333 results on '"Ali S. Raja"'
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2. Temporal Arteritis
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Ali S. Raja and Fernanda Bellolio
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- 2023
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3. Chest Pain
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Christopher R. Carpenter and Ali S. Raja
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- 2023
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4. Occult Scaphoid Fractures
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Christopher R. Carpenter and Ali S. Raja
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- 2023
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5. Occult Hip Fracture
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Ali S. Raja and Jesse M. Pines
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- 2023
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6. Intraocular Pressure
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Ali S. Raja and Jesse M. Pines
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- 2023
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7. Skin and Soft Tissue Infections
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Ali S. Raja and Fernanda Bellolio
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- 2023
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8. Penetrating Abdominal Trauma
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Jesse M. Pines and Ali S. Raja
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- 2023
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9. Deep Vein Thrombosis
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Ali S. Raja and Jesse M. Pines
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- 2023
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10. Urinary Tract Infection
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Jonathan Sheele and Ali S. Raja
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- 2023
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11. Penetrating Trauma to the Extremities and Vascular Injuries
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Christopher R. Carpenter and Ali S. Raja
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- 2023
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12. Aortic Emergencies
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Ali S. Raja and Jesse M. Pines
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- 2023
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13. Pulmonary Embolism
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Lauren Westafer and Ali S. Raja
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- 2023
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14. Intravascular Volume Status
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Ali S. Raja and Christopher R. Carpenter
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- 2023
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15. Evidence‐Based Medicine
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Ali S. Raja and Jesse M. Pines
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- 2023
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16. Influenza
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Ali S. Raja and Christopher R. Carpenter
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- 2023
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17. Blunt Soft Tissue Neck Trauma
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Ali S. Raja and Jesse M. Pines
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- 2023
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18. Acute Low Back Pain
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Jesse M. Pines and Ali S. Raja
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- 2023
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19. CT utilization in evaluation of skin and soft tissue extremity infections in the ED: Retrospective cohort study
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Andy H. Lee, Yosef Berlyand, Sayon Dutta, Marc D. Succi, Jonathan D. Sonis, Brian J. Yun, Ali S. Raja, Anand Prabhakar, and Joshua J. Baugh
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Emergency Medicine ,General Medicine - Abstract
Skin and soft tissue infections (SSTI) are commonly diagnosed in the emergency department (ED). While most SSTI are diagnosed with patient history and physical exam alone, ED clinicians may order CT imaging when they suspect more serious or complicated infections. Patients who inject drugs are thought to be at higher risk for complications from SSTI and may undergo CT imaging more frequently. The objective of this study is to characterize CT utilization when evaluating for SSTI in ED patients particularly in patients with intravenous drug use (IVDU), the frequency of significant and actionable findings from CT imaging, and its impact on subsequent management and ED operations.We performed a retrospective analysis of encounters involving a diagnosis of SSTI in seven EDs across an integrated health system between October 2019 and October 2021. Descriptive statistics were used to assess overall trends, compare CT utilization frequencies, actionable imaging findings, and surgical intervention between patients who inject drugs and those who do not. Multivariable logistic regression was used to analyze patient factors associated with higher likelihood of CT imaging.There were 4833 ED encounters with an ICD-10 diagnosis of SSTI during the study period, of which 6% involved a documented history of IVDU and 30% resulted in admission. 7% (315/4833) of patients received CT imaging, and 22% (70/315) of CTs demonstrated evidence of possible deep space or necrotizing infections. Patients with history of IVDU were more likely than patients without IVDU to receive a CT scan (18% vs 6%), have a CT scan with findings suspicious for deep-space or necrotizing infection (4% vs 1%), and undergo surgical drainage in the operating room within 48 h of arrival (5% vs 2%). Male sex, abnormal vital signs, and history of IVDU were each associated with higher likelihood of CT utilization. Encounters involving CT scans had longer median times to ED disposition than those without CT scans, regardless of whether these encounters resulted in admission (9.0 vs 5.5 h), ED observation (5.5 vs 4.1 h), or discharge (6.8 vs 2.9 h).ED clinicians ordered CT scans in 7% of encounters when evaluating for SSTI, most frequently in patients with abnormal vital signs or a history of IV drug use. Patients with a history of IVDU had higher rates of CT findings suspicious for deep space infections or necrotizing infections and higher rates of incision and drainage procedures in the OR. While CT scans significantly extended time spent in the ED for patients, this appeared justified by the high rate of actionable findings found on imaging, particularly for patients with a history of IVDU.
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- 2023
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20. Trends in female first-author abstracts at the Society for Academic Emergency Medicine Annual Meeting, 1990–2020
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Rebecca E. Cash, Christopher L. Bennett, Krislyn M. Boggs, Margaret E. Samuels-Kalow, Monica Saxena, Melissa Pasao, Ali S. Raja, and Carlos A. Camargo
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Male ,Cross-Sectional Studies ,Research Design ,Emergency Medicine ,Humans ,Female ,General Medicine ,Minority Groups - Abstract
To describe first author gender differences and characteristics in 1) Society for Academic Emergency Medicine (SAEM) Annual Meeting abstracts and 2) resulting manuscript publications.We performed cross-sectional evaluation of SAEM abstracts from 1990, 1995, 2000, 2005, 2010, 2015, and 2020, compiling and reviewing a random sample of 100 abstracts for each year (total n = 700 abstracts). We documented abstract characteristics, including first author gender, and used the 2020 SAEM scoring rubric. We then searched PubMed to identify manuscript publications resulting from abstracts from 1990 to 2015 (n = 600). Finally, among abstracts that resulted in manuscript publication, we identified first and last author gender on both the abstracts and the resulting publication.Overall, 29% (202/695; n = 5 missing gender) of abstracts had female first authors. Female first authors increased over time (e.g., 17% in 1990 to 35% in 2020). Abstract quality scores were similar (both median [interquartile range] of 11 ([9-12]). Overall, 42% (n = 254/600) of abstracts resulted in a manuscript publication, 39% (n = 65/202) with female and 44% (n = 189/493) with male first authors (p = 0.26). The median time (IQR) from abstract to manuscript publication was longer for abstracts with female first authors vs. those with male first authors (2 [1-3] years and 1 [1, 2] years, p0.02); 77% and 78% of publications resulting from abstracts with female and male first authors, respectively, had the same first author. Female first author abstracts more often converted to a male first author manuscript publication (18%, n = 12/65) compared to male first author abstracts converting to female first author publications (7%, n = 14/189).A minority of SAEM abstracts, and manuscript publications resulting from them, had female first authors. Abstracts with female first authors took longer to achieve manuscript publication, and almost a fifth of female first author abstracts resulted in male first author manuscript publication.
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- 2023
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21. Level-loading a health system by transferring emergency department patients to a community hospital: Prospective cohort study
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Andy H. Lee, Yosef Berlyand, Peter F. Dunn, Eric Goralnick, Lien H. Le, Ali S. Raja, Joshua J. Baugh, Stephanie Cooper, and Brian J. Yun
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Patient Admission ,Emergency Medicine ,Humans ,Hospitals, Community ,Prospective Studies ,General Medicine ,Length of Stay ,Emergency Service, Hospital ,Retrospective Studies - Abstract
Emergency department boarding and crowding lead to worse patient outcomes and patient satisfaction.We describe the implementation of a program to transfer patients requiring medical admission from an academic emergency department to a community hospital's medical floor and analyze its effects on patient outcomes.A prospective cohort study was performed. Data was collected on patient flow through the transfer program. Patient characteristics, boarding time in the emergency department, and hospital-based outcome measures were compared between patients in the transfer program who were successfully transferred to the community hospital and patients who were admitted to the academic medical center.79 patients were successfully transferred to the community hospital between November 23, 2020 and August 5, 2021, resulting in 279 bed days in the community hospital. Successfully transferred patients experienced a statistically shorter ED boarding time (5.7 vs. 10.9 h, p0.0001), ED length of stay (10.5 vs 16.1 h, p0.0001), and hospital length of stay (3.5 vs 5.7 days, p0.0001) compared to patients initially referred to the transfer program who were admitted to the academic medical center. There were no reported adverse events during transfer, upgrades to the ICU within 24 h of admission, or inpatient deaths for patients who were transferred.We implemented an academic emergency department to partner community hospital transfer program that safely level-loads medical patients in a healthcare system.
