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12 results on '"Borst, H."'

1. The fate of gene modified T-cells can be followed in 2 patients after PBSCT

Author

Weissinger E, Silvani A, Radrizzani M, Benati C, Ebeling S, Borst H, Stampino CG, BONINI , MARIA CHIARA, CICERI , FABIO, Neuhoff N, Bock O, Ganser A, Hertenstein B., Weissinger, E, Silvani, A, Radrizzani, M, Benati, C, Ebeling, S, Borst, H, Stampino, Cg, Bonini, MARIA CHIARA, Ciceri, Fabio, Neuhoff, N, Bock, O, Ganser, A, and Hertenstein, B.

Published
2003

2. Analysis of an infill scenario for Rotterdam. Traffic noise, air pollution, and public health in relation to urban density and traffic of cars and bicycles

Author

Schaminée, S., Rietveld, E., Salomons, E., Kluizenaar, Y. de, Borsboom, J., Borst, H., and Guit, M.

Subjects
Urban Development, Earth & Environment, UES - Urban Environment & Safety, Acoustics and Audiology Health, Built Environment, EELS - Earth, Environmental and Life Sciences
Abstract

An analysis is presented of various elements of an infill scenario for the center of Rotterdam in the year 2030, corresponding to a population increase from about 30,000 to 60,000 inhabitants. We have implemented detailed future building designs in our software instrument Urban Strategy, and calculated consequences for traffic congestion, urban density, noise, and air pollution. Urban density increases considerably in the city center, which is generally considered positive for urban sustainability (economically and socially). The results for noise and air pollution are less positive. We find that the number of inhabitants that is highly annoyed by traffic noise increases. The corresponding health effect is estimated as equivalent to 100 life years lost per year. This may be used as an argument for reductions of motorized traffic in the city center. To achieve such reductions, the city of Rotterdam intends to implement various policies aimed at discouraging car use and supporting bicycles and public transport. A modal shift from car to bicycle will have positive effects not only on congestion, traffic noise, and air pollution, but also on public health due to enhanced physical activity. We calculated that the latter effect is a gain of 200 life years per year.

Published
2012

4. Sound propagation in cities

Author

Salomons, E.M., Polinder, H., Lohman, W., Zhou, H., Borst, H., and TNO Bouw en Ondergrond

Subjects
Multiple diffraction, Urban traffic noise, Multiple reflections, Sound level, Numerical and experimental study, Traffic noise, Sound propagation, Noise annoyance, Street canyon, Acoustic variables control, Computer integrated manufacturing, Urban Development, Noise pollution, Current models, Engineering models, Amsterdam, Built Environment, Acoustic wave propagation, Acoustic noise, Noise exposure
Abstract

A new engineering model for sound propagation in cities is presented. The model is based on numerical and experimental studies of sound propagation between street canyons. Multiple reflections in the source canyon and the receiver canyon are taken into account in an efficient way, while weak reflections by distant buildings involving multiple diffraction are neglected. An application of the new model to traffic noise in the city of Amsterdam is presented. Distributions of noise exposure of inhabitants are presented. The influence of quiet sides of dwellings on noise annoyance is discussed. While current models for urban traffic noise tend to underestimate sound levels at quiet sides, the new model is expected to provide more accurate levels at quiet sides.

