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107 results on '"Ferrone Marco"'

1. RENASCENT II: First in Human Evaluation of a Novel Sirolimus-Eluting Ultra-High Molecular Weight APTITUDE® Bioresorbable Scaffold: 9-and 24-Months Imaging and Clinical Results

Author

Chieffo, Alaide, Khawaja, Saud Ahmed, Latib, Azeem, Vesga, Boris, Moncada, Miguel, Delgado, Juan A, Fonseca, Jaime, Testa, Luca, Esposito, Giovanni, Ferrone, Marco, Cortese, Bernardo, Maehara, Akiko, Granada, Juan F, Colombo, Antonio, Montorfano, Matteo, Hernandez, Hector, Arana, Camilo, Dager, Antonio, Bedogni, Francesco, Stabile, Eugenio, De Benedictis, Mauro, Meliga, Emanuele, Tarantini, Giuseppe, Antoniucci, David, La Manna, Alessio, Tamburino, Corrado, Chieffo, Alaide, Khawaja, Saud Ahmed, Latib, Azeem, Vesga, Bori, Moncada, Miguel, Delgado, Juan A, Fonseca, Jaime, Testa, Luca, Esposito, Giovanni, Ferrone, Marco, Cortese, Bernardo, Maehara, Akiko, Granada, Juan F, Colombo, Antonio, Montorfano, Matteo, Hernandez, Hector, Arana, Camilo, Dager, Antonio, Bedogni, Francesco, Stabile, Eugenio, De Benedictis, Mauro, Meliga, Emanuele, Tarantini, Giuseppe, Antoniucci, David, La Manna, Alessio, and Tamburino, Corrado

Abstract

The novel sirolimus-eluting ultra-high molecular weight 115-microns strut thickness APTITUDE® Bioreabsorbable vascular scaffold (BRS) (Amaranth Medical Inc., Mountain View, CA) displays higher mechanical strength, expansion capabilities and resistance to fracture compared to clinically available BRS technologies. RENASCENT II is a prospective, multi-center first-in-human clinical study to evaluate the clinical performance of the APTITUDE® BRS in the treatment of single de novo coronary lesions among patients undergoing percutaneous coronary intervention.

Published
2020

2. Immunohistochemistry for Histone H3G34W and H3K36M Is Highly Specific for Giant Cell Tumor of Bone and Chondroblastoma, Respectively, in FNA and Core Needle Biopsy

Author

Schaefer, Inga-Marie, Fletcher, Jonathan A., Petur Nielsen, G., Shih, Angela R., Ferrone, Marco L., Hornick, Jason L., and Qian, Xiaohua

Subjects
Adult, Aged, 80 and over, Giant Cell Tumor of Bone, Male, Adolescent, Biopsy, Fine-Needle, DNA Mutational Analysis, Antibodies, Monoclonal, Chondroblastoma, Bone Neoplasms, Middle Aged, Prognosis, Immunohistochemistry, Article, Histones, Young Adult, Mutation, Biomarkers, Tumor, Humans, Female, Biopsy, Large-Core Needle, Aged, Follow-Up Studies
Abstract

Diagnosing giant cell-rich bone tumors can be challenging on limited biopsies. H3 histone family member 3A (H3F3A) (G34W/V/R/L) mutations are present in the majority of giant cell tumors (GCTs) of bone and H3 histone family member 3B (H3F3B) (K36M) mutations are present in nearly all chondroblastomas, but are absent in histologic mimics. Mutation-specific immunohistochemistry (IHC) is highly specific for GCT and chondroblastoma in surgical excisions. The objective of the current study was to validate H3G34W and H3K36M IHC in the diagnosis of giant cell-rich bone tumors on fine-needle aspiration and core needle biopsy specimens.IHC was performed using monoclonal antibodies against histone H3.3 G34W and K36M in GCTs of bone (26 cases, including 2 malignant cases), GCT of Paget disease (1 case), chondroblastoma (8 cases), aneurysmal bone cyst (7 cases), and osteosarcoma (13 cases) with available fine-needle aspiration and/or core needle biopsy specimens from 2 institutions. H3F3A and H3F3B Sanger sequencing was performed on all 4 H3G34W IHC-negative GCTs.IHC for H3G34W was positive in 22 of 26 GCTs (85%) and negative in all histologic mimics. IHC for H3K36M was positive in all 8 chondroblastomas and negative in all histologic mimics. IHC results were concordant between biopsy and surgical specimens in 152 of 158 samples (96%). Sequencing identified alternate H3F3A G34L and G34V mutations in 1 IHC-negative GCT each, but no mutation was found in the remaining 2 cases.H3G34W and H3K36M IHC is highly specific for GCT and chondroblastoma, respectively, among giant cell-rich bone tumors, and is useful for confirming the diagnosis in limited biopsies. The presence of alternate H3F3A mutations accounts for the H3G34W IHC negativity in a subset of GCT of bone cases. Cancer Cytopathol 2018. © 2018 American Cancer Society.