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- 2022
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22. Changes in scientific characteristics of abstracts accepted to the Society for Academic Emergency Medicine Annual Meeting, 1990–2020
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Carlos A. Camargo, Krislyn M. Boggs, Rebecca E. Cash, Vishal P. Doshi, Henry H. Isaacson, Kohei Hasegawa, and Ali S. Raja
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Cohort Studies ,Cross-Sectional Studies ,Abstracting and Indexing ,Emergency Medicine ,Humans ,Multicenter Studies as Topic ,General Medicine ,Congresses as Topic ,Societies, Medical - Abstract
Since its founding in 1989, the Society for Academic Emergency Medicine (SAEM) has accepted thousands of abstracts for presentation at its annual meeting. We reviewed abstracts to characterize temporal changes in study design, abstract topics, quality scores, and proportion of abstracts published as manuscripts.In this serial cross-sectional study, we compiled accepted SAEM abstracts at 5-year intervals (1990, 1995, 2000, 2005, 2010, 2015, 2020) and then randomly selected 100 abstracts from each year for review by two investigators. We documented each abstract's study design, sample size, and whether it was a single-center or multicenter study. We assigned each abstract to the most appropriate topic category. Applying SAEM's abstract scoring system from 2020, we calculated the mean overall quality score per year. Finally, we searched PubMed to determine if abstracts from 1990-2015 meetings were published as manuscripts.The number of accepted abstracts increased from 180 in 1990 to 879 in 2020 (+388%). The most common study design changed from laboratory study in 1990 (22%) to cohort study in 2020 (44%; p 0.001). The median study sample size increased over time, from 105 (interquartile range [IQR] 25-389) in 1990 to 544 (IQR 102-2067) in 2020 (p 0.001). Multicenter studies have become more common (19% in 1990 vs. 40% in 2020; p = 0.001). The most common topic categories also changed from cardiology/pulmonary/airway (40%) and orthopedic/trauma/burn (17%) in 1990 to health services research/health policy/operations (25%) and cardiology/pulmonary/airway (22%) in 2020. There was a 20% increase in overall quality scores (p 0.001). Between 37% and 49% of the abstracts reviewed from each year were later published as manuscripts, with no significant change over time (p = 0.33).Over the past 30 years, there have been significant changes to the study designs, topics, and quality scores of SAEM meeting abstracts. However, conversion of abstracts to published manuscripts remains a challenge.
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- 2022
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23. Changes in application of the Society for Academic Emergency Medicine's abstract scoring criteria, 2020 versus 2021
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Krislyn M. Boggs, Rebecca E. Cash, Dorsey Glew, Piroz Bahar, Kohei Hasegawa, Ali S. Raja, and Carlos A. Camargo
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Emergency Medicine ,General Medicine - Published
- 2023
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24. Evaluation of a COVID-19 emergency department observation protocol
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Yosef Berlyand, Joshua J. Baugh, Andy Hung-Yi Lee, Stephen Dorner, Susan R. Wilcox, Ali S. Raja, and Brian J. Yun
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Clinical Observation Units ,SARS-CoV-2 ,Emergency Medicine ,COVID-19 ,Humans ,Observation ,General Medicine ,Emergency Service, Hospital ,Retrospective Studies - Abstract
Caring for patients with COVID-19 has resulted in a considerable strain on hospital capacity. One strategy to mitigate crowding is the use of ED-based observation units to care for patients who may have otherwise required hospitalization. We sought to create a COVID-19 Observation Protocol for our ED Observation Unit (EDOU) for patients with mild to moderate COVID-19 to allow emergency physicians (EP) to gather more data for or against admission and intervene in a timely manner to prevent clinical deterioration.This was a retrospective cohort study which included all patients who were positive for SARS-CoV-2 at the time of EDOU placement for the primary purpose of monitoring COVID-19 disease. Our institution updated the ED Observation protocol partway into the study period. Descriptive statistics were used to characterize demographics. We assessed for differences in demographics, clinical characteristics, and outcomes between admitted and discharged patients. Multivariate logistic regression models were used to assess whether meeting criteria for the ED observation protocols predicted disposition.During the time period studied, 120 patients positive for SARS-CoV-2 were placed in the EDOU for the primary purpose of monitoring COVID-19 disease. The admission rate for patients in the EDOU during the study period was 35%. When limited to patients who met criteria for version 1 or version 2 of the protocol, this dropped to 21% and 25% respectively. Adherence to the observation protocol was 62% and 60% during the time of version 1 and version 2 implementation, respectively. Using a multivariate logistic regression, meeting criteria for either version 1 (OR = 3.17, 95% CI 1.34-7.53, p0.01) or version 2 (OR = 3.18, 95% CI 1.39-7.30, p0.01) of the protocol resulted in a higher likelihood of discharge. There was no difference in EDOU LOS between admitted and discharged patients.An ED observation protocol can be successfully created and implemented for COVID-19 which allows the EP to determine which patients warrant hospitalization. Meeting protocol criteria results in an acceptable admission rate.
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- 2022
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25. Towards a more efficient healthcare system: Opportunities and challenges caused by hospital closures amid the COVID-19 pandemic
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Soroush Saghafian, Lina D. Song, and Ali S. Raja
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Elective Surgical Procedures ,Health Personnel ,General Health Professions ,COVID-19 ,Humans ,Medicine (miscellaneous) ,Pandemics ,United States ,Health Facility Closure - Abstract
A substantial number of United States (U.S.) hospitals have closed in recent years. The trend of closures has accelerated during the COVID-19 pandemic, as hospitals have experienced financial hardship from reduced patient volume and elective surgery cases, as well as the thin financial margins for treating patients with COVID-19. This trend of hospital closures is concerning for patients, healthcare providers, and policymakers. In this current opinion piece, we first describe the challenges caused by hospital closures and discuss what policymakers should know based on the existing research. We then discuss unique opportunities for researchers to inform policymakers by conducting careful studies that can shed light on different implications, trade-offs, and consequences of various strategies that can be followed.
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- 2022
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26. Increased per-patient imaging utilization in an emergency department setting during COVID-19
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Michael S. Gee, James A. Brink, Marc D. Succi, Sanjay Saini, Raymond W. Liu, Ali S. Raja, Ken Chang, Thomas J. An, David A. Rosman, and Michael H. Lev
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2019-20 coronavirus outbreak ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,Revenue ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Primary outcome ,Secondary analysis ,Internal medicine ,Operations ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,In patient ,Retrospective Studies ,business.industry ,Relative value unit ,COVID-19 ,Retrospective cohort study ,Emergency department ,030220 oncology & carcinogenesis ,Musculoskeletal and Emergency Imaging ,Emergency Service, Hospital ,business - Abstract
Introduction COVID-19 has resulted in decreases in absolute imaging volumes, however imaging utilization on a per-patient basis has not been reported. Here we compare per-patient imaging utilization, characterized by imaging studies and work relative value units (wRVUs), in an emergency department (ED) during a COVID-19 surge to the same period in 2019. Methods This retrospective study included patients presenting to the ED from April 1–May 1, 2020 and 2019. Patients were stratified into three primary subgroups: all patients (n = 9580, n = 5686), patients presenting with respiratory complaints (n = 1373, n = 2193), and patients presenting without respiratory complaints (n = 8207, n = 3493). The primary outcome was imaging studies/patient and wRVU/patient. Secondary analysis was by disposition and COVID status. Comparisons were via the Wilcoxon rank-sum or Chi-squared tests. Results The total patients, imaging exams, and wRVUs during the 2020 and 2019 periods were 5686 and 9580 (−41%), 6624 and 8765 (−24%), and 4988 and 7818 (−36%), respectively, and the percentage patients receiving any imaging was 67% and 51%, respectively (p
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- 2021
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27. Prevalence of imaging findings of acute pancreatitis in emergency department patients with elevated serum lipase
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Aaron D. Sodickson, Peter A. Banks, Ali S. Raja, David X. Jin, Lailah R. Cochon, Daniel I. Glazer, and Ramin Khorasani
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Male ,medicine.medical_specialty ,Population ,Gastroenterology ,Elevated serum ,Internal medicine ,Prevalence ,medicine ,Humans ,Serum lipase ,Lipase ,education ,Retrospective Studies ,education.field_of_study ,biology ,business.industry ,Retrospective cohort study ,General Medicine ,Emergency department ,Middle Aged ,medicine.disease ,Magnetic Resonance Imaging ,Pancreatitis ,Emergency Medicine ,biology.protein ,Population study ,Acute pancreatitis ,Female ,Emergency Service, Hospital ,Tomography, X-Ray Computed ,business ,Biomarkers - Abstract
To assess the association of imaging features of acute pancreatitis (AP) with the magnitude of lipase elevation in Emergency Department (ED) patients.This Institutional Review Board-approved retrospective study included 509 consecutive patients presenting from 9/1/13-8/31/15 to a large academic ED with serum lipase levels ≥3× the upper limit of normal (ULN) (≥180 U/L). Patients were excluded if they did not have imaging (n = 131) or had a history of trauma, abdominal metastases, altered mental status, or transfer from an outside hospital (n = 190); the final study population was 188 patients. Imaging exams were retrospectively evaluated, and a consensus opinion of two subspecialty-trained abdominal radiologists was used to diagnose AP. Primary outcome was presence of imaging features of AP stratified by lipase level (≥3×-10× ULN and10× ULN). Secondary outcome was rate of discordant consensus evaluation compared to original radiologist's report.25.0% of patients (47/188) had imaging features of AP. When lipase was10× ULN (n = 94), patients were more likely to have imaging features of AP (34%) vs. those with mild elevation (16%) (p = 0.0042). There was moderately strong correlation between lipase level and presence of imaging features of AP (r = 0.48, p0.0001). Consensus review of CT and MRI images was discordant with the original report in 14.9% (28/188) of cases.Prevalence of imaging signs of AP in an ED population with lipase ≥3× ULN undergoing imaging is low. However, the probability of imaging features of AP increases as lipase value increases.
