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In der Pathogenese der Atherosklerose spielt der oxidative Stress, insbesondere die oxidative Modifikation von LDL-Cholesterin, eine bedeutende Rolle. Mehrere epidemiologische Studien konnten einen Zusammenhang zwischen der Einnahme von Antioxidanzien und einer verminderten kardiovaskulären Mortalität zeigen. In tierexperimentellen Studien wurde gezeigt, dass eine Supplementierung mit Antioxidanzien zu einer verminderten Progression der Atherosklerose führte. In kontrollierten, klinischen Studien am Menschen konnte jedoch für die Einnahme von Antioxidanzien kein Benefit in der Primär- und Sekundärprävention von kardiovaskulären Erkrankungen nachgewiesen werden. Eine Vitamin- bzw. Antioxidanzien-Supplementierung in präventiver oder therapeutischer Absicht kann daher zur Zeit nicht empfohlen werden.

The present work shows the fabrication of a printed RFID label using large-area printing processes, such as roto-screen and stencil printing, and the integration with advanced assembly methods of CMOS-based humidity and temperature sensors. The fabrication of the antenna and the PCB on flexible plastic substrates (i.e. polyethylene terephthalate - PET) was performed by means of roto-screen printing in combination with flash photonic sintering. This allows a high thermal transfer to the printed material, which is necessary for its sintering, while preserving the delicate polymeric substrate. Cost-effective and low temperature methods are also developed for the assembling of the components onto polymeric substrates. The electrical interconnections were stencil-printed with isotropic conductive adhesives by using laser-ablated stencil masks on polymer foils. Additionally, the label incorporates an RF remotely rechargeable thin film battery which is used for data logging. Finally, the roto-screen printing of copper oxide patterns and their reduction to copper by means of a Xenon flash photonic process is presented.

According to Eurocode 8 moderate to high dissipative behaviour of timber structures requires sufficient ductility of the critical regions. Earlier experiments on timber connections with slotted-in steel plates and laterally loaded common steel dowels rarely achieved high ductility values. Connections consisting of LVL-C members, doweltype fasteners with different post-elastic steel properties, full confinement of the timber member and measures to restrain the notch effect were investigated by means of monotonic and cyclic tests with regards to the displacement ductility. The measures taken proved to be effective in enhancing the plastic deformation capacity of the steel dowels to a large extent. However, a new aspect was observed: the constriction of the dowels in the contact area with the plate. The research results provided a better understanding of the factors influencing the behaviour of slotted-in steel plate connection.