Search

Your search keyword '"J. Buscher"' showing total 14 results
Start Over Author "J. Buscher" Database OpenAIRE
14 results on '"J. Buscher"'

2. VCP protects neurons from proteopathic seeding

Author

Jessica N. Patterson, Sara K. Pittman, Yuna M. Ayala, Jan Bieschke, Paul T. Kotzbauer, Mohamed Salman Kaleelurrrahuman, William J. Buscher, Dhruva Dhavale, Conrad C. Weihl, Yuanzi Sun, Albert A. Davis, Jiang Zhu, and Rachel L. French

Subjects
biology, Valosin-containing protein, Neurodegeneration, medicine.disease, Phenotype, Cell biology, Multisystem proteinopathy, law.invention, law, biology.protein, medicine, Suppressor, Seeding, Neuronal degeneration
Abstract

Background: Neuronal uptake and subsequent spread of proteopathic seeds, such as αS (alpha-synuclein), tau, and TDP-43, contribute to neurodegeneration and disease progression. The cellular machinery necessary for this process is poorly understood. Methods: Cas9 expressing αS FRET biosensors were transduced with a whole-genome guide RNA (gRNA) library, seeded with αS fibrils, and flow-sorted. Candidate genes protective against αS seeding were identified following gRNA sequencing of FRET+ and FRET- cell populations. Secondary validation of the high probability candidate suppressor VCP, utilized VCP inhibitors or gene knockdown in αS biosensors and primary neurons. In vivo validation was performed in VCP disease mutation mice following intrastriatal injection of αS seeds. TDP-43 seeding was performed in primary neurons from control or VCP mutant mice.Results: We devised a genome-wide CRISPR-Cas9 screen to identify suppressors of αS seeding. This approach identified Valosin Containing Protein (VCP) as a suppressor of αS seeding. Dominant mutations in VCP cause multisystem proteinopathy (MSP) a phenotypically and pathologically variable neurodegeneraive disease characterized by myopathy, motor neuron disease and dementia with TDP-43, αS and tau inclusions. VCP inhibition or MSP disease mutations increased αS seeding in cells and primary cultured neurons. This was similar to treatment with the lysosomal damaging agent, LLoMe or knockdown of the endolysosomal damage response associated VCP cofactor, UBXD1. Intrastriatal injection of αS seeds into VCP disease mice demonstrated enhanced seeding efficiency as compared with controls. Finally, this phenomenon was not specific to αS since VCP disease mutant expression increased TDP-43 seeding in neurons.Conclusion: VCP surveillance of permeabilized late endosomes protects neurons against the proteopathic spread of pathogenic protein aggregates. The spread of distinct aggregate species may dictate the pleiotropic phenotypes and pathologies in VCP associated MSP.

Published
2021
Full Text
View/download PDF

3. EV-Scale Sterile Neutrino Search Using Eight Years of Atmospheric Muon Neutrino Data from the IceCube Neutrino Observatory

Author

K. Tollefson, Albrecht Karle, U. Katz, R. S. Busse, G. H. Collin, Christopher Wiebusch, Kunal Deoskar, Thomas Ehrhardt, P. Schlunder, R. Hellauer, Spencer Axani, D. B. Fox, Kayla Leonard, R. Maunu, Alan Coleman, Sukeerthi Dharani, Francis Halzen, J. Merz, S. Hickford, R. Joppe, A. Wallace, Delia Tosi, Sebastian Baur, M. G. Aartsen, Carlos Arguelles, David Vannerom, I. Ansseau, Hermann Kolanoski, Juliana Stachurska, H. Dembinski, Stef Verpoest, Jessie Micallef, Matthias Vraeghe, George Japaridze, Roger Moore, Tim Ruhe, N. Kurahashi, Todor Stanev, C. Wendt, Ioana Codrina Maris, H. Bagherpour, Johan Wulff, Sebastian Böser, Olga Botner, J. Kim, Elisa Bernardini, A. Ludwig, Christoph Raab, Nadège Iovine, Timothyblake Watson, D. Heereman, Gisela Anton, M. Stamatikos, J. Bourbeau, K. Rawlins, G. de Wasseige, Won Nam Kang, V. Baum, Jenni Adams, D. Berley, G. C. Hill, H. Niederhausen, A. Steuer, C. Alispach, Bunheng Ty, Stephen L. Hauser, Raamis Hussain, Janet Conrad, B. Relethford, Jan Soedingrekso, Ralph Engel, Moritz Kellermann, Z. Griffith, Y. Makino, Seongjin In, R. Hoffmann, James Madsen, Konstancja Satalecka, Benjamin Bastian, Theo Glauch, Anastasia Maria Barbano, Saskia Philippen, F. Jonske, R. Cross, M. J. Larson, Lu Lu, T. Kittler, X. Bai, G. Neer, Alexander Fritz, A. Goldschmidt, D. van Eijk, Lenka Tomankova, Giovanni Renzi, D. Seckel, S. Fahey, Elisa Resconi, Alessio Porcelli, Claudio Kopper, Daniel Bindig, G. Krückl, Alejandro Diaz, C. Pérez de los Heros, E. O’Sullivan, Le Viet Nguyen, Wing Yan Ma, James DeLaunay, Marjon Moulai, R. G. Stokstad, K. Krings, M. Plum, P. B. Price, William Luszczak, M. Kauer, Suyong Choi, David Kappesser, S. E. Sanchez Herrera, Francesco Lucarelli, T. O. B. Schmidt, Tyce DeYoung, Chad Finley, Nathan Whitehorn, Immacolata Carmen Rea, Matti Jansson, D. Z. Besson, C. Walck, Thomas K. Gaisser, G. B. Yodh, A. Kyriacou, M. Silva, Najia Moureen Binte Amin, K.-H. Becker, Yiqian Xu, Qinrui Liu, J. Becker Tjus, T. Glüsenkamp, Subir Sarkar, Martina Karl, Matt Dunkman, Kendall Mahn, Christoph Tönnis, F. Huang, K. Meagher, Jochen M. Schneider, J. Stettner, T. R. Wood, Kurt Woschnagg, Paul Evenson, T. Palczewski, S. De Ridder, Y. L. Li, G. W. Sullivan, J. J. Beatty, Tianlu Yuan, Jeffrey Lazar, Chunfai Tung, James E. Braun, Alexander Trettin, E. Cheung, J. Werthebach, Thomas Stuttard, Mirco Hunnefeld, Marie Oehler, Alexander Sandrock, Elisa Lohfink, Thomas Meures, N. L. Strotjohann, M. A. Unland Elorrieta, M. Wallraff, Michael DuVernois, Benjamin Hokanson-Fasig, Felix Henningsen, Karl J. Clark, Simone Garrappa, Dmitry Chirkin, Sarah Pieper, D. Hebecker, Anatoli Fedynitch, K. Helbing, Chujie Chen, Dirk Ryckbosch, Joshua Hignight, M. Zöcklein, T. Grégoire, Timo Sturwald, J. C. Gallagher, Timo Karg, Gerald Przybylski, Federica Bradascio, Yang Lyu, Alexander Kappes, Alexander Burgman, M. Song, T. L. Carver, Paras Koundal, Mike Richman, Sarah Mancina, Paul Coppin, Anna Franckowiak, Tobias Hoinka, Vedant Basu, Steve Sclafani, F. McNally, A. R. Fazely, M. Usner, Grant Parker, R. Halliday, Stephan Meighen-Berger, K. D. de Vries, Gerrit Wrede, Andrea Turcati, J. van Santen, K. Hoshina, Glenn Spiczak, Thomas Huber, G. Momenté, Merlin Schaufel, A. Stößl, J. Kiryluk, K. Andeen, D. R. Nygren, Marek Kowalski, A. Weindl, Maryon Ahrens, Frederik Tenholt, R. Nagai, M. Medici, M. Rameez, Javier Gonzalez, Roxanne Turcotte, Alex Pizzuto, D. F. Cowen, Reina H. Maruyama, E. Pinat, N. Kulacz, U. Naumann, Martin Rongen, Ek Narayan Paudel, Allan Hallgren, Giorgio Maggi, K. Wiebe, A. Balagopal, Gary Binder, Zhedong Zhang, E. Unger, Simona Toscano, J. Auffenberg, Pablo Correa, Summer Blot, Brian Clark, C. De Clercq, P. Heix, K. Mase, P. Mallik, M. E. Huber, A. O'Murchadha, Marcos Santander, Ramesh Koirala, David A. Williams, L. Schumacher, Benedikt Riedel, S. Tilav, Max Renschler, D. Kang, D. J. Koskinen, Markus Ackermann, S. W. Barwick, L. Gerhardt, M. J. Weiss, E. Bourbeau, J. P. Yanez, Ben Smithers, Colin Turley, A. Olivas, S. Kopper, Spencer Griswold, I. Taboada, Michael O. Wolf, René Reimann, A. Haungs, M. Prado Rodriguez, Maria Tselengidou, D. Soldin, Nahee Park, Pranav Dave, K. Hultqvist, Darren Grant, E. Blaufuss, Mehmet Gunduz, Agnieszka Leszczyńska, R. C. Bay, M. Günder, Austin Schneider, Steven Robertson, Juan Carlos Diaz-Velez, Shefali Shefali, L. Classen, T. Stezelberger, Abdul Rehman, Carsten Rott, Y. Popovych, T. Kintscher, Frederik Hermann Lauber, Xianwu Xu, A. Terliuk, J. Sandroos, C. Bohm, Justin Lanfranchi, Christian Spiering, Justin Vandenbroucke, Abhishek Desai, S. C. Nowicki, Rasha Abbasi, B. J. Whelan, Jan Weldert, L. Halve, Philipp Eller, J. Felde, J. Buscher, D. Rysewyk Cantu, A. Obertacke Pollmann, J. L. Kelley, Markus Ahlers, Erik Ganster, Samvel Ter-Antonyan, Frank G. Schröder, J. Lünemann, N. van Eijndhoven, C. Haack, Emily Dvorak, Aaron Fienberg, Amirreza Raissi, Minjin Jeong, Chris Weaver, Stephanie Bron, C. J. Lozano Mariscal, H. Dujmovic, L. Rauch, S. Yoshida, Surujhdeo Seunarine, R. Snihur, Juanan Aguilar, Kael Hanson, A. Ishihara, Maximilian Meier, Paolo Desiati, Segev BenZvi, Spencer Klein, B. J. P. Jones, Andres Medina, Kara Hoffman, D. Mockler, Hershal Pandya, Daria Pankova, E. Friedman, Wolfgang Rhode, Robert Stein, L. Wills, P. Muth, R. Morse, Jakob Bottcher, T. Montaruli, Maximilian Karl Scharf, P. Peiffer, Ibrahim Safa, Damian Pieloth, Ali Kheirandish, W. Van Driessche, Jannes Brostean-Kaiser, M. U. Nisa, L. Köpke, T. Anderson, John Hardin, H. Schieler, Kirill Filimonov, Physics, Faculty of Sciences and Bioengineering Sciences, Vriendenkring VUB, and Elementary Particle Physics