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- 2021
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28. A systematic review and meta-analysis of clinical signs, symptoms, and imaging findings in patients with suspected renal colic
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Philipp Dahm, Alex Koziarz, Charles J. Gerardo, Daniel K. Nishijima, Jae Hung Jung, Simranjeet Benipal, and Ali S. Raja
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physical examination findings ,screening and diagnosis ,Kidney Disease ,evidence-based clinical practice ,7.3 Management and decision making ,meta-analysis ,Detection ,renal colic ,systematic review ,meta‐analysis ,General Earth and Planetary Sciences ,Biomedical Imaging ,diagnostic accuracy ,Management of diseases and conditions ,evidence‐based clinical practice ,General Environmental Science ,4.2 Evaluation of markers and technologies - Abstract
Study objectiveThe objective of this study was to conduct a systematic review and meta-analysis of the diagnostic accuracy of the clinical signs, symptoms, laboratory investigations, and imaging modalities commonly used in patients with clinically suspected renal colic.MethodsWe conducted this systematic reviewand meta-analysisaccording to an a priori, registered protocol (PROSPERO CRD42017055153). A literature search was performed using MEDLINE and EMBASE from inception to July 2, 2020. We assessed the risk of bias using Quality Assessment of Diagnostic Accuracy Studies-2, calculated likelihood ratios (LRs), and applied a random-effects model for meta-analysis.ResultsAmong 7641 references screened, 76 were included in the systematic review and 53 were included in the meta-analyis. The overall pooled prevalence for ureteral stones was 63% (95% confidence interval [CI], 58%-67%). No individual demographic feature, symptom, or sign when present had an LR+ ≥2.0 for identifying ureterolithiasis. A (Sex, Timing and Origin of pain, race, presence or absence of Nausea, and Erythrocytes) STONE score ≥10 increased (sensitivity 0.49, specificity 0.91, LR 5.3 [95% CI, 4.1-6.7]) and a STONE score 
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- 2022
29. Continuation of outpatient buprenorphine therapy after dispensing Buprenorphine-Naloxone from the emergency department
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Alister Martin, James R. Krenz, Ali S. Raja, Bryan D. Hayes, Sarah E. Wakeman, Jennifer L. Koehl, and Benjamin A. White
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medicine.medical_specialty ,Adolescent ,business.industry ,Narcotic Antagonists ,Opioid use disorder ,General Medicine ,Emergency department ,Opioid-Related Disorders ,Toxicology ,medicine.disease ,Buprenorphine ,Substance abuse ,Outpatients ,Emergency medicine ,Buprenorphine/naloxone ,medicine ,Humans ,Buprenorphine, Naloxone Drug Combination ,Emergency Service, Hospital ,business ,Retrospective Studies ,medicine.drug - Abstract
Patients with opioid use disorder (OUD) are frequently seen in the ED for opioid-related reasons, which creates an opportunity for ED providers to discuss medications for OUD with their patients. Buprenorphine is a partial mu-opioid agonist that is FDA approved to treat OUD and may be initiated in the ED. Traditionally, buprenorphine therapy was initiated under healthcare provider observation; however, other strategies such as at-home induction have also emerged.This was a retrospective descriptive analysis of patients aged 18 years or older who received a take-home supply of buprenorphine-naloxone from an urban, academic ED between March 2018 and March 2020. The primary outcome was the proportion of patients who filled a prescription for buprenorphine at three months after index ED visit. The proportion of patients that filled a prescription for buprenorphine at six months was also evaluated. The primary safety endpoint was the proportion of patients with return ED visit within six months related to opioid overdose.There were 242 patient records reviewed with 155 patients included in final analysis. Seventy (45.2%) patients filled buprenorphine prescriptions at three months, with 64 (41.3%) who filled buprenorphine prescriptions at six months. Seventeen (11%) patients had a return ED visit related to opioid overdose within six months.Dispensing buprenorphine take-home kits from the ED resulted in continuation of outpatient buprenorphine in almost 50% of patients. Further studies are warranted to define the role of ED-dispensed buprenorphine.
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- 2021
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30. Impact of iodinated contrast allergies on emergency department operations
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Yosef Berlyand, John Anthony Fraga, Marc D. Succi, Brian J. Yun, Andy Hung-Yi Lee, Joshua J. Baugh, David Whitehead, Ali S. Raja, and Anand M. Prabhakar
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Drug Hypersensitivity ,Emergency Medicine ,Humans ,Contrast Media ,General Medicine ,Tomography, X-Ray Computed ,Emergency Service, Hospital ,Retrospective Studies - Abstract
Adverse reactions to intravenous (IV) iodinated contrast media are classified by the American College of Radiology (ACR) Manual on Contrast Media as either allergic-like (ALR) or physiologic (PR). Premedication may be beneficial for patients who have prior documented mild or moderate ALR. We sought to perform a retrospective analysis of patients who received computed tomography (CT) imaging in our emergency department (ED) to establish whether listing of an iodinated contrast media allergy results in a delay in care, increases the use of non-contrast studies, and to quantify the incidence of listing iodinated contrast allergies which do not necessitate premedication.We performed a retrospective analysis of CT scans performed in our academic medical center ED during a 6-month period. There were 12,737 unique patients of whom 454 patients had a listed iodinated contrast allergy. Of these, 106 received IV contrast and were categorized as to whether premedication was necessary. Descriptive statistics were used to evaluate patient demographics, clinical characteristics, and operational outcomes. A multivariate linear regression model was used to predict time from order to start (OTS time) of CT imaging while controlling for co-variates.Non-allergic patients underwent contrast-enhanced CT imaging at a significantly higher rate than allergic patients (45.9% vs. 23.3%, p0.01). The OTS time for allergic patients who underwent contrast-enhanced CT imaging was 360 min and significantly longer than the OTS time for non-allergic patients who underwent contrast-enhanced CT imaging (118 min, p0.001). Of the 106 allergic patients who underwent contrast-enhanced CT imaging, 27 (25.5%) did not meet ACR criteria for necessitating premedication. The average OTS time for these 27 patients was 296 min, significantly longer than the OTS for non-allergic patients (118 min, p0.01) and did not differ from the OTS time for the 79 patients who did meet premedication criteria (382 min, p = 0.23). A multivariate linear regression showed that OTS time was significantly longer if a contrast allergy was present (p0.001).A chart-documented iodinated contrast allergy resulted in a significant increase in time to obtain a contrast-enhanced CT study. This delay persisted among patients who did not meet ACR criteria for premedication. Appropriately deferring premedication could potentially reduce the ED length-of-stay by over 4 h for these patients.