Published
2018

3. A comparison of questionnaires for assessing physical function in patients with lower extremity bone metastases

Author

Janssen, Stein J., Paulino Pereira, Nuno Rui, Raskin, Kevin A., Ferrone, Marco L., Hornicek, Francis J., van Dijk, C. Niek, Lozano-Calderón, Santiago A., Schwab, Joseph H., Other departments, and Orthopedic Surgery and Sports Medicine

Abstract

To assess, (i) the degree to which the: PROMIS Physical Function Cancer, PROMIS Neuro-QoL Mobility, Toronto Extremity Salvage Score (TESS), Lower Extremity Function Score (LEFS), and Musculoskeletal Tumor Society score (MSTS), measure physical function; (ii) differences in coverage and reliability; and (iii) difference in completion time. One hundred of 115 (87%) patients with lower extremity metastases participated in this prospective study. We used exploratory factor analysis-correlating questionnaires with an underlying trait-to assess if questionnaires measure the same. Coverage was assessed by floor and ceiling effect and reliability by the standard error of measurement (SEM). Completion time was compared using the Friedman test. All questionnaires measured the same concept; demonstrated by high correlations (>0.7). Floor effect was absent, while ceiling effect was present in all, but highest for the PROMIS Neuro-QoL Mobility (7%). The SEM was below the threshold-indicating reliability-over a wide range of ability levels for the PROMIS-Physical Function, TESS, and LEFS. Completion time differed between questionnaires (P

Published
2016

4. De-Activation of Mitogen-Activated Protein Kinases in Peripheral Blood Mononuclear Cells of Patients Undergoing Trans-Catheter Aortic Valve Implantation

Author

Franzone Anna, Cannavo Alessandro, Ferrone Marco, Stabile Eugenio, Pucciarelli Armando, Sorropago Giovanni, Lucchetti Vincenzo, Rubino Paolo, PERRINO, CINZIA, ESPOSITO, GIOVANNI, Franzone, Anna, Cannavo, Alessandro, Perrino, Cinzia, Ferrone, Marco, Stabile, Eugenio, Pucciarelli, Armando, Sorropago, Giovanni, Lucchetti, Vincenzo, Rubino, Paolo, and Esposito, Giovanni

Published
2011

5. Design, synthesis and anti flaviviridae activity of N6-, -O- and 5 O-substituted adenine nucleoside analogs

Author

ANGUSTI A, MANFREDINI S, DURINI E, CILIBERTI N, VERTUANI S, SOLAROLI N, LODDO R, SECCI B, VISIOLI A, SANNA T, COLLU G, PEZZULLO M, LA COLLA P., PRICL, SABRINA, FERRONE, MARCO, FERMEGLIA, MAURIZIO, Angusti, A, Manfredini, S, Durini, E, Ciliberti, N, Vertuani, S, Solaroli, N, Pricl, Sabrina, Ferrone, Marco, Fermeglia, Maurizio, Loddo, R, Secci, B, Visioli, A, Sanna, T, Collu, G, Pezzullo, M, and LA COLLA, P.