Subjects
Sterile neutrino, Physics::Instrumentation and Detectors, General Physics and Astronomy, sterile [neutrino], 01 natural sciences, Cosmology, IceCube, High Energy Physics - Experiment, Subatomär fysik, High Energy Physics - Experiment (hep-ex), High Energy Physics - Phenomenology (hep-ph), Astronomi, astrofysik och kosmologi, Subatomic Physics, TOOL, Astronomy, Astrophysics and Cosmology, atmosphere [muon], Muon neutrino, Physics, oscillation [neutrino], Astrophysics::Instrumentation and Methods for Astrophysics, hep-ph, neutrino: sterile, mass difference [neutrino], ddc, muon: atmosphere, observatory, High Energy Physics - Phenomenology, Physique des particules élémentaires, signature, Particle physics, data analysis method, Scale (ratio), Astrophysics::High Energy Astrophysical Phenomena, neutrino: mass difference, FOS: Physical sciences, IceCube Neutrino Observatory, statistical analysis, 0103 physical sciences, OSCILLATIONS, ddc:530, 010306 general physics, hep-ex, ICE, High Energy Physics::Phenomenology, neutrino: mixing angle, CONVERSION, Physics and Astronomy, COSMOLOGY, High Energy Physics::Experiment, neutrino: oscillation, BAYESIAN-INFERENCE, mixing angle [neutrino], experimental results
Abstract

Physical review letters 125(14), 141801 (1-11) (2020). doi:10.1103/PhysRevLett.125.141801, The results of a 3+1 sterile neutrino search using eight years of data from the IceCube Neutrino Observatory are presented. A total of 305 735 muon neutrino events are analyzed in reconstructed energy-zenith space to test for signatures of a matter-enhanced oscillation that would occur given a sterile neutrino state with a mass-squared differences between 0.01 and 100 eV$^2$. The best-fit point is found to be at sin$^2$($2θ_{24}$)=0.10 and $Δm_{41}^2$=4.5 eV$^2$, which is consistent with the no sterile neutrino hypothesis with a $p$ value of 8.0%., Published by APS, College Park, Md.

