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In the several areas of Analytical chemistry such as biochemistry, pharmaceutical and food applications, the quantitative analysis of vitamin C has become an important subject. Vitamin C plays an important role in maintaining human health. During COVID -19 pandemic and current situation of various influenza viral infections Vitamin C possesses positive impacts on curing infection and it may play a protective role through improving the immune system. There are numerous methods for the determination of vitamin C in a variety of natural samples, biological fluids and pharmaceutical formulations. In the present work, it was aimed to determine and compare the Vitamin C concentration in some fresh fruits available in the middle region of Gujarat by using Titrimetric and UV spectrophotometric methods. It was found that vitamin C content of fruits commonly consumed at middle region of Gujarat; highest in Guava (108.50 mg/100gm by UV Spectrophotometric method and 157.38 mg/100gm by Redox titration method) and lowest in pineapple (16.24 mg/100gm by UV Spectrophotometric method and 20.53 mg/100gm by Redox titration method). These observations may serve as pointers on selection of fruits that can be consumed to match the requirement of vitamin C.

Hal yang melatarbelakangi kegiatan pengabdian ini adalah motivasi yang belum maksimal dari siswa - siswi, baik dari dalam diri sendiri maupun dari luar diri untuk menjadi seorang wirausaha diusia belia. Tujuan dari kegiatan ini adalah Mengimplementasikan Tridharma Perguruan Tinggi, Khususnya Pengabdian Kepada Masyarakat, Membekali wawasan berwirausaha bagi siswa SMA Katolik Cinta Kasih Tebing Tinggi dan Memotivasi dalam pengembangan wirausaha yang ada di SMA Katolik baik dari segi manajemen dan pemasarannya.Adapun Metode dalam kegiatan pengabdian ini adalah ceramah yaitu dengan memberian materi dan diskusi tanya jawab secara langsung serta menjawab post test tentang minat berwirausaha. Dan simpulan dari kegiatan pengabdian ini adalah Dosen – dosen Sekolah Tinggi Ilmu Ekonomi Bina Karya Tebing Tinggi mampu menjalankan Tridharma Perguruan Tinggi di bidang Pengabdian Kepada Masyarakat dengan pengaplikasian ilmu yang dimiliki di bidang Manajemen dan Kewirausahaan. Bagi siswa – siswi SMA Katolik Cipta Kasih Tebing Tinggi memperoleh ilmu yang bermanfaat dan dapat diterapkan di masyarakat dalam kehidupan kedepannya serta dapat menimbulkan jiwa kewirausahaan serta mengembangkan bakat siswa dalam berwirausaha dan Pengabdian ini juga akan dilakukan bertahap dan berkesinambungan untuk mengantarkan siswa – siswi SMA Katolik Cinta Kasih Tebing Tinggi tetap berkarya dan mau menjadi sukses diusia belia.

Pelaksanaan pembelajaran tatap muka terbatas dimasa pandemi Covid-19 mewajibkan seluruh akademisi pendidikan diwajibkan untuk mendapatkan vaksinasi, termasuk di STIE Bina Karya Tebing Tinggi. Hal ini sesuai dengan surat keputusan bersama 4 (empat) menteri No. 23425/A5/ HK.01.04/2021 tanggal 8 Agustus 2021 perihal panduan penyelengaraan pembelajaran di masa pandemi Covid-19 dan instruksi Gubernur Sumatera Utara No. 188.54/39/INST/2021 tanggal 30 Agustus 2021. Uraian permasalahan inti dari kegiatan pengabdian masyarakat ini adalah membantu program pemerintah dalam percepatan tingkat pencapaian vaksinasi di lingkungan pendidikan dan memenuhi kewajiban dalam melakukan kegiatan pembelajaran tatap muka di lingkungan akademik. Metode yang dilakukan dalam pengabdian ini adalah melalui perencanaan, pelaksanaan dan evaluasi. Metode evaluasi yang digunakan dalam kegiatan ini adalah reduksi data. Hasil dalam pengabdian ini adalah kegiatan berjalan maksimal dalam rangka memutus mata rantai penyebaran Covid-19 di kota Tebing Tinggi. Pencapaian target dalam kegiatan ini sudah mencapai 100 persen. Implementasi dari kegiatan pengabdian ini masih terjadi adanya kekurangan dalam pelaksanaan aksi vaksinasi peduli covid-19 dan gerakan kembali ke kampus terletak pada kuota vaksin yang terbatas untuk masyarakat dan terpenuhi untu sivitas akademik STIE Bina Karya Tebing Tinggi.