Published
2008

10. Nanocompositi: da micro a mesoscala

Author

SCOCCHI, GIULIO, POSOCCO, PAOLA, FERMEGLIA, MAURIZIO, FERRONE, MARCO, PRICL, SABRINA, Handgraaf JW, Fraajie JGEM, Scocchi, Giulio, Posocco, Paola, Fermeglia, Maurizio, Ferrone, Marco, Pricl, Sabrina, Handgraaf, Jw, and Fraajie, Jgem

Subjects
polymer nanocomposites, computer-assisted molecular simulation, Multiscale molecular modeling, polymer nanocomposite
Abstract

La prospettiva generale di questo lavoro consiste nell’integrazione completa di tutte le scale di simulazione ora disponibili, all’interno di una procedura gerarchica finalizzata a fornire un protocollo di simulazione efficiente e solido, idoneo alla progettazionendi PCN di interesse industriale e la previsione della loro performance finale.

Published
2007

11. Design, synthesis and preliminary in vitro and in silico antiviral activity of [4,7]phenantrolines and 1-oxo-1,4-dihydro-[4,7]phenantrolines against a single-stranded positive sense RNA genome viruses

Author

CARTA A, LORIGA M, PAGLIETTI G, SANNA T, IBBA C, LA COLLA P, LODDO R., FERRONE, MARCO, FERMEGLIA, MAURIZIO, PRICL, SABRINA, Carta, A, Loriga, M, Paglietti, G, Ferrone, Marco, Fermeglia, Maurizio, Pricl, Sabrina, Sanna, T, Ibba, C, LA COLLA, P, and Loddo, R.

Subjects
Antiviral Agents
Published
2007

13. Chasing the evaders. Design, synthesis, activity and molecular modelling of a new small molecule with activity against drug-resistant HIV-1-mutants

Author

Pricl, Sabrina, Ferrone, Marco, Posocco, Paola, Fermeglia, Maurizio, Sanna, G., Collu, G., La Colla, P., Loddo, R., Sias, A., Piras, S., Carta, A., Pricl, Sabrina, Ferrone, Marco, Posocco, Paola, Fermeglia, Maurizio, Sanna, G., Collu, G., La Colla, P., Loddo, R., Sias, A., Piras, S., and Carta, A.

Subjects
reverse transcriptase, hiv, Computer simulation
Published
2006

14. Functional analysis and molecular modelling show a preserved wild type activity of p53 C238Y

Author

Ferrone, Marco, Perrone, F, Tamborini, E, Paneni, Maria Silvia, Fermeglia, Maurizio, Suardi, S, Pastore, E, Delia, D, Pierotti, M. A., Pricl, Sabrina, Pilotti, S., Ferrone, Marco, Perrone, F, Tamborini, E, Paneni, Maria Silvia, Fermeglia, Maurizio, Suardi, S, Pastore, E, Delia, D, PIEROTTI M., A, Pricl, Sabrina, and Pilotti, S.

Subjects
molecular modeling
Published
2006

15. Many-Scale Simulation of ABS/PC Blends for the Automotive Industry

Author

FERMEGLIA, MAURIZIO, FERRONE, MARCO, PANENI, Maria Silvia, POSOCCO, PAOLA, Cosoli P., Venica R., Sinesi S., Martinelli L., Vincenzini P., Fermeglia, Maurizio, Ferrone, Marco, Cosoli, P., Paneni, Maria Silvia, Venica, R., Sinesi, S., Posocco, Paola, and Martinelli, L.

Subjects
polymer blends, multiscale molecular modeling, polymer blend
Published
2006

16. Of life and Death: Chronic Myeloid Leukemia and the Bcr-Abl/Imatinib Paradigm

Author

FERRONE, MARCO, FERMEGLIA, MAURIZIO, PANENI, Maria Silvia, PRICL, SABRINA, Pierotti M. A., Pilotti S., Tamborini E., Joseph T. Golab, Clare McCabe, Ferrone, Marco, Fermeglia, Maurizio, Paneni, Maria Silvia, Pierotti, M. A., Pilotti, S., Tamborini, E., and Pricl, Sabrina