Published
2020
Full Text
View/download PDF

4. IceCube-Gen2: The Window to the Extreme Universe

Author

J. Kim, A. Gartner, A. Obertacke Pollmann, B. Hoffmann, J. L. Kelley, Markus Ahlers, Jenni Adams, Akimichi Taketa, D. van Eijk, Daniel Bindig, G. H. Collin, T. C. Arlen, Robert Lahmann, J. J. Beatty, Tianlu Yuan, U. Nauman, Azadeh Keivani, Y. L. Li, Karl J. Clark, T. Kintscher, M. Song, T. L. Carver, Paras Koundal, Michael Kovacevich, Christian Glaser, Frederik Hermann Lauber, T. Huege, Erik Ganster, Benedikt Riedel, D. Seckel, Anna Nelles, R. G. Stokstad, F. McNally, R. Maunu, M. Prado Rodriguez, Kayla Leonard, N. Kurahashi, James E. Braun, Amy Connolly, Samvel Ter-Antonyan, A. Terliuk, Justin Lanfranchi, Pranav Dave, Jannis Necker, C. Wendt, S. Wren, A. Sharma, Sukeerthi Dharani, David Vannerom, M. H. Shaevitz, Alexander Trettin, Reina H. Maruyama, Francis Halzen, J. Merz, K. Krings, Rasha Abbasi, Ben Smithers, Qinrui Liu, M. J. Larson, T. Anderson, Summer Blot, G. de Wasseige, I. Ansseau, D. Hebecker, Jorge Torres, Killian Holzapfel, Martina Karl, C. J. Lozano Mariscal, John Hardin, Jean Pierre Twagirayezu, Daniel García-Fernández, T. Stezelberger, S. Mandalia, E. O'Sullivan, R. Hoffmann, M. Plum, Juliana Stachurska, H. Dembinski, C. Pérez de los Heros, S. Márka, G. WSullivan, A. Haungs, Paul Coppin, Z. Griffith, J. C. Gallagher, Saskia Philippen, Federica Bradascio, Jochen M. Schneider, Srubabati Goswami, Andrea Turcati, Wing Yan Ma, Nahee Park, Y. Makino, Sarah Mancina, C. Walck, M. Kauer, Suyong Choi, Anna Franckowiak, Tobias Hoinka, Chad Finley, David Kappesser, T. Gregoire, Ella Roberts, J. van Santen, S. De Ridder, Jan Weldert, Chunfai Tung, F. Jonske, Ken'ichi Kin, L. Halve, Philipp Eller, K. Hultqvist, N. L. Strotjohann, H. Dujmovic, Vedant Basu, M. A. Unland Elorrieta, Alex Pizzuto, K. D. de Vries, I. CMariş, Gerrit Wrede, R. Gernhaeuser, Thomas Huber, Matti Jansson, Thomas K. Gaisser, M. Richman, Christoph Tönnis, James DeLaunay, Gary Binder, K.-H. Becker, Ek Narayan Paudel, Allan Hallgren, U. Latif, Hiroyuki Tanaka, I. Safa, Steve Sclafani, J. Kiryluk, K. Andeen, P. B. Price, H. Schieler, Kirill Filimonov, Segev BenZvi, Alexander Fritz, D. Z. Besson, Darren Grant, Marjon Moulai, Yiqian Xu, Felix Henningsen, S. Robertson, Aswathi Balagopal, Francesco Lucarelli, Pisin Chen, Matt Dunkman, Merlin Schaufel, Patrick Allison, Spencer Klein, Cosmin Deaconu, Tim Ruhe, A. Ludwig, George Japaridze, Javier Gonzalez, C. B. Krauss, Roxanne Turcotte, T. O. B. Schmidt, Simona Toscano, Roger Moore, P. Heix, R. S. Busse, Chujie Chen, Pablo Correa, L. Gerhard, S. De Kockere, J. Felde, Surujhdeo Seunarine, R. Snihur, J. Buscher, D. Rysewyk Cantu, A. Weindl, R. Hellauer, Giorgio Maggi, H. Niederhausen, Mauricio Bustamante, D. Southall, Julia Böttcher, J. Bourbeau, Lenka Tomankova, Maryon Ahrens, A. Burgman, Christopher Wiebusch, Darko Veberič, Juanan Aguilar, T. R. Wood, Christian Spiering, Frederik Tenholt, R. Nagai, L. Schumacher, C. De Clercq, Benjamin Hokanson-Fasig, L. V. Nguyen, C. Lagunas Gualda, K. Hughes, Kara Hoffman, C. Alispach, J. M. LoSecco, Joshua Hignight, K. Helbing, Timo Sturwald, Xinyue Kang, Richard Naab, Kunal Deoskar, Janet Conrad, Zackary Meyers, K. Meagher, Mehmet Gunduz, Agnieszka Leszczyńska, R. C. Bay, David A. Williams, Kurt Woschnagg, M. Zöcklein, M. Silva, Claudio Kopper, Eric Oberla, Ramesh Koirala, E. Cheung, Thomas Stuttard, Martin Rongen, Najia Moureen Binte Amin, R. Cross, Paul Evenson, A. Karle, Sebastian Böser, Seongjin In, Johannes Werthebach, J. P. Lazar, Markus Ackermann, Austin Schneider, Yang Lyu, Justin Vandenbroucke, Juan Carlos Diaz-Velez, Beverley A. Clark, Timo Karg, Sarah Pieper, Hershal Pandya, Wolfgang Rhode, Zhedong Zhang, P. Schlunder, A. Ishihara, Elisa Resconi, Subir Sarkar, William Luszczak, Clara E. Hill, Ava Ghadimi, Alessio Porcelli, Alan Coleman, J. Auffenberg, Grant Parker, Robert Stein, Dirk Ryckbosch, Benjamin Bastian, Anastasia Maria Barbano, Abhishek Desai, T. Kittler, J. Nam, P. Mallik, E. Blaufuss, S. Zierke, T. Stanev, M. Bohmer, Stephan Meighen-Berger, Simone Garrappa, P. Muth, Dmitry Chirkin, M. E. Huber, Marcos Santander, Christoph Raab, Nadège Iovine, J. Becker Tjus, L. Classen, Colin Turley, S. C. Nowicki, K. Farrag, M. Kleifges, O. Kalekin, A. Olivas, Alexander Kappes, D. Berley, G. C. Hill, Abigail G. Vieregg, Frank G. Schröder, D. Heinen, Erin Carnie-Bronca, N. Kulacz, D. Tosi, J. C. Hanson, Bunheng Ty, Ralph Engel, Moritz Kellermann, Gisela Anton, Elisa Lohfink, Elisa Bernardini, Damian Pieloth, Ali Kheirandish, Jan Soedingrekso, Giovanni Renzi, Michael DuVernois, Jannes Brostean-Kaiser, K. Wiebe, S. Fahey, A. R. Fazely, Tyce DeYoung, J. Lünemann, Thomas Ehrhardt, Nathan Whitehorn, Immacolata Carmen Rea, M. U. Nisa, Aaron Fienberg, Gerald Przybylski, G. Krückl, L. Papp, Amirreza Raissi, L. Köpke, Chris Weaver, R. Halliday, Alejandro Diaz, Stephanie Bron, S. Söldner-Rembold, James Pinfold, Ryan Burley, M. Riegel, H. Bagherpour, Stephanie Wissel, Olga Botner, Y. Pan, A. Steuer, S. Tilav, D. Kang, M. deWith, V. Baum, J. P. Yanez, I. Taboada, Stephen L. Hauser, Raamis Hussain, Michael O. Wolf, M. Stamatikos, John Evans, Shefali Shefali, Christoph Welling, Abdul Rehman, Carsten Rott, K. Tollefson, A. Goldschmidt, Y. Popovych, Troels Petersen, S. E. Sanchez Herrera, Simeon Reusch, S. Hickford, Xianwu Xu, J. Sandroos, C. Bohm, R. Joppe, Spencer Axani, Sebastian Baur, Carlos Arguelles, Jessie Micallef, Teppei Katori, K. Rawlins, James Madsen, Lu Lu, M. G. Aartsen, T. Glüsenkamp, M. Meier, Michael Campana, P. Sandstrom, Kendall Mahn, B. J. P. Jones, K. Hoshina, Glenn Spiczak, Andres Medina, G. Momenté, D. Mockler, M. Rameez, D. F. Cowen, Daria Pankova, E. Friedman, R. Morse, T. Montaruli, E. Unger, Maximilian Karl Scharf, P. Peiffer, J. Stettner, Gerrit Roellinghoff, Mirco Hunnefeld, Marie Oehler, Max Renschler, D. J. Koskinen, E. Bourbeau, Spencer Griswold, Maria Tselengidou, D. Soldin, Z. Márka, Minjin Jeong, L. Rauch, S. Yoshida, N. van Eijndhoven, C. Haack, Emily Dvorak, D. R. Nygren, Marek Kowalski, Kael Hanson, Paolo Desiati, J. Haugen, Lars Steffen Weinstock, Johan Wulff, Won Nam Kang, Timothyblake Watson, X. Bai, G. Neer, Konstancja Satalecka, Theo Glauch, U. Katz, Alexander Sandrock, Ilse Plaisier, K. Mase, D. B. Fox, Hermann Kolanoski, M. J. Weiss, Stef Verpoest, Imre Bartos, David J. Smith, S. Kopper, René Reimann, Leander Fischer, F. Huang, Matthias Vraeghe, Physics, Faculty of Sciences and Bioengineering Sciences, Vriendenkring VUB, and Elementary Particle Physics

Subjects
Physics, High Energy Astrophysical Phenomena (astro-ph.HE), astro-ph.HE, Nuclear and High Energy Physics, Active galactic nucleus, 010308 nuclear & particles physics, High-energy astronomy, Gravitational wave, media_common.quotation_subject, Astrophysics::High Energy Astrophysical Phenomena, Astrophysics::Instrumentation and Methods for Astrophysics, Astronomy, FOS: Physical sciences, Cosmic ray, 01 natural sciences, Universe, Neutron star, 0103 physical sciences, Neutrino, Neutrino astronomy, Astrophysics - High Energy Astrophysical Phenomena, 010303 astronomy & astrophysics, media_common
Abstract

The observation of electromagnetic radiation from radio to $\gamma$-ray wavelengths has provided a wealth of information about the universe. However, at PeV (10$^{15}$ eV) energies and above, most of the universe is impenetrable to photons. New messengers, namely cosmic neutrinos, are needed to explore the most extreme environments of the universe where black holes, neutron stars, and stellar explosions transform gravitational energy into non-thermal cosmic rays. The discovery of cosmic neutrinos with IceCube has opened this new window on the universe. In this white paper, we present an overview of a next-generation instrument, IceCube-Gen2, which will sharpen our understanding of the processes and environments that govern the universe at the highest energies. IceCube-Gen2 is designed to: 1) Resolve the high-energy neutrino sky from TeV to EeV energies; 2) Investigate cosmic particle acceleration through multi-messenger observations; 3) Reveal the sources and propagation of the highest energy particles in the universe; 4) Probe fundamental physics with high-energy neutrinos. IceCube-Gen2 will increase the annual rate of observed cosmic neutrinos by a factor of ten compared to IceCube, and will be able to detect sources five times fainter than its predecessor. Furthermore, through the addition of a radio array, IceCube-Gen2 will extend the energy range by several orders of magnitude compared to IceCube. Construction will take 8 years and cost about \$350M. The goal is to have IceCube-Gen2 fully operational by 2033. IceCube-Gen2 will play an essential role in shaping the new era of multi-messenger astronomy, fundamentally advancing our knowledge of the high-energy universe. This challenging mission can be fully addressed only in concert with the new survey instruments across the electromagnetic spectrum and gravitational wave detectors which will be available in the coming years., Comment: 56 pages, 29 figures