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- 2022
31. Emergency Department-initiated Buprenorphine and Referral to Follow-up Addiction Care: A Program Description
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Ali S. Raja, Sarah E. Wakeman, Dawn Williamson, Susan Regan, Elizabeth Powell, Sayon Dutta, Laura Kehoe, Sydney Howard, Benjamin A. White, Bryan D. Hayes, and Alister Martin
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Adult ,Male ,Program evaluation ,medicine.medical_specialty ,Referral ,Rate ratio ,Humans ,Medicine ,Pharmacology (medical) ,Program Development ,Medical prescription ,Referral and Consultation ,business.industry ,Opioid use disorder ,Emergency department ,Healthcare Effectiveness Data and Information Set ,Opioid-Related Disorders ,medicine.disease ,Buprenorphine ,Psychiatry and Mental health ,Emergency medicine ,Emergency Service, Hospital ,business ,Follow-Up Studies ,medicine.drug - Abstract
Introduction Emergency department (ED) initiated opioid use disorder (OUD) care is effective; however, real-world predictors of patient engagement are lacking. Objective This program evaluation examined predictors of ED-based OUD treatment and subsequent engagement. Method Program evaluation in Boston, MA. Adult patients who met criteria for OUD during an ED visit in 2019 were included. Patients were included if a diagnosis of OUD or opioid-related overdose was associated with the ED visit or if they met previously validated criteria for OUD within the previous 12 months. We assessed predictors of ED-OUD treatment receipt and subsequent engagement, using Healthcare Effectiveness Data and Information Set definition of initial encounter within 14 days of discharge and either 2 subsequent encounters or a subsequent buprenorphine prescription within 34 days of the initial encounter. We used generalized estimating equations for panel data. Results During 2019, 1946 patients met criteria for OUD. Referrals to Bridge Clinic were made for 207 (11%), buprenorphine initiated for 106 (5%), and home induction buprenorphine kits given to 56 (3%). Following ED discharge, 237 patients (12%) had a visit within 14 days, 122 (6%) had ≥2 additional visits, and 207 (11%) received a subsequent buprenorphine prescription. Young, White, male patients were most likely to receive ED-OUD care. Patients who received ED-OUD care were more likely to have subsequent treatment engagement (adjusted rate ratio: 2.30, 95% confidence intervals: 1.62-3.27). Referrals were made less often than predicted for Black (-49%) or Hispanic/Latinx (-25%) patients. Conclusions Initiating treatment for OUD in the ED was associated with increased engagement in outpatient addiction care.
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- 2021
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32. A Case–control Study of Major Genetic Predisposition Risk Alleles in Developing DDD in the Northeast US Population: Effects of Gene–gene Interactions
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Bingxue K. Zhai, Ronilda Lacson, Vladimir I. Valtchinov, Hiroro Hatabu, Tomoyuki Hida, Ali S. Raja, and Ramin Khorasani
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Male ,Dichlorodiphenyldichloroethane ,medicine.medical_specialty ,Population ,Single-nucleotide polymorphism ,Polymorphism, Single Nucleotide ,Degenerative disc disease ,Polymorphism (computer science) ,Internal medicine ,Humans ,Medicine ,SNP ,Genetic Predisposition to Disease ,Orthopedics and Sports Medicine ,education ,Alleles ,education.field_of_study ,business.industry ,Case-control study ,Odds ratio ,Middle Aged ,equipment and supplies ,medicine.disease ,Case-Control Studies ,Cohort ,Neurology (clinical) ,business - Abstract
STUDY DESIGN A case-control study of risk alleles for degenerative disc disease (DDD) using magnetic resonance (MR) imaging for phenotyping. OBJECTIVE We aim to provide the first statistically adequately powered study of the relationship between the presence of common risk alleles and occurrence of DDD in Eastern US population. SUMMARY OF BACKGROUND DATA Many genetic predisposing factors have been identified in elevating the risk of DDD, including common variants in VDR, COL1A1, AGC1, COL9A2/3 genes. METHODS We utilized the Mass General Brigham (MGB) Biobank in which subjects' Medical Record is linked with genotyped data from single-nucleotide polymorphism (SNP) arrays. Subjects with lumbosacral spine MR imaging studies were used to construct the Cases cohort; the Biobank's Controls cohort was used as the Control cohort. Odds ratios (OR) and False-discovery-rate (FDR) q values from multiple-hypotheses-testing corrections were used to assess the likelihood of DDD given occurrence of the listed DDD risk alleles. RESULTS Four-hundred-fourteen subjects (mean age = 64, range = 27 to 94) were Cases and 925 Controls (mean age = 46, range = 21-61). A systematic search has identified 25 SNPs in 18 genes in the SNP arrays. At univariate level, rs1544410 in VDR was significantly associated with DDD for male subjects (odds ratio [OR] = 0.594, P = 0.011). After adjustment for all significant variants and demographics, three predictor variables had a significant association with the outcome, age (OR = 1.130, q
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- 2021
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33. Help Us Help You: Engaging Emergency Physicians to Identify Organizational Strategies to Reduce Burnout
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Ali S. Raja, Joshua J Baugh, and James K. Takayesu
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Educational Advances ,Quality management ,education ,Psychological intervention ,Burnout ,Job Satisfaction ,Documentation ,Intervention (counseling) ,Physicians ,Surveys and Questionnaires ,Health care ,Medicine ,Humans ,Prospective Studies ,Workplace ,Burnout, Professional ,Medical education ,Academic Medical Centers ,business.industry ,RC86-88.9 ,Medical emergencies. Critical care. Intensive care. First aid ,General Medicine ,Emergency department ,Work Engagement ,Quality Improvement ,Action plan ,Emergency Medicine ,Provider Workforce ,business ,psychological phenomena and processes - Abstract
Introduction: Burnout is a major threat to patient care quality and physician career longevity in emergency medicine. We sought to develop and implement a quality improvement process to engage emergency department (ED) faculty in identifying sources of burnout and generating interventions targeted at improving the work environment. Methods: In this prospective interventional study conducted at a large, urban, academic medical center, we surveyed a 60-person faculty group using the Professional Fulfilment Index (PFI), as well as burnout-relevant questions from the American Medical Association’s Mini-Z survey and the Maslach-Leiter framework for organizational burnout, in order to identify organizational sources of burnout. We assessed the relationship between burnout scores and responses to the Maslach-Leiter framework using univariate regression analysis. In a two-hour facilitated session, we shared survey results and led the group in a process using the six Maslach-Leiter domains to develop a rank-ordered list of interventions to reduce burnout in each domain. Results: In total, 47 of 60 faculty (78.3%) completed the survey and 45 faculty (75%) attended the discussion session. Of the 47 survey respondents, 14 (30%) met criteria for moderate to severe burnout. The respondents’ answers to the Maslach-Leiter organizational burnout domain questions were significantly correlated with their burnout scores (P
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- 2021
34. Exacerbation of Physical Intimate Partner Violence during COVID-19 Pandemic
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Bharti Khurana, Steven E. Seltzer, Mitchel B. Harris, Giles W. Boland, Rahul Gujrathi, Meghan L McDonald, Marta Chadwick Balcom, Dennis P. Orgill, Kathryn M. Rexrode, Babina Gosangi, Camden P. Bay, Ali S. Raja, Hye Sun Park, and Richard Thomas
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Adult ,Male ,medicine.medical_specialty ,education ,Intimate Partner Violence ,Poison control ,Occupational safety and health ,030218 nuclear medicine & medical imaging ,Young Adult ,03 medical and health sciences ,Injury Severity Score ,0302 clinical medicine ,Injury prevention ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Young adult ,Retrospective Studies ,Original Research ,Emergency Radiology ,business.industry ,Incidence ,Public health ,Incidence (epidemiology) ,COVID-19 ,social sciences ,Middle Aged ,United States ,Physical abuse ,030220 oncology & carcinogenesis ,Wounds and Injuries ,Domestic violence ,Female ,business ,Demography - Abstract
Background Intimate partner violence (IPV) is a global social and public health problem, but published literature regarding the exacerbation of physical IPV during the coronavirus disease 2019 (COVID-19) pandemic is lacking. Purpose To assess the incidence, patterns, and severity of injuries in IPV victims during the COVID-19 pandemic in 2020 compared with the prior 3 years. Materials and Methods The demographics, clinical presentation, injuries, and radiologic findings of patients reporting physical abuse arising from IPV during the statewide COVID-19 pandemic between March 11 and May 3, 2020, were compared with data from the same period for the past 3 years. Pearson χ2 and Fisher exact tests were used for analysis. Results A total of 26 victims of physical IPV from 2020 (mean age, 37 years ± 13 [standard deviation]; 25 women) were evaluated and compared with 42 victims of physical IPV (mean age, 41 years ± 15; 40 women) from 2017 to 2019. Although the overall number of patients who reported IPV decreased during the pandemic, the incidence of physical IPV was 1.8 times greater (95% CI: 1.1, 3.0; P = .01). The total number of deep injuries was 28 during 2020 versus 16 from 2017 to 2019; the number of deep injuries per victim was 1.1 during 2020 compared with 0.4 from 2017 to 2019 (P < .001). The incidence of high-risk abuse defined by mechanism was two times greater in 2020 (95% CI: 1.2, 4.7; P = .01). Patients who experienced IPV during the COVID-19 pandemic were more likely to be White; 17 (65%) victims in 2020 were White compared with 11 (26%) in the prior years (P = .007). Conclusion There was a higher incidence and severity of physical intimate partner violence (IPV) during the coronavirus disease 2019 (COVID-19) pandemic compared with the prior 3 years. These results suggest that victims of IPV delayed reaching out to health care services until the late stages of the abuse cycle during the COVID-19 pandemic. © RSNA, 2020.