Subjects
chronic myeloid leukemia
Published
2006

17. Angels and demons of the guardian of the genome. A coupled modeling-biochemical study of p53 mutants in ovarian cancer

Author

PRICL, SABRINA, FERRONE, MARCO, PANENI, Maria Silvia, FERMEGLIA, MAURIZIO, Cosoli P., Perrone F., Da Riva L., Tamborini E., Suardi S., Pierotti M. P., Pilotti S., AACR, Pricl, Sabrina, Ferrone, Marco, Paneni, Maria Silvia, Cosoli, P., Fermeglia, Maurizio, Perrone, F., Da Riva, L., Tamborini, E., Suardi, S., Pierotti, M. P., and Pilotti, S.

Subjects
p53
Published
2006

18. Delivered to Perfection at Nanoscale. A Coupled Multiscale Simulation/Experimental Investigation of Protein Release from Nanochannel Delivery Systems

Author

FERMEGLIA, MAURIZIO, FERRONE, MARCO, PANENI, Maria Silvia, PRICL, SABRINA, Cosoli P., Cosentino C., Amato F., Cheng M. M. C., Walczak R., Ferrari M., Joseph T. Golab, Clare McCabe, Fermeglia, Maurizio, Ferrone, Marco, Cosoli, P., Paneni, Maria Silvia, Cosentino, C., Amato, F., Cheng, M. M. C., Walczak, R., Pricl, Sabrina, and Ferrari, M.

Subjects
Nanochannel Delivery Systems, Protein Release
Published
2006

19. Functional analyses and Molecular modeling of two c-Kit mutations responsible for Imatinib secondary resistance in GIST patients

Author

Tamborini, E, Pricl, Sabrina, Negri, T, Lagonigro, M. S., Miselli, F, Greco, A, Gronchi, A, Casali, P, Ferrone, Marco, Fermeglia, Maurizio, Pierotti, M. A., Pilotti, S., Tamborini, E, Pricl, Sabrina, Negri, T, LAGONIGRO M., S, Miselli, F, Greco, A, Gronchi, A, Casali, P, Ferrone, Marco, Fermeglia, Maurizio, PIEROTTI M., A, and Pilotti, S.

Subjects
drug resistance, imatinib, cancer target therapy, molecular simulations, molecular simulation
Abstract

Imatinib-acquired resistance related to the presence of secondary point mutations has become a frequent event in gastrointestinal stromal tumors. Here, transient transfection experiments with plasmids carrying two different KIT-acquired point mutations were performed along with immunoprecipitation of total protein extracts, derived from imatinib-treated and untreated cells. The molecular mechanics/Poisson Boltzmann surface area computational techniques were applied to study the interactions of the wild-type and mutated receptors with imatinib at the molecular level. Biochemical analyses showed KIT phosphorylation in cells transfected with vectors carrying the specific mutant genes. Imatinib treatment demonstrated that T670I was insensitive to the drug at all the applied concentrations, whereas V654A was inhibited by 6 lM of imatinib. The modeling of the mutated receptors revealed that both substitutions affect imatinib-binding site, but to a different extent: T670I substantially modifies the binding pocket, whereas V654A induces only relatively confined structural changes. We demonstrated that T670I and V654A cause indeed imatinib-acquired resistance and that the former is more resistant to imatinib than the latter. The application of molecular simulations allowed us to quantify the interactions between the mutated receptors and imatinib, and to propose a molecular rationale for this type of drug resistance.

Published
2006

20. A new twist for an old song. The DABO story revisited

Author

Pricl, Sabrina, Ferrone, Marco, Posocco, Paola, Pavan, G. M., Fermeglia, Maurizio, La Colla, P., Loddo, R., Pricl, Sabrina, Ferrone, Marco, Posocco, Paola, Pavan, G. M., Fermeglia, Maurizio, La Colla, P., and Loddo, R.