Published
2020
Full Text
View/download PDF

5. IceCube Search for High-Energy Neutrino Emission from TeV Pulsar Wind Nebulae

Author

C. Haack, Immacolata Carmen Rea, Emily Dvorak, K.-H. Becker, K. Hoshina, Yiqian Xu, Matt Dunkman, K. Mase, Yuya Makino, Minjin Jeong, Timothyblake Watson, Thomas Meures, B. Relethford, E. Cheung, Saskia Philippen, M. J. Weiss, Konstancja Satalecka, Theo Glauch, L. Rauch, U. Katz, Thomas Stuttard, S. De Ridder, Jeffrey Lazar, P. B. Price, D. Heereman, S. Yoshida, D. B. Fox, S. Kopper, Sarah Pieper, K. Jero, N. L. Strotjohann, Hermann Kolanoski, Dirk Ryckbosch, Stef Verpoest, Colin Turley, Felix Henningsen, M. Zöcklein, René Reimann, C. Alispach, Lenka Tomankova, T. Grégoire, Timo Karg, A. Steuer, Stephan Meighen-Berger, Janet Conrad, Thomas Ehrhardt, Frank G. Schröder, A. R. Fazely, M. Silva, Francesco Lucarelli, Raamis Hussain, R. Cross, A. Obertacke Pollmann, E. Pinat, T. O. B. Schmidt, Johannes Werthebach, M. Usner, Kael Hanson, Karl J. Clark, Maximilian Meier, S. Hickford, R. Joppe, Delia Tosi, Sebastian Baur, Chujie Chen, A. Weindl, Maryon Ahrens, Frederik Tenholt, R. Nagai, K. Helbing, Won Nam Kang, X. Bai, G. Neer, Simona Toscano, P. Heix, R. Maunu, J. Lünemann, William Luszczak, S. Tilav, M. Medici, Christian Spiering, L. Wills, P. Muth, P. Schlunder, Daria Pankova, E. Friedman, R. S. Busse, M. Song, T. L. Carver, Mike Richman, Amirreza Raissi, Federica Bradascio, Alexander Burgman, T. R. Wood, Ramesh Koirala, J. P. Yanez, Karim Ghorbani, Spencer Axani, Christopher Wiebusch, Kunal Deoskar, Paolo Desiati, Chris Weaver, Stephanie Bron, Kurt Woschnagg, C. J. Lozano Mariscal, G. Merino, Tim Ruhe, Justin Vandenbroucke, H. Bagherpour, Alexander Sandrock, J. L. Kelley, Markus Ahlers, Martin Rongen, George Japaridze, Roger Moore, A. Ludwig, Olga Botner, Paul Evenson, M. G. Aartsen, N. Wandkowsky, H. Dujmovic, Merlin Schaufel, M. Stamatikos, E. Blaufuss, Ioana Codrina Maris, L. Wille, H. Niederhausen, Carlos Arguelles, Ibrahim Safa, V. Baum, Jessie Micallef, L. Classen, Damian Pieloth, Ali Kheirandish, N. Kurahashi, J. Bourbeau, D. Kang, Todor Stanev, K. Tollefson, Surujhdeo Seunarine, Albrecht Karle, D. van Eijk, Christoph Raab, Nadège Iovine, P. Mallik, Simone Garrappa, Dmitry Chirkin, S. C. Nowicki, W. Van Driessche, C. Wendt, Alexander Kappes, Erik Ganster, K. Mallot, R. Morse, James W. Wood, Z. Griffith, Jakob Bottcher, D. Berley, G. C. Hill, Bunheng Ty, R. Snihur, T. Montaruli, Jannes Brostean-Kaiser, Juanan Aguilar, G. de Wasseige, G. W. Sullivan, K. Rawlins, Donglian Xu, Seongjin In, B. J. P. Jones, Ralph Engel, Moritz Kellermann, Elisa Resconi, I. Taboada, Samvel Ter-Antonyan, Elisa Lohfink, James E. Braun, Gisela Anton, James Madsen, Lu Lu, Alessio Porcelli, T. Kintscher, Frederik Hermann Lauber, Giovanni Renzi, A. Goldschmidt, D. Hebecker, Qinrui Liu, R. Hoffmann, T. Glüsenkamp, Le Viet Nguyen, L. Köpke, D. Seckel, S. Fahey, Michael O. Wolf, Alexander Fritz, D. Z. Besson, Martina Karl, A. Wallace, A. Terliuk, Paul Coppin, Andrea Turcati, Justin Lanfranchi, J. van Santen, Mehr Nisa, Jochen M. Schneider, B. J. Whelan, Claudio Kopper, A. Ishihara, Tyce DeYoung, Andres Medina, Alexander Trettin, Nathan Whitehorn, Alex Pizzuto, D. R. Nygren, Gerald Przybylski, S. E. Sanchez Herrera, M. A. Unland Elorrieta, Gary Binder, R. Halliday, A. Haungs, C. Pérez de los Heros, K. Krings, D. Mockler, Nahee Park, K. Hultqvist, M. Wallraff, Darren Grant, Kendall Mahn, C. Walck, Alan Coleman, E. O’Sullivan, T. Anderson, Marek Kowalski, J. C. Gallagher, M. Plum, Subir Sarkar, Jan Weldert, Thomas K. Gaisser, G. B. Yodh, A. Kyriacou, Gerrit Wrede, K. Meagher, L. Halve, Philipp Eller, Thomas Huber, Allan Hallgren, Benjamin Hokanson-Fasig, Yang Lyu, Elisa Bernardini, J. Auffenberg, Chunfai Tung, J. Becker Tjus, J. Felde, J. Buscher, D. Rysewyk Cantu, Jenni Adams, P. Peiffer, Joshua Hignight, Timo Sturwald, H. Schieler, Kirill Filimonov, K. Wiebe, Steven Robertson, R. G. Stokstad, Segev BenZvi, Shefali Shefali, Spencer Klein, Abdul Rehman, Carsten Rott, Kara Hoffman, Javier Gonzalez, Roxanne Turcotte, Giorgio Maggi, Matthias Vraeghe, C. De Clercq, Hershal Pandya, Wolfgang Rhode, David A. Williams, Xianwu Xu, Robert Stein, J. Sandroos, Markus Ackermann, S. W. Barwick, C. Bohm, J. Kim, Daniel Bindig, K. D. de Vries, N. Kulacz, Brian Clark, Chad Finley, Christoph Tönnis, Pranav Dave, M. Günder, T. Stezelberger, G. H. Collin, Sarah Mancina, Anna Franckowiak, Tobias Hoinka, Kayla Leonard, Steve Sclafani, Jan Soedingrekso, Francis Halzen, J. Kiryluk, K. Andeen, I. Ansseau, G. Krückl, Juliana Stachurska, Alejandro Diaz, Pablo Correa, H. Dembinski, M. Kauer, Suyong Choi, David Kappesser, R. Hellauer, Matti Jansson, T. Palczewski, Sebastian Böser, Benjamin Bastian, Anastasia Maria Barbano, T. Kittler, B. Eberhardt, M. E. Huber, Marcos Santander, L. Gerhardt, A. Olivas, M. J. Larson, Wing Yan Ma, James DeLaunay, Marjon Moulai, J. J. Beatty, Tianlu Yuan, F. McNally, A. Stößl, Reina H. Maruyama, Summer Blot, F. Jonske, L. Schumacher, F. Huang, Mehmet Gunduz, Agnieszka Leszczyńska, R. C. Bay, Austin Schneider, Juan Carlos Diaz-Velez, Glenn Spiczak, G. Momenté, M. Rameez, D. F. Cowen, U. Naumann, E. Unger, A. O'Murchadha, Max Renschler, D. J. Koskinen, E. Bourbeau, Spencer Griswold, Maria Tselengidou, D. Soldin, J. Stettner, Mirco Hunnefeld, Marie Oehler, N. van Eijndhoven, Physics, Faculty of Sciences and Bioengineering Sciences, Vriendenkring VUB, and Elementary Particle Physics

Subjects
010504 meteorology & atmospheric sciences, High-energy astronomy, Astrophysics::High Energy Astrophysical Phenomena, Neutrino astronomy, High energy astrophysics, FOS: Physical sciences, Cosmic ray, Astrophysics, Astrophysics::Cosmology and Extragalactic Astrophysics, 01 natural sciences, 7. Clean energy, Pulsar, 0103 physical sciences, 010303 astronomy & astrophysics, Astrophysics::Galaxy Astrophysics, 0105 earth and related environmental sciences, Physics, High Energy Astrophysical Phenomena (astro-ph.HE), astro-ph.HE, Astronomy and Astrophysics, Galactic plane, COSMIC-RAYS, CRAB-NEBULA, Crab Nebula, Physics and Astronomy, 13. Climate action, Space and Planetary Science, GALACTIC SOURCES, DISCOVERY, Physique des particules élémentaires, High Energy Physics::Experiment, Neutrino, Astrophysics - High Energy Astrophysical Phenomena, GAMMA-RAY EMISSION, Lepton
Abstract

