmünoloji ve Romatoloji, İç Hastalıkları, Clinical Medicine (MED), Tıp, Immunology and Rheumatology, Health Sciences, Medicine, Klinik Tıp (MED), Romatoloji, ROMATOLOJİ
Published
2022

8. The course and outcomes of covid-19 in patients with takayasu arteritis: case series of 15 patients from a tertiary single center

Author

DİRESKENELİ, RAFİ HANER, ALİBAZ ÖNER, FATMA, and Sevik G., Agackiran S. K. , Abacar K., Aliyeva A., DİRESKENELİ R. H. , Alibaz-Oner F.

Subjects
Internal Diseases, RHEUMATOLOGY, Internal Medicine Sciences, Klinik Tıp, Dahili Tıp Bilimleri, CLINICAL MEDICINE, Sağlık Bilimleri, İmmünoloji ve Romatoloji, İç Hastalıkları, Clinical Medicine (MED), Tıp, Immunology and Rheumatology, Health Sciences, Medicine, Klinik Tıp (MED), Romatoloji, ROMATOLOJİ
Published
2022

9. 18f-fluorodeoxyglucose (fdg) pet-ct imaging of salivary glands in primary sjogren's syndrome and its correlation with ultrasonographic scores and salivary flow rate compared to healthy controls

Author

ÖNEŞ, TUNÇ, MUMCU, GONCA, and Abacar K., Kissa T. N. , Oksuzoglu K., Ones T., Mumcu G., Bruyn G., Inanc N.

Subjects
Internal Diseases, RHEUMATOLOGY, Internal Medicine Sciences, Klinik Tıp, Dahili Tıp Bilimleri, CLINICAL MEDICINE, Sağlık Bilimleri, İmmünoloji ve Romatoloji, İç Hastalıkları, Clinical Medicine (MED), Tıp, Immunology and Rheumatology, Health Sciences, Medicine, Klinik Tıp (MED), Romatoloji, ROMATOLOJİ
Published
2022

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