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- 2021
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35. Analysis of self-initiated visits for cervical trauma at urgent care centers and subsequent emergency department referral
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Azan Z. Virji, Abraham Z. Cheloff, Soham Ghoshal, Baily Nagle, Teddy Z. Guo, Michael H. Lev, Ali S. Raja, Michael S. Gee, and Marc D. Succi
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Humans ,Radiology, Nuclear Medicine and imaging ,Emergency Service, Hospital ,Ambulatory Care Facilities ,Referral and Consultation ,Retrospective Studies - Abstract
Following trauma involving the cervical spine (c-spine), patients often seek care at urgent care centers (UCCs) or emergency departments (EDs).The purpose was to assess whether UCCs could effectively image acute self-selected c-spine trauma without referral to the ED as well as to estimate costs differences between UCC and ED imaging assessment.This retrospective study identified patients receiving c-spine imaging at UCCs affiliated with a large academic hospital system from 5/1/-8/31/2021. Patients receiving c-spine X-rays with an indication of trauma following low acuity injury, at UCCs were compared to patients receiving any c-spine imaging in the main campus ED. Medical record numbers were cross-referenced to identify patients receiving imaging at both a UCC and ED within 24 h and within 7 days. Work relative value units (wRVUs) for each UCC and ED imaging type were calculated. For the hypothetical scenario of patients presenting to the ED in the absence of UCC, patients were assumed to receive c-spine computed tomography (CT) without contrast per "usually appropriate" designation by the American College of Radiology Appropriateness Criteria®.Among 143 self-selected, low acuity, patients who received c-spine X-rays at UCCs with an indication of trauma, one required referral to the ED within 24 h and two required referrals to the ED within 7 days. During the 4-month study period, 105.94 wRVUs ($3696.25) were saved by performing a c-spine X-ray in an UCC instead of a CT in the ED, extrapolated to 317.82 wRVUs ($11,088.74) per year. Using the average total costs of an UCC visit versus an ED visit, a total $145,976 was estimated to be saved during the study period or $437,928 per year.Offering access for patient-initiated visits at UCCs for low-acuity c-spine trauma may help reduce the need for an ED visit, reducing imaging and healthcare visit costs.Urgent Care Centers (UCCs) reduced the need for an Emergency Department (ED) referral visit in nearly 100% of self-selected, low acuity, patients with cervical trauma.
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- 2022
36. Utilization of a multidisciplinary emergency department sepsis huddle to reduce time to antibiotics and improve SEP-1 compliance
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Maria Vareschi, Elizabeth S. Temin, Michael R. Filbin, Bryan D. Hayes, Jonathan D. Sonis, Lauren Black, Kathryn A. Hibbert, Susan R. Wilcox, Cassie Kraus, Ali S. Raja, Theodore I. Benzer, Emily L. Aaronson, and Benjamin A. White
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Male ,medicine.medical_specialty ,medicine.drug_class ,Antibiotics ,Centers for Medicare and Medicaid Services, U.S ,Time-to-Treatment ,Sepsis ,03 medical and health sciences ,0302 clinical medicine ,Multidisciplinary approach ,Early Medical Intervention ,medicine ,Humans ,In patient ,Lactic Acid ,Intensive care medicine ,Aged ,Retrospective Studies ,Patient Care Team ,business.industry ,Public health ,030208 emergency & critical care medicine ,Retrospective cohort study ,General Medicine ,Emergency department ,medicine.disease ,United States ,Anti-Bacterial Agents ,Checklist ,Blood Culture ,Healthcare settings ,Emergency Medicine ,Fluid Therapy ,Female ,Guideline Adherence ,Emergency Service, Hospital ,business ,Patient Care Bundles - Abstract
Sepsis is a significant public health crisis in the United States, contributing to 50% of inpatient hospital deaths. Given its dramatic health effects and implications in the setting of new CMS care guidelines, ED leaders have renewed focus on appropriate and timely sepsis care, including timely administration of antibiotics in patients at risk for sepsis. Modeling the success of multidisciplinary bedside huddles in improving compliance with appropriate care in other healthcare settings, a Sepsis Huddle was implemented in a large, academic ED, with the goal of driving compliance with standardized sepsis care as described in the CMS SEP-1 measure. A retrospective cohort analysis was performed, with the primary finding that utilization of the Sepsis Huddle resulted in antibiotics being administered on average 41 min sooner than when the Sepsis Huddle was not performed. Given that literature suggests that early administration of appropriate antibiotic therapy is a major driver of mortality reduction in patients with sepsis, this study represents a proof of concept that utilization of a Sepsis Huddle may serve to improve outcomes among ED patients at risk for sepsis.
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- 2020
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37. Time-Driven Activity-Based Costing of Emergency Department Postdischarge Nurse Calls
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Yingna Liu, Robert S. Kaplan, Maryfran Hughes, Ali S. Raja, Ines Luciani-Mcgillivray, and Brian J. Yun
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Rate of return ,Demographics ,Leadership and Management ,business.industry ,Treatment adherence ,Total cost ,030503 health policy & services ,Strategy and Management ,Health Policy ,Trauma center ,General Medicine ,Emergency department ,03 medical and health sciences ,0302 clinical medicine ,Patient satisfaction ,Nursing ,Medicine ,030212 general & internal medicine ,0305 other medical science ,Activity-based costing ,business - Abstract
EXECUTIVE SUMMARY Postdischarge telephone calls by nurses can decrease patient return rates to healthcare systems. To date, call program costs have not been compared with patient return rates to determine cost-effectiveness. We used time-driven activity-based costing to determine the costs associated with such programs. We developed process maps for a postdischarge nurse call program in the emergency department of an urban, quaternary care, academic, Level 1 trauma center. Our primary outcome was the total cost of calls, which is based on the length of the calls (after 8 hours of observation) and the total capacity rate cost based on national registered nurse salary and space costs. Seven-day return rate differences between patients reached and those not reached from July 2018 to March 2019 were determined with a Z-test. We observed 113 postdischarge calls for 79 patients. The mean (SD) length of calls for patients reached was 4.3 minutes (1.8) compared with 2.6 minutes (0.6) for those not reached. The total capacity rate cost for calls was $1.09/minute, or $4.69 per patient reached and $2.83 per patient not reached. A retrospective analysis of 6,698 patients reached and 6,519 patients not reached showed hospital return rates of 3.5% and 6.3% (p < .0001), respectively. The study findings show that postdischarge calls were associated with decreased return rates to the emergency department and a savings of $134.89 per prevention of one return. In deciding whether to use postdischarge call programs, healthcare systems should also consider the effects on specific demographics and the potential benefits of greater patient satisfaction and increased treatment adherence.
