4 results on '"Kenan UĞURLU"'
Search Results
2. Factors Affecting Inadequate Empirical Antimicrobial Therapy and the Clinical Course of Upper Urinary Tract Infections in Elderly Patients: A Multicenter Study
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Pınar KORKMAZ, Behice KURTARAN, Şule ÖZDEMİR ARMAĞAN, Hale TURAN ÖZDEN, Fatma KAÇAR, Selma ATEŞ, Gül DURMUŞ, Fulya BAYINDIR BİLMAN, Yeşim UYGUN KIZMAZ, Aziz Ahmad HAMİDİ, Burcu ÖZDEMİR, Aslıhan BURCU YIKILGAN, Pınar FIRAT, Asuman İNAN, Gülay OKAY, Mehmet Emirhan IŞIK, Ayşe BUT, Kenan UĞURLU, Rezan HARMAN, Büşra ERGÜT SEZER, Elif DOYUK KARTAL, Ferit KUŞÇU, Alper ŞENER, Duru MISTANOĞLU ÖZATAĞ, Elif TÜKENMEZ TİGEN, Özgür DAĞLI, Funda KOÇAK, Hülya KUŞOĞLU, Buket ERTÜRK ŞENGEL, Aslıhan DEMİREL, Hasan NAZ, Canan AĞALAR, Derya ÖZTÜRK ENGİN, İlyas DÖKMETAŞ, Nur CANCAN GÜRSUL, Fatma YILMAZ KARADAĞ, Mehmet Umut ÇAYIRÖZ, Yeşim KÜREKÇİ, Ayten KADANALI, Zeynep Şule ÇAKAR, Ümit SAVAŞÇI, İlknur ERDEM, Sabahat ÇAĞAN AKTAŞ, and Acibadem University Dspace
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Urinary tract infection ,lcsh:R ,lcsh:Medicine ,lcsh:RC109-216 ,antibiotherapy ,empirical ,mortality ,lcsh:Infectious and parasitic diseases - Abstract
Introduction: In this study, we aimed to determine the risk factors associated with inadequate empirical antibiotherapy (IEAT) and hospital-related mortality in elderly patients being treated for upper urinary tract infections (UTI). Materials and Methods: This study included individuals aged 65 years and over who were hospitalized after being diagnosed of communityacquired UTI or community-onset healthcare-associated UTI and followed-up in clinics and/or intensive care units (ICU) of 33 hospitals between March and September 2017. Results: A total of 525 patients (48% males; mean age: 76.46±7.93 years) were included in the study. Overall, 68.2% of the patients were hospitalized through the emergency department and 73.9% of patients were followed-up for pyelonephritis. Gram-negative, Gram-positive, and Gram-negative and positive mix growths were determined in 88%, 9.3%, and 2.7% of urine cultures, respectively. Fifty-six (10.7%) of the patients died. In multivariate analysis, the presence of chronic obstructive pulmonary disease [Odds ratio (OR): 2.278], age 85 years and over (OR: 2.816), admission to the ICU (OR: 14.831), and IEAT (OR: 2.364) were independent factors that significantly affected mortality. The presence of a urinary catheter, being followed-up in the ICU, benign prostate hypertrophy, use of antibiotics other than piperacillin-tazobactam and carbapenem were determined as independent factors that significantly affected IEAT (p
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- 2020
3. Risk factors for recurrences in patients with hepatitis C virus after achieving a sustained virological response: a multicentre study from Turkey
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Ferhat, Arslan, Bahadir, Ceylan, Ahmet, Riza Sahin, Özgür, Günal, Bircan, Kayaaslan, Kenan, Uğurlu, Alpaslan, Tanoğlu, Gülsen, Iskender, Selma, Tosun, Aynur, Atilla, Fatma, Sargin, Ayse, Batirel, Ergenekon, Karagöz, Abdullah, Sonsuz, and Ali, Mert
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Male ,Sustained Virologic Response ,Turkey ,Recurrence ,Risk Factors ,Humans ,Female ,Hepatitis C, Chronic ,Middle Aged ,Retrospective Studies - Abstract
In this study, we aimed to determine the late relapse rate in hepatitis C patients with sustained virological response after interferon-based regimens, and evaluated the predictors of late relapse while comparing the real-life data of our country with that of others. A multicenter retrospective study was performed to investigate the data of patients infected with HCV who obtained sustained virological response after classical or pegylated interferon alpha (PegIFNα) and ribavirin (RBV) for 48 weeks. Sustained virological response was based on negative HCV RNA level by PCR at the end of six months after the therapy. The information of patients enrolled in the study was retrieved from the hospital computer operating system and outpatient follow-up archives. We evaluated the age, gender, HCV RNA levels, HCV genotype, six-month and further follow-up of patients with sustained virologic response, presence of cirrhosis, steatosis and relapse. In all, 606 out of 629 chronic hepatitis C patients (mean age was 53±12 years; 57.6% of them were female) with sustained virological response were evaluated. We excluded 23 patients who relapsed within six months after the end of treatment (EOT). The mean follow-up period of the patients was 71 months (range: 6-136) after therapy. Late relapse rate was 1.8% (n=11) in all patients. Univariate Cox proportional hazard regression models identified that cirrhosis and steatosis were associated with the late relapse [(p = 0.027; Hazard Ratio (HR) 2.328; 95% confidence interval (CI): 1.309-80.418), (p = 0.021; HR 1.446; 95% CI: 1.243-14.510, respectively]. In multivariable Cox regression analysis, steatosis was the only independent risk factor for late relapse (p = 0.03; HR 3.953; 95% CI: 1.146-13.635). Although the late relapse rate was approximately 2% in our study, clinicians should consider that pretreatment steatosis may be an important risk factor for late relapse.
