1. Study of a Prototype VP-PET Imaging System Based on highly Pixelated CdZnTe Detectors
- Author
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Ye, Zheng-Qian, Li, Ying-Guo, Wang, Tian-Quan, Fan, Ya-Ming, Yin, Yong-Zhi, and Chen, Xi-Meng
- Subjects
Physics - Instrumentation and Detectors ,FOS: Physical sciences ,Medical Physics (physics.med-ph) ,Instrumentation and Detectors (physics.ins-det) ,Physics - Medical Physics - Abstract
We are investigating a prototype virtual pinhole positron emission tomography (VP-PET) system for small animal imaging applications. The PET detector modules were made up of 1.3 mm lutetium-yttrium oxyorthosilicate (LYSO) arrays, and the insert detectors consists of 0.6 mm pixelated Cadmium Zinc Telluride (CdZnTe). To validate the imaging experiment, we conducted a Monte Carlo simulation for the VP-PET system in Geant4 Application for Emission Tomography (GATE). For a point source of Na-22 with 0.5 mm diameter, the filtered back-projection (FBP) algorithm reconstructed PET image shows a resolution of 0.7 mm full-width-at-half-maximum (FWHM). The system sensitivity is 0.46 cps/kBq at the center of field view (CFOV) of the PET system with a source activity of 0.925 MBq and an energy resolution of 350-650 keV. A rod source phantom and a Derenzo phantom with F-18 were also simulated to investigate the PET imaging capability. GATE simulation indicated that two point sources with 0.5 mm diameter 2 mm apart could be clearly separated using 0.6 mm pixelated CdZnTe detectors as insert devices in a VP-PET system., 13 pages, 7 figures
- Published
- 2018