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- 2020
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38. Use of Advanced Imaging for Radiographically Occult Hip Fracture in Elderly Patients: A Systematic Review and Meta-Analysis
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Arya Haj-Mirzaian, Stacy E. Smith, Ramin Khorasani, Pamela T. Johnson, Ali S. Raja, Shadpour Demehri, Adam S. Levin, and John Eng
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Male ,musculoskeletal diseases ,medicine.medical_specialty ,MEDLINE ,Sensitivity and Specificity ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Text mining ,X ray computed ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Fractures, Closed ,Aged ,Aged, 80 and over ,Hip fracture ,medicine.diagnostic_test ,Hip Fractures ,business.industry ,Magnetic resonance imaging ,medicine.disease ,Magnetic Resonance Imaging ,Occult ,Pooled analysis ,030220 oncology & carcinogenesis ,Meta-analysis ,Female ,Radiology ,Tomography, X-Ray Computed ,business - Abstract
Background The overall rate of hip fractures not identified on radiographs but that require surgery (ie, surgical hip fractures) remains unclear in elderly patients who are suspected to have such fractures based on clinical findings. Moreover, the importance of advanced imaging in these patients has not been comprehensively assessed. Purpose To estimate the frequency of radiographically occult hip fracture in elderly patients, to define the higher-risk subpopulation, and to determine the diagnostic performance of CT and bone scanning in the detection of occult fractures by using MRI as the reference standard. Materials and Methods A literature search was performed to identify English-language observational studies published from inception to September 27, 2018. Studies were included if patients were clinically suspected to have hip fracture but there was no radiographic evidence of surgical hip fracture (including absence of any definite fracture or only presence of isolated greater trochanter [GT] fracture). The rate of surgical hip fracture was reported in each study in which MRI was used as the reference standard. The pooled rate of occult fracture, diagnostic performance of CT and bone scanning, and strength of evidence (SOE) were assessed. Results Thirty-five studies were identified (2992 patients; mean age, 76.8 years ± 6.0 [standard deviation]; 66% female). The frequency of radiographically occult surgical hip fracture was 39% (1110 of 2835 patients; 95% confidence interval [CI]: 35%, 43%) in studies of patients with no definite radiographic fracture and 92% (134 of 157 patients; 95% CI: 83%, 98%) in studies of patients with radiographic evidence of isolated GT fracture (moderate SOE). The frequency of occult fracture was higher in patients aged at least 80 years (44%, 529 of 1184), those with an equivocal radiographic report (58%, 71 of 126), and those with a history of trauma (41%, 977 of 2370) (moderate SOE). CT and bone scanning yielded comparable diagnostic performance in the detection of radiographically occult hip fracture (
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- 2020
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39. Patient Experiences With Transfer for Community Hospital Inpatient Admission From an Academic Emergency Department
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Benjamin A. White, Ali S. Raja, Brian J. Yun, Yosef Berlyand, Emily L. Aaronson, David F.M. Brown, Jonathan D. Sonis, and Steven B Pestka
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Health (social science) ,Quality management ,patient satisfaction ,Leadership and Management ,patient feedback ,challenges ,quality improvement ,Patient satisfaction ,emergency medicine ,Patient experience ,Medicine ,access to care ,lcsh:R5-920 ,Ed crowding ,business.industry ,communication ,Health Policy ,Retrospective cohort study ,Emergency department ,Patient Experience Research Briefs ,medicine.disease ,Crowding ,healthcare planning or policy ,Community hospital ,humanities ,Medical emergency ,lcsh:Medicine (General) ,business - Abstract
Emergency department (ED) crowding continues to be a major challenge and has important ramifications for patient care quality. One strategy to decrease ED crowding has been to implement alternative pathways to traditional hospital admission. Through a survey-based retrospective cohort study, we aimed to assess the patient experience for those who agreed to transfer and admission to an affiliated community hospital from a large, academic center’s ED. In all, 85% of participants rated their overall experience as either great or good, 92% did not find it hard to make the decision to be transferred, and 95% found the transfer process itself to be easy.
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- 2020
40. Thoracic Spine Fracture in the Panscan Era
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William R. Mower, Gregory W. Hendey, Brigitte M. Baumann, Robert M. Rodriguez, Sergio Alvarez, Anthony J. Medak, Daniel K. Nishijima, Remy Bizimungu, Ali S. Raja, and Mark I. Langdorf
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Male ,Thoracic ,Radiography ,Wounds, Nonpenetrating ,Injury Severity Score ,0302 clinical medicine ,Medicine ,030212 general & internal medicine ,Tomography ,Lumbar Vertebrae ,medicine.diagnostic_test ,Accidents, Traffic ,Injuries and accidents ,Middle Aged ,X-Ray Computed ,Scapula ,Hospitalization ,Motorcycles ,Blunt trauma ,Wounds ,Cervical Vertebrae ,Emergency Medicine ,Spinal Fractures ,Radiography, Thoracic ,Female ,Presentation (obstetrics) ,musculoskeletal diseases ,Adult ,medicine.medical_specialty ,Physical Injury - Accidents and Adverse Effects ,Rib Fractures ,Thoracic Injuries ,Clinical Sciences ,Thoracic Vertebrae ,03 medical and health sciences ,Clinical Research ,Humans ,Nonpenetrating ,Traffic ,Mortality ,Aged ,Pedestrians ,Hemothorax ,Multiple Trauma ,business.industry ,Neurosciences ,030208 emergency & critical care medicine ,Emergency department ,Length of Stay ,Thoracic spine fracture ,Clavicle ,Emergency & Critical Care Medicine ,Confidence interval ,Surgery ,Good Health and Well Being ,Accidents ,Injury (total) Accidents/Adverse Effects ,Accidental Falls ,Tomography, X-Ray Computed ,business ,Chest radiograph - Abstract
STUDY OBJECTIVE:In the current era of frequent chest computed tomography (CT) for adult blunt trauma evaluation, many minor injuries are diagnosed, potentially rendering traditional teachings obsolete. We seek to update teachings in regard to thoracic spine fracture by determining how often such fractures are observed on CT only (ie, not visualized on preceding trauma chest radiograph), the admission rate, mortality, and hospital length of stay of thoracic spine fracture patients, and how often thoracic spine fractures are clinically significant. METHODS:This was a preplanned analysis of prospectively collected data from the NEXUS Chest CT study conducted from 2011 to 2014 at 9 Level I trauma centers. The inclusion criteria were older than 14 years, blunt trauma occurring within 6 hours of emergency department (ED) presentation, and chest imaging (radiography, CT, or both) during ED evaluation. RESULTS:Of 11,477 enrolled subjects, 217 (1.9%) had a thoracic spine fracture; 181 of the 198 thoracic spine fracture patients (91.4%) who had both chest radiograph and CT had their thoracic spine fracture observed on CT only. Half of patients (49.8%) had more than 1 level of thoracic spine fracture, with a mean of 2.1 levels (SD 1.6 levels) of thoracic spine involved. Most patients (62%) had associated thoracic injuries. Compared with patients without thoracic spine fracture, those with it had higher admission rates (88.5% versus 47.2%; difference 41.3%; 95% confidence interval 36.3% to 45%), higher mortality (6.3% versus 4.0%; difference 2.3%; 95% confidence interval 0 to 6.7%), and longer length of stay (median 9 versus 6 days; difference 3 days; P
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- 2020
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41. Beyond the Maslach burnout inventory: addressing emergency medicine burnout with Maslach's full theory
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Ali S. Raja, James K. Takayesu, Joshua J Baugh, and Benjamin A. White
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medicine.medical_specialty ,Physician Wellness ,burnout ,education ,Stressor ,lcsh:Medical emergencies. Critical care. Intensive care. First aid ,Specialty ,physician experience ,Workload ,lcsh:RC86-88.9 ,Interpersonal communication ,Burnout ,medicine.disease ,Maslach burnout inventory ,moral injury ,Workforce ,Emergency medicine ,medicine ,Attrition ,Moral injury ,Psychology ,psychological phenomena and processes ,Concepts - Abstract
Burnout, a psychological syndrome emerging as a prolonged response to chronic interpersonal stressors on the job, remains a substantial problem for emergency physicians, leading to decreased quality of care and attrition from the workforce. The majority of prior work on burnout in emergency medicine has focused on individualized solutions, which have demonstrated modest efficacy for ameliorating burnout. However, recent studies suggest that burnout in medicine is primarily caused by workplace factors (eg, unmanageable workloads, unreasonable time pressures) and therefore requires solutions at an organizational level. In her decades of research across industries, Christina Maslach identified 6 domains of organizations that can either promote engagement or lead to burnout. In this article, we apply Maslach's 6 domains to emergency medicine to provide a systematic framework for alleviating burnout and promoting engagement among emergency physicians. By considering the domains of workload, reward, control, fairness, community, and value congruence, emergency medicine leaders can develop and deploy more effective interventions aimed at improving the experience and longevity of physicians across our specialty.