Pulsar wind nebulae (PWNe) are the main gamma-ray emitters in the Galactic plane. They are diffuse nebulae that emit nonthermal radiation. Pulsar winds, relativistic magnetized outflows from the central star, shocked in the ambient medium produce a multiwavelength emission from the radio through gamma-rays. Although the leptonic scenario is able to explain most PWNe emission, a hadronic contribution cannot be excluded. A possible hadronic contribution to the high-energy gamma-ray emission inevitably leads to the production of neutrinos. Using 9.5 yr of all-sky IceCube data, we report results from a stacking analysis to search for neutrino emission from 35 PWNe that are high-energy gamma-ray emitters. In the absence of any significant correlation, we set upper limits on the total neutrino emission from those PWNe and constraints on hadronic spectral components., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2020
Full Text
View/download PDF

6. In-situ calibration of the single-photoelectron charge response of the IceCube photomultiplier tubes

Author

M.G. Aartsen, M. Ackermann, J. Adams, J.A. Aguilar, M. Ahlers, M. Ahrens, C. Alispach, K. Andeen, T. Anderson, I. Ansseau, G. Anton, C. Argüelles, J. Auffenberg, S. Axani, P. Backes, H. Bagherpour, X. Bai, A. Balagopal V., A. Barbano, S.W. Barwick, B. Bastian, V. Baum, S. Baur, R. Bay, J.J. Beatty, K.-H. Becker, J. Becker Tjus, S. BenZvi, D. Berley, E. Bernardini, D.Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, C. Bohm, M. Börner, S. Böser, O. Botner, J. Böttcher, E. Bourbeau, J. Bourbeau, F. Bradascio, J. Braun, S. Bron, J. Brostean-Kaiser, A. Burgman, J. Buscher, R.S. Busse, T. Carver, C. Chen, E. Cheung, D. Chirkin, S. Choi, K. Clark, L. Classen, A. Coleman, G.H. Collin, J.M. Conrad, P. Coppin, P. Correa, D.F. Cowen, R. Cross, P. Dave, C. De Clercq, J.J. DeLaunay, H. Dembinski, K. Deoskar, S. De Ridder, P. Desiati, K.D. de Vries, G. de Wasseige, M. de With, T. DeYoung, A. Diaz, J.C. Díaz-Vélez, H. Dujmovic, M. Dunkman, E. Dvorak, B. Eberhardt, T. Ehrhardt, P. Eller, R. Engel, P.A. Evenson, S. Fahey, A.R. Fazely, J. Felde, K. Filimonov, C. Finley, D. Fox, A. Franckowiak, E. Friedman, A. Fritz, T.K. Gaisser, J. Gallagher, E. Ganster, S. Garrappa, L. Gerhardt, K. Ghorbani, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J.G. Gonzalez, D. Grant, Z. Griffith, S. Griswold, M. Günder, M. Gündüz, C. Haack, A. Hallgren, L. Halve, F. Halzen, K. Hanson, A. Haungs, D. Hebecker, D. Heereman, P. Heix, K. Helbing, R. Hellauer, F. Henningsen, S. Hickford, J. Hignight, G.C. Hill, K.D. Hoffman, R. Hoffmann, T. Hoinka, B. Hokanson-Fasig, K. Hoshina, F. Huang, M. Huber, T. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, S. In, N. Iovine, A. Ishihara, G.S. Japaridze, M. Jeong, K. Jero, B.J.P. Jones, F. Jonske, R. Joppe, D. Kang, W. Kang, A. Kappes, D. Kappesser, T. Karg, M. Karl, A. Karle, U. Katz, M. Kauer, J.L. Kelley, A. Kheirandish, J. Kim, T. Kintscher, J. Kiryluk, T. Kittler, S.R. Klein, R. Koirala, H. Kolanoski, L. Köpke, C. Kopper, S. Kopper, D.J. Koskinen, M. Kowalski, K. Krings, G. Krückl, N. Kulacz, N. Kurahashi, A. Kyriacou, M. Labare, J.L. Lanfranchi, M.J. Larson, F. Lauber, J.P. Lazar, K. Leonard, A. Leszczyńska, M. Leuermann, Q.R. Liu, E. Lohfink, C.J. Lozano Mariscal, L. Lu, F. Lucarelli, J. Lünemann, W. Luszczak, Y. Lyu, W.Y. Ma, J. Madsen, G. Maggi, K.B.M. Mahn, Y. Makino, P. Mallik, K. Mallot, S. Mancina, I.C. Mariş, R. Maruyama, K. Mase, R. Maunu, F. McNally, K. Meagher, M. Medici, A. Medina, M. Meier, S. Meighen-Berger, T. Menne, G. Merino, T. Meures, J. Micallef, D. Mockler, G. Momenté, T. Montaruli, R.W. Moore, R. Morse, M. Moulai, P. Muth, R. Nagai, U. Naumann, G. Neer, H. Niederhausen, M.U. Nisa, S.C. Nowicki, D.R. Nygren, A. Obertacke Pollmann, M. Oehler, A. Olivas, A. O'Murchadha, E. O'Sullivan, T. Palczewski, H. Pandya, D.V. Pankova, N. Park, P. Peiffer, C. Pérez de los Heros, S. Philippen, D. Pieloth, E. Pinat, A. Pizzuto, M. Plum, A. Porcelli, P.B. Price, G.T. Przybylski, C. Raab, A. Raissi, M. Rameez, L. Rauch, K. Rawlins, I.C. Rea, R. Reimann, B. Relethford, M. Renschler, G. Renzi, E. Resconi, W. Rhode, M. Richman, S. Robertson, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk, I. Safa, S.E. Sanchez Herrera, A. Sandrock, J. Sandroos, M. Santander, S. Sarkar, K. Satalecka, M. Schaufel, H. Schieler, P. Schlunder, T. Schmidt, A. Schneider, J. Schneider, F.G. Schröder, L. Schumacher, S. Sclafani, D. Seckel, S. Seunarine, S. Shefali, M. Silva, R. Snihur, J. Soedingrekso, D. Soldin, M. Song, G.M. Spiczak, C. Spiering, J. Stachurska, M. Stamatikos, T. Stanev, R. Stein, P. Steinmüller, J. Stettner, A. Steuer, T. Stezelberger, R.G. Stokstad, A. Stößl, N.L. Strotjohann, T. Stürwald, T. Stuttard, G.W. Sullivan, I. Taboada, F. Tenholt, S. Ter-Antonyan, A. Terliuk, S. Tilav, K. Tollefson, L. Tomankova, C. Tönnis, S. Toscano, D. Tosi, A. Trettin, M. Tselengidou, C.F. Tung, A. Turcati, R. Turcotte, C.F. Turley, B. Ty, E. Unger, M.A. Unland Elorrieta, M. Usner, J. Vandenbroucke, W. Van Driessche, D. van Eijk, N. van Eijndhoven, S. Vanheule, J. van Santen, M. Vraeghe, C. Walck, A. Wallace, M. Wallraff, N. Wandkowsky, T.B. Watson, C. Weaver, A. Weindl, M.J. Weiss, J. Weldert, C. Wendt, J. Werthebach, B.J. Whelan, N. Whitehorn, K. Wiebe, C.H. Wiebusch, L. Wille, D.R. Williams, L. Wills, M. Wolf, J. Wood, T.R. Wood, K. Woschnagg, G. Wrede, D.L. Xu, X.W. Xu, Y. Xu, J.P. Yanez, G. Yodh, S. Yoshida, T. Yuan, M. Zöcklein, Physics, Faculty of Sciences and Bioengineering Sciences, Vriendenkring VUB, and Elementary Particle Physics

Subjects
electron, Physics - Instrumentation and Detectors, Detector modelling and simulations II (electric fields, Physics::Instrumentation and Detectors, Monte Carlo method, 01 natural sciences, charge distribution, 030218 nuclear medicine & medical imaging, IceCube, 0302 clinical medicine, DESIGN, charge, emission, (photomultipliers, Instrumentation, Photon detectors for UV, physics.ins-det, Mathematical Physics, Physics, Detector, Astrophysics::Instrumentation and Methods for Astrophysics, Charge density, calibration [photomultiplier], Monte Carlo [numerical calculations], Instrumentation and Detectors (physics.ins-det), photomultiplier: calibration, Detector modelling and simulations II (electric fields, charge transport, multiplication and induction, pulse formation, electron emission, etc), Neutrino detector, HPDs, Physique des particules élémentaires, Neutrino, numerical calculations: Monte Carlo, others), photoelectron, Photomultiplier, data analysis method, pulse formation, Visible and IR photons (vacuum) (photomultipliers, HPDs, others), FOS: Physical sciences, Particle detector, IceCube Neutrino Observatory, 03 medical and health sciences, Optics, 0103 physical sciences, Physics::Atomic and Molecular Clusters, Visible and IR photons (vacuum) (photomultipliers, ddc:610, etc), multiplication and induction, 010308 nuclear & particles physics, business.industry, PERFORMANCE, visible and IR photons (vacuum), charge transport, Physics and Astronomy, electron emission, transport, business
Abstract