The purpose of this study was to determine the impact of the Corporate Social Responsibility Program of PT. Indonesia Asahan Aluminum towards the welfare of the people of Batu Bara Regency. The variables in this research consist of Corporate Social Responsibility and Community Welfare. This research was conducted on the people of Sei Suka Subdistrict, Batu Bara Regency as many as 56,078 people, based on the slovin formula, 100 respondents were obtained as samples. The method in this research is descriptive quantitative using instruments in the form of a questionnaire / questionnaire, observation and interviews with Likert scale measurements. From the results of Simple Linear Regression Analysis, it shows that Corporate Social Responsibility (CSR) has a positive effect on Community Welfare. Based on the Coefficient of Determination Test, the R value states that the adjusted R value is 35.9%, which means that the welfare of the community is influenced by Corporate Social Responsibility (CSR), while the remaining 63.1% is influenced by other variables not examined in this study. From the results of the partial analysis (t test), the independent variable Corporate Social Responsibility (CSR) has a significant effect on the dependent variable, namely Community Welfare. This can be seen in the Coefficient table through hypothesis testing, it can be seen that the calculation results partially have a significant and significant effect on the Community Welfare variable.

7 Higher education creates professionals, thinkers, future teachers, researchers, economists and knowledge workers, who, besides inhabiting knowledge societies, can be instrumental in creating them. Higher education also has a direct correlation with GDP, health indicators, and development (World Bank, 2002). The current scenario of higher education is marked by various problems of access, equity, and quality. The ills that afflict higher education in the country relate to outdated and rigid curricula, large number of vacant faculty positions, poor faculty quality in terms of both commitment and competence, poor systemic enablers for student mobility, absence of research, minimal and poor extension work, low levels of skill development, low employability, flawed and rigid system of examination, poor methods of teaching and learning, presence of strong vested interests, poor management and educational services, and problems of governance in the ecosystem of higher education. As we grapple with all these problems, Information and Communications Technology (ICT) comes through as a possible silver bullet offering a lot of promise and prospects. With the possibilities of ICT-driven access to quality education, 24X7 availability of educational resources, penetration of Internet, and the now available mobile access to these resources, a fresh perspective on the approach to solving the problems afflicting higher education becomes possible.

The Chief Executive Officer of SCOPE (Society for Creation of Opportunity through Proficiency in English) has to decide which of two models, a public-private partnership model which trained interested youth in the language and certified them, or an Only Assessment Scheme, which only tested and certified candidates, needed to receive greater emphasis. SCOPE, a government programme to develop English competence among youth, was in its fifth year, but the initial targets set for it were yet to be achieved.

This paper presents the results of a study on the perceived challenge of e-learning with special reference to the National Program for Technology Enhanced Learning (NPTEL) offered by the Indian Institutes of Technology (IITs) and Indian Institute of Science (IISc)jointly. The programme has been used to model learner requirement and expectations through technology enhanced and online learning worldwide. Survey data collected from across India is used to identify the predominant sections of users that feel "e-learning is challenging" and hence aren't able to engage fully in the e-learning process. Such findings will also have direct bearing on future design of all online learning processes worldwide through Massive Open Online Courses (MOOCs). An attempt is also made to identify the causes of this perception and corroborate the same with an analysis of the survey data. Finally, along with the results of the analysis, some suggestions for NPTEL and other online content providers worldwide, following the movement by UNESCO to create Open Educational Resources (OERs), are also given to help them chart their future courses of action. On the user side, some of these suggestions may also be helpful for overcoming this perception by addressing the roots of similar problems.

This paper studies and evaluates Technology Enhanced learning, with particular reference to the National Program for Technology Enhanced Learning (NPTEL) a portal dedicated to technical e-content across different Engineering Colleges of India. Based on a comprehensive survey conducted across the Engineering Colleges with over 5161 respondents, predominantly from western India, this study is a quantitative analysis of the findings and preferences articulated by students and faculty members. The questions pertain to the use, quality and relevance of e-content, such as NPTEL, used by students. Questions related to faculty quality, need for online educational services, content, technologies, pedagogies, research and extension are also posed to the sample. The responses of 5161 respondents are compared and analyzed across their current profile and opinion statements on NPTEL regarding whether NPTEL leads to enrichment, whether NPTEL can supplement classroom teaching and their preferred language for lecture content. The results and findings of the paper can be of use for further modifications of NPTEL for phase II.

