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7 results on '"Ichioka T"'

3. Atomic spectroscopy and collisions using slow antiprotons

Author

Azuma, T, Bakos, J S, Bluhme, H, Charlton, M, Dörner, R, Eades, John, Fujiwara, M C, Funakoshi, R, Hayano, R S, Higaki, H, Hoekstra, R, Hori, Masaki, Horváth, D, Hyodo, T, Ichioka, T, Ishikawa, T, Iwasaki, M, Juhász, B, Kambara, T, Ketzer, B, Knudsen, H, Kojima, T, Komaki, K I, Kuga, T, Kumakura, M, Kuroda, M, Kuroki, K, McCullough, R W, Merrisson, J, Mikkelsen, U, Mohri, A, Morita, N, Møller, S P, Nakai, Y, Oshima, N, Rothard, H, Sakaguchi, J, Scheidenberger, C, Schmidt-Böcking, H, Slevin, J, Suzuki, K, Tanuma, H, Thompson, W R, Torii, H A, Uggerhøj, Erik, Ujvári, B, Ullrich, J, Wada, M, Widmann, E, Yamaguchi, H, Yamazaki, T, Yamazaki, Y, and Yoshiki-Franzén, K

Subjects
Detectors and Experimental Techniques
Published
2000

4. Alport's Hereditary Nephritis with the Nephrotic Syndrome

Author

Kaname Okada, Masuhide Miyao, Shoyoji Kagami, Koichiro Kawakami, Ichioka T, Tatsuo Shimokawa, and Ichiro Yano

Subjects
medicine.medical_specialty, Pathology, Kidney, medicine.diagnostic_test, urogenital system, business.industry, Glomerular basement membrane, urologic and male genital diseases, medicine.disease, medicine.anatomical_structure, Endocrinology, Mesangium, Internal medicine, Pediatrics, Perinatology and Child Health, Intramembranous ossification, Biopsy, medicine, Renal biopsy, business, Nephrotic syndrome, Nephritis
Abstract

Histopathological changes were studied in renal biopsy specimens from a ten-year-old boy diagnosed as having Alport's hereditary nephritis with the nephrotic syndrome. Biopsy specimens of the kidney showed mild hypercellularity with an increase of mesangial matrix, irregular thickening of the capillary walls in the glomeruli, and numerous clusters of interstitial foam cells by light microscopy. Granular deposits of IgG, IgM, C3 and fibrinogen were seen along the capillaries and partially in the mesangium by immunofluoroscopy. Ultrastructurally, the lesions had various abnormalities of the glomerular basement membrane, including splitting, thinning, disruption, reticulation and irregular thickening. The mesangial matrix was increased and intramembranous deposits were observed. Foam cells were seen among both tubular and interstitial cells.

Published
1980
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5. Cytidine 5'-diphosphate reductase and thymidine kinase activities in phytohemagglutinin-stimulated lymphocytes of normal subjects of various ages and patients with immunodeficiency

Author

Masuhide Miyao, Ichioka T, Yasuhiro Kuroda, Etsuo Naito, Eiji Takeda, T Watanabe, Michinori Ito, Hosoda T, and Sekiguchi T

Subjects
Adult, medicine.medical_specialty, Adolescent, Ribonucleoside Diphosphate Reductase, Lymphocyte, Reductase, Lymphocyte Activation, Thymidine Kinase, chemistry.chemical_compound, Internal medicine, Ribonucleotide Reductases, Medicine, Humans, CDP reductase activity, Lymphocytes, Phytohemagglutinins, Child, Nucleotide salvage, Cytidine diphosphate, Aged, business.industry, Immunologic Deficiency Syndromes, Infant, DNA, Middle Aged, Endocrinology, Ribonucleotide reductase, medicine.anatomical_structure, chemistry, Thymidine kinase, Child, Preschool, Pediatrics, Perinatology and Child Health, business, Thymidine
Abstract

The activities of CDP reductase and thymidine kinase in 10(6) to 5 X 10(6) phytohemagglutinin (PHA)-stimulated lymphocytes isolated from 2 to 5 ml of peripheral blood of individual subjects were measured. The activities of CDP reductase (pmol/h/10(7) cells) and thymidine kinase (nmol/h/10(7) cells) were high in infants, 698 +/- 307 and 64.2 +/- 20.2, constant in subjects of 1-40 years old, 401 +/- 181 and 38.1 +/- 15.3, and low in persons of more than 80 years old, 121 +/- 113 and 22.3 +/- 17.8, respectively. The ratio of thymidine kinase to CDP reductase activity increased with age, indicating that dependency on the salvage pathway of DNA synthesis in lymphocytes increased with age. The activities of CDP reductase and thymidine kinase were reduced in patients with the hyperimmunoglobulin E syndrome, congenital cytomegalovirus infection, anhidrotic ectodermal dysplasia with hyperimmunoglobulin A, Bloom's syndrome, immunodeficiency with hyperimmunoglobulinemia, and Down's syndrome. The clinical symptoms of these diseases seem to be due to impaired DNA synthesis of PHA-stimulated lymphocytes, but the degrees of reduction of enzyme activities were generally greater than that of thymidine incorporation in these patients.

Published
1984

7. ASACUSA status report: ASACUSA progress during 2007 and plans for 2008

Author

Hayano, R. S., Andersen, H. H., Barna, D., Charlton, M., Corradini, M., Dax, A., Eades, J., Enomoto, Y., Higaki, H., Hori, M., Horvath, D., Hunniford, C. A., Ichioka, T., Imao, H., Juhasz, B., Kanai, Y., Knudsen, H., Kristiansen, P., Kuroda, N., Leali, M., Lodi-Rizzini, E., Malbrunot, C., Matsuda, Y., Mccullough, R. W., Moller, S. P., Mohri, A., Mozzanica, A., Nagata, Y., Ono, N., Pask, T., Pirkl, W., Andrea Puhm, Saito, H., Soter, A., Tokesi, K., Torii, H. A., Uggerhj, Ulrik Ingerslev, Varentsov, V. L., Venturelli, L., Widmann, E., Yamazaki, Y., Yoshida, Z., Zalan, P., and Zurlo, N.

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