Subjects
hiv, reverse transcriptase, computer simulation
Published
2006

21. Take a walk on the nano side: structural and energetical analysis of ATP-binding pocket mutations of the cardiac beta-myosin heavy chain implicated in familial hypertrophic cardiomyopathy

Author

Cosoli, P., Ferrone, Marco, Paneni, Maria Silvia, Fermeglia, Maurizio, Pricl, Sabrina, Mason M., Fantechi S., Tomellini R., Cosoli, P., Ferrone, Marco, Paneni, Maria Silvia, Fermeglia, Maurizio, and Pricl, Sabrina

Subjects
Myosin, computer simulation, computer simulations, Myosins, mutations
Published
2005

23. T670X kit mutations in gastrointestinal stromal tumors: making sense of missense

Author

Pricl, Sabrina, Ferrone, Marco, Paneni, Maria Silvia, Fermeglia, Maurizio, Tamborini, E, Negri, T, Lagonigro, M. S., Miselli, F, Greco, A, Pierotti, M. A., Pilotti, S., Pricl, Sabrina, Ferrone, Marco, Paneni, Maria Silvia, Fermeglia, Maurizio, Tamborini, E, Negri, T, LAGONIGRO M., S, Miselli, F, Greco, A, PIEROTTI M., A, and Pilotti, S.

Subjects
gastrointestinal stromal tumors
Published
2005

26. Diffusion of proteins in nanochannels. A many-scale simulation approach

Author

FERRONE, MARCO, FERMEGLIA, MAURIZIO, PRICL, SABRINA, Cosentino C., Amato F., Ferrari M., Mason M., Fantechi S., Tomellini R., Ferrone, Marco, Fermeglia, Maurizio, Pricl, Sabrina, Cosentino, C., Amato, F., and Ferrari, M.

Subjects
Multiscale molecular modeling, protein release, nanochannels
Published
2005

27. Three-dimensional Pharmacophore Modeling of Hindered Nucleoside Analogs (HNAs) as Inhibitors of the Hepatitis C virus NS5B Polymerase

Author

Ferrone, Marco, Pricl, Sabrina, Fermeglia, Maurizio, Paneni, Maria Silvia, Angusti, A., Ciliberti, N., Buzzoni, L., Durini, E., Vertuani, S., Manfredini, S., Loddo, R., La Colla, P., Ferrone, Marco, Pricl, Sabrina, Fermeglia, Maurizio, Paneni, Maria Silvia, Angusti, A., Ciliberti, N., Buzzoni, L., Durini, E., Vertuani, S., Manfredini, S., Loddo, R., and La Colla, P.

Subjects
HCV, computer-assisted drug design
Published
2005

28. Upgrading block co-polymers from post industrial rejects: a multiscale simulation approach

Author

Fermeglia, Maurizio, Cosoli, P., Ferrone, Marco, Paneni, Maria Silvia, Pricl, Sabrina, Martinelli, L., Sinesi, S., Candus, M., J. Kenny, Fermeglia, Maurizio, Cosoli, P., Ferrone, Marco, Paneni, Maria Silvia, Pricl, Sabrina, Martinelli, L., Sinesi, S., and Candus, M.

Subjects
Nanotechnology, computer multiscale modeling, Nanocomposites, Nanotechnology, computer multiscale modeling, Nanocomposites
Published
2005

30. Non-nucleoside anti-Flaviviridae agents from different molecular classes: a jointed experimental/modeling effort

Author

Angusti A., Auzzas L., Boido V., Canu C., Carta A., Ciliberti N., Loddo R., La Colla P., Loriga M., Manfredini S., Mazzei M., Nieddu E., Paglietti G., Paneni M. S., Rassu G., Sparatore F., Tasso B., Vitale G., FERRONE, MARCO, PRICL, SABRINA, Angusti, A., Auzzas, L., Boido, V., Canu, C., Carta, A., Ciliberti, N., Ferrone, Marco, Loddo, R., La Colla, P., Loriga, M., Manfredini, S., Mazzei, M., Nieddu, E., Paglietti, G., Paneni, M. S., Pricl, Sabrina, Rassu, G., Sparatore, F., Tasso, B., and Vitale, G.

