Search

Your search keyword '"Bresciano, E."' showing total 22 results
Start Over Author "Bresciano, E." Database OpenAIRE
22 results on '"Bresciano, E."'

1. Studies on the Inhibitory Effects of Caffeoylquinic Acids on Monocyte Migration and Superoxide Ion Production

Author

Vuotto Ml, De Feo, Peluso G, Bresciano E, and De Simone F

Subjects
Molecular Sequence Data, Quinic Acid, Pharmaceutical Science, Inhibitory postsynaptic potential, Monocytes, Analytical Chemistry, chemistry.chemical_compound, Superoxides, Drug Discovery, medicine, Humans, Amino Acid Sequence, Cells, Cultured, Pharmacology, Plants, Medicinal, Tessaria integrifolia, Superoxide, Monocyte, Organic Chemistry, In vitro, N-Formylmethionine Leucyl-Phenylalanine, Chemotaxis, Leukocyte, medicine.anatomical_structure, Complementary and alternative medicine, chemistry, Biochemistry, Mikania cordifolia, Molecular Medicine
Abstract

Three caffeoylquinic acids, isolated from the Peruvian plants Tessaria integrifolia and Mikania cordifolia that are used medicinally as anti-inflammatory agents, were tested for their activities on monocyte migration and superoxide anion production. 3,5-Di-O-caffeoylquinic and 4,5-di-O-caffeoylquinic acids exhibited an appreciable anti-inflammatory activity in vitro, while the tricaffeoyl derivative was inactive.

Published
1995
Full Text
View/download PDF

3. Attivazione linfocitaria, apoptosi e immunoregolazione nella leucemia linfatica cronica a cellule B

Author

LUCIVERO, Giacomo, DE FANIS U, DALLA MORA, Liliana, ROMANO, Ciro Pasquale, CRAVERO R, GIUNTA, Riccardo, GUASTAFIERRO, Salvatore, PEZONE, Luciano, BRESCIANO E, MANCINO D, TIRELLI A., Lucivero, Giacomo, DE FANIS, U, DALLA MORA, Liliana, Romano, Ciro Pasquale, Cravero, R, Giunta, Riccardo, Guastafierro, Salvatore, Pezone, Luciano, Bresciano, E, Mancino, D, and Tirelli, A.

Published
2001

5. [Late onset immunodeficiency with hypo-IgG and hyper-IgM, T CD4+ lymphocytopenia and vitiligo]

Author

D'Addio F, Giunta R, Scarfiglieri D, De Fanis U, Liliana DALLA MORA, Pezone L, Bresciano E, Mancino D, Lucivero G, D'Addio, F, Giunta, Riccardo, Scarfiglieri, D, DE FANIS, U, DALLA MORA, Liliana, Pezone, Luciano, Bresciano, E, Mancino, D, and Lucivero, Giacomo

Subjects
Adult, Male, Immunoglobulin M, Vitiligo, Humans, IgG Deficiency, T-Lymphocytopenia, Idiopathic CD4-Positive
Abstract

The Authors report the clinical case of a patient with a deficit of humoral immunity who developed infections since puberty. The serum levels of IgG and IgA decreased progressively in the fourth decade of life, while serum IgM increased. Moreover, the patient developed a marked CD4+ T lymphocytopenia and a meager B lymphocytopenia, vitiligo, positivity for anti-SSA/Ro autoantibodies and granulomatous phlogosis of the knee. The heterogeneity of the clinical and laboratory data suggests that this patient might present an overlap immunodeficiency syndrome with some of the clinical and immunological features typical of the hyper-IgM syndrome (in the X-linked or autosomal forms) and others that can be referred to a nosologically distinct humoral immunodeficiency such as the common variable immunodeficiency.

Published
2001

6. Le molecole di cooperazione tra T e B linfociti nelle malattie linfoproliferative croniche: ruolo nella regolazione della proliferazione, dell’apoptosi e dell’accumulo linfocitario

Author

DE FANIS U, IACCARINO S, PEZONE, Luciano, TIRELLI A, GIUNTA, Riccardo, BRESCIANO E, MANCINO D, LUCIVERO, Giacomo, DALLA MORA, Liliana, Lucivero, Giacomo, DE FANIS, U, DALLA MORA, Liliana, Iaccarino, S, Pezone, Luciano, Tirelli, A, Giunta, Riccardo, Bresciano, E, Mancino, D., and Mancino, D

Published
1999

10. Immunità e invecchiamento

Author

LUCIVERO, Giacomo, TIRELLI A, COPPOLA L, BRESCIANO E, GAMBARDELLA, Antonio, GIUNTA, Riccardo, VARRICCHIO M., DALLA MORA, Liliana, Lucivero, Giacomo, Tirelli, A, Coppola, L, Bresciano, E, DALLA MORA, Liliana, Gambardella, Antonio, Giunta, Riccardo, and Varricchio, M.

