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Supplemental material, sj-docx-1-cat-10.1177_10760296231171081 for Standard-Intensity Versus Low-Intensity Anticoagulation with Warfarin in Asian Patients with Atrial Fibrillation: A Multi-Center, Randomized Controlled Trial by Jeong Gwan Cho, Ki Hong Lee, Yoo Ri Kim, Sunah Kim, Jisoo Gwak, Eunbit Cho, Yourim Sin, Seung Yong Shin, Hyung Wook Park, Jum Suk Ko, Nam Ho Kim, Yae Min Park, Jung Myung Lee, Nam Sik Yoon, Sung Soo Kim, Jun Hyung Kim and Dong Min Kim in Clinical and Applied Thrombosis/Hemostasis

Background High-risk percutaneous coronary interventions (PCIs) are associated with a high complication rate, a low procedural success rate and a high restenosis rate, especially in diabetics. We sought to determine whether abciximab (ReoPro®) therapy affects long-term clinical outcomes of Korean patients with diabetes undergoing high-risk PCI. Methods: One hundred and nineteen patients with 152 lesion sites were administered ReoPro® among 2,231 patients who underwent PCI at Chonnam National University Hospital from March 1999 to Feb 2001. These 119 patients were divided into two groups, 30 were allocated to a diabetic group (Group I, 57.7±8.2 years, 22 male), and 89 to a non-diabetic group (Group II, 59.6+10.8 years, 68 male). Early and long-term clinical outcomes after PCI were analyzed. Results: In terms of clinical diagnosis, the number of acute myocardial infarctions in Group I was 25 (83.3%) and 76 in Group II (85.4%). As for risk factors, target artery lesions, and ACC/AHA types, no differences were found between the two groups. The number of patients with total occlusion was 21 (55.3%) and 62 (53.9%), and the number with a thrombus-containing lesion was 28 (93.3%) and 88 (98.9%) in Groups I and II, respectively. The procedure was successful in 27 (90.0%) in Group I, and in 80 (89.9%) in Group II, and no differences were evident between the two groups in terms of bleeding complications. No major adverse cardiac events (MACE), including myocardial infarction, repeat revascularization or cardiac death, were observed in Group I, but 8 cases of MACE occurred in Group II during hospitalization. Clinical follow-up was performed in 116 patients (97.5%) over 18.5 ± 6.7 (5–28) months. The number of overall MACEs was 10 (3.3%) in Group I and 14 (15.7%) in Group II (p=0.038). Conclusion: ReoPro® used in high-risk PCI in diabetics was effective in terms of early clinical outcomes, but its long-term clinical benefits were not proven.

A 56-year-old man got admitted as he was suffering from dizziness for 3 days. Electrocardiogram (ECG) showed complete atrioventricular (AV) block with ventricular rhythm of 35/min. We found that he had no inferior vena cava (IVC) which drained into right atrium in the middle of temporary pacing lead insertion. Venous drainage into superior vena cava from dilated azygos vein was identified after venogram. Echocardiogram revealed a congenitally corrected transposition of the great arteries (CCTGA). Chest computed tomography (CT) angiogram revealed AV and ventriculoarterial discordance with reversed ventricles and interrupted IVC with azygos continuation. DDD pacemaker was implanted via left axillary vein without any problem.