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- 2018
4. Türkiye’deki yoğun bakım ünitelerinde hemşire işgücü yeterli mi? Çok merkezli karia çalışmasının sonuçları
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Alpay Ari, Yeşim Kürekçi, Fatmanur Pepe, Handan Alay, Funda Kocak, Mehmet Uçar, Selçuk Özger, Türkkan Öztürk Kaygusuz, Serpil Erol, Rezan Harman, Ramazan Gözüküçük, Güleser Ünsal, Oğuz Reşat Sipahi, Sema Sarı, Ilknur Esen Yildiz, Gül Durmuş, Meliha Meriç Koç, Nefise Oztoprak, Kenan Uğurlu, Aslıhan Demirel, Sevil Alkan Çeviker, Şirin Menekşe, Güven Çelebi, Nilgün Doğan, Ayşe Uyan, Meltem Taşbakan, Firdevs Aksoy, Nurbanu Sezak, Mustafa Doğan, Hilal Sipahi, Pınar Firat, Kevser Ozdemir, Gunes Senol, Sercan Ulusoy, Bilgin Arda, Kübra Demiray, Derya Çağlayan, İrem Akdemir, Sabahat Çağan Aktaş, Ahsen Oncul, Mustafa Arslan, Haluk Erdoğan, Hulya Caskurlu, Özlem Kandemir, Habibe Tülin Elmaslar Mert, Emre Güven, Ege Üniversitesi, RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Yıldız, İlknur Esen, Zonguldak Bülent Ecevit Üniversitesi, and MERİÇ KOÇ, MELİHA
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Microbiology (medical) ,Healthcare associated infections ,Infection control ,infection ,healthcare-associated infections ,intensive care infections ,health care facilities, manpower, and services ,education ,lcsh:Medicine ,Healthcare-associated infections ,lcsh:Infectious and parasitic diseases ,Nursing ,Infection control practitioner ,Intensive care ,Medicine ,lcsh:RC109-216 ,Intensive care infections ,integumentary system ,General Immunology and Microbiology ,business.industry ,lcsh:R ,infection control practitioner ,Infectious Diseases ,Workforce ,Uyan A., Durmus G., Sezak N., Pepe F., Kaygusuz T., Oztoprak N., Ozdemir K., AKSOY F., Erol S., Koc M., et al., -Is Nurse Workforce Sufficient in Intensive Care Units in Turkey. Results of the Multicenter Karia Study-, MEDITERRANEAN JOURNAL OF INFECTION MICROBES AND ANTIMICROBIALS, cilt.6, 2017 ,business ,Infection - Abstract
Introduction: In this multicenter study, we analysed the magnitude of healthcare worker (HCW) [infection control practitioner (ICP), nurses and others] workforce in hospitals participated in the study., Materials and Methods: This study was performed in 41 hospitals (with intensive care units-ICU) located in 22 cities from seven regions of Turkey. We analysed the ICP workforce, nursing and auxiliary HCW (AHCW) workforce in ICUs, number of ICU beds and occupied beds in four different days [two of which were in summer during the vacation time (August 27 and 31, 2016) and two others in autumn (October 12 and 15, 2016)]. The Turkish Ministry of Health (TMOH) requires two patients per nurse in level 3 ICUs, three patients per nurse in level 2 ICUs and five patients per nurse in level 1 ICUs. There is no standardization for the number of AHCW in ICUs. Finally, one ICP per 150 hospital beds is required by TMOH., Results: The total number of ICUs, ICU beds and ICPs were 214, 2377 and 111, respectively in he 41 participated centers. The number ICPs was adequate only in 12 hospitals. The percentage of nurses whose working experience was 2. The number of patients per other HCW was minimum 3.75 and maximum 4.89 on weekdays and on day shift while it was minimum 5.02 and maximum 7.7 on weekends or on night shift. When we compared the number of level 1, 2 and 3 ICUs with adequate nursing workforce vs inadequate nursing workforce, the p value was, Conclusion: Our data suggest that ICP workforce is inadequate in Turkey. Besides, HCW workforce is inadequate and almost 1/4 of nurses are relatively inexperienced especially in level 3 ICUs. Turkish healthcare system should promptly make necessary arrangements for adequate HCW staffing.
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- 2017
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