Journal of Instrumentation 15(06), P06032 (2020). doi:10.1088/1748-0221/15/06/P06032, We describe an improved in-situ calibration of the single-photoelectron charge distributions for each of the in-ice Hamamatsu Photonics R7081-02[MOD] photomultiplier tubes in the IceCube Neutrino Observatory. The characterization of the individual PMT charge distributions is important for PMT calibration, data and Monte Carlo simulation agreement, and understanding the effect of hardware differences within the detector. We discuss the single photoelectron identification procedure and how we extract the single-photoelectron charge distribution using a deconvolution of the multiple-photoelectron charge distribution., Published by Inst. of Physics, London

Published
2020
Full Text
View/download PDF

7. Publisher Correction: Detection of a particle shower at the Glashow resonance with IceCube

Author

Jeffrey Lazar, George Japaridze, Roger Moore, M. Zöcklein, D. B. Fox, Timo Karg, Federica Bradascio, Alexander Burgman, S. Sarkar, J. Bourbeau, J. S. Gallagher, Richard Naab, Jan Soedingrekso, Merlin Schaufel, Seongjin In, J. A. Aguilar, Hermann Kolanoski, Elisa Resconi, M. Kauer, M. E. Huber, Marcos Santander, Le Viet Nguyen, D. Kang, Sarah Mancina, Stef Verpoest, Anna Franckowiak, Tobias Hoinka, Alexander Trettin, Aswathi Balagopal, L. Gerhardt, A. Porcelli, K. Krings, Vedant Basu, A. Schneider, Suyong Choi, G. Krückl, David Kappesser, Steve Sclafani, Alan Coleman, Gerrit Wrede, I. Taboada, Dustin Hebecker, Thomas Huber, B. J. P. Jones, A. Olivas, Frank G. Schröder, Ek Narayan Paudel, Allan Hallgren, Sandro Kopper, R. Maunu, Tim Ruhe, Matti Jansson, Thomas Ehrhardt, S. H. Robertson, Christian Haack, A. Kyriacou, C. S. Hill, B. J. Whelan, David Vannerom, Joanna Kiryluk, J. Auffenberg, K. Hoshina, Glenn Spiczak, Pablo Correa, B. A. Clark, G. Momenté, Shefali Shefali, K. Filimonov, D. F. Cowen, Martin Unland Elorrieta, S. De Ridder, A. Wallace, U. Naumann, A. Goldschmidt, Christoph Tönnis, T. Anderson, John Hardin, Mohamed Rameez, Abdul Rehman, Jan Weldert, E. Unger, L. Halve, Thorsten Glusenkamp, Carsten Rott, R. Hellauer, Y. Popovych, Joonghan Kim, Elisa Bernardini, K. Woschnagg, Z. Griffith, M. Kowalski, Etienne Bourbeau, Maria Prado Rodriguez, K. Rawlins, I. C. Mariş, A. O. Pollmann, Chiara Bellenghi, Daria Pankova, E. Friedman, Timothy W. Schmidt, D. Tosi, Chujie Chen, K. Tollefson, Max Renschler, D. J. Koskinen, Elisa Lohfink, Jenni Adams, Xinyue Kang, H. Schieler, Surujhdeo Seunarine, A. Weindl, Johan Wulff, Timothyblake Watson, J. Felde, K. Helbing, David R. Williams, P. Schlunder, Claudio Kopper, Maryon Ahrens, J. Buscher, Spencer Griswold, James DeLaunay, C. Bohm, C. Alispach, James Madsen, Frederik Tenholt, Raffaela Busse, M. Richman, Roxanne Turcotte, Benjamin Bastian, Anastasia Maria Barbano, Maria Tselengidou, Marjon Moulai, M. Medici, Xu X. W., Anatoli Fedynitch, C. H. Wiebusch, Simeon Reusch, Markus Ahlers, S. Hickford, Lu Lu, Cristina Lagunas Gualda, P. B. Price, Michael DuVernois, K. Meagher, T. Kittler, Paul Coppin, Andrea Turcati, C. Pérez de los Heros, Konstancja Satalecka, Theo Glauch, Francesco Lucarelli, S. Böser, Ramesh Koirala, R. G. Stokstad, Jannis Necker, Robert A. Cross, J. van Santen, K. D. de Vries, J. Stettner, Johannes Werthebach, L. Schumacher, A. Ishihara, C. De Clercq, N. L. Strotjohann, Karen Andeen, N. Kulacz, Gerald Przybylski, Michael J Larson, Teresa Montaruli, Felix Henningsen, T. R. Wood, E. Blaufuss, Alex Pizzuto, Michael Campana, Cristian Jesus Lozano Mariscal, Kendall Mahn, A. Steuer, Erik Ganster, T. Kintscher, Markus Ackermann, S. W. Barwick, Gerrit Roellinghoff, William Luszczak, Hershal Pandya, Alexander Fritz, Pranav Dave, A. R. Fazely, J. L. Kelley, Sebastian Sanchez Herrera, Benjamin Hokanson-Fasig, T. Stanev, Paul Evenson, L. Classen, N. Wandkowsky, Wolfgang Rhode, R. Morse, Jakob Bottcher, Mirco Hunnefeld, Marie Oehler, Julia Becker Tjus, Samvel Ter-Antonyan, Robert Stein, Hrvoje Dujmovic, Frederik Hermann Lauber, Yang Lyu, Stephen L. Hauser, S. Tilav, Grant Parker, G. H. Collin, Saskia Philippen, C. Wendt, Gary Binder, Simona Toscano, P. Heix, S. Y. BenZvi, Raamis Hussain, P. Muth, C. B. Finley, T. Stezelberger, A. Desai, Simone Garrappa, Feifei Huang, Dmitry Chirkin, Gisela Anton, Spencer Axani, Andrew Ludwig, A. Terliuk, G. de Wasseige, K. Wiebe, R. Hoffmann, Kayla Leonard, Alexander Kappes, G. Maggi, C. Walck, J. Lünemann, D. Z. Besson, Carlos Arguelles, Sukeerthi Dharani, Justin Lanfranchi, Francis Halzen, J. Merz, J. G. Gonzalez, Jessie Micallef, Ibrahim Safa, Damian Pieloth, M. U. Nisa, Thomas K. Gaisser, R. Engel, K.-H. Becker, Yiqian Xu, Matt Dunkman, R. Joppe, I. Ansseau, Christian Spiering, Aaron Fienberg, M. Silva, Najia Moureen Binte Amin, Juliana Stachurska, Lenka Tomankova, Amirreza Raissi, Mehmet Gunduz, Chris Weaver, Stephanie Bron, Justin Vandenbroucke, Frank McNally, Chunfai Tung, Colin Turley, Jannes Brostean-Kaiser, E. Cheung, Thomas Stuttard, M. Plum, Sarah Pieper, Maximilian Karl Scharf, A. Kheirandish, Dirk Ryckbosch, M. Stamatikos, Stephan Meighen-Berger, Joakim Sandroos, Y. L. Li, Devyn Rysewyk Cantu, Daniela Mockler, Agnieszka Leszczyńska, Martin Wolf, P. Peiffer, R. C. Bay, Joshua Hignight, Timo Sturwald, R. Halliday, Ben Smithers, Jean Pierre Twagirayezu, L. Köpke, A. Haungs, Nahee Park, K. Hultqvist, Darren Grant, Sarah Nowicki, Ryo Nagai, J. P. Yanez, H. Bagherpour, M. G. Aartsen, K. D. Hoffman, S. Baur, Olga Botner, V. Baum, G. W. Sullivan, James E. Braun, Juan Carlos Diaz-Velez, Erin O'Sullivan, Sreetama Goswami, F. Jonske, Ken'ichi Kin, J. J. Beatty, Tianlu Yuan, H. Dembinski, Reina H. Maruyama, Summer Blot, Naoko Kurahashi, Qinrui Liu, S. R. Klein, Martina Karl, Jochen M. Schneider, Martin Rongen, Zhedong Zhang, Ava Ghadimi, P. Mallik, Hans Niederhausen, K. Mase, Yuya Makino, Karl J. Clark, Alberto Martin Gago Medina, M. J. Weiss, René Reimann, Leander Fischer, D. van Eijk, Christoph Raab, Nadège Iovine, M. Song, D. Berley, G. C. Hill, T. L. Carver, Paras Koundal, Bunheng Ty, Woosik Kang, Kael Hanson, Moritz Kellermann, Giovanni Renzi, D. Seckel, S. Fahey, D. R. Nygren, Tyce DeYoung, Nathan Whitehorn, Immacolata Carmen Rea, Jan Conrad, Ma W. Y., Michael Kovacevich, X. Bai, G. Neer, A. Diaz, Robert Snihur, Philipp Eller, Alexander Sandrock, Kunal Deoskar, A. Karle, Rasha Abbasi, Maximilian Meier, Paolo Desiati, Matthias Vraeghe, Minjin Jeong, L. Rauch, D. Soldin, S. Yoshida, Daniel Bindig, N. van Eijndhoven, Timothée Grégoire, Emily Dvorak, M. Relich, Benedikt Riedel, and U. Katz