Published
2009

5. An unidentified TeV source in the vicinity of Cygnus OB2

Author

Aharonian, F., Akhperjanian, A., Beilicke, M., Bernlohr, K., Borst, H., Bojahr, H., Bolz, O., Coarasa, T., Contreras, J., Cortina, J., Denninghoff, S., Fonseca, V., Girma, M., Gotting, N., Heinzelmann, G., Hermann, G., Heusler, A., Hofmann, W., Horns, D., Jung, I., Kankanyan, R., Kestel, M., Kettler, J., Kohnle, A., Konopelko, A., Kornmeyer, H., Kranich, D., Krawczynski, H., Lampeitl, H., Lopez, M., Lorenz, E., Lucarelli, F., Magnussen, N., Mang, O., Meyer, H., Milite, M., Mirzoyan, R., Moralejo, A., Ona, E., Panter, M., Plyasheshnikov, A., Prahl, J., Puhlhofer, G., Rauterberg, G., Reyes, R., Rhode, W., Ripken, J., Rohring, A., Rowell, G. P., Sahakian, V., Samorski, M., Schilling, M., Schroder, F., Siems, M., Sobzynska, D., Stamm, W., Tluczykont, M., Volk, H. J., Wiedner, C. A., Wittek, W. (HEGRA Collaboration), Uchiyama, Yasunobu, and Takahashi, Tadayuki

Subjects
Physics, Astrophysics (astro-ph), Flux, HEGRA, FOS: Physical sciences, Astronomy and Astrophysics, Radius, Astrophysics, Particle acceleration, Stars, Pulsar, Space and Planetary Science, Cygnus OB2, Heliosphere
Abstract

著者人数：62名, Accepted: 2002-08-09, 資料番号: SA1002274000

Published
2002
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7. Drug- and disease-induced changes of human cardiac beta 1- and beta 2-adrenoceptors

Author

Brodde, O. E., Zerkowski, H. R., Borst, H. G., Maier, W., Michel, M. C., and Other departments

Subjects
cardiovascular system
Abstract

Cardiac beta-adrenoceptor density and subtype distribution has been determined in different kinds of heart failure. A decrease in cardiac beta-adrenoceptor function appears to be a general phenomenon in all kinds of heart failure. However, cardiac beta 1- and beta 2-adrenoceptors seem to be differentially affected in different kinds of heart failure: while in end-stage idiopathic dilated cardiomyopathy the diminished cardiac beta-adrenoceptor function is due to a selective loss in beta 1-adrenoceptors, in mitral valve disease, tetralogy of Fallot and end-stage ischaemic cardiomyopathy it is characterized by a concomitant reduction in beta 1- and beta 2-adrenoceptors. Chronic treatment of heart failure patients with beta-adrenoceptor antagonists leads to an up-regulation of cardiac beta-adrenoceptors, but in a subtype-selective fashion: beta 1-selective antagonists increase only cardiac beta 1-adrenoceptors, whereas non-selective antagonists increase both beta 1- and beta 2-adrenoceptors. Such a (subtype-selective) 'recovery' of cardiac beta-adrenoceptors may be one reason for the beneficial effects of low-dose beta-adrenoceptor antagonist treatment in patients with severe heart failure