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- 2020
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42. ACR Appropriateness Criteria® Major Blunt Trauma
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Ali S. Raja, Expert Panel on Major Trauma Imaging, Deborah B. Diercks, Walter L. Biffl, Mark E. Lockhart, Benjamin J. Meyer, Faisal Khosa, Jeffrey Y. Shyu, Jorge A. Soto, Marc A Camacho, Ali Salim, Phyllis Glanc, Thomas Ptak, O. Clark West, Sanjeeva P. Kalva, and Bharti Khurana
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medicine.medical_specialty ,business.industry ,Major trauma ,medicine.disease ,Polytrauma ,Appropriate Use Criteria ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Blunt trauma ,Multidisciplinary approach ,030220 oncology & carcinogenesis ,medicine ,Radiology, Nuclear Medicine and imaging ,Intensive care medicine ,Grading (education) ,business ,Medical literature - Abstract
This review assesses the appropriateness of various imaging studies for adult major blunt trauma or polytrauma in the acute setting. Trauma is the leading cause of mortality for people in the United States The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
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- 2020
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43. Impact of Urgent Care Openings on Emergency Department Visits to Two Academic Medical Centers Within an Integrated Health Care System
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Margaret E. Samuels-Kalow, Michael R. Wilson, Lucas C. Carlson, Marc J. Shapiro, Jungyeon Kim, Jarone Lee, Ali S. Raja, David F.M. Brown, Daniel A. Dworkis, and Brian J. Yun
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Adult ,Male ,Urgent Cares ,MEDLINE ,Logistic regression ,Ambulatory Care Facilities ,Health Services Accessibility ,Odds ,03 medical and health sciences ,0302 clinical medicine ,Health care ,medicine ,Humans ,030212 general & internal medicine ,Aged ,Academic Medical Centers ,Spatial Analysis ,Delivery of Health Care, Integrated ,business.industry ,030208 emergency & critical care medicine ,Odds ratio ,Emergency department ,Middle Aged ,Patient Acceptance of Health Care ,medicine.disease ,Confidence interval ,Emergency Medicine ,Female ,Medical emergency ,Emergency Service, Hospital ,business ,Boston - Abstract
Study objective The effect of urgent cares on local emergency department (ED) patient volumes is presently unknown. In this paper, we aimed to assess the change in low-acuity ED utilization at 2 academic medical centers in relation to patient proximity to an affiliated urgent care. Methods We created a geospatial database of ED visits occurring between April 2016 and March 2018 to 2 academic medical centers in an integrated health care system, geocoded by patient home address. We used logistic regression to characterize the relationship between the likelihood of patients visiting the ED for a low-acuity condition, based on ED discharge diagnosis, and urgent care center proximity, defined as living within 1 mile of an open urgent care center, for each of the academic medical centers in the system, adjusting for spatial, temporal, and patient factors. Results We identified a statistically significant reduction in the likelihood of ED visits for low-acuity conditions by patients living within 1 mile of an urgent care center at 1 of the 2 academic medical centers, with an adjusted odds ratio of 0.87 (95% confidence interval 0.78 to 0.98). There was, however, no statistically significant reduction at the other affiliated academic medical center. Further analysis showed a statistically significant temporal relationship between time since urgent care center opening and likelihood of a low-acuity ED visit, with approximately a 1% decrease in the odds of a low-acuity visit for every month that the proximal urgent care center was open (odds ratio 0.99; 95% confidence interval 0.985 to 0.997). Conclusion Although further research is needed to assess the factors driving urgent care centers' variable influence on low-acuity ED use, these findings suggest that in similar settings urgent care center development may be an effective strategy for health systems hoping to decrease ED utilization for low-acuity conditions at academic medical centers.
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- 2020
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44. Turning around cancer: Oncology imaging and implications for emergency department radiology workflow
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Marc D. Succi, McKinley Glover, Michael H. Lev, Ali S. Raja, Sishir Rao, Benjamin A. White, Brian J. Yun, Sevith Rao, Anand M. Prabhakar, and Ravi V. Gottumukkala
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Male ,medicine.medical_specialty ,Time Factors ,Radiology workflow ,education ,Computed tomography ,Medical Order Entry Systems ,Workflow ,03 medical and health sciences ,0302 clinical medicine ,Matched cohort ,Neoplasms ,medicine ,Humans ,Retrospective Studies ,Cancer staging ,Radiology Department, Hospital ,medicine.diagnostic_test ,Multivariable linear regression ,business.industry ,Cancer ,030208 emergency & critical care medicine ,General Medicine ,Emergency department ,Length of Stay ,Middle Aged ,medicine.disease ,Emergency Medicine ,Female ,Radiology ,Triage ,Completion time ,Emergency Service, Hospital ,Tomography, X-Ray Computed ,business ,Boston - Abstract
Oncologic imaging in the emergency department (ED) is frequently encountered, including non-acute scans known as "metastatic workups" or "staging" (referred to as "cancer staging computed tomography (CT) exams"). This study examines the impact of oncologic staging CT exams on ED imaging turnaround time (TAT), defined as the time from the end of the CT exam to a final signed radiologist report, as well as order to scan completion time.A retrospective review was conducted of all adult patients presenting to an urban, quaternary academic medical center ED from February 2016 to September 2017, who had CT imaging ordered, performed, and interpreted in the ED imaging department. CT exams containing institution-specific cancer descriptors were included. After excluding all acute exams, cancer staging CT exams were compared to a matched cohort of non-oncologic ED CT exams to evaluate median TAT and order to scan completion time using a log transformed multivariable linear regression.Adjusting for age and CT body part, cancer staging CT exams were associated with an independently statistically significant increased median log TAT compared to non-oncologic ED CT exams (114.5 min [IQR 112] versus 69 min [IQR 67], respectively, p .0001) and an independently statistically significant increased median log initial order to scan completion time (166 min [IQR: 89] vs 119 min [IQR: 93], p .0001).Oncology patients receiving non-acute metastatic workup scans in the ED have a significantly longer TAT compared to non-oncologic ED CT exams as well as longer order to scan completion times.
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- 2020
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45. Prostatic Artery Embolization Using 100–300-μm Trisacryl Gelatin Microspheres to Treat Lower Urinary Tract Symptoms Attributable to Benign Prostatic Hyperplasia: A Single-Center Outcomes Analysis with Medium-Term Follow-up
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Toby C. Chai, Ralph Devito, Steven Schoenberger, Ali S. Raja, Lawrence H. Staib, Raj Ayyagari, Shivank Bhatia, Julius Chapiro, and T. Powell
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medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Urology ,Hyperplasia ,medicine.disease ,Single Center ,Prostatic artery embolization ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Prostate cancer ,0302 clinical medicine ,Quality of life ,Lower urinary tract symptoms ,030220 oncology & carcinogenesis ,Medicine ,Radiology, Nuclear Medicine and imaging ,International Prostate Symptom Score ,Embolization ,Cardiology and Cardiovascular Medicine ,business - Abstract
Purpose To report medium-term outcomes of prostatic artery embolization (PAE) using 100–300-μm trisacryl gelatin microspheres to treat lower urinary tract symptoms (LUTS) from benign prostatic hyperplasia (BPH) and to evaluate how cone-beam computed tomography-measured prostate gland volume (PGV), median lobe enlargement (MLE), age, and Charlson Comorbidity Index (CCI) affect these results. Materials and Methods Seventy-four consecutive patients who underwent PAE from April 2014 through August 2018 were retrospectively reviewed. Patients had International Prostate Symptom Score (IPSS) >12, Quality of Life (QoL) score >2, prostate gland volume (PGV) >40 mL, age older than 45 years, and medical therapy failure. Twelve patients were excluded for bladder pathology or prostate cancer. Patients (n = 62, age = 71.8 ± 9.3 years, CCI = 3.5 ± 1.7, PGV = 174 ± 110 mL) had pre-procedure IPSS = 22.4 ± 5.6, QoL score = 4.4 ± 0.9, and post-void residual (PVR) = 172 ± 144 mL. Post-procedure values were compared to baseline at 1, 3, 6, 12, and 24 months. Associations between outcomes and PGV, MLE, age, and CCI were evaluated. Adverse event recording used Clavien-Dindo classification. Results One month after PAE (n = 37), IPSS improved to 7.6 ± 5.2 (P Conclusions PAE with 100–300-μm microspheres produced sustained substantial improvements in LUTS, PGV, and PVR, which were independent of baseline PGV, MLE, age, or CCI.