Subjects
Physics, Particle physics, Multidisciplinary, Particle shower, Glashow resonance
Published
2021
Full Text
View/download PDF

8. Time-integrated Neutrino Source Searches with 10 years of IceCube Data

Author

Federica Bradascio, Alexander Burgman, Merlin Schaufel, Daria Pankova, E. Friedman, Claudio Kopper, Subir Sarkar, Chad Finley, J. J. Beatty, Tianlu Yuan, M. Kauer, D. Kang, Christoph Tönnis, Frank G. Schröder, Alexander Fritz, D. Z. Besson, K. Mase, Yuya Makino, R. Morse, Suyong Choi, I. Taboada, R. Maunu, David Kappesser, Michael O. Wolf, Minjin Jeong, Thomas Meures, N. L. Strotjohann, Felix Henningsen, A. R. Fazely, E. Pinat, Simona Toscano, P. Heix, K. Jero, Sander Vanheule, N. Kurahashi, Karl J. Clark, S. De Ridder, Z. Griffith, Jenni Adams, J. Lünemann, C. Pérez de los Heros, A. Obertacke Pollmann, Aswathi Balagopal, Saskia Philippen, D. Rysewyk, M. Song, T. L. Carver, Mike Richman, J. L. Kelley, Markus Ahlers, K. Meagher, F. McNally, M. J. Weiss, M. Labare, T. Palczewski, C. Wendt, E. O’Sullivan, S. Hickford, Jan Soedingrekso, M. Stamatikos, S. Kopper, René Reimann, A. O'Murchadha, Lenka Tomankova, Chunfai Tung, P. Peiffer, M. J. Larson, Pranav Dave, Timothyblake Watson, Erik Ganster, T. Menne, G. de Wasseige, B. Eberhardt, A. Stößl, L. Rauch, Benjamin Hokanson-Fasig, Yang Lyu, Samvel Ter-Antonyan, M. Silva, R. G. Stokstad, B. Relethford, S. Yoshida, Won Nam Kang, Amirreza Raissi, Chris Weaver, Stephanie Bron, Max Renschler, D. J. Koskinen, Wing Yan Ma, Tim Ruhe, B. J. P. Jones, R. Hoffmann, B. J. Whelan, X. Bai, G. Neer, E. Bourbeau, C. J. Lozano Mariscal, G. Merino, Reina H. Maruyama, James DeLaunay, C. Alispach, G. Krückl, Konstancja Satalecka, N. Wandkowsky, H. Dujmovic, Janet Conrad, K. Wiebe, Marjon Moulai, Summer Blot, Andres Medina, Theo Glauch, Jan Weldert, Thomas Ehrhardt, Spencer Griswold, Steven Robertson, Joshua Hignight, L. Halve, Philipp Eller, Shefali Shefali, D. Mockler, M. Günder, Alejandro Diaz, R. Cross, Timo Sturwald, H. Niederhausen, Kael Hanson, Surujhdeo Seunarine, R. Snihur, A. Weindl, Maria Tselengidou, D. Soldin, Johannes Werthebach, Carsten Rott, Juanan Aguilar, T. Stezelberger, R. Joppe, D. van Eijk, Joshua A. Wood, J. Felde, C. Walck, Jeffrey Lazar, R. Hellauer, J. Buscher, P. Schlunder, Maryon Ahrens, Alan Coleman, William Luszczak, Alexander Sandrock, Frederik Tenholt, R. Nagai, A. Goldschmidt, L. Schumacher, M. Zöcklein, Xianwu Xu, M. Medici, J. Sandroos, Timo Karg, T. Stanev, Maximilian Meier, Thomas K. Gaisser, G. B. Yodh, P. Steinmüller, F. Huang, G. H. Collin, Matthias Vraeghe, J. Stettner, J. Kim, Delia Tosi, U. Katz, Mehmet Gunduz, Agnieszka Leszczyńska, M. E. Huber, Marcos Santander, Paolo Desiati, S. E. Sanchez Herrera, R. C. Bay, K. D. de Vries, Sebastian Baur, Sebastian Böser, P. Backes, Gisela Anton, Elisa Bernardini, G. W. Sullivan, H. S. Matis, D. B. Fox, L. Gerhardt, A. Olivas, Austin Schneider, James E. Braun, N. van Eijndhoven, K. Helbing, C. Haack, Juan Carlos Diaz-Velez, H. Bagherpour, Benjamin Bastian, Anastasia Maria Barbano, T. Kittler, Daniel Bindig, Hermann Kolanoski, K. Becker, Emily Dvorak, N. Kulacz, Olga Botner, Kayla Leonard, D. R. Nygren, Javier Gonzalez, Roxanne Turcotte, Marek Kowalski, D. Hebecker, F. Jonske, Alexander Trettin, Giorgio Maggi, Mirco Hunnefeld, Marie Oehler, V. Baum, Sarah Mancina, Anna Franckowiak, Tobias Hoinka, Francis Halzen, J. Auffenberg, M. Börner, Steve Sclafani, J. Kiryluk, C. De Clercq, S. Tilav, I. Ansseau, Paul Coppin, Andrea Turcati, J. C. Gallagher, M. Leuermann, K. Andeen, Elisa Lohfink, J. P. Yanez, Gerrit Wrede, K. Hoshina, Thomas Huber, David A. Williams, Allan Hallgren, Juliana Stachurska, J. van Santen, H. Dembinski, Alex Pizzuto, Markus Ackermann, Glenn Spiczak, G. Momenté, M. G. Aartsen, Pablo Correa, S. W. Barwick, M. Rameez, D. F. Cowen, Gary Binder, Gerald Przybylski, U. Naumann, R. Halliday, George Japaridze, Roger Moore, E. Unger, A. Kyriacou, J. Bourbeau, K. Krings, Seongjin In, Elisa Resconi, Yiqian Xu, Matt Dunkman, Alessio Porcelli, M. Plum, J. Becker Tjus, E. Cheung, Ramesh Koirala, Thomas Stuttard, Dirk Ryckbosch, Stephan Meighen-Berger, K. Tollefson, E. Blaufuss, Albrecht Karle, Qinrui Liu, T. Glüsenkamp, L. Classen, Martina Karl, Jochen M. Schneider, M. A. Unland Elorrieta, D. Heereman, M. Wallraff, A. Steuer, Raamis Hussain, Colin Turley, T. Anderson, Immacolata Carmen Rea, Andreas Haungs, A. Ishihara, K. Mallot, H. Schieler, Kirill Filimonov, Segev BenZvi, T. Kintscher, M. Usner, Frederik Hermann Lauber, Spencer Klein, A. Terliuk, Justin Lanfranchi, Kara Hoffman, Julia Böttcher, Christian Spiering, Hershal Pandya, Wolfgang Rhode, Robert Stein, Justin Vandenbroucke, L. Wills, P. Muth, Ioana Codrina Maris, S. C. Nowicki, Christian Bohm, Ibrahim Safa, Damian Pieloth, Ali Kheirandish, W. Van Driessche, Nahee Park, K. Hultqvist, Darren Grant, Jannes Brostean-Kaiser, Christoph Raab, Nadège Iovine, M. U. Nisa, L. Köpke, D. Berley, G. C. Hill, Bunheng Ty, Ralph Engel, Giovanni Renzi, K. Rawlins, D. Seckel, S. Fahey, Tyce DeYoung, Nathan Whitehorn, Martin Rongen, R. S. Busse, Christopher Wiebusch, Kunal Deoskar, James Madsen, Lu Lu, L. Wille, Teresa Montaruli, Kendall Mahn, P. B. Price, Francesco Lucarelli, T. O. B. Schmidt, C. Chen, Karim Ghorbani, Spencer Axani, T. R. Wood, Carlos Arguelles, Jessie Micallef, P. Mallik, Kurt Woschnagg, Paul Evenson, Simone Garrappa, Dmitry Chirkin, Alexander Kappes, A. Wallace, Da Xu, Physics, Faculty of Sciences and Bioengineering Sciences, Elementary Particle Physics, and Vriendenkring VUB