Published
1989

9. CMS: The Compact Muon Solenoid: Letter of intent for a general purpose detector at the LHC

Author

Della Negra, M., Markytan, M., Neumeister, N., Porth, P., Rohringer, H., Strauss, J., Szoncso, F., Walzel, G., Wulz, C. E., Sacton, J., Vander Velde, C., Vilain, P., Wilquet, G., Lemonne, J., Tavernier, S., Doninck, Walter, Wulleman, J., Favart, D., Gregoire, G., Wolf, E., Verbeure, F., Daubie, E., Grard, F., Pingot, O., Windmolders, R., Chekhlova, N., Kuzhir, P., Litomin, A., Shumeiko, N., Shvarkov, D., Soroko, A., Kuchinsky, P., Lomako, V., Petrov, V., Prosolovich, V., Kuchinsky, Yu, Kutilin, A., Rumyantsev, V., Sergeenko, M., Genchev, V., Traynov, R., Yaidzhiev, P., Jordanov, A., Litov, L., Roumen Tsenov, Velev, V., Ainsaar, A., Aguraiuja, R., Engelbrecht, K., Hall, A., Lippmaa, E., Lippmaa, J., Mets, U., Piksarv, P., Pikver, R., Subbi, J., Teeaar, R., Uustalu, E., Villemson, R., Gustafsson, K., Hentinen, A., Honkavaara, K., Huhtinen, M., Ikonen, J. P., Karhu, P., Karimaki, V., Karttaavi, T., Kettunen, H., Kurvinen, K., Kuuri, J., Lappalainen, J., Lauhakangas, R., Makela, J., Niemi, M., Oksakivi, T., Orava, R., Pimia, M., Roth, W., Schulman, T., Simonen, S., Sarme, T., Tuuva, T., Vertanen, O., Voutilainen, M., Aarnio, P. A., Ekman, K., Onnela, A., Salonen, M., Sell, J., Hattula, J., Julin, R., Ruuskanen, V., Aysto, J., Stalnacke, J., Suhonen, E., Kinnunen, R., Tuominiemi, J., Brenner, R., Osterberg, K., Perret-Gallix, D., Schneegans, M., Thenard, J. M., Vialle, J. P., Antilogus, P., Bedjidian, M., Contardo, D., Drapier, O., El Mamouni, H., Haroutunian, R., Ille, B., Kryn, D., Mirabito, L., Smadja, G., Badier, J., Bonneaud, G., Busata, A., Busson, P., Charlot, C., Chaurand, B., Dobrzynski, L., Dechandol, C., Gregory, C., Karar, A., Kluberg, L., Lemoine, C., Matricon, P., Morinaud, G., Romana, A., Tanaka, R., Baze, J. M., Desportes, H., Duthil, R., Lesmond, C., Lottin, J. C., Pabot, Y., Denegri, D., Bareyre, P., Faure, J. L., Lemoigne, Y., Pansart, J. P., Blaes, R., Brom, J. M., Geist, Walter M., Gorodetzky, P., Juillot, P., Kachelhoffer, T., Lazic, D., Michalon, A., Michalon-Mentzer, M. E., Racca, C., Riester, J. L., Voltolini, C., Iashvili, I., Kharchilava, A., Roinishvili, N., Roinishvili, V., Rurua, L., Amaglobeli, N., Glonti, L., Kartvelishvili, V., Kvatadze, R., Metreveli, Z., Shanidze, R., Chikovani, E., Faissner, H., Moers, T., Priem, R., Razen, B., Rein, D., Reithler, H., Schleichert, R., Schwarthoff, H., Tuchscherer, H., Wagner, H., Borst, H. G., Dau, W. D., Siegmon, G., Merlo, J. P., Glass, J., Klefenz, F., Manner, R., Wurz, A., Kokkinias, P., Markou, A., Siotis, I., Spyropoulou, M., Vassiliadis, G., Vayaki, A., Zevgolatakos, E., Resvanis, L., Evangelou, I., Manthos, N., Siolios, N., Triantis, F. A., Bencze, G., Denes, Ervin, Urban, L., Vesztergombi, G., Cavanna, F., Piano