1. The effect of time since stroke, gender, age, and lesion size on thalamus volume in chronic stroke: a pilot study
- Author
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Amy D. Rodriguez, Joe R. Nocera, Amanda Garcia, Bruce Crosson, Zvinka Z. Zlatar, Stacy M. Harnish, Lisa C. Krishnamurthy, Aaminah Turabi, Jonathan Trinastic, Atchar Sudhyadhom, Michael R. Borich, Steven A. Kautz, Keith M. McGregor, Michelle L. Harris-Love, Michelle Benjamin, Jonathan H. Drucker, Venkatagiri Krishnamurthy, M. Lawson Meadows, Chris M. Gregory, Simone R. Roberts, Gabriell N. Champion, Rachael M. Harrington, Lauren Seeds, Andrew J. Butler, Carolynn Patten, and Samir Belagaje
- Subjects
Adult ,Male ,medicine.medical_specialty ,Time Factors ,Science ,Thalamus ,Pilot Projects ,Models, Biological ,Article ,050105 experimental psychology ,Lesion ,03 medical and health sciences ,0302 clinical medicine ,Text mining ,Internal medicine ,medicine ,Humans ,0501 psychology and cognitive sciences ,Chronic stroke ,Stroke ,Aged ,Aged, 80 and over ,Multidisciplinary ,business.industry ,05 social sciences ,Age Factors ,Retrospective cohort study ,Organ Size ,Middle Aged ,medicine.disease ,Additional research ,Neurology ,Chronic Disease ,Cardiology ,Medicine ,Female ,medicine.symptom ,business ,030217 neurology & neurosurgery ,Volume (compression) - Abstract
Recent stroke studies have shown that the ipsi-lesional thalamus longitudinally and significantly decreases after stroke in the acute and subacute stages. However, additional considerations in the chronic stages of stroke require exploration including time since stroke, gender, intracortical volume, aging, and lesion volume to better characterize thalamic differences after cortical infarct. This cross-sectional retrospective study quantified the ipsilesional and contralesional thalamus volume from 69 chronic stroke subjects’ anatomical MRI data (age 35–92) and related the thalamus volume to time since stroke, gender, intracortical volume, age, and lesion volume. The ipsi-lesional thalamus volume was significantly smaller than the contra-lesional thalamus volume (t(68) = 13.89, p
- Published
- 2020