Subjects
HCV, RdRp inhibitors, computer-assisted drug design, RdRp inhibitor
Published
2005

32. 'Fatty' nucleoside analogs as HCV NS5b inhibitors

Author

PRICL, SABRINA, FERMEGLIA, MAURIZIO, FERRONE, MARCO, COSLANICH, ALESSANDRO, PANENI, Maria Silvia, Manfredini S., Angusti A., La Colla P., Mura M., AIChE, Pricl, Sabrina, Fermeglia, Maurizio, Ferrone, Marco, Coslanich, Alessandro, Paneni, Maria Silvia, Manfredini, S., Angusti, A., La Colla, P., and Mura, M.

Subjects
HCV, RdRp inhibitors, computer-assisted drug design, RdRp inhibitor
Published
2004

33. Genotype-phenotype correlations of myosin mutations: a molecular simulation study

Author

Paneni, Maria Silvia, Ferrone, Marco, Pricl, Sabrina, Carniel, E., Miertus, S., Frecer, V., Mestroni, L., Titomanlio G., Paneni, Maria Silvia, Ferrone, Marco, Pricl, Sabrina, Carniel, E., Miertus, S., Frecer, V., and Mestroni, L.

Subjects
Myosins: genetics, mutations, computer simulations, mutation, genetic [Myosins]
Published
2004

34. Upgrading polymeric materials from post industrial rejects: a multiscale simulation approach

Author

Coslanich, Alessandro, Fermeglia, Maurizio, Ferrone, Marco, Pricl, Sabrina, Paneni, Maria Silvia, Martinelli, L., Sinesi, S., Candus, M., AIChE, Coslanich, Alessandro, Fermeglia, Maurizio, Ferrone, Marco, Pricl, Sabrina, Paneni, Maria Silvia, Martinelli, L., Sinesi, S., and Candus, M.

Subjects
polymer nanocomposites, polymer nanocomposite, recyclable plastics, multiscale molecular modeling
Published
2004

35. Diblock copolymers for the automotive industry: the mesoscopic approach

Author

Coslanich, Alessandro, Fermeglia, Maurizio, Ferrone, Marco, Paneni, Maria Silvia, Pricl, Sabrina, Martinelli, L., Sinesi, S., Vincenzini P., Lami A., Coslanich, Alessandro, Fermeglia, Maurizio, Ferrone, Marco, Paneni, Maria Silvia, Pricl, Sabrina, Martinelli, L., and Sinesi, S.

Subjects
Multiscale molecular modeling, diblock copolymers, diblock copolymer
Published
2004

38. Hindered Nucleoside Analogs (HNA) as Antiflaviviridae Agents

Author

Manfredini, S., Angusti, A., Veronese, A. C., Durini, E., Vertuani, S., Nalin, F., Solaroli, N., Ferrone, Marco, Pricl, Sabrina, Mura, M., Piano, M. A., Poddesu, B., Cadeddu, A., LA COLLA, P., Loddo, R., Manfredini, S., Angusti, A., VERONESE A., C, Durini, E., Vertuani, S., Nalin, F., Solaroli, N., Ferrone, Marco, Pricl, Sabrina, Mura, M., PIANO M., A, Poddesu, B., Cadeddu, A., LA COLLA, P., and Loddo, R.

Published
2004

39. Prediction fo HIV-1 resistance to NNRITs: a computer-aided molecular-based rationale

Author

Pricl, Sabrina, Coslanich, Alessandro, Fermeglia, Maurizio, Ferrone, Marco, Paneni, Maria Silvia, Loddo, R., Cabizza, A., Sanna, G., Murreddu, M., La Colla, P., Pricl, Sabrina, Coslanich, Alessandro, Fermeglia, Maurizio, Ferrone, Marco, Paneni, Maria Silvia, Loddo, R., Cabizza, A., Sanna, G., Murreddu, M., and La Colla, P.