Mortari, Giovanni, Verdecchia, M., Bozzo, M., Caso, C., Fabbricatore, P., Gemme, G., Morettini, G., Musenich, R., Parodi, R., Ridolfi, G., Sette, G., Zhang, B., Bettini, A., Busetto, G., Centro, S., Conti, E., Gasparini, F., Gasparini, U., Lippi, I., Martinelli, R., Meneguzzo, A. T., Michelotto, M., Pegorado, M., Sartori, P., Ventura, L., Zotto, P., Zumerle, G., Jacubaitis, E., Berson, T., Gailitis, A., Krotkus, A., Vengalis, B., Anisauskas, S., Bogdanovich, P., Kaniauskas, J., Norvaisas, E., Rudzikas, Z., Dominik, W., Krolikowski, J., Konecki, M., Ropelewski, L., Gorski, M., Szeptycka, M., Bordalo, P., Lourenco, C., Nobrega, R., Ramos, S., Varela, J., Akishin, P., Andreev, S., Belkov, A., Bondila, M., Chalyshev, V., Cheremukhin, A., Chernenko, N., Eidelman, B., Eremin, V., Evsikov, I., Fadeev, N., Feshchenko, A., Fefelova, E., Golubykh, S., Golutvin, I., Ivanchenko, I., Ivanyutin, L., Ivanov, V., Kalagin, V., Kharlamov, V., Khasanov, A., Kotikov, A., Kozenkova, Z., Kozlov, Y., Krivokhizhin, V., Lanyov, A., Losanu, S., Lukyanov, I., Medved, K., Merkin, I., Minashkin, V., Moisenz, P., Nogaitsev, A., Panasik, V., Peshekhonov, D., Pusinin, I., Rashevsky, R., Savin, Igor A., Sergeev, S., Shabratova, G., Sidorov, A., Smirnov, G., Susova, N., Vasilesku, A., Verbitskaya, E., Yaremchuk, A., Yarygin, G., Yudin, I., Zamyatin, N., Zrelov, P., Zubarev, E., Zverolovlev, V., Demidov, V., Demidova, E., Kaftanov, V., Kubantsev, M., Lublev, E., Nikitenko, A., Nikitin, A., Safronov, G., Semechkin, V., Semenov, Yu, Starodumov, A., Stepanov, N., Trebukhovsky, Yu, Atoian, G. S., Akopian, M. V., Fomenko, A. A., Gninenko, S. N., Gushin, E. V., Isakov, V. V., Lebedev, V. A., Kovzelev, A. V., Musienko, Yu V., Poblaguev, A. A., Proskuryakov, A. L., Sukhov, V. V., Bodyagin, V., Bravina, L., Kodolova, Olga, Korotkikh, V., Kruglov, N., Larychev, A., Murzin, V., Proskuryakov, A., Sarycheva, L., Sinev, N., Zabrodin, E., Zhukov, V., Baranov, P. S., Belousov, A. S., Lebedev, A. I., Rusakov, S. V., Bityukov, S., Buzulutskov, A., Goncharov, P., Gorin, A., Gurzhiev, A., Dyshkant, A., Efimov, A., Evdokimov, N., Korneev, Yu, Kostritsky, A., Krinitsyn, A., Kryshkin, V., Obramov, V., Obraztsov, V., Ostankov, A., Podstavkov, V., Rykalin, V., Turchanovich, L., Zaichenko, A., Amon, S., Brajnik, D., Korbar, D., Stanovnik, A., Staric, M., Ferrando, A., Martinez-Laso, L., Albajar, C., Demoulin, M., Eggert, K., Fucci, A., Givernaud, A., Inkinen, S., Jank, W., Meyer, T., Plothow-Besch, H., Porte, J. P., Racz, A., Radermacher, E., Samyn, D., Taylor, G., Wrochna, G., Barillere, R., Carminati, F., Christiansen, J., D Ambrosio, C., Gayde, J. C., Gerwig, H., Giani, S., Goulas, I., Gys, T., Hauviller, C., Heijne, E., Herve, Alain, Jarron, P., Lassila-Perini, K., Lasseur, C., Lecoq, P., Le Goff, J. M., Lemeilleur, F., Letheren, M., Lofstedt, B., Mackenzie, R., Marchioro, A., Meddeler, Gerrit Jan, Price, M., Schonbacher, H., Stevenson, G., Verweij, H., Vuoskoski, J., Brown, Robert M., Cragg, D. A., Cockerill, D. J. A., Denton, L. G., French, M., Grayer, G. H., Jeffreys, P. W., Madani, S. M., Barber, G., Beuselinck, R., Binnie, D. M., Cameron, W., Cataneo, M., Clayton, E., Gentry, D., Gill, K., Hall, G., Hassard, J., Margetides, S., Miller, David J., Price, D., Streibig, J., Raymond, M., Sedgbeer, J. K., Seez, Chris J., Wheadon, R., Virdee, T. S., Clarke, P., Hobson, P., Imrie, D., Mckemey, A., Watts, S., Chaney, R. C., Fenyves, E. Y., Friedrich, J., Hammack, H., Johnson, N., Orgeron, J., Breedon, R., Ko, W., Lander, R., Atac, M., Chrisman, D., Cline, D., Lazic, S., Otwinowski, S., Liu, Y., Dittmar, M., Gary, J. W., Gorn, W., Jui, C. C. H., Layter, J. G., Shen, B. C., Vandalen, Gordon J., Wilson, G. W., Aitov, R., Avezov, A., Gafarov, A., Koblik, Yu, Mirkarimov, D., Pirogov, V., Safarov, R., Urkenbaev, A., Yuldashev, B., and Yunusov, K.