Subjects
background [atmosphere], Astrophysics::High Energy Astrophysical Phenomena, media_common.quotation_subject, General Physics and Astronomy, FOS: Physical sciences, Astrophysics::Cosmology and Extragalactic Astrophysics, 01 natural sciences, IceCube, particle source [neutrino], TRACK RECONSTRUCTION, 0103 physical sciences, ddc:530, atmosphere [muon], 010306 general physics, Astrophysics::Galaxy Astrophysics, media_common, astro-ph.HE, Physics, High Energy Astrophysical Phenomena (astro-ph.HE), Muon, Astrophysics::Instrumentation and Methods for Astrophysics, Northern Hemisphere, Astronomy, Galaxy, messenger, Physics and Astronomy, Sky, correlation, time dependence, upgrade, galaxy, Neutrino, Astrophysics - High Energy Astrophysical Phenomena, statistical
Abstract

Physical review letters 124(5), 051103 (1-9) (2020). doi:10.1103/PhysRevLett.124.051103, This paper presents the results from point-like neutrino source searches using ten years of IceCube data collected between April 6, 2008 and July 10, 2018. We evaluate the significance of an astrophysical signal from a point-like source looking for an excess of clustered neutrino events with energies typically above $\sim1\,$TeV among the background of atmospheric muons and neutrinos. We perform a full-sky scan, a search within a selected source catalog, a catalog population study, and three stacked Galactic catalog searches. The most significant point in the Northern hemisphere from scanning the sky is coincident with the Seyfert II galaxy NGC 1068, which was included in the source catalog search. The excess at the coordinates of NGC 1068 is inconsistent with background expectations at the level of $2.9\,\sigma$ after accounting for statistical trials. The combination of this result along with excesses observed at the coordinates of three other sources, including TXS 0506+056, suggests that, collectively, correlations with sources in the Northern catalog are inconsistent with background at 3.3$\,\sigma$ significance. These results, all based on searches for a cumulative neutrino signal integrated over the ten years of available data, motivate further study of these and similar sources, including time-dependent analyses, multimessenger correlations, and the possibility of stronger evidence with coming upgrades to the detector., Published by APS, College Park, Md.

Published
2019
Full Text
View/download PDF

11. The Command Support At-Sea Experiment

Author

Daniel M. Sunday and David J. Buscher

Subjects
Rapid prototyping, Engineering drawing, Engineering, Tactical communications system, business.industry, Tomahawk, Ocean Engineering, Overlay, Weapon system, Missile, Graphics, business, Simulation, Coding (social sciences)
Abstract

The Command Support At-Sea Experiment (CS@SE) provides experimental advanced graphics display systems consisting of large screen color displays and operator console color displays in the combat information center (CIC) of an Aegis cruiser and in the tactical flag command center (TFCC) of an aircraft carrier. CS@SE systems are designed to prototype potential command support capabilities in an at-sea environment to validate and refine requirements for planned production system upgrades. These systems use sophisticated color graphics techniques to provide real-time tactical displays that improve the availability of information to an operator by reducing clutter through the use of color, area fill, transparen overlays and intensity coding of track symbols. Interfaces wen developed with the Aegis Display System (ADS), Shipboarc Gridlock System with Auto-correlation (SGS/AC), Flag Dats Display System (FDDS) and Tomahawk Engagement Planning and Exercise Evaluation System (TEPEE) that provided the data for the presentation of a tactical display. Display elements included both real-time and over-the-horizon (OTH) surface track data, velocity leaders, tags, uncertainty ellipses, and history trails. The display also included filled land masses, country boundaries, commercial airways, cities, graphics overlays (i.e., operational areas), weapon system missile performance contours, and engagement plans. This paper describes the experiment, its installation and integration into the shipboard environments of an Aegis cruiser (USS Leyte Gulf) and an aircraft carrier (USS America, its usage by the ships companies and embarked staffs, and the experiment result! and findings. Key conclusions of the experiment are: 1 Advanced graphics color displays can significantly enhance the ability of the warfighter to assimilate a complex tactical display. 2 Both ships reported a requirement for a correlated OTH and real-time track display with the ability to clearly differentiate the two types of tracks on the display. 3 On-line data bases such as detailed maps, airways, political boundaries, and cities provide important information that enhances the tactical track picture and the decision making process. 4 Classical rapid prototyping permits the validation of proposed command support concepts in an operational environment and permits some engineering evaluation of possible future capabilities.

Published
1990
Full Text
View/download PDF

12. Study of exciton dynamics in garnets by low temperature thermo-luminescence

Author

C. R. Varney, David T. Mackay, J. Buscher, and Farida Selim

Subjects
Condensed Matter::Quantum Gases, Materials science, Band gap, Exciton, Doping, General Physics and Astronomy, chemistry.chemical_element, Activation energy, Yttrium, Molecular physics, Thermoluminescence, Condensed Matter::Materials Science, chemistry, Physics::Atomic Physics, Atomic physics, Luminescence, Spectroscopy
Abstract

Shallow traps that affect exciton dynamics in undoped and Ce doped yttrium aluminum garnet (CeYAG) single crystals were studied by low temperature thermo-luminescence spectroscopy. The nature of traps was identified and their energy levels in the band gap were measured. Three types of traps were found: two very shallow traps with activation energy of less than 0.2 eV associated with electronic defects, one trap with activation energy of 0.5 eV associated with oxygen vacancies, and one relatively deeper trap with activation energy of 0.7 eV associated with hydrogen impurities. The association of oxygen vacancies with shallow traps as evident from this work and with deep traps as reported by Varney et al. [J. Appl. Phys. 111, 063505 (2012)] suggest their presence in the lattice in more than one charge state.

Published
2012
Full Text
View/download PDF

13. Die Papier‐Chromatographie auf dem Fettgebiet XLIII. Mitteilung: Beitrag zur Analyse der Alkydharze

Author

F. J Buscher and H. P. h. c. Kaufmann

Subjects
chemistry.chemical_classification, Chromatography, Chemistry, Fatty acid, Saponification
Abstract

Es werden die ersten Ergebnisse der Anwendung der qualitativen und quantitativen pc-Analyse auf die Untersuchung von Alkydharzen beschrieben. Verschiedene Alkydharze industrieller Herkunft werden auf dem Papier verseift und die Fettsauren papierchromatographisch getrennt. Die quantitative Auswertung erfolgte photometrisch nach Anfarbung mit Kupferacetat und alkoholischer Rubeanwasserstoff-Losung. Die Hydrierdifferenz-Methode zur Erkennung kritischer Fettsaurepartner hatte bei Anwendung von kolloidalem Palladium keinen Erfolg. Zum Vergleich wurden die zur Herstellung der Alkydharze verwendeten Ole und die aus den Harzen praparativ isolierten Fettsauren ebenfalls chromatographisch analysiert. A Contribution to the Analysis of Alkyd-Resins The authors describe the first results of the applications of qualitative and quantitative pc-analysis for the investigation of alkyd-resins. Different alkyd-resins from the industry are saponified on the paper and the fatty acids are separated by paperchromatography. The quantitative estimations were done photometrically after coloring with copper acetat and alcoholic solution of rubeanic acid. The hydrogenation-difference-method for the identification of critical fatty acid partners using colloidal palladium is not successful. For comparison the oils used for the preparation of alkyd-resins and the isolated fatty acids prepared from the resins are likewise analysed by paperchromatography.

Published
1960
Full Text
View/download PDF

14. A SOFTWARE SYSTEM ORIENTED TO FUZE TESTING (SOSOFT)

Author

Donald A Link and David J Buscher

Subjects
Engineering, Software, Proximity fuze, business.industry, Integration testing, Embedded system, White-box testing, System testing, Fuze, Software system, business, System integration testing, Reliability engineering
Abstract

Software techniques used in an automated real-time fuze testing system are discussed. Most of the techniques are independent of the electrical circuit being tested and the computer controlling the system. Although the software described was initially designed for testing the XM596 proximity fuze, only the actual fuze testing programs need be specifically designed for a given testing system. The programs comprising SOSOFT are functionally organized into eight major subsystems--real-time priority scheduling system, interrupt servicing system, input/output control system, executive utility system, basic testing system, data-display system, conversational control system, and reliability monitoring system.

Published
1970
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results