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Chondrosarkome sind die häufigsten aller primären Sternumtumore. Eine radikale R0-Resektion stellt die einzige kurative Therapieoption dar. Totale oder partielle Sternumresektionen sollten mittels eines gestielten, gut vaskularisierten Hautmuskellappens gedeckt werden. Ein transossär [zum vollständigen Text gelangen Sie über die oben angegebene URL], 49. Jahrestagung der Deutschen Gesellschaft der Plastischen, Rekonstruktiven und Ästhetischen Chirurgen (DGPRÄC), 23. Jahrestagung der Vereinigung der Deutschen Ästhetisch-Plastischen Chirurgen (VDÄPC)

Treatment of cycloheptanone or 2-cycloheptylidenecycloheptanone with concentrated sulfuric acid, leads to self-condensation accompanied by intramolecular rearrangement and cyclization to give substituted tetrahydrofurans, viz. 2-methyl-2, 3-cyclohexano-4, 5-cyclohepteno-(Δ 5)-2, 3, 4, 5-tetrahydrofuran and 2-methyl-2, 3-cyclohexano-5-hydroxy-4, 5-cycloheptano-2, 3, 4, 5-tetrahydrofuran. Self-condensation of ketones with 6-membered rings under the action of concentrated sulfuric acid, proceeding via carbonium ions, and accompanied by contraction to a 5-membered ring, is also characteristic of cycloheptanone, the 7-membered ring of which isomerizes to a 6-membered one. © 1968 The Faraday Press, Inc.

In reaction with concentrated sulfuric acid 2-, 3-, and 4-methylcyclohexanones undergo autocondensation and simultaneous intramolecular cyclization with formation of furan compounds. © 1967 Consultants Bureau.

Theophylline concentrations in serum and in saliva obtained without and with stimulation (dil. citric acid) of 20 patients in the age range of 5-19 years on a long term theophylline therapy were simultaneously assessed within 6 hours after drug intake; at the same time several parameters of the lung function were taken. The theophylline concentration measurements were performed gaschromatographically. The saliva concentrations obtained without stimulation very strongly correlated with the serum concentrations (r=0,98; mean deviation from the regression line 0,70/ug/ml). The saliva concentrations obtained with stimulation revealed a significantly weaker correlation with the serum concentrations (r=0,82). A dependence of the concentrations from the salivation rate (m1/2 minutes) could be identified (r=0,66) in the saliva obtained with as well as in that obtained without stimulation; this dependence exists both intra- and interindividually. Reliability and evidence of the saliva concentrations obtained without stimulation can be further increased by measurement of the secreted saliva volume per period of time.