11. Evidence for TeV gamma ray emission from Cassiopeia A

Author

Aharonian, F., Akhperjanian, A., Barrio, J., Bernlohr, K., Borst, H., Bojahr, H., Bolz, O., Contreras, J., Cortina, J., Denninghoff, S., Fonseca, V., Gonzalez, J., Gotting, N., Heinzelmann, G., Hermann, G., Heusler, A., Hofmann, W., Horns, D., Ibarra, A., Iserlohe, C., Jung, I., Kankanyan, R., Kestel, M., Kettler, J., Kohnle, A., Konopelko, A., Kornmeyer, H., Kranich, D., Krawczynski, H., Lampeitl, H., Marcos López Moya, Lorenz, E., Lucarelli, F., Magnussen, N., Mang, O., Meyer, H., Mirzoyan, R., Moralejo, A., Ona, E., Padilla, L., Panter, M., Plaga, R., Plyasheshnikov, A., Prahl, J., Puhlhofer, G., Rauterberg, G., Rohring, A., Rhode, W., Rowell, G. P., Sahakian, V., Samorski, M., Schilling, M., Schroder, F., Siems, M., Stamm, W., Tluczykont, M., Volk, H. J., Wiedner, C. A., and Wittek, W.

Subjects
Physics, Spectral index, Astrophysics::High Energy Astrophysical Phenomena, Astrophysics (astro-ph), Gamma ray, FOS: Physical sciences, HEGRA, Astronomy and Astrophysics, Cosmic ray, Astrophysics, law.invention, Cassiopeia A, Telescope, Space and Planetary Science, law, High Energy Physics::Experiment, Supernova remnant, Cherenkov radiation, Astrophysics::Galaxy Astrophysics
Abstract

232 hours of data were accumulated from 1997 to 1999, using the HEGRA Stereoscopic Cherenkov Telescope System to observe the supernova remnant Cassiopeia A. TeV gamma ray emission was detected at the 5 sigma level, and a flux of (5.8 +- 1.2(stat) +- 1.2(syst)) 10^(-9) ph m^(-2) s^(-1) above 1 TeV was derived. The spectral distribution is consistent with a power law with a differential spectral index of -2.5 +- 0.4(stat) +- 0.1(syst) between 1 and 10 TeV. As this is the first report of the detection of a TeV gamma ray source on the "centi-Crab" scale, we present the analysis in some detail. Implications for the acceleration of cosmic rays depend on the details of the source modeling. We discuss some important aspects in this paper., 9 pages, 6 figures, accepted for publication in Astronomy & Astrophysics

12. Scalar damage model for concrete without explicit evolution law

Author

Ožbolt, Joško, Ananiev, Sergej, and N. Bicanic, R. de Borst, H. Mang, G. Meschke

Subjects
Concrete, damage, finite elements
Abstract

Based on the fact that for an isotropic material model the elastic predictor and the projected stress tensors have the same eigenvectors, it is shown that the scalar damage can be obtained directly from the projection algorithm. This eliminates the difficulty of a proper definition of equivalent strain which serves as a driving force for evolution of damage in concrete. Moreover, if eigenvectors are known it is not more nec-essary to use invariants of the stress tensor for the formulation of loading surface. In the present model the loading surface is represented in the polynomial form. This has two advantages: (i) it automatically fulfils C1 continuity and (ii) plane stress formulation is achieved by simply setting the third stress to zero. The perform-ance of the model is illustrated on example of a mixed-mode fracture of concrete. It is shown that for the pre-sent example the model prediction strongly depends on the choice of the stress degradation law.

Published
2003

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