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To understand the health needs and challenges experienced by the patient population served by a student-run free clinic in Jackson, Mississippi.A retrospective chart review was conducted on all patients who presented between 2017 and 2019. Data collected included age, race, sex, hometown, number of visits, chief complaint, lab utilization, blood pressure, and body mass index.The patient population was 73.3% African American and 55.5% female and came from 88 different towns across Mississippi. Most patients (54.1%) came only once. Nearly half (46.7%) of African American patients and 50.0% of White patients were obese. The top three chief complaints were health management (40.3%), STI/UTI (9.3%), and musculoskeletal (7.5%).The data indicate a need for the development of programs to improve patient access to care and resources: a community health outreach program, a social health services program, and further studies to determine the effectiveness of care provided.

50 Studies Every Ophthalmologist Should Know succinctly summarizes the most important and clinically relevant studies published in the mainstream ophthalmology literature in the past forty years. Emphasis has been placed on landmark studies, that changed thinking and practice in the field, rather than studies that are most frequently cited. Most are randomized controlled trials that have helped shape current ophthalmology practice guidelines. However, some important observational (cohort, case-control, and descriptive) studies are also included. The book is divided into seven sections, corresponding to anatomical segment or disease of the eye (cornea, cataract, glaucoma, vitreoretinal, macula, uveal tract, and orbit/eyelids/extraocular muscles/optic nerve). Each chapter finishes with an illustrative clinical case, and includes a reference to the relevant section of the practice guidelines of the American Academy of Ophthalmology. The book is not aimed solely at ophthalmologists, however. Every practicing physician, no matter his or her specialty, should be familiar with the relation of the eye to the rest of the human body, and with the use and value of the ophthalmoscope. Ophthalmology has a particular relevance to physicians working in primary care, internal medicine, neurology, neurosurgery, pediatrics, and emergency medicine.

Epidemiologic links between chronic hepatitis C and herpes simplex type-2 infection have been suggested; however, type-specific tests for HSV-2 infection have not been validated in patients with chronic hepatitis C infection. The Focus HerpeSelect(®) HSV-2 IgG (Cypress, California) assay and the Biokit HSV-2 rapid assay (Biokit USA, Lexington, MA) were performed on serum samples obtained from 84 veterans with chronic hepatitis C who demonstrated a previously positive HSV-2 serologic test in their medical records. Using the Biokit HSV-2 as the comparator assay, the positive predictive value, and specificity for the HerpeSelect(®) HSV-2 assay were 62.1% (95%CI: 49.3-73.8) and 41.9% (95%CI: 27.0-57.9), respectively. Increasing the HerpeSelect(®) HSV-2 index value defining a positive test result from1.1 to ≥2.89 increased the assay's specificity to 97.7% (95%CI: 87.7-99.6) and the positive predictive value to 94.1%(95%CI: 71.2-99.0). J. Med. Virol. 9999: 1-5, 2015. © 2015 Wiley Periodicals, Inc. In veterans with chronic hepatitis C infection, HerpeSelect(®) HSV-2 index values between 1.1 and 2.89 should be confirmed with an alternate test for HSV-2 infection.

High blood pressure (BP) is more prevalent and contributes to more severe manifestations of cardiovascular disease (CVD) in African Americans than in any other United States ethnic group. Several small African-ancestry (AA) BP genome-wide association studies (GWASs) have been published, but their findings have failed to replicate to date. We report on a large AA BP GWAS meta-analysis that includes 29,378 individuals from 19 discovery cohorts and subsequent replication in additional samples of AA (n = 10,386), European ancestry (EA) (n = 69,395), and East Asian ancestry (n = 19,601). Five loci (EVX1-HOXA, ULK4, RSPO3, PLEKHG1, and SOX6) reached genome-wide significance (p < 1.0 × 10(-8)) for either systolic or diastolic BP in a transethnic meta-analysis after correction for multiple testing. Three of these BP loci (EVX1-HOXA, RSPO3, and PLEKHG1) lack previous associations with BP. We also identified one independent signal in a known BP locus (SOX6) and provide evidence for fine mapping in four additional validated BP loci. We also demonstrate that validated EA BP GWAS loci, considered jointly, show significant effects in AA samples. Consequently, these findings suggest that BP loci might have universal effects across studied populations, demonstrating that multiethnic samples are an essential component in identifying, fine mapping, and understanding their trait variability.

To develop alternative estimates of the excess mortality attributable to diabetes in Mississippi.For each age/sex group, the total (all cause) mortality rate in the population was partitioned into the mortality rates for diabetics (M1) and non-diabetics (M0), using age- and sex-specific mortality rate ratios for diabetics from the Verona Diabetes Study. M1 and M0 were used, respectively, to calculate the predicted number of deaths and the 'usual' number of deaths (the number expected if diabetics had the same mortality rates as non-diabetics) in diabetics. The difference between predicted and 'usual' deaths is the number of excess deaths in diabetics--that is, deaths attributable specifically to diabetes. This was compared to the number of deaths in which diabetes was registered on death certificates as an underlying and/or contributory cause.In Mississippi in 1998-2000, 2,322 male and 3,436 female deaths in diabetics were calculated to be excess. These numbers are approximately three times the numbers of deaths in which diabetes was registered on the death certificate as the underlying cause of death. The excess numbers of deaths are much closer to the total numbers of deaths due to diabetes (that is, where diabetes is listed as either an underlying or a contributory cause of death).When reporting diabetes mortality numbers, public health agencies should consider reporting total registered diabetes deaths, not just registered underlying deaths. Better education of providers and others to increase the awareness of the importance of listing diabetes on the death certificate would help to increase concern and make diabetes a priority for public health action. Persons with diabetes have higher mortality rates and excess premature mortality, and diabetes ranks consistently among the leading causes of death in Mississippi and the U.S. Yet it has long been known that mortality attributable to diabetes is underestimated. Cause-of-death statistics are unreliable due to underreporting of diabetes on death certificates, and estimates based on attributable risk calculations do not take into account competing risks for mortality. In view of the public health importance of diabetes, it would be useful to develop alternative estimates of the burden of excess mortality attributable to it. In this paper I estimate the excess mortality attributable to diabetes for the diabetic population of Mississippi using epidemiologic data on the prevalence of diabetes and the relative risk of mortality among persons with diabetes.