Subjects
antiviral drug design, HIV, computer-assisted drug design
Published
2004

40. Analogies in imatinib-resistant threonine-to-isoleucine mutation in bcr-abl, kit and pdgfra: a combined experimental/computational approach

Author

Pricl, Sabrina, Coslanich, Alessandro, Fermeglia, Maurizio, Ferro, M., Ferrone, Marco, Paneni, Maria Silvia, Tamborini, E., Negri, T., Lagonigro, S., Greco, A., Gabanti, E., Pierotti, M. A., Pilotti, S., Pricl, Sabrina, Coslanich, Alessandro, Fermeglia, Maurizio, Ferro, M., Ferrone, Marco, Paneni, Maria Silvia, Tamborini, E., Negri, T., Lagonigro, S., Greco, A., Gabanti, E., Pierotti, M. A., and Pilotti, S.

Subjects
cancer mutations, c-Kit, cancer mutation, computer simulations
Published
2004

42. Design, synthesis and characterization of folate-cyclodextrin bioconjugate for active drug delivery: results from combined computational and experimental efforts

Author

PRICL, SABRINA, FERMEGLIA, MAURIZIO, COSLANICH, ALESSANDRO, FERRONE, MARCO, PANENI, Maria Silvia, Caliceti P., Salmaso S., Semenzato S., AIChE, Pricl, Sabrina, Fermeglia, Maurizio, Coslanich, Alessandro, Ferrone, Marco, Paneni, Maria Silvia, Caliceti, P., Salmaso, S., and Semenzato, S.

Subjects
cyclodextrins, cyclodextrin, drug delivery, nanovector, nanovectors, Computer simulation
Published
2004

43. Computer-assisted design of new, potential HCV inhibitors

Author

PRICL, SABRINA, FERMEGLIA, MAURIZIO, FERRONE, MARCO, Manfredini S., Angusti A., Di Santo R., Frecer V., Miertus S., James F. Ely, George Jackson, Pricl, Sabrina, Fermeglia, Maurizio, Ferrone, Marco, Manfredini, S., Angusti, A., Di Santo, R., Frecer, V., and Miertus, S.

Subjects
HCV inhibitors
Published
2003

44. A Tumor (GIST), a Mutated Gene (c-kit), and a Molecular Inhibitor (Imatinib): Insights from Computer Simulations

Author

Pricl, Sabrina, Coslanich, A., Fermeglia, Maurizio, Ferrone, Marco, Albertini, V., Bonadiman, L., Tamborini, E., Pierotti, M. A., Pilotti, S., AICHe, Pricl, Sabrina, Coslanich, A., Fermeglia, Maurizio, Ferrone, Marco, Albertini, V., Bonadiman, L., Tamborini, E., Pierotti, M. A., and Pilotti, S.

Subjects
computer simulations, Molecular Inhibitor, computer simulation
Published
2003

45. How the Angstrom modifies the nano: effect of point mutations on the nanodimensional structure of human TP53 point mutations

Author

Coslanich, Alessandro, Fermeglia, Maurizio, Ferrone, Marco, Pricl, Sabrina, Tamborini, E., Oggioni, M., Perrone, F., Pilotti, S., Delia, D., Pierotti, M. A., Fantechi S., Tomellini R., Coslanich, Alessandro, Fermeglia, Maurizio, Ferrone, Marco, Pricl, Sabrina, Tamborini, E., Oggioni, M., Perrone, F., Pilotti, S., Delia, D., and Pierotti, M. A.

Subjects
p53 tumor suppressor, mutation in cancer, molecular simulation
Published
2003

46. Design, synthesis and activity of phosphonoacetic acid (Ppa) ester and amide bioisosters of ribofuranosylnucleoside diphosphates as potential ribonucleotide reductase inhibitors

Author

Manfredini, S., Solaroli, N., Porcu, L., Durini, E., Angusti, A., Vertuani, S., Verri, A., Spadai, S., Focher, F., Ferrone, Marco, Pricl, S., DE CLERCQ, E., Balzarini, J., Manfredini, S., Solaroli, N., Porcu, L., Durini, E., Angusti, A., Vertuani, S., Verri, A., Spadai, S., Focher, F., Ferrone, Marco, Pricl, S., DE CLERCQ, E., and Balzarini, J.

Published
2003

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