Published
1997

19. Differences in constitutive and activation-induced expression of CD69 and CD95 between normal and chronic lymphocytic leukemia B cells

Author

De Fanis U, Romano C, Liliana DALLA MORA, Sellitto A, Guastafierro S, Tirelli A, Bresciano E, Giunta R, Lucivero G, DE FANIS, U, Romano, Ciro Pasquale, DALLA MORA, Liliana, Sellitto, A, Guastafierro, Salvatore, Tirelli, Armando, Bresciano, E, Giunta, Riccardo, and Lucivero, Giacomo

Subjects
Antigens, Differentiation, T-Lymphocyte, Male, B-Lymphocytes, Ionophores, Ionomycin, Apoptosis, Lymphocyte Activation, Leukemia, Lymphocytic, Chronic, B-Cell, Immunophenotyping, Up-Regulation, Antigens, Differentiation, B-Lymphocyte, Pokeweed Mitogens, Antigens, CD, Case-Control Studies, Carcinogens, Humans, Tetradecanoylphorbol Acetate, Female, Lectins, C-Type, fas Receptor, Phytohemagglutinins, Aged
Abstract

B-cell chronic lymphocytic leukemia (B-CLL) is characterized by a sustained accumulation of long-lived and well-differentiated B lymphocytes in lymphoid tissues, peripheral blood and bone marrow. Although the pathogenesis of this disease is not entirely understood, altered apoptosis is believed to play a relevant role in B-CLL. In this study, we compared the expression of CD95, the best characterized surface molecule involved in triggering the apoptotic machinery, on normal and CLL B cells before and after in vitro activation with polyclonal stimulators. Cell activation was monitored by verifying the induced expression of the early activation antigen CD69. Freshly analyzed CLL B cells showed significantly lower levels of CD95 than normal B cells. Moreover, following in vitro culture with phorbol 12-myristate 13-acetate (PMA) + ionomycin, phytohemagglutinin, or pokeweed mitogen, CLL B cells failed to upregulate CD95 expression as efficiently as normal B cells. Impairment of CD95 upregulation was mainly observed following PMA + ionomycin treatment. In contrast, CLL B cells were shown to express CD69 as well as normal B cells, regardless of the activator used, indicating that CLL B cells retain the ability to respond to activating stimuli but are unable to efficiently implement the CD95-mediated activation-induced cell death (AICD) program. In conclusion, these results suggest that prolonged survival of CLL B cells may be contributed to by alterations in AICD mechanisms.

21. Functional characteristics of cord blood T lymphocytes after lectin and anti-CD3 stimulation

Author

E Bresciano, L. Pezone, L Dalla Mora, G. Lucivero, D. Mancino, M. P. Loria, Lucivero, Giacomo, DALLA MORA, Liliana, Bresciano, E, Loria, Mp, Pezone, Luciano, and Mancino, D.

Subjects
Adult, CD3 Complex, T-Lymphocytes, Clinical Biochemistry, Antibodies, Monoclonal, Receptors, Interleukin-2, T lymphocyte, Biology, CD38, Fetal Blood, TCIRG1, Immune system, Antigen, Antigens, CD, T-Lymphocyte Subsets, Concanavalin A, Cord blood, Receptors, Transferrin, Immunology, biology.protein, Humans, IL-2 receptor, Phytohemagglutinins, Cell Division
Abstract

Newborns are more susceptible than adults to infections, which suggests a relative immaturity of the immune system early after birth. Cord blood T cells differ significantly both in surface phenotype and function from adult T cells. We examined the proliferation and expression of activation molecules by lymphocytes isolated from umbilical cord blood or peripheral blood of adults. The lymphocytes were cultured for 5 days in the presence of phytohemagglutinin, concanavalin A, or anti-CD3 monoclonal antibody. Cord blood T cells expressed the CD45RA molecule, while a low proportion expressed the RO isoform, a marker of primed or activated lymphocytes. Furthermore, more than 95% of neonatal lymphocytes bear the CD38 molecule, but do not express the CD57 molecule. After stimulation by phytohemagglutinin or concanavalin A, the lymphocytes from newborns were activated and proliferated as efficiently as adult T cells. Anti-CD3 did not cause neonatal lymphocytes to proliferate, but these cells expressed activation molecules, such as HLA-DR antigens and the receptor for interleukin-2 and transferrin. The relevance of these findings to tolerance induction in immature cord blood T cells is discussed.

Published
1996
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results