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- 2020
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46. Correction: The Story of #GetMePPE and GetUsPPE.org to Mobilize Health Care Response to COVID-19 : Rapidly Deploying Digital Tools for Better Health Care
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Shuhan He, Ayotomiwa Ojo, Adam L Beckman, Suhas Gondi, Megan Ranney, Marian Betz, Jeremy S Faust, Esther Choo, Dara Kass, and Ali S Raja
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Health Informatics - Published
- 2023
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47. Nudging Emergency Department-Initiated Addiction Treatment
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B. White, Sarah E. Wakeman, Bryan D. Hayes, Alister Martin, Ted Robertson, Tyler Chavez, Kelley Butler, Sayon Dutta, Jess Leifer, Lee-Sien Kao, Jeremy Barofsky, Ali S. Raja, and Jaclyn Lefkowitz
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medicine.medical_specialty ,Referral ,business.industry ,Narcotic Antagonists ,Psychological intervention ,Opioid use disorder ,Emergency department ,medicine.disease ,Opioid-Related Disorders ,Confidence interval ,Buprenorphine ,Psychiatry and Mental health ,Intervention (counseling) ,Ambulatory ,Emergency medicine ,medicine ,Opiate Substitution Treatment ,Humans ,Pharmacology (medical) ,business ,Emergency Service, Hospital ,medicine.drug - Abstract
OBJECTIVES When initiated in the Emergency Department (ED), medication for addiction treatment (MAT) with buprenorphine improves outcomes, increases engagement in addiction treatment and decreases the use of inpatient addiction treatment services. Unfortunately, initiating MAT in the ED is not yet standard practice. We assessed the impact of the addition of a multipart behavioral science-based intervention to increase opioid use disorder (OUD)-related treatments prescribed in the ED. METHODS Our ED initiated a campaign to help ED faculty obtain their DEA-X waiver required to prescribe buprenorphine. In parallel, we implemented 2 ED-initiated buprenorphine treatment pathways. We then conducted a two-stage qualitative process informed by behavioral science to identify key barriers to physician use of the MAT protocol. Using these insights, we developed 4 behavioral science-based interventions. To assess the impact of the interventions on the number of OUD-related treatments per day among patients meeting the inclusion criteria we compared the number of OUD-related treatments per day before versus after the interventions began using t tests. Then, in our primary model, we estimated the causal effect of the behavioral interventions using a regression discontinuity in time approach. RESULTS Across the entire year study period, there is an increase in OUD-related treatment after the interventions begin, driven by greater use of ambulatory referral orders. The unadjusted mean difference in any OUD treatments per day pre- versus post-intervention increased by 0.80 (95% confidence interval [CI]: 0.04, 1.56; P = 0.039) whereas the number of ambulatory referral orders placed increased by 0.82 (95% CI: 0.48, 1.16; P
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- 2021
48. Trends in Racial and Gender Profiles of United States Academic Emergency Medicine Faculty: Cross-Sectional Survey From 2007 to 2018
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Ali Tariq Shaikh, Michelle D. Lall, Sabeena Jalal, Ali S. Raja, Saleh Fares, Javed Siddiqi, and Faisal Khosa
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Emergency Medicine - Abstract
Numerous studies have reported existing disparities in academic medicine. The purpose of this study was to assess racial and gender disparity in academic emergency medicine (EM) faculty positions across the United States from 2007 to 2018.The primary objective was to identify the racial and ethnic and gender distributions across academic ranks in EM. The secondary objective was to describe the racial and gender proportions across different tenure tracks and degrees.We conducted a retrospective analysis using data from the Association of American Medical Colleges. Simple descriptive statistics and time series analysis were employed to assess the trends and relationship between race and gender across academic rank, type of degree, and tenure status.When averaged, 75% of all faculty members were White physicians and 67.5% were male. Asian faculty members showed an increased representation in the lower academic ranks and underrepresented minority groups demonstrated a small increase. Asian faculty members demonstrated a significantly increasing trend at the level of instructor (t = 0.02; p = 0.034; 95% CI 0.05-1.03). Female faculty members showed a significantly decreasing trend over the study period (t = -0.01; p0.001; 95% CI 0.68-0.75). White academic physicians and male faculty members made up most of all degree types and tenure categories.Despite an increase in proportional representation, the underrepresentation of female faculty members and those from minority groups persists in emergency medicine. Further studies are needed to identify and address the root causes of these differences.
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- 2021
49. Mobile app helps trainees manage emergencies at the bedside
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Ali S. Raja, Yonatan G. Keschner, Christopher W. Baugh, Jared Conley, Andrew L. Chu, Lucinda Lai, Joshua J Baugh, Paul D. Biddinger, and Eric M. Isselbacher
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Innovations Report ,Cath lab ,Coronavirus disease 2019 (COVID-19) ,business.industry ,Mobile apps ,Design thinking ,Emergency Nursing ,medicine.disease ,Digital health ,Education ,Intervention (counseling) ,Emergency Medicine ,Medicine ,Medical emergency ,Medical diagnosis ,business ,Point of care - Abstract
BACKGROUND: Although emergency departments (ED) have standardized guidelines for low‐frequency, high‐acuity diagnoses, they are not immediately accessible at the bedside, and this can cause anxiety in trainees and delay patient care. This problem is exacerbated during events like COVID‐19 that require the rapid creation, iteration, and dissemination of new guidelines. METHODS: Physician innovators used design thinking principles to develop EM Protocols (EMP), a mobile application that clinicians can use to immediately view guidelines, contact consultants (e.g., cath lab activation), and access code‐running tools. The project became an institutional high priority, because it helps EM trainees and off‐service rotators manage low‐frequency, high‐acuity emergencies at the point of care, and its COVID‐19 guidelines can be rapidly updated and disseminated in real time. RESULTS: This intervention was deployed across two academic medical centers during the COVID‐19 surge. Nearly 300 ED clinicians have downloaded EMP, and they have interacted with the app over 5,400 times. It continues to be used regularly, over 12 months after the initial surge. Since the app was received positively, there are efforts to build in additional adult and pediatric guidelines. DISCUSSION: Digital health tools like EMP can serve as invaluable adjuncts for managing acute, life‐threatening emergencies at the point of care. They can benefit trainees during normal day‐to‐day operations as well as scenarios that cause large‐scale operational disruptions, such as natural disasters, mass casualty events, and future pandemics.
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- 2021
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50. Effectiveness of an anti-fog polymer coating in protective eyewear: a blinded, randomised controlled cross-over trial with healthcare providers in an emergency department setting
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Yonatan G Keschner, Ali S Raja, Justin D Margolin, Hui Zheng, and Kristian R Olson
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General Medicine - Abstract
BackgroundEye protection is a mandatory component of the personal protective equipment in healthcare settings, especially for suspected or confirmed cases of COVID-19 and during aerosolising procedures. Fogging of protective eyewear is a frequent problem experienced by providers. The hydrophilic property of a sulfonated polymer, BiaXam, may be able to decrease fogging through wicking moisture from the lens. In this study, we tested the anti-fogging properties of this polymer when applied to protective eyewear.MethodsAn investigator-initiated prospective, randomised, single-blinded cross-over study was conducted in an emergency department in a large, tertiary care hospital. Participants were blinded and randomised first to either a pair of anti-fog coated or uncoated eyewear, and then to the alternative pair after 2 hours. Study participants completed an identical survey at the end of each 2-hour period.Results50 emergency medicine healthcare providers were enrolled and 48 completed the study. Results demonstrated a significant difference in fogging between the coated and uncoated eyewear, as 81% of the participants reported fogging of the uncoated lenses and only 55% of the participants reported fogging in the coated pair (p=0.0029). Participants reported that the uncoated lenses fogged two times as frequently on a 10-point Likert scale (4.5±3.3 vs 2.1±2.5; pConclusionOverall, sulfonated polymer-coated eyewear improved provider visualisation, user experience and perceived mitigation of potential medical errors.
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- 2022
- Full Text
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