Electrolyte flow distribution is an important factor that contributes to the performance of the overall efficiency of a redox flow battery system. In the present paper, a comparative study of the hydrodynamics of the serpentine and interdigitated flow fields has been performed. Ex situ experiments were conducted using the two flow fields in conditions typical of flow battery applications. Limited in situ testing has also been conducted. These bring out the surprising result that the pressure drop in the interdigitated flow field is less than that in the serpentine for the same flow rate. Computational fluid dynamics studies show strong under-the-rib convection in the reaction zone exists in both flow fields but with a shorter residence time in case of the interdigitated. It is posited that this may explain the superior electrochemical performance of cells with interdigitated flow fields. � 2014 Springer Science+Business Media Dordrecht.

In recent decades, there has been a manifold increase in the scope of technical knowledge, leading to a heavy demand for technical education. NPTEL is an Indian portal dedicated to technical e-content. This paper studies the effect of NPTEL on students of eight engineering colleges of Gujarat using the cluster analysis method. It brings out the variations in perceptions and preferences of students using NPTEL. These preferences, inter-alia, relate to use of local language, enrichment of knowledge, passing of examination, employability, educational services, community based extension work and research options among others. Interestingly, a near clear agreement emerges in need for a comprehensive online study program with examination and certification. The need to incorporate features of experiential learning in terms of carrying out actual live research, extension, teaching and working with the local community and industry are also clearly emerging.

Indian economy is growing at a fast pace presently. Sustaining this growth requires technically trained professionals in large number. It requires providing education and training to population in increasing number. The technological advancement can be of great help in this regard. This paper studies and evaluates Technology Enhanced learning, with particular reference to NPTEL -- a portal dedicated to technical e-content -- across eight different Engineering Colleges of India located in Gujarat. Based on a comprehensive survey conducted across the Engineering Colleges with over 850 respondents, this study is a quantitative analysis of the findings and preferences articulated by students and faculty members. The questions pertain to the use and features of e content such as NPTEL used by students. Questions related to faculty quality, need for online educational services, content, technologies, pedagogies, research and extension are also posed to the sample. The responses of 287 NPTEL users out of the 875 respondents are compared across gender, institution, income level and such other factors. The responses are also tested for hypothesis analyses and other analysis such as factor analysis etc. The results and findings of the paper can be of use for further modifications and modeling of NPTEL for phase II.

Bilirubin toxicity to the central nervous system (CNS) is responsible for severe and permanent neurologic damage, resulting in hearing loss, cognitive, and movement impairment. Timely and effective management of severe neonatal hyperbilirubinemia by phototherapy or exchange transfusion is crucial for avoiding permanent neurological consequences, but these therapies are not always possible, particularly in low-income countries. To explore alternative options, we investigated a pharmaceutical approach focused on protecting the CNS from pigment toxicity, independently from serum bilirubin level. To this goal, we tested the ability of curcumin, a nutraceutical already used with relevant results in animal models as well as in clinics in other diseases, in the Gunn rat, the spontaneous model of neonatal hyperbilirubinemia. Curcumin treatment fully abolished the landmark cerebellar hypoplasia of Gunn rat, restoring the histological features, and reverting the behavioral abnormalities present in the hyperbilirubinemic rat. The protection was mediated by a multi-target action on the main bilirubin-induced pathological mechanism ongoing CNS damage (inflammation, redox imbalance, and glutamate neurotoxicity). If confirmed by independent studies, the result suggests the potential of curcumin as an alternative/complementary approach to bilirubin-induced brain damage in the clinical scenario.

Following the increase in life expectancy, the prevalence of Parkinson’s disease (PD) as the most common movement disorder is expected to rise. Despite the incredibly huge efforts in research to find the definitive biomarker, to date, the diagnosis of PD still relies mainly upon clinical symptoms. A wide range of treatments is available for PD, mainly alleviating the clinical symptoms. However, none of these current therapies can stop or even slow down the disease evolution. Hence, disease-modifying treatment is still a paramount unmet medical need. On the other side, bilirubin and its enzymatic machinery and precursors have offered potential benefits by targeting multiple mechanisms in chronic diseases, including PD. Nevertheless, only limited discussions are available in the context of neurological conditions, particularly in PD. Therefore, in this review, we profoundly discuss this topic to understand bilirubin’s